Raptor Proteine (RPTOR)

Bezeichnung:
Regulatory Associated Protein of MTOR, Complex 1 Proteine (RPTOR)
Auf www.antikoerper-online.de finden Sie aktuell 3 Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Raptor Antikörper (82) und Raptor Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 95 Raptor Produkte verfügbar.
Synonyme:
4320, 4932417H02Rik, CG4320, DDBDRAFT_0191024, DDBDRAFT_0234064, DDB_0191024, DDB_0234064, Dmel\\CG4320, dRap, dRaptor, KOG1, Mip1, mKIAA1303, Rap, raptor, raptor/CG4320, RGD1311784
alle Proteine anzeigen Gen GeneID UniProt
Ratte RPTOR RPTOR 287871  
RPTOR 57521 Q8N122
RPTOR 74370  

Weitere Synonyme anzeigen

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Weitere Proteine zu Raptor Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) Interaktionspartner

  1. We found that neither S6K-dependent cell growth nor S6K-Thr-398 phosphorylation was affected in rictor-null mutants.

Human Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) Interaktionspartner

  1. Data show that mTOR (zeige FRAP1 Proteine) protein forms a complex with Raptor and estrogen receptor-alpha (ERalpha (zeige ESR1 Proteine)).

  2. Up-regulation of mTORC1 via raptor by aldosterone is a critical pathobiologic mechanism that controls pulmonary artery smooth muscle cell survival to promote hypertrophic vascular remodeling and pulmonary arterial hypertension.

  3. Hgh mTOR (zeige FRAP1 Proteine) activity and Rictor overexpression could be markers of a bad prognosis. Combined phosphoprotein and Rictor/Raptor expression evaluation revealed even stronger statistical correlation with prognosis.

  4. revealed more than 170 NFAT (zeige NFATC1 Proteine)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (zeige NFATC1 Proteine) and NFATc2 (zeige NFAT1 Proteine) in T cells, such as Raptor, CHEK1 (zeige CHEK1 Proteine), CREB1 (zeige CREB1 Proteine), RUNX1 (zeige RUNX1 Proteine), SATB1 (zeige SATB1 Proteine), Ikaros (zeige IKZF1 Proteine), and Helios (zeige ZNFN1A2 Proteine).

  5. In this study we began by validating the expression of four main mTOR (zeige FRAP1 Proteine) pathway components, mTOR (zeige FRAP1 Proteine), DEPTOR (zeige DEPTOR Proteine), rictor and raptor, at gene and protein level in in vitro models of endometrioid (MDAH2774) and clear cell (SKOV3) ovarian cancer

  6. Our results demonstrate for the first time that the expression quantitative trait loci of RPTOR, rs7502563, is susceptible to glioma

  7. The positive regulation of mTORC1 activity by NPRL2 (zeige NPRL2 Proteine) is mediated through NPRL2 (zeige NPRL2 Proteine) interaction with Raptor.

  8. Propose regulation of placental SNAT2 (zeige SLC38A2 Proteine)/LAT1 (zeige LAT Proteine) ubiquitination by mTORC1 and Nedd4-2 (zeige NEDD4L Proteine).

  9. RPTOR was not associated with bipolar disorder or schizophrenia.

  10. microRNA-210 and raptor are involved in mithramycin-mediated erythroid differentiation of K562 cells and participate to the fine-tuning and control of gamma-globin gene expression in erythroid precursor cells.

Mouse (Murine) Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) Interaktionspartner

  1. mitochondrial dysfunction triggers LKB1 (zeige STK11 Proteine)-mediated AMPK (zeige PRKAA1 Proteine) activation, which stimulates Sirt2 (zeige SIRT2 Proteine) phosphorylation, leading to activation of mTOR (zeige FRAP1 Proteine)-RAPTOR and Glut1 (zeige SLC2A1 Proteine)-mediated glucose uptake.

  2. inhibiting regulatory-associated protein of mechanistic target of rapamycin (zeige FRAP1 Proteine) (RPTOR) in hyperoxia settings, limited lung injury by increased autophagy, decreased apoptosis, improved lung architecture, and increased survival.

  3. Raptor knockout mice are lean and insulin (zeige INS Proteine) resistant with increased energy expenditure, and they are resistant to a high-fat diet.

  4. The findings reveal HDAC5 (zeige HDAC5 Proteine)-mTORC1 signaling as a novel mechanism in the differential regulation of gastric ghrelin (zeige GHRL Proteine) and nesfatin-1 (zeige NUCB2 Proteine).

  5. data suggest that EtOH-induced decreases in protein synthesis in fasted mice may be independent of mTORC1 and MAPK (zeige MAPK1 Proteine) signaling.

  6. Raptor negatively regulates hepatic Akt (zeige AKT1 Proteine) activity and lipogenesis via PHLPP2 (zeige PHLPP2 Proteine) stabilization.

  7. mTOR (zeige FRAP1 Proteine) kinase-dependent, but raptor-independent regulation of downstream signaling is important for myogenic differentiation.

  8. conditional gene ablation of raptor causes delayed myelination initiation as well as hypomyelination, together with abnormal lipid composition and decreased nerve conduction velocity.

  9. Rptor deficiency/mTORC1 Signaling in oocytes are dispensable for the survival of primordial follicles and for female fertility.

  10. Raptor ablation in skeletal muscle decreases Cav1.1 (zeige CACNA1S Proteine) expression and affects the function of the excitation-contraction coupling supramolecular complex.

Raptor (RPTOR) Protein Überblick

Protein Überblick

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Raptor (RPTOR)

  • CG4320 gene product from transcript CG4320-RB (raptor)
  • regulatory associated protein of MTOR, complex 1 (Rptor)
  • regulatory associated protein of MTOR, complex 1 (RPTOR)
  • regulatory associated protein of MTOR, complex 1 (rptor)
  • HEAT repeat-containing protein (raptor)
  • 4320 Protein
  • 4932417H02Rik Protein
  • CG4320 Protein
  • DDBDRAFT_0191024 Protein
  • DDBDRAFT_0234064 Protein
  • DDB_0191024 Protein
  • DDB_0234064 Protein
  • Dmel\\CG4320 Protein
  • dRap Protein
  • dRaptor Protein
  • KOG1 Protein
  • Mip1 Protein
  • mKIAA1303 Protein
  • Rap Protein
  • raptor Protein
  • raptor/CG4320 Protein
  • RGD1311784 Protein

Bezeichner auf Proteinebene für RPTOR

CG4320-PB , dRaptor , raptor-PB , target of rapamycin (TOR)-associated protein , raptor , Raptor family protein , WD40 repeat-containing protein , armadillo-like helical domain-containing protein , p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats , regulatory-associated protein of mTOR , p150 target of rapamycin (TOR)-scaffold protein

GENE ID SPEZIES
31543 Drosophila melanogaster
287871 Rattus norvegicus
454949 Pan troglodytes
495002 Xenopus laevis
8617737 Dictyostelium discoideum AX4
100170605 Xenopus (Silurana) tropicalis
57521 Homo sapiens
74370 Mus musculus
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