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N-Cadherin Proteine (CDH2)

Cadherin 2 Proteine (CDH2)
Auf finden Sie aktuell 15 Cadherin 2 (CDH2) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen N-Cadherin Antikörper (396) und N-Cadherin Kits (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 460 N-Cadherin Produkte verfügbar.
Cadherin-2, CD325, CDH2, CDHN, CDw325, glo, lyr, N-cadherin, NCAD, pac, wu:fb47h04
alle Proteine anzeigen Gen GeneID UniProt
CDH2 12558 P15116
Ratte CDH2 CDH2 83501 Q9Z1Y3
CDH2 1000 P19022

Weitere Synonyme anzeigen

N-Cadherin Proteine (CDH2) nach Spezies

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Am meisten referenzierte N-Cadherin Proteine

  1. Human N-Cadherin Protein expressed in Human Cells - ABIN2003757 : LaMora, Voigt: Cranial sensory ganglia neurons require intrinsic N-cadherin function for guidance of afferent fibers to their final targets. in Neuroscience 2009 (PubMed)
    Zeige alle 5 Referenzen für ABIN2003757

  2. Human N-Cadherin Protein expressed in Baculovirus infected Insect Cells - ABIN2003756 : Chauvet, El-Yandouzi, Mathieu, Schlernitzauer, Galibert, Lafont, Le Tissier, Robinson, Mollard, Coutry: Characterization of adherens junction protein expression and localization in pituitary cell networks. in The Journal of endocrinology 2009 (PubMed)
    Zeige alle 4 Referenzen für ABIN2003756

  3. Mouse (Murine) N-Cadherin Protein expressed in Human Cells - ABIN2008273 : Hartland, Murphy, Aucott, Abergel, Zhou, Waung, Patel, Bradshaw, Collins, Mann, Benyon, Iredale: Active matrix metalloproteinase-2 promotes apoptosis of hepatic stellate cells via the cleavage of cellular N-cadherin. in Liver international : official journal of the International Association for the Study of the Liver 2009 (PubMed)
    Zeige alle 4 Referenzen für ABIN2008273

  4. Human N-Cadherin Protein expressed in Human Cells - ABIN2003753 : Kohutek, diPierro, Redpath, Hussaini: ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Zeige alle 4 Referenzen für ABIN2003753

Weitere Proteine zu N-Cadherin Interaktionspartnern

Xenopus laevis Cadherin 2 (CDH2) Interaktionspartner

  1. the switch from E- to N-cadherin during epithelial-mesenchymal transition is essential for acquisition of Contact inhibition of locomotion behavior.

Mouse (Murine) Cadherin 2 (CDH2) Interaktionspartner

  1. Knock-down of ZBED6 in insulin (zeige INS Proteine)-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.

  2. Knockdown of N-cadherin in 3T3 fibroblasts did not impede gap closure in a soft tissue wound healing model.

  3. N-cadherin modulates Lrp6 (zeige LRP6 Proteine)/PTHR1 (zeige PTH1R Proteine) interaction, restraining the intensity of parathyroid hormone (zeige PTH Proteine)-induced beta-catenin (zeige CTNNB1 Proteine) signaling

  4. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice.

  5. CRP (zeige CRP Proteine) suppresses expression of N-cadherin (p < 0.01), a mesenchymal marker of EMT (zeige ITK Proteine), and ZEB-1, an EMT (zeige ITK Proteine)-related transcription factor (p < 0.01). These findings suggest that CRP (zeige CRP Proteine) inhibits EMT (zeige ITK Proteine) in a MCA (zeige RSPH1 Proteine)-38 tumor-bearing mouse model.

  6. these studies suggest that N-cadherin may represent a viable therapeutic target to prevent the dissemination of MM PCs and delay MM disease progression.

  7. N-cadherin is required for the establishment and maintenance of anterior heart field -cardiac progenitor cells.

  8. delta-Catenin Regulates Spine Architecture via Cadherin and PDZ-dependent Interactions.

  9. Results demonstrate a novel function for the N-cadherin/beta-catenin (zeige CTNNB1 Proteine) complex in regulating ionotropic receptor composition of excitatory synapses

  10. N-cadherin is not essential for healthy enamel development and does not significantly affect the mineralization process.

Zebrafish Cadherin 2 (CDH2) Interaktionspartner

  1. Throughout somitogenesis, Cadherin2 promotes extracellular matrix (ECM (zeige MMRN1 Proteine)) assembly along tissue boundaries and inhibits ECM (zeige MMRN1 Proteine) assembly in the tissue mesenchyme.

  2. Cdon (zeige CDON Proteine) is required to localize N-cadherin to the cell membrane in migratory neural crest cells for directed migration.

  3. shows that a dominant-negative nuclear localization mutant of Sox3 (zeige SOX3 Proteine) can cause ectopic expression of organizer genes via a mechanism that activates all of these earlier factors, resulting in later axis duplication including major bifurcations of the CNS.

  4. Genetic suppression of N-cadherin function interferes with basal migration of retinal progenitors and subsequent regeneration of HuC (zeige ELAVL3 Proteine)/D(+) inner retinal neurons.

  5. N-cadherin deficiency in Danio does not prevent the first tooth from starting to develop, but stops its development at the early cytodifferentiation stage and completely inhibits the development of the other first-generation teeth.

  6. N-cadherin regulates motor axon growth and branching without severely affecting the mechanisms that control axonal target selection.

  7. Slit-Robo signaling downregulates N-cadherin activity to allow apical retraction in newly generated retinal ganglion cells.

  8. demonstration of a novel mechanism of cell adhesion, mediated by a complex of Protocadherin-19 (Pcdh19 (zeige PCDH19 Proteine)) and N-cadherin (Ncad)

  9. zebrafish N-cadherin restricts cell proliferation in the dorsal region of the neural tube by regulating cell-cycle length.

  10. Protocadherin-19 (zeige PCDH19 Proteine) and N-cadherin interact to control cell movements during anterior neurulation

Human Cadherin 2 (CDH2) Interaktionspartner

  1. NKX6.1 (zeige NKX6-1 Proteine) directly enhances the mRNA level of E-cadherin (zeige CDH1 Proteine) by recruiting BAF155 (zeige SMARCC1 Proteine) coactivator and represses that of vimentin (zeige VIM Proteine) and N-cadherin by recruiting RBBP7 (retinoblastoma binding protein 7 (zeige RBBP7 Proteine)) corepressor.

  2. Impairment of E-cadherin (zeige CDH1 Proteine)/N-cadherin adhesion abrogates the ability of Cancer-associated fibroblasts to guide collective cell migration and blocks cancer cell invasion.

  3. These data implicate CDH2 mutations as novel genetic causes of Arrhythmogenic Right Ventricular Cardiomyopathy and contribute to a more complete identification of disease genes involved in cardiomyopathy.

  4. High expression of N-cadherin is associated with bladder cancer.

  5. Snail (zeige SNAI1 Proteine) and N-cadherin are constitutively and inducibly expressed in papillary thyroid carcinoma

  6. SFMSCs increased through upregulation of the activated lymphocyte cell adhesion molecule (zeige MCAM Proteine) (ALCAM (zeige ALCAM Proteine)) and N-cadherin by microRNA-192 and -218 downregulation, similar to BMMSCs and ADMSCs.

  7. the synergy between N-cadherin and FGFR (zeige FGFR2 Proteine) signalling that ensure cellular reorganization during cell movements, mainly during cancer cell migration and metastasis but also during developmental processes.

  8. Underexpression of CDH2 is associated with adrenocortical tumors.

  9. Data show that gene silence of ezrin (zeige EZR Proteine) inhibits the proliferation and invasion of prostate cancer PC-3 (zeige PCSK1 Proteine) cells, meanwhile the level of E-cadherin (zeige CDH1 Proteine) is upregulated and N-cadherin is downregulated.

  10. These data suggest that the number of polyploid giant cancer cells and the EMT (zeige ITK Proteine)-related proteins E-cadherin (zeige CDH1 Proteine), N-cadherin, and vimentin (zeige VIM Proteine) may be valuable biomarkers to assess metastasis in patients with breast cancer.

N-Cadherin (CDH2) Protein Überblick

Protein Überblick

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Alternative names and synonyms associated with N-Cadherin (CDH2)

  • cadherin 2, type 1, N-cadherin (neuronal) (cdh2)
  • cadherin 2 (Cdh2)
  • cadherin 2, neuronal (cdh2)
  • cadherin 2, type 1, N-cadherin (neuronal) (CDH2)
  • cadherin 2, type 1, N-cadherin (neuronal) (Cdh2)
  • cadherin-2-like (LOC100411112)
  • neural-cadherin-like (LOC427547)
  • Cadherin-2 Protein
  • CD325 Protein
  • CDH2 Protein
  • CDHN Protein
  • CDw325 Protein
  • glo Protein
  • lyr Protein
  • N-cadherin Protein
  • NCAD Protein
  • pac Protein
  • wu:fb47h04 Protein

Bezeichner auf Proteinebene für Cadherin 2 Proteine (CDH2)

cadherin 2, type 1, N-cadherin (neuronal) , cadherin-2 , neural cadherin , cadherin 2 type 1 N-cadherin (neuronal) , N-cadherin , Neural cadherin , glass onion , labyrinth , n-cadherin , parachute , N-cadherin 1 , cadherin 2, N-cadherin (neuronal) , calcium-dependent adhesion protein, neuronal , neural-cadherin , cadherin 2, type 1 preproprotein , cadherin-2-like

495284 Xenopus laevis
100151712 Xenopus (Silurana) tropicalis
12558 Mus musculus
83501 Rattus norvegicus
100689204 Cricetulus griseus
30291 Danio rerio
1000 Homo sapiens
414745 Gallus gallus
281062 Bos taurus
480169 Canis lupus familiaris
100286861 Sus scrofa
101082701 Felis catus
100065078 Equus caballus
100170321 Ovis aries
100328895 Oryctolagus cuniculus
100714783 Cavia porcellus
100411112 Callithrix jacchus
427547 Gallus gallus
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