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anti-CLOCK (CLOCK) Antikörper

Bezeichnung:
anti-Clock Homolog (Mouse) Antikörper (CLOCK)
Auf www.antikoerper-online.de finden Sie aktuell 115 Clock Homolog (Mouse) (CLOCK) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CLOCK Kits (7) und CLOCK Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 135 CLOCK Produkte verfügbar.
Synonyme:
5330400M04Rik, bHLHe8, bHLHe10, CG7391, clk, clock, dClck, dclk, dCLK/JRK, dClock, Dmel\\CG7391, Jerk, jrk, KAT13D, mKIAA0334, PAS1, Xclk, XClock, zCLOCK1, zfCLOCK1

Meistgesuchte Reaktivitäten zu anti-CLOCK (CLOCK) Antikörper

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anti-Mouse (Murine) CLOCK Antikörper:

anti-Rat (Rattus) CLOCK Antikörper:

anti-Human CLOCK Antikörper:

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Am meisten referenzierte anti-CLOCK Antikörper

  1. Human Polyclonal CLOCK Primary Antibody für ChIP, WB - ABIN151057 : Jin, Shearman, Weaver, Zylka, de Vries, Reppert: A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. in Cell 1999 (PubMed)
    Zeige alle 6 Referenzen für ABIN151057

  2. Human Polyclonal CLOCK Primary Antibody für EIA, IHC (p) - ABIN359753 : Marino, Holt, Chen, Davis: Shift work, hCLOCK T3111C polymorphism, and endometriosis risk. in Epidemiology (Cambridge, Mass.) 2008 (PubMed)
    Zeige alle 3 Referenzen für ABIN359753

  3. Human Monoclonal CLOCK Primary Antibody für ICC, ELISA - ABIN969059 : Lee, Paik, Kang, Lim, Kim: Allelic variants interaction of CLOCK gene and G-protein beta3 subunit gene with diurnal preference. in Chronobiology international 2007 (PubMed)
    Zeige alle 2 Referenzen für ABIN969059

  4. Human Polyclonal CLOCK Primary Antibody für IHC, ELISA - ABIN1533501 : Steeves, King, Zhao, Sangoram, Du, Bowcock, Moore, Takahashi: Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei. in Genomics 1999 (PubMed)

  5. Human Polyclonal CLOCK Primary Antibody für ELISA, WB - ABIN564129 : Kalamvoki, Roizman: Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

Weitere Antikörper gegen CLOCK Interaktionspartner

Fruit Fly (Drosophila melanogaster) Clock Homolog (Mouse) (CLOCK) Interaktionspartner

  1. Here we demonstrate that the transcription factor CLOCKWORK ORANGE (CWO) antagonizes CLK-CYC (zeige COX6C Antikörper) E-box binding, thus enhancing the removal of CLK-CYC (zeige COX6C Antikörper) from E-boxes to maintain transcriptional repression. This process requires PER, which suggests that PER-TIM and CWO cooperate to maintain a transcriptionally repressed state by removing CLK-CYC (zeige COX6C Antikörper) from E-boxes

  2. these results demonstrate a key role of Clk post-transcriptional control in stabilizing circadian transcription.

  3. Our findings suggest a novel role for clock protein (zeige ARNTL Antikörper) phosphorylation in governing the relative strengths of entraining modalities by adjusting the dynamics of circadian gene expression.

  4. These results demonstrate that CLK phosphorylation influences the circadian period by regulating CLK activity and progression through the feedback loop.

  5. Computational dissection of CLK/CYC (zeige COX6C Antikörper) context-specific binding sites reveals sequence motifs for putative partner factors, which are predictive for individual binding sites

  6. usp8 (zeige USP8 Antikörper) loss of function (RNAi) or expression of a dominant-negative form of the protein (USP8 (zeige USP8 Antikörper)-DN) enhances CLK/CYC (zeige COX6C Antikörper) transcriptional activity and alters fly locomotor activity rhythms

  7. CLK has specific targets in different tissues, implying that important CLK partner proteins and/or mechanisms contribute to gene-specific and tissue-specific regulation

  8. CTRIP destabilizes CLK protein in a PER-independent manner and helps degradation of phosphorylated PER and TIM in the morning

  9. dPER(DeltaCBD) does not provoke the daily hyperphosphorylation of dCLOCK, indicating that direct interactions between dPER and dCLOCK are necessary for the dCLOCK phosphorylation

  10. findings show that Clk and cyc (zeige COX6C Antikörper) act during starvation to modulate the conflict of whether flies sleep or search for food

Zebrafish Clock Homolog (Mouse) (CLOCK) Interaktionspartner

  1. effect of CRY (zeige CRY2 Antikörper) in repressing transcription mediated by CLOCK-BMAL heterodimer

Mouse (Murine) Clock Homolog (Mouse) (CLOCK) Interaktionspartner

  1. These data establish the importance of circadian CLOCK-inhibin signaling in sepsis.

  2. our results indicate that Clock is a key regulator of AKT (zeige AKT1 Antikörper) signalling for triggering cardiac hypertrophy in vivo.

  3. Report altered BMAL1 (zeige ARNTL Antikörper)/CLOCK expression in conditions of chronically altered blood flow.

  4. PI3K signaling plays a modulatory role in the regulation of the transcriptional rhythm of the Dbp (zeige GC Antikörper) gene by targeting BMAL1 (zeige ARNTL Antikörper) and CLOCK.

  5. Both clock- and feeding-dependent mechanisms regulate the daily accumulation of key enzymes in polyamine biosynthesis through rhythmic binding of BMAL1 (zeige ARNTL Antikörper):CLOCK to conserved DNA elements

  6. RNA interference screens reveal the heterodimeric, circadian rhythm Transcription factors Clock and Bmal1 (zeige ARNTL Antikörper) as genes required for the growth of acute myeloid leukemia (zeige BCL11A Antikörper) cells in vitro and in vivo.

  7. Findings indicate that CLOCK protein (zeige ARNTL Antikörper) plays an important role in fertility and its knockdown leads to reduction in reproduction and increased miscarriage risk.

  8. Irp2 (zeige IREB2 Antikörper) mRNA transcription is promoted by circadian clock genes, including BMAL1 (zeige ARNTL Antikörper), and the CLOCK heterodimer.

  9. In CLOCK-deficient fibroblasts, knockdown of Npas2 (zeige NPAS2 Antikörper) leads to arrhythmicity, suggesting that NPAS2 (zeige NPAS2 Antikörper) can compensate for loss of CLOCK in peripheral cells as well as in suprachiasmatic nucleus.

  10. SERPINA3K is involved in the Clock gene-mediated male fertility by regulating acrosin (zeige ACR Antikörper) activity and provide the first evidence that SERPINA3K could be regulated by Clock gene via retinoic acid-related orphan receptor (zeige NR1D2 Antikörper) response elements.

Human Clock Homolog (Mouse) (CLOCK) Interaktionspartner

  1. Clock circadian regulator (CLOCK) gene single nucleotide polymorphism rs1801260 minor allele C showed a significantly higher association with the prevalence of diabetes in the Japanese population independent of body mass index (BMI).

  2. Immunostaining of CLOCK and PER2 (zeige PER2 Antikörper) protein was detected in the granulosa cells of dominant antral follicles but was absent in the primordial, primary, or preantral follicles of human ovaries.Oscillating expression of the circadian gene PER2 (zeige PER2 Antikörper) can be induced by testosterone in human granulosa cells in vitro. Expression of STAR also displayed an oscillating pattern after testosterone stimulation

  3. possible circadian rhythm in full-term placental expression

  4. Findings indicate that CLOCK protein (zeige ARNTL Antikörper) plays an important role in fertility and its knockdown leads to reduction in reproduction and increased miscarriage risk.

  5. Upregulation of CLOCK is associated with the expression of HIF-1alpha and VEGF in varicose veins.

  6. when overexpressed, c-MYC (zeige MYC Antikörper) is able to repress Per1 (zeige PER1 Antikörper) transactivation by BMAL1 (zeige ARNTL Antikörper)/CLOCK via targeting selective E-box sequences. Importantly, upon serum stimulation, MYC (zeige MYC Antikörper) was detected in BMAL1 (zeige ARNTL Antikörper) protein complexes

  7. CLOCK, ARNTL (zeige ARNTL Antikörper), and NPAS2 (zeige NPAS2 Antikörper) gene polymorphisms may have a role in seasonal variations in mood and behavior

  8. minor polymorphisms of CLOCK may be associated with poor morning gastric motility, and may have a combinatorial effect with PER3.

  9. these findings suggest that sumoylation plays a critical role in the spatiotemporal co-activation of CLOCK-BMAL1 (zeige ARNTL Antikörper) by CBP (zeige CREBBP Antikörper) for immediate-early (zeige JUN Antikörper) Per induction and the resetting of the circadian clock.

  10. the circadian gene hClock promoted CRC (zeige CALR Antikörper) progression and inhibit tumor cell apoptosis in vitro and in vivo, while silencing hClock was able to reverse this effect.

Xenopus laevis Clock Homolog (Mouse) (CLOCK) Interaktionspartner

  1. the second half of the photolyase homology region (PHR) of CRY (zeige CRY2 Antikörper) is important for repression through facilitating interaction with CLOCK

CLOCK Antigen-Profil

Beschreibung des Gens

This gene product regulates circadian rhythm and metabolism. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and a DNA binding histone acetyltransferase. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with CLOCK

  • Clock (Clk) Antikörper
  • clock homolog (mouse) (CLOCK) Antikörper
  • clock circadian regulator (clock) Antikörper
  • clock homolog (CLOCK) Antikörper
  • clock (clock) Antikörper
  • circadian locomotor output cycles kaput (Clock) Antikörper
  • clock circadian regulator (Clock) Antikörper
  • clock circadian regulator (CLOCK) Antikörper
  • 5330400M04Rik Antikörper
  • bHLHe8 Antikörper
  • bHLHe10 Antikörper
  • CG7391 Antikörper
  • clk Antikörper
  • clock Antikörper
  • dClck Antikörper
  • dclk Antikörper
  • dCLK/JRK Antikörper
  • dClock Antikörper
  • Dmel\\CG7391 Antikörper
  • Jerk Antikörper
  • jrk Antikörper
  • KAT13D Antikörper
  • mKIAA0334 Antikörper
  • PAS1 Antikörper
  • Xclk Antikörper
  • XClock Antikörper
  • zCLOCK1 Antikörper
  • zfCLOCK1 Antikörper

Bezeichner auf Proteinebene für CLOCK

CG7391-PA , CG7391-PD , CG7391-PF , CG7391-PG , CG7391-PH , CLOCK , Clk-PA , Clk-PD , Clk-PF , Clk-PG , Clk-PH , clock , dClock , clock homolog (mouse) , clock homolog , circadian locomoter output cycles protein kaput , circadian locomoter output cycles protein kaput-like , Clock1a , clk1 , circadian locomoter output cycles kaput , mCLOCK , rCLOCK , circadian locomoter output cycles kaput protein , class E basic helix-loop-helix protein 8 , circadian rhythmicity protein CLOCK

GENE ID SPEZIES
38872 Drosophila melanogaster
461312 Pan troglodytes
475145 Canis lupus familiaris
786637 Bos taurus
100008576 Meleagris gallopavo
100017022 Monodelphis domestica
100034166 Equus caballus
100038163 Xenopus (Silurana) tropicalis
100171391 Ovis aries
100172630 Pongo abelii
100349684 Oryctolagus cuniculus
100407407 Callithrix jacchus
30140 Danio rerio
100606130 Nomascus leucogenys
100628097 Sus scrofa
12753 Mus musculus
60447 Rattus norvegicus
9575 Homo sapiens
399157 Xenopus laevis
373991 Gallus gallus
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