anti-Calreticulin (CALR) Antikörper

Bezeichnung:
anti-Calreticulin Antikörper (CALR)
Auf www.antikoerper-online.de finden Sie aktuell 302 Calreticulin (CALR) Antikörper von 30 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Calreticulin Kits (61) und Calreticulin Proteine (49) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 431 Calreticulin Produkte verfügbar.
Synonyme:
anon-EST:fe3D7, anon-EST:Liang-2.11, anon-EST:Liang-2.17, CALR, Calregulin, cC1qR, CG9429, clone 2.11, clone 2.17, Clr, crc, CRP55, CRT, Dmel\\CG9429, ERp60, eth, HACBP, NV19007, potp, RO, SSA, zgc:85636

Meistgesuchte Reaktivitäten zu anti-Calreticulin (CALR) Antikörper

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anti-Human Calreticulin Antikörper:

anti-Mouse (Murine) Calreticulin Antikörper:

anti-Rat (Rattus) Calreticulin Antikörper:

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Am meisten referenzierte anti-Calreticulin Antikörper

  1. Human Monoclonal Calreticulin Primary Antibody für WB - ABIN394076 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Zeige alle 5 Referenzen für 394076

  2. Human Monoclonal Calreticulin Primary Antibody für IF, WB - ABIN968752 : Ito, Seyama, Kubota: Calreticulin is directly involved in anti-alpha3 integrin antibody-mediated secretion and activation of matrix metalloprotease-2. in Biochemical and biophysical research communications 2001 (PubMed)
    Zeige alle 4 Referenzen für 968752

  3. Dog (Canine) Polyclonal Calreticulin Primary Antibody für IF, IHC (p) - ABIN265295 : Kageyama, Isono, Matsuda, Ushio, Satomura, Terai, Arai, Kawakita, Okada, Yoshiki: Urinary calreticulin in the diagnosis of bladder urothelial carcinoma. in International journal of urology : official journal of the Japanese Urological Association 2009 (PubMed)
    Zeige alle 3 Referenzen für 265295

  4. Human Polyclonal Calreticulin Primary Antibody für FACS, IF (p) - ABIN759731 : Chen, Wu, Xu, Xu: Calreticulin Binds to Fas Ligand and Inhibits Neuronal Cell Apoptosis Induced by Ischemia-Reperfusion Injury. in BioMed research international 2015 (PubMed)
    Zeige alle 3 Referenzen für 759731

  5. Dog (Canine) Polyclonal Calreticulin Primary Antibody für IHC, WB - ABIN2779285 : Urade, Okudo, Kato, Moriyama, Arakaki: ER-60 domains responsible for interaction with calnexin and calreticulin. in Biochemistry 2004 (PubMed)
    Zeige alle 2 Referenzen für 2779285

  6. Human Monoclonal Calreticulin Primary Antibody für ICC, IHC - ABIN1724687 : Tan, Chen, Li, Mabuchi, Bouvier: The calcium- and zinc-responsive regions of calreticulin reside strictly in the N-/C-domain. in Biochimica et biophysica acta 2006 (PubMed)

  7. Human Polyclonal Calreticulin Primary Antibody für FACS, IF (p) - ABIN886210 : Angelova, Grekova, Heller, Kuhlmann, Soyka, Giese, Aprahamian, Bour, Rüffer, Cziepluch, Daeffler, Rommelaere, Werner, Raykov, Giese: Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer. in Journal of virology 2014 (PubMed)

  8. Human Polyclonal Calreticulin Primary Antibody für FACS, IHC (p) - ABIN390885 : Alur, Nguyen, Eggener, Jiang, Dadras, Stern, Kimm, Roehl, Kozlowski, Pins, Michalak, Dhir, Wang: Suppressive roles of calreticulin in prostate cancer growth and metastasis. in The American journal of pathology 2009 (PubMed)

Weitere Antikörper gegen Calreticulin Interaktionspartner

Fruit Fly (Drosophila melanogaster) Calreticulin (CALR) Interaktionspartner

  1. Calreticulin plays a key role in olfactory system function, possibly by establishing its overall sensitivity to odorants.

  2. Calreticulin mediates hypersensitivity to diethylether and resistance to isoflurane in association with low expression of the gene.

  3. These results collectively indicate that calreticulin is the first molecule to be identified as a marker for phagocytosis of apoptotic cells by Drosophila phagocytes

Human Calreticulin (CALR) Interaktionspartner

  1. Mannan-binding lectin (MBL (zeige MBL2 Antikörper)) bound to T cells through interaction between the collagen-like region of MBL (zeige MBL2 Antikörper) and calreticulin (CRT) expressed on the T-cell surface.

  2. CRT (zeige SLC6A8 Antikörper) exposure represents a novel powerful prognostic biomarker for patients with acute myeloid leukemia (zeige BCL11A Antikörper).

  3. In absence of CALR, immature MPO (zeige MPO Antikörper) protein precursors are degraded in the proteasome.

  4. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  5. Coexisting mutations of the JAK2 (zeige JAK2 Antikörper), CALR, and MPL (zeige MPL Antikörper) genes in myeloproliferative neoplasms suggest that CALR and MPL (zeige MPL Antikörper) should be analyzed not only in JAK2 (zeige JAK2 Antikörper)-negative patients but also in low V617F mutation patients.

  6. CALR-mutated essential thrombocythemia (ET) patients harbored a higher mutant load at progenitor level than JAK2V617F-positive ET (HSCs: 39.9% vs 7.5% p<0.001, hematopoietic stem cells)

  7. Results indicate that NGF (zeige NGFB Antikörper) inhibited CRT (zeige SLC6A8 Antikörper) translocation induced by mitoxantrone. NGF (zeige NGFB Antikörper) effect on CRT (zeige SLC6A8 Antikörper) translocation could have consequences in immunotherapy, potentially lessening the effectiveness of this type of treatment.

  8. The consistent association between Calr and Dio2 (zeige DIO2 Antikörper) expression suggests that enhanced expression of these two genes facilitate detrimental effects on cartilage integrity.

  9. The myeloproliferative neoplasms (MPNs) patients carrying Calreticulin(CALR) mutations presented with higher platelet counts and lower hemoglobin (zeige HBB Antikörper) levels compared to those with mutated JAK2 (zeige JAK2 Antikörper). However, all of the leukemia patients had negative results for CALR mutations.

  10. Alterated IQGAP1 (zeige IQGAP1 Antikörper)/Rho GTPase (zeige RACGAP1 Antikörper) signaling in myeloproliferative neoplasm erythrocytes is dependent on JAK2 (zeige JAK2 Antikörper)/CALR mutational status.

Rabbit Calreticulin (CALR) Interaktionspartner

  1. These findings suggest that protein kinase C (zeige PKC Antikörper) is involved in the regulation of CRT function.

Mouse (Murine) Calreticulin (CALR) Interaktionspartner

  1. study provides a model showing that the C-terminal of mutant CALR activated JAK (zeige JAK3 Antikörper)-STAT (zeige STAT1 Antikörper) signaling specifically downstream of MPL (zeige MPL Antikörper) and may have a central role in CALR-induced myeloproliferative neoplasms

  2. the results of this investigation provide the first molecular insights into the phospholipid binding site of calreticulin as a key anchor point for the cell surface expression of calreticulin on apoptotic cells

  3. a profound impairment in calreticulin function when its lectin site was inactivated. Remarkably, inactivation of the polypeptide binding site had little impact. These findings indicate that the lectin-based mode of client interaction is the predominant contributor to the chaperone functions of calreticulin within the endoplasmic reticulum.

  4. This essential role of calreticulin in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  5. Study provides evidence that chronic stress activates calreticulin and might be one of the pathological mechanisms underlying the motor coordination and motor learning dysfunctions seen in social defeat mice.

  6. This study for the first time revealed that increased CRT (zeige SLC6A8 Antikörper) inhibited Fas (zeige FAS Antikörper)/FasL (zeige FASL Antikörper)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  7. The findings highlight the importance of CALR in female reproduction and demonstrate that compromised CALR function leads to ovarian insufficiency and female infertility.

  8. Calreticulin mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  9. CALR mutants are sufficient to induce thrombocytosis through MPL (zeige MPL Antikörper) activation.

  10. Thrombopoietin receptor (zeige MPL Antikörper) activation by myeloproliferative neoplasm associated calreticulin mutants.

Cow (Bovine) Calreticulin (CALR) Interaktionspartner

  1. the lectin site of CRT is the main target for gentamicin binding

Pig (Porcine) Calreticulin (CALR) Interaktionspartner

  1. Calreticulin is confined to subplasmalemmal vesicles partially overlapping with cortical granule contents. Its exocytosis after the oocyte activation seems to participate in the membrane block to polyspermy in pigs.

  2. Calreticulin was widely expressed in pig tissues and its transcripts were downregulated during maturation, especially at 44 hr, and were undetectable at the blastocyst stage.

Calreticulin (CALR) Antigen-Profil

Beschreibung des Gens

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin but calreticulin is not a Ro/SS-A antigen. Earlier papers referred to calreticulin as an Ro/SS-A antigen but this was later disproven. Increased autoantibody titer against human calreticulin is found in infants with complete congenital heart block of both the IgG and IgM classes.

Alternative names and synonyms associated with Calreticulin (CALR)

  • calreticulin (calr) Antikörper
  • calreticulin (crt) Antikörper
  • calreticulin (CRT) Antikörper
  • Calreticulin (Crc) Antikörper
  • calreticulin (LmjF31.2600) Antikörper
  • calreticulin (Crc) Antikörper
  • calreticulin (CALR) Antikörper
  • calreticulin (Calr) Antikörper
  • calreticulin (Crt) Antikörper
  • calreticulin 2, calcium-binding protein (CRT2) Antikörper
  • calreticulin 3 (CALR3) Antikörper
  • anon-EST:fe3D7 Antikörper
  • anon-EST:Liang-2.11 Antikörper
  • anon-EST:Liang-2.17 Antikörper
  • CALR Antikörper
  • Calregulin Antikörper
  • cC1qR Antikörper
  • CG9429 Antikörper
  • clone 2.11 Antikörper
  • clone 2.17 Antikörper
  • Clr Antikörper
  • crc Antikörper
  • CRP55 Antikörper
  • CRT Antikörper
  • Dmel\\CG9429 Antikörper
  • ERp60 Antikörper
  • eth Antikörper
  • HACBP Antikörper
  • NV19007 Antikörper
  • potp Antikörper
  • RO Antikörper
  • SSA Antikörper
  • zgc:85636 Antikörper

Bezeichner auf Proteinebene für anti-Calreticulin (CALR) Antikörper

calreticulin , CG9429-PA , CG9429-PB , Crc-PA , Crc-PB , anon-fast-evolving-3D7 , pot pourri , potpourri , ER-resident chaperone calreticulin , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , CABP3 , CALBP , calcium-binding protein 3 , calrectulin , Endoplasmic reticulum resident protein 60

GENE ID SPEZIES
379788 Xenopus laevis
100136202 Oncorhynchus mykiss
100146083 Triticum aestivum
30248 Danio rerio
41166 Drosophila melanogaster
407962 Xenopus (Silurana) tropicalis
5654192 Leishmania major strain Friedlin
100116123 Nasonia vitripennis
100304608 Ictalurus punctatus
811 Homo sapiens
476694 Canis lupus familiaris
100009050 Oryctolagus cuniculus
12317 Mus musculus
64202 Rattus norvegicus
281036 Bos taurus
100381266 Sus scrofa
101104396 Ovis aries
100713922 Cavia porcellus
692629 Bombyx mori
100689096 Cricetulus griseus
5715514 Chlamydomonas reinhardtii
420146 Gallus gallus
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