anti-BLK (BLK) Antikörper

Bezeichnung:
anti-B Lymphoid Tyrosine Kinase Antikörper (BLK)
Auf www.antikoerper-online.de finden Sie aktuell 185 B Lymphoid Tyrosine Kinase (BLK) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BLK Proteine (17) und BLK Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 220 BLK Produkte verfügbar.
Synonyme:
bltk, MODY11, si:dkey-33i22.2, zgc:136231

Meistgesuchte Reaktivitäten zu anti-BLK (BLK) Antikörper

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anti-Mouse (Murine) BLK Antikörper:

anti-Human BLK Antikörper:

anti-Rat (Rattus) BLK Antikörper:

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Am meisten referenzierte anti-BLK Antikörper

  1. Human Monoclonal BLK Primary Antibody für ICC, FACS - ABIN968983 : Yang, Ng, Zhao, Hirankarn, Lau, Mok, Chan, Wong, Lee, Mok, Wong, Avihingsanon, Lee, Ho, Lee, Wong, Lau: Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese. in Genes and immunity 2009 (PubMed)
    Zeige alle 3 Referenzen für 968983

  2. Mouse (Murine) Polyclonal BLK Primary Antibody für WB - ABIN222964 : Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007 (PubMed)
    Zeige alle 2 Referenzen für 222964

  3. Human Polyclonal BLK Primary Antibody für IHC (p), WB - ABIN392087 : Islam, Rabbani, Larsson, Sanders, Smith: Molecular cloning, characterization, and chromosomal localization of a human lymphoid tyrosine kinase related to murine Blk. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Zeige alle 2 Referenzen für 392087

  4. Human Polyclonal BLK Primary Antibody für IHC, ELISA - ABIN1450638 : Drebin, Hartzell, Griffin, Campbell, Niederhuber: Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk). in Oncogene 1995 (PubMed)
    Zeige alle 2 Referenzen für 1450638

  5. Human Monoclonal BLK Primary Antibody für IHC, ELISA - ABIN968980 : Tretter, Ross, Dordai, Desiderio: Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk. in The Journal of experimental medicine 2003 (PubMed)

  6. Cow (Bovine) Polyclonal BLK Primary Antibody für WB - ABIN2782461 : Cho, Akbarali, Zerbini, Gu, Boltax, Wang, Oettgen, Zhang, Libermann: Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen BLK Interaktionspartner

Mouse (Murine) B Lymphoid Tyrosine Kinase (BLK) Interaktionspartner

  1. our study reveals a previously unappreciated role of reduced BLK (zeige BIK Antikörper) expression on extraperitoneal accumulation of B1a cells in mice, as well as the presence of IgG autoantibodies and B1-like cells in humans.

  2. BLK (zeige BIK Antikörper) risk alleles confer susceptibility to systemic lupus erythematosus through the dysregulation of a proinflammatory cytokine network.

  3. this study has revealed a previously unappreciated role for Blk (zeige BIK Antikörper) in the development and activation of MZ B cells

  4. BCR-ABL (zeige ABL1 Antikörper) downregulates the Blk (zeige BIK Antikörper) gene (encoding B-lymphoid kinase) through c-Myc (zeige MYC Antikörper) in leukemic stem cells in chronic myeloid leukemia (zeige BCL11A Antikörper)

  5. Data suggest a role of tyrosine kinase (zeige TYRO3 Antikörper) Btk (zeige BTK Antikörper) in the regulation of immune cell unctions and innate inflammatory response.

  6. Analysis of Blk (zeige BIK Antikörper)-deficient mice reveals that Blk (zeige BIK Antikörper) is required for the development of IL-17 (zeige IL17A Antikörper)-producing gammadelta T cell effectors and plays a role in regulating thymus cellularity during ontogeny.

  7. sustained activation of Blk (zeige BIK Antikörper) induces responses normally associated with the pre-BCR (zeige BCR Antikörper).

  8. Blk (zeige BIK Antikörper), being exceptionally highly expressed in the initial segment, is suggested to have a role in the differentiation of this segment of the epididymis.

Human B Lymphoid Tyrosine Kinase (BLK) Interaktionspartner

  1. ur study provides evidence that human BLK is a true proto-oncogene (zeige RAB1A Antikörper) capable of inducing tumors, and we demonstrate a novel BLK activity-dependent tumor model suitable for studies of BLK-driven lymphomagenesis and screening of novel BLK inhibitors in vivo.

  2. rs13277113 GA genotype of BLK is more frequent in Systemic Lupus Erythematosus patients and may have a role in low gene expression and increased flares

  3. current meta-analysis suggested that FAM167A-BLK rs2736340 polymorphism is associated with several autoimmune diseases

  4. the SNPs in TNFSF4 and FAM167A-BLK may be involved in asthma and allergic rhinitis gene risk in the Han Chinese cohort.

  5. The systemic lupus erythematosus variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 (zeige BANK1 Antikörper) through impairment of the SH3 domain (zeige ITSN1 Antikörper) function.

  6. Report a novel BLK gene variant in common variable immunodeficiency-patients that causes suppressed B-cell proliferation and reduced ability of B-cells to elicit antigen-specific CD4 (zeige CD4 Antikörper)(+) T-cell responses.

  7. A major mechanism underlying the BLK association with autoimmune disease involves lowered thresholds for basal B cell receptor signaling, enhanced B cell-T cell interactions, and altered patterns of isotype switching.

  8. our study reveals a previously unappreciated role of reduced BLK expression on extraperitoneal accumulation of B1a cells in mice, as well as the presence of IgG autoantibodies and B1-like cells in humans.

  9. Results support previous findings that vaiants in the RHOB and FAM167A-BLK genes may be associated with susceptibility to systemic sclerosis.

  10. These results place Blk upstream of the p190RhoGAP (zeige GRLF1 Antikörper)-RhoA (zeige RHOA Antikörper) pathway in Galpha13 (zeige GNA13 Antikörper)-activated cells, overall representing an opposing signaling module during CXCL12 (zeige CXCL12 Antikörper)-triggered invasion.

BLK Antigen-Profil

Beschreibung des Gens

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.

Alternative names and synonyms associated with BLK

  • B lymphoid tyrosine kinase (blk) Antikörper
  • B lymphoid tyrosine kinase (BLK) Antikörper
  • B lymphoid kinase (Blk) Antikörper
  • B lymphoid tyrosine kinase (Blk) Antikörper
  • bltk Antikörper
  • MODY11 Antikörper
  • si:dkey-33i22.2 Antikörper
  • zgc:136231 Antikörper

Bezeichner auf Proteinebene für BLK

B lymphoid kinase , tyrosine-protein kinase Blk , B lymphoid tyrosine kinase , tyrosine-protein kinase Blk-like , b lymphocyte kinase , p55-Blk , BLK nonreceptor tyrosine kinase

GENE ID SPEZIES
567764 Danio rerio
100412187 Callithrix jacchus
100442545 Pongo abelii
100479355 Ailuropoda melanoleuca
100559493 Anolis carolinensis
100601418 Nomascus leucogenys
12143 Mus musculus
640 Homo sapiens
486080 Canis lupus familiaris
532587 Bos taurus
364403 Rattus norvegicus
422035 Gallus gallus
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