Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) SPTBN1 Antikörper:
anti-Human SPTBN1 Antikörper:
anti-Rat (Rattus) SPTBN1 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Dog (Canine) Monoclonal SPTBN1 Primary Antibody für IF, WB - ABIN968883
Hu, Watanabe, Bennett: Characterization of human brain cDNA encoding the general isoform of beta-spectrin. in The Journal of biological chemistry 1992
Show all 3 Pubmed References
Dog (Canine) Monoclonal SPTBN1 Primary Antibody für IF, WB - ABIN968882
Moon, McMahon: Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin. in The Journal of biological chemistry 1990
Show all 3 Pubmed References
Human Polyclonal SPTBN1 Primary Antibody für ICC, IF - ABIN251513
Salcedo-Sicilia, Granell, Jovic, Sicart, Mato, Johannes, Balla, Egea: βIII spectrin regulates the structural integrity and the secretory protein transport of the Golgi complex. in The Journal of biological chemistry 2013
The findings showed that beta-2 spectrin plays a crucial role in hepatocyte proliferation, which contributes to liver regeneration. PI3K/Akt was involved in TGFbeta/Smad signalling pathway through the interaction with Smad proteins and beta-2 spectrin.
These data reveal that embryonic liver fodrin is involved in hepatic stellate cell activation and the formation of regenerative nodules derived from hepatic progenitor cells in cirrhotic liver.
Results of this study provide evidence for a role for spectrin in different steps of megakaryocyte development through its participation in the formation of invaginated membranes and in the maintenance of proplatelet structure.
costamere-association of dynactin-4 did not require dystrophin but did depend on beta2 spectrin and ankyrin-B, whereas costamere association of ankyrin-B required beta2 spectrin
ELF is involved in the pathogenesis of primary biliary cirrhosis and hepatocellular carcinoma.
Data show that Spnb2 [beta2SP(+/-)] mice are born with many phenotypic characteristics observed in BW (zeige CDKN1C Antikörper)S patients, suggesting that beta2SP mutant mice phenocopy BWS, and beta2SP loss could be one of the mechanisms associated with BWS.
downregulated expression in T cells following treatment with bis (zeige BAG3 Antikörper)(tri (zeige VANGL2 Antikörper)-n-butylin)oxide (TBTO), an immunotoxic organotin
results point to ELF as an essential adaptor protein required for key events in the propagation of TGF-beta (zeige TGFB1 Antikörper) signaling
interaction between members of the ankyrin and beta-spectrin families previously established in erythrocytes and axon initial segments also occurs in neonatal cardiomyocytes with ankyrin-B and beta(2)-spectrin.
In response to ELF deficiency, the abnormalities of G1/S checkpoint and senescence contribute their increment of susceptibility to malignant transformation.
c-Met overexpression, HER-2 (zeige ERBB2 Antikörper) gene amplification, and SPTBN1-ALK (zeige ALK Antikörper) gene fusion can coexist in lung adenocarcinoma and may become a potential biomarker of cancer refractory to crizotinib, chemotherapy, and radiotherapy as well as of a relatively poor prognosis.
Subjects whose head and neck tumors expressed spectrin were 4.60 times more likely (hazard ratio; 95% confidence interval: 1.88-11.25) to die at any given time when compared with those without spectrin (P = .001).
TGF-beta1 (zeige TGFB1 Antikörper) and ELF protein are potential and reliable biomarkers for predicting prognosis in HCC (zeige FAM126A Antikörper) patients after hepatic resection.
betaII spectrin is critical for normal myocyte electric activity. Dysfunction in the betaII spectrin-dependent cytoskeleton in cardiomyocytes contributes to human arrhythmia.
decreased SPTBN1 and kallistatin (zeige SERPINA4 Antikörper) gene expression associated with decreased relapse-free survival in hepatocellular carcinoma
in human HCC (zeige FAM126A Antikörper) tissues, SPTBN1 expression correlated negatively with expression levels of STAT3 (zeige STAT3 Antikörper), ATF3 (zeige ATF3 Antikörper), and CREB2 (zeige ATF4 Antikörper); SMAD3 (zeige SMAD3 Antikörper) expression correlated negatively with STAT3 (zeige STAT3 Antikörper) expression
genetic association study in population of 1,012 Han women in China: Data suggest that an SNP in SPTBN1 (rs11898505) is associated with osteoporotic fractures and bone mineral density of lumbar spine in aging women.
These results suggest that alpha-synuclein modulates neurite outgrowth by interacting with cytoskeletal proteins such as SPTBN1.
Results suggest that it is possible for cellular proteins to differentially associate with the C-termini of different beta-spectrin isoforms to regulate alpha- and beta-spectrin association to form functional spectrin tetramers.
Results suggest that epigenetic silencing of SPTBN1 (beta2SP) is a new potential causal factor in BWS (zeige CDKN1C Antikörper) patients.
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.
, beta-II spectrin
, beta-spectrin 2, non-erythrocytic
, brain spectrin
, embryonic liver fodrin
, fodrin beta chain
, spectrin G
, spectrin beta 2
, spectrin beta chain, brain 1
, spectrin beta chain, non-erythrocytic 1
, spectrin, non-erythroid beta chain 1
, beta-G spectrin
, beta-spectrin 2
, beta-spectrin II
, beta-spectrin non-erythrocytic 1
, embryonic liver beta-fodrin
, beta II spectrin-like (short form)
, cytoskeleton protein
, non-erythroid spectrin beta
, short form of beta II spectrin