anti-Slit Homolog 2 (Drosophila) (SLIT2) Antikörper

Bezeichnung:
anti-Slit Homolog 2 (Drosophila) Antikörper (SLIT2)
Auf www.antikoerper-online.de finden Sie aktuell 106 Slit Homolog 2 (Drosophila) (SLIT2) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Slit Homolog 2 (Drosophila) Kits (50) und Slit Homolog 2 (Drosophila) Proteine (23) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 181 Slit Homolog 2 (Drosophila) Produkte verfügbar.
Synonyme:
Drad-1, E030015M03Rik, E130320P19Rik, mKIAA4141, slil3, Slit, slit-2, SLIT2, slit2-a
Alle Antikörper anzeigen Gen GeneID UniProt
SLIT2 9353 O94813
SLIT2 20563 Q9R1B9
SLIT2 360272  

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Am meisten referenzierte anti-Slit Homolog 2 (Drosophila) Antikörper

  1. Human Polyclonal SLIT2 Primary Antibody für IHC, IHC (p) - ABIN4354558 : Yu, Cao, Yu, Wu, Dallol, Li, Chen, Grasso, Cao, Lonigro, Varambally, Mehra, Palanisamy, Wu, Latif, Chinnaiyan: The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer. in Oncogene 2010 (PubMed)
    Zeige alle 3 Referenzen für 4354558

  2. Human Polyclonal SLIT2 Primary Antibody für IHC (p), IHC - ABIN251500 : Lin, Rao, Isacson: Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. in Molecular and cellular neurosciences 2005 (PubMed)

Weitere Antikörper gegen Slit Homolog 2 (Drosophila) Interaktionspartner

Zebrafish Slit Homolog 2 (Drosophila) (SLIT2) Interaktionspartner

  1. These data supports a model whereby Wnt signaling through Frizzled-3a attenuates expression of Slit2 in the rostral midline of the forebrain.

  2. In embryonic axon tracts, Robo2 (zeige ROBO2 Antikörper) responds to signals from slit2 and slit3 (zeige SLIT3 Antikörper).

  3. Data show that Hedgehog (zeige SHH Antikörper) signaling is required for commissure formation, glial bridge formation, and the restricted expression of the guidance molecules slit1a, slit2, slit3 (zeige SLIT3 Antikörper) and sema3d (zeige SEMA3D Antikörper).

Xenopus laevis Slit Homolog 2 (Drosophila) (SLIT2) Interaktionspartner

  1. Slit acts via Robo2 (zeige ROBO2 Antikörper) in dendrites as a branching/growth factor but not in guidance, while Robo2 (zeige ROBO2 Antikörper) and Robo3 (zeige ROBO3 Antikörper) function in concert in axons to mediate axonal interactions and respond to Slits as guidance factors

Human Slit Homolog 2 (Drosophila) (SLIT2) Interaktionspartner

  1. human placental multipotent mesenchymal stromal cell express Slit2 (zeige SLIT3 Antikörper) and both Robo1 (zeige ROBO1 Antikörper) and Robo4 (zeige ROBO4 Antikörper) are present in human umbilical vein endothelial cells.

  2. Slit2 (zeige SLIT3 Antikörper)-Robo1 (zeige ROBO1 Antikörper) signaling promoted the adhesion, invasion and migration of tongue carcinoma cells by upregulating the expression levels of MMP2 (zeige MMP2 Antikörper) and MMP9 (zeige MMP9 Antikörper) and, downregulating the expression of E-cadherin (zeige CDH1 Antikörper).

  3. findings suggest that AK3 and SLIT2 may be potential candidates involved in genetic susceptibility to colorectal cancer

  4. Low Slit2 expression is associated with glioma.

  5. Results indicate the importance of SLIT2 (zeige SLIT3 Antikörper)-ROBO1 (zeige ROBO1 Antikörper)-CDC42 (zeige CDC42 Antikörper) signaling pathway in predicting tumor progression.

  6. We postulate that Robo1 (zeige ROBO1 Antikörper) promotes tumor invasion partly by the upregulation of MMP2 (zeige MMP2 Antikörper) after activation of PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling pathway. Notably, Slit2 (zeige SLIT3 Antikörper) knockdown caused the upregulation of Robo1 (zeige ROBO1 Antikörper) expression both at the mRNA and protein levels. Thus, the stimulatory effects of Slit2 (zeige SLIT3 Antikörper) knockdown on tumor progression can be ascribed, at least in part, to the upregulation of Robo1 (zeige ROBO1 Antikörper) and its positive role in tumor progression.

  7. expression of the evolutionarily conserved slit2 (zeige SLIT3 Antikörper) Gene Promoter Requires Sp1 (zeige PSG1 Antikörper)

  8. Study shows that Slit2 (zeige SLIT3 Antikörper) mRNA and protein levels were significantly reduced in papillary thyroid cancer (PTC (zeige F9 Antikörper)) specimens and implicates Slit2 (zeige SLIT3 Antikörper) functions as a negative regulator in the development and progression of PTC (zeige F9 Antikörper).

  9. Overexpression of Slit2 induces its tumor suppressive effects in Breast cancer.

  10. Significantly increased serum Slit2 (zeige SLIT3 Antikörper) levels and hepatic expression of Slit2 (zeige SLIT3 Antikörper) and Robo1 (zeige ROBO1 Antikörper) were observed in patients with liver fibrosis.

Mouse (Murine) Slit Homolog 2 (Drosophila) (SLIT2) Interaktionspartner

  1. While Slit1 (zeige SLIT1 Antikörper) and Robo2 (zeige ROBO2 Antikörper) are only expressed in peripheral axons and their cell bodies, Slit2, Slit3 (zeige SLIT3 Antikörper) and Robo1 (zeige ROBO1 Antikörper) are also expressed in satellite cells of the dorsal root ganglion, Schwann cells and fibroblasts of peripheral nerves.

  2. Transgenic over-expression of slit2 enhances disruption of blood-brain barrier and increases cell death after traumatic brain injury in mice. This suggest that over expression of slit2 plays a detrimental role in the pathophysiology of mild TBI.

  3. Slit2 induces a robust activation of PKA signaling, which is required for its prothermogenic activity.

  4. Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.

  5. Together, these observations suggest that Slit2 serves as a factor utilized by muscle Ctnnb1 (zeige CTNNB1 Antikörper) to direct presynaptic differentiation.

  6. Slit2 acts as a repellant cue to mediate axon guidance in the formation of the anterior commissure.

  7. Slit2/Robo1 (zeige ROBO1 Antikörper) signaling promotes intestinal tumorigenesis through Src (zeige SRC Antikörper)-mediated activation of the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway.

  8. the two genes neuropeptide Y (Npy (zeige NPY Antikörper)) and Slit homolog 2 (Drosophila) (Slit2) gradually increase during aging, and upon suppression of these two genes

  9. Data shows that modulation of angiostatic factor Slit2 by EphA2 receptor regulates endothelial responses to VEGF-mediated angiogenesis and tumor neovascularization.

  10. administration of Slit2 to atherosclerosis-prone LDL receptor (zeige LDLR Antikörper)-deficient mice inhibited monocyte recruitment to nascent atherosclerotic lesions.

Slit Homolog 2 (Drosophila) (SLIT2) Antigen-Profil

Beschreibung des Gens

acts as a ligand for glypican-1, a heparan sulfate proteoglycan\; may play a role in neurogenesis and midline development

Alternative names and synonyms associated with Slit Homolog 2 (Drosophila) (SLIT2)

  • slit homolog 2 (Drosophila) (SLIT2) Antikörper
  • slit homolog 2 (Drosophila) (Slit2) Antikörper
  • slit (Drosophila) homolog 2 (slit2) Antikörper
  • slit homolog 2 (slit2) Antikörper
  • slit homolog 2 (SLIT2) Antikörper
  • Drad-1 Antikörper
  • E030015M03Rik Antikörper
  • E130320P19Rik Antikörper
  • mKIAA4141 Antikörper
  • slil3 Antikörper
  • Slit Antikörper
  • slit-2 Antikörper
  • SLIT2 Antikörper
  • slit2-a Antikörper

Bezeichner auf Proteinebene für SLIT2

slit homolog 2 protein , downregulated during adipocyte differentiation-1 , neurogenic extracellular slit protein , slit-2 , slit homolog 2 (Drosophila)

GENE ID SPEZIES
9353 Homo sapiens
20563 Mus musculus
80353 Danio rerio
360272 Rattus norvegicus
373967 Gallus gallus
394404 Xenopus laevis
461137 Pan troglodytes
534164 Bos taurus
595148 Canis lupus familiaris
715470 Macaca mulatta
100348211 Oryctolagus cuniculus
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