anti-SOX8 (SOX8) Antikörper

Auf finden Sie aktuell 91 SRY (Sex Determining Region Y)-Box 8 (SOX8) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SOX8 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 103 SOX8 Produkte verfügbar.
Alle Antikörper anzeigen Gen GeneID UniProt
SOX8 30812 P57073
SOX8 302993  
SOX8 20681 Q04886

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Weitere Antikörper gegen SOX8 Interaktionspartner

Human SRY (Sex Determining Region Y)-Box 8 (SOX8) Interaktionspartner

  1. In non-small cell lung cancer, SOX8 expression was elevated, and correlated with tumor size, lymph node metastasis, clinical stage and differentiation classification.

  2. Suggest that miRNA-124 may regulate non-small cell lung carcinoma cell proliferation via decreasing SOX8.

  3. SOX8 mRNA levels decrease during in vitro dedifferentiation of human articular chondrocytes and increase during chondrogenic differentiation of mesenchymal stromal cells.

  4. SOX8 promotes cancer cell proliferation and its expression is correlated with elevated beta-catenin (zeige CTNNB1 Antikörper) levels in hepatocellular carcinoma

  5. The SOX8 single nucleotide polymorphism, rs2744148, is associated with increased genetic risk for multiple sclerosis.

  6. Quantitative changes of enteric glia represented by SOX8 provide a basis for pathological assessment of glial proliferation and/or degeneration in the diseased gut (zeige GUSB Antikörper).

  7. SOX2 (zeige SOX2 Antikörper) and SOX17 (zeige SOX17 Antikörper) expression patterns can distinguish between seminoma and embryonal carcinoma, and this distinction may be diagnostically useful.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 8 (SOX8) Interaktionspartner

  1. Binding of mrhl RNA to the Sox8 promoter is accompanied by the assembly of other regulatory factors involving Myc (zeige MYC Antikörper)-Max-Mad transcription factors, corepressor Sin3a (zeige SIN3A Antikörper), and coactivator Pcaf (zeige KAT2B Antikörper)

  2. These results suggest that Sox8 is essential in Sertoli cells for germ cell differentiation, partly by controlling the microenvironment of the seminiferous epithelium.

  3. combined RNA profiling signals, motif predictions and network data identified putative SOX8/SOX9 (zeige SOX9 Antikörper) target genes in Sertoli cells and yielded insight into regulatory interactions that depend upon these transcription factors

  4. Sox9 (zeige SOX9 Antikörper) and Sox8 maintain integrity of the basal lamina to prevent testis cord disintegration and both factors actively suppress the ovarian program during early testis development.

  5. Seven regions near the Sox8 gene as potential enhancers, were identified.

  6. SOX8 has a role in testis differentiation in mice and synergizes with SF1 (zeige SF1 Antikörper) to activate the Amh (zeige AMH Antikörper) promoter in vitro

  7. Sox8 acts as a specific negative regulator of skeletal muscle differentiation, possibly by interfering with the function of myogenic basic helix-loop-helix proteins

  8. Results suggest that Sox8 reinforces Sox9 (zeige SOX9 Antikörper) function in testis differentiation of mice.

  9. Sox8-deficient mice thus exhibited a similar, but less severe phenotype than did Sox10 (zeige SOX10 Antikörper)-deficient mice wiwth regard to oligodendrocyte differentiation.

  10. The defects in enteric nervous system development of mice with Sox10 (zeige SOX10 Antikörper) and Sox8 mutations are caused by a reduction of the pool of undifferentiated vagal neural crest cells.

SOX8 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).

Alternative names and synonyms associated with SOX8

  • SRY (sex determining region Y)-box 8 (SOX8) Antikörper
  • SRY (sex determining region Y)-box 8 (Sox8) Antikörper
  • SRY (sex determining region Y)-box 8 (sox8) Antikörper
  • SRY-box containing gene 8 (Sox8) Antikörper

Bezeichner auf Proteinebene für SOX8

transcription factor SOX-8 , SRY-box containing gene 8 , transcription factor Sox-8 , SOX8 transcription factor

30812 Homo sapiens
302993 Rattus norvegicus
399214 Xenopus laevis
490082 Canis lupus familiaris
395483 Gallus gallus
530317 Bos taurus
20681 Mus musculus
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