anti-HDAC4 (HDAC4) Antikörper

Bezeichnung:
anti-Histone Deacetylase 4 Antikörper (HDAC4)
Auf www.antikoerper-online.de finden Sie aktuell 341 Histone Deacetylase 4 (HDAC4) Antikörper von 37 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HDAC4 Kits (17) und HDAC4 Proteine (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 393 HDAC4 Produkte verfügbar.
Synonyme:
4932408F19Rik, AHO3, AI047285, BDMR, CG1770, DanaGF18710, dana_GLEANR_19966, dHDAC4, Dmel\\CG1770, dmHDA405, GC1770, GF18710, HA6116, HD4, HDAC, HDAC-4, HDAC-A, HDAC4, HDAC4a, HDACA, wu:fa96d08, wu:fc56f08, zgc:152701

Meistgesuchte Reaktivitäten zu anti-HDAC4 (HDAC4) Antikörper

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anti-Human HDAC4 Antikörper:

anti-Mouse (Murine) HDAC4 Antikörper:

anti-Rat (Rattus) HDAC4 Antikörper:

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Am meisten referenzierte anti-HDAC4 Antikörper

  1. Human Polyclonal HDAC4 Primary Antibody für ICC, IF - ABIN269450 : Geng, Cuneo, Fu, Tu, Atadja, Hallahan: Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer. in Cancer research 2006 (PubMed)
    Zeige alle 5 Referenzen für 269450

  2. Human Polyclonal HDAC4 Primary Antibody für EIA, WB - ABIN493047 : Bolden, Peart, Johnstone: Anticancer activities of histone deacetylase inhibitors. in Nature reviews. Drug discovery 2006 (PubMed)
    Zeige alle 5 Referenzen für 493047

  3. Human Polyclonal HDAC4 Primary Antibody für EIA, WB - ABIN356644 : Chan, Sun, Yang, Zhu, Wu: Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 5 Referenzen für 356644

  4. Human Polyclonal HDAC4 Primary Antibody für WB - ABIN387951 : Kao, McKenna, Guenther, Muschel, Lazar, Yen: Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. in The Journal of cell biology 2003 (PubMed)
    Zeige alle 2 Referenzen für 387951

  5. Human Polyclonal HDAC4 Primary Antibody für WB - ABIN196930 : Wang, Kruhlak, Wu, Bertos, Vezmar, Posner, Bazett-Jones, Yang: Regulation of histone deacetylase 4 by binding of 14-3-3 proteins. in Molecular and cellular biology 2000 (PubMed)
    Zeige alle 2 Referenzen für 196930

  6. Human Polyclonal HDAC4 Primary Antibody für IF, WB - ABIN197338 : Grozinger, Schreiber: Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Zeige alle 2 Referenzen für 197338

  7. Cow (Bovine) Polyclonal HDAC4 Primary Antibody für WB - ABIN2778341 : Lee, Lin, Luo, Lee, Lee, Aird, Hwang, Yang et al.: Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and ... in Molecular pharmacology 2008 (PubMed)

  8. Human Polyclonal HDAC4 Primary Antibody für IHC, WB - ABIN223298 : Cao, Li, Zhu, Shen, Han, Zhang, Yu, Wang, Wu, Chen, Sun, Tang, Zhao, Qiao, Hou, Mao: The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity. in The Journal of biological chemistry 2013 (PubMed)

Weitere Antikörper gegen HDAC4 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Histone Deacetylase 4 (HDAC4) Interaktionspartner

  1. We also demonstrate that HDAC4 and Ubc9 (zeige UBE2I Antikörper) interact genetically during memory formation, opening new avenues for investigating the mechanisms through which HDAC4 regulates memory formation and other neurological processes.

  2. RNAi-mediated knockdown of HDAC4 in Drosophila dampens circadian function.

  3. HDAC4 is not only a repressor of long-term memory, but also modulates normal memory formation

  4. dHDAC4, is a novel, catalytically active class II Drosophila histone deacetylase (zeige HDAC1 Antikörper) and is involved in the segmentation regulatory pathway and suggested complex transcriptional regulation as a potential mechanism that controls its expression

Human Histone Deacetylase 4 (HDAC4) Interaktionspartner

  1. level of myotubes MTM1 (zeige MTM1 Antikörper) mutations do not dramatically affect calcium homeostasis and calcium release mediated through the ryanodine receptor 1 (zeige RYR1 Antikörper), though they do affect myotube size and nuclear content..mature muscles such as those obtained from patient muscle biopsies exhibit a significant decrease in expression of the ryanodine receptor 1 (zeige RYR1 Antikörper), a decrease in muscle-specific (zeige EIF3K Antikörper) microRNAs and a considerable up-regulation of HDAC4.

  2. 7-amino-4-methylcoumarin did not affect acetyllysine preference in a multiply acetylated substrate. In contrast, AMC significantly enhanced KDAC6 substrate affinity, greatly reduced Sirt1 (zeige SIRT1 Antikörper) activity, eliminated the substrate sequence specificity of KDAC4, and had no consistent effect with KDAC8 substrates.

  3. Suggest that HDAC4 and HDAC6 (zeige HDAC6 Antikörper) are guardians of irradiation-induced DNA damage and stemness, thus promoting radioresistance in glioblastoma cells.

  4. TGF-beta1 (zeige TGFB1 Antikörper) increases NADPH oxidase 4 (NOX4 (zeige NOX4 Antikörper)) mRNA and protein expression in normal human lung fibroblasts (NHLFs) and causes nuclear export of HDAC4.

  5. elevated HO-1 (zeige HMOX1 Antikörper) produced less reactive oxygen species, resulting in nuclear localization of HDAC4 and miR (zeige MLXIP Antikörper)-206 repression.

  6. Results show that HDAC4 is a direct target of miR (zeige MLXIP Antikörper)-29b in multiple myeloma cells and its high mRNA expression inversely correlates with miR (zeige MLXIP Antikörper)-29b levels in multiple myeloma samples.

  7. in leiomyosarcomas (LMS), this two-faced trait of MEF2 (zeige MEF2A Antikörper) is relevant for tumor aggressiveness. Class IIa HDACs are overexpressed in 22% of LMS, where high levels of MEF2 (zeige MEF2A Antikörper), HDAC4 and HDAC9 (zeige HDAC9 Antikörper) inversely correlate with overall survival. The knock out of HDAC9 (zeige HDAC9 Antikörper) suppresses the transformed phenotype of LMS cells, by restoring the transcriptional proficiency of some MEF2 (zeige MEF2A Antikörper)-target loci

  8. Collectively, we suggest that VSV treatment will be a useful therapeutic strategy for HCV-infected hepatocellular carcinoma cells because HCV core protein suppresses the anti-viral threshold by down-regulation of the STAT1 (zeige STAT1 Antikörper)-HDAC4 signaling axis.

  9. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13 (zeige MMP13 Antikörper), ADAMTS-5 (zeige ADAMTS5 Antikörper), and HDAC-4, and modulates the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway activation.

  10. HDAC4 is a target gene of miR (zeige MLXIP Antikörper)-140 and is involved in miR (zeige MLXIP Antikörper)-140-mediated suppression of osteosarcoma cells.

Mouse (Murine) Histone Deacetylase 4 (HDAC4) Interaktionspartner

  1. our results imply that under steady stage, HDAC4 (zeige HDAC5 Antikörper) is not required for the development and function of multiple T cell lineages

  2. HDAC4 (zeige HDAC5 Antikörper)-mediated SUMOylation of the corepressor DACH1 (zeige DACH1 Antikörper) is decreased, which protects DACH1 (zeige DACH1 Antikörper) from proteasomal degradation

  3. The eating-disorder (ED) associated HDAC4 (zeige HDAC5 Antikörper)(A778T) mutation alters feeding behaviors in female mice. The HDAC4 (zeige HDAC5 Antikörper)(A778T) mouse line is a novel model of ED-related behaviors and identifies mitochondrial biogenesis as a potential molecular pathway contributing to behavioral deficits.

  4. Nuclear HDAC4 (zeige HDAC5 Antikörper) binds to chromatin as well as to MEF2A (zeige MEF2A Antikörper) transcription factor, leading to histone deacetylation and altered neuronal gene expression. By using a Cdkl5 (zeige CDKL5 Antikörper) knockout (Cdkl5 (zeige CDKL5 Antikörper) -/Y) mouse model, we found that hypophosphorylated HDAC4 (zeige HDAC5 Antikörper) translocates to the nucleus of neural precursor cells, thereby reducing histone 3 acetylation.

  5. Data (including data from studies using knockout mice) suggest that S100A1 (zeige S100A1 Antikörper) (S-100 calcium-binding protein (zeige GUCA1B Antikörper) A1 (zeige BCL2A1 Antikörper), alpha chain (zeige FCGRT Antikörper)) is involved in protein kinase A- (RIIalpha and RIIbeta (zeige PRKAR2B Antikörper))-dependent signaling resulting in nuclear redistribution/influx of HDAC4 (histone deacetylase 4 (zeige HDAC5 Antikörper)) in skeletal muscle fibers.

  6. results are the first to demonstrate that the protective effects of irisin (zeige FNDC5 Antikörper) in cardiomyoblasts exposed to hypoxia/reoxygenation might be associated with HDAC4 (zeige HDAC5 Antikörper) degradation.

  7. PC3/Tis21 (zeige BTG2 Antikörper) associates with HDAC1 (zeige HDAC1 Antikörper), HDAC4 (zeige HDAC5 Antikörper), and HDAC9 (zeige HDAC9 Antikörper) in vivo, in fibroblast cells.

  8. HDAC4 (zeige HDAC5 Antikörper) increases endogenous SIRT1 (zeige SIRT1 Antikörper) expression by enhancing its sumoylation modification levels

  9. postmitotic expression SOD1G93A mutant gene promotes a FAPS phenotype in C2C12 cells, by upregulating HDAC4 (zeige HDAC5 Antikörper) protein and preventing the BAF60C (zeige SMARCD3 Antikörper)-SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) complex myogenic commitment

  10. miR (zeige MLXIP Antikörper)-29a was involved in the regulation of HDAC4 (zeige HDAC5 Antikörper) and modulation of the profibrogenic phenotype in hepatic stellate cells.

Zebrafish Histone Deacetylase 4 (HDAC4) Interaktionspartner

  1. Results demonstrate that Hdac4 is a regulator of cranial neural crest-derived palatal skeletal precursors during early embryogenesis.

Cow (Bovine) Histone Deacetylase 4 (HDAC4) Interaktionspartner

  1. our results revealed the mechanism in which miR-1 and miR (zeige MYLIP Antikörper)-206 positively regulate bovine skeletal muscle satellite cell myogenic differentiation via Pax7 (zeige PAX7 Antikörper) and HDAC4 downregulation.

HDAC4 Antigen-Profil

Beschreibung des Gens

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Alternative names and synonyms associated with HDAC4

  • histone deacetylase 4 (PTRG_03699) Antikörper
  • histone deacetylase 4 (PGTG_15512) Antikörper
  • CG1770 gene product from transcript CG1770-RG (HDAC4) Antikörper
  • DanaGF18710-PA (DanaHDAC4) Antikörper
  • histone deacetylase 4 (HDAC4) Antikörper
  • histone deacetylase 4 (Hdac4) Antikörper
  • histone deacetylase 4 (hdac4) Antikörper
  • 4932408F19Rik Antikörper
  • AHO3 Antikörper
  • AI047285 Antikörper
  • BDMR Antikörper
  • CG1770 Antikörper
  • DanaGF18710 Antikörper
  • dana_GLEANR_19966 Antikörper
  • dHDAC4 Antikörper
  • Dmel\\CG1770 Antikörper
  • dmHDA405 Antikörper
  • GC1770 Antikörper
  • GF18710 Antikörper
  • HA6116 Antikörper
  • HD4 Antikörper
  • HDAC Antikörper
  • HDAC-4 Antikörper
  • HDAC-A Antikörper
  • HDAC4 Antikörper
  • HDAC4a Antikörper
  • HDACA Antikörper
  • wu:fa96d08 Antikörper
  • wu:fc56f08 Antikörper
  • zgc:152701 Antikörper

Bezeichner auf Proteinebene für HDAC4

histone deacetylase 4 , CG1770-PB , CG1770-PD , CG1770-PE , CG1770-PF , CG1770-PG , CG1770-PH , CG1770-PI , CG1770-PJ , HDAC4-PB , HDAC4-PD , HDAC4-PE , HDAC4-PF , HDAC4-PG , HDAC4-PH , HDAC4-PI , HDAC4-PJ , DanaGF18710-PA , DanaHDAC4-PA , GF18710-PA , HDAC4 , HDAC4-PA , histone deacetylase A , HD4

GENE ID SPEZIES
6341931 Pyrenophora tritici-repentis Pt-1C-BFP
10547054 Puccinia graminis f. sp. tritici CRL 75-36-700-3
32278 Drosophila melanogaster
6507946 Drosophila ananassae
9759 Homo sapiens
208727 Mus musculus
363287 Rattus norvegicus
374207 Gallus gallus
568877 Danio rerio
607662 Canis lupus familiaris
517559 Bos taurus
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