anti-PPP2R4 (PPP2R4) Antikörper

anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 Antikörper (PPP2R4)
Auf finden Sie aktuell 69 Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PPP2R4 Proteine (9) und PPP2R4 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 92 PPP2R4 Produkte verfügbar.
2610042B21Rik, 6330556D22Rik, C77440, N28142, PP2A, PR53, PR65, PTPA, PTPRA
Alle Antikörper anzeigen Gen GeneID UniProt
PPP2R4 51792 Q76MZ3
PPP2R4 5524 Q15257

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Meistgesuchte Reaktivitäten zu anti-PPP2R4 (PPP2R4) Antikörper

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anti-Mouse (Murine) PPP2R4 Antikörper:

anti-Human PPP2R4 Antikörper:

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Am meisten referenzierte anti-PPP2R4 Antikörper

  1. Human Monoclonal PPP2R4 Primary Antibody für ICC, FACS - ABIN969557 : Yoon, Jun, Park, Jun Yoo, Moon, Soon Baik, Kim, Kim, Kim, Koh, Taek Lee, You: Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal. in Stem cells (Dayton, Ohio) 2010 (PubMed)
    Zeige alle 2 Referenzen für 969557

  2. Human Monoclonal PPP2R4 Primary Antibody für EIA, FACS - ABIN1108715 : Singh, Ye, Bucur, Zhu, Tanya Santos, Rabinovitz, Wei, Gao, Hahn, Khosravi-Far: Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. in Molecular biology of the cell 2010 (PubMed)
    Zeige alle 2 Referenzen für 1108715

  3. Human Polyclonal PPP2R4 Primary Antibody für ChIP, WB - ABIN2668597 : Fellner, Lackner, Hombauer, Piribauer, Mudrak, Zaragoza, Juno, Ogris: A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. in Genes & development 2003 (PubMed)

  4. Human Polyclonal PPP2R4 Primary Antibody für ELISA, WB - ABIN4347103 : Gushiken, Patel, Liu, Pradhan, Bergeron, Peng, Vijayan: Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen PPP2R4 Interaktionspartner

Mouse (Murine) Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Interaktionspartner

  1. data indicate that PTPalpha (zeige PTPRA Antikörper) and FAK (zeige PTK2 Antikörper), which are enriched in FAs (zeige FAS Antikörper), interact with IP3R1 (zeige ITPR1 Antikörper) at adjacent ER sites to spatially sequester IL-1 (zeige IL1A Antikörper)-induced Ca(2 (zeige CA2 Antikörper)+) signalling

  2. oocyte-specific deletion of Ppp2r1a (zeige PPP2R1A Antikörper) led to severe female subfertility without affecting follicle survival, growth, and ovulation.

  3. A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

  4. PP2A (zeige PPP2R2B Antikörper) (Protein Phosphatase 2A(Twins)) counteracts Plk4 (zeige PLK4 Antikörper) autophosphorylation, thus stabilizing Plk4 (zeige PLK4 Antikörper) and promoting centriole duplication

  5. PP2A (zeige PPP2R2B Antikörper)-A alpha transcriptional regulation is mediated by multiple factors including AP-2alpha (zeige TFAP2A Antikörper), CREB (zeige CREB1 Antikörper), ETS-1 (zeige ETS1 Antikörper), and SP-1 (zeige SP1 Antikörper)

  6. Data show that DSB promote PP2A to associate with Ku 70 and Ku 86.

  7. protein phosphatase 2A overexpression in NIH 3T3 cells

  8. T-cell receptor (TCR)-dependent tyrosine phosphorylation may be the mechanism by which the regulatory subunit of PP2A (zeige PPP2R2B Antikörper) prevents the inhibitory function of CTLA-4 (zeige CTLA4 Antikörper), before TCR-CTLA-4 (zeige CTLA4 Antikörper) coligation.

  9. PP-2A regulation of paxillin (zeige PXN Antikörper) phosphorylation may have a role in controlling tumor cell adherence and motility.

  10. PP2A (zeige PPP2R2B Antikörper) may contribute to melanoma cell radioresistance: the truncated isoform of the PP2A (zeige PPP2R2B Antikörper) B56gamma regulatory subunit reduces irradiation-induced Mdm2 (zeige MDM2 Antikörper) phosphorylation

Human Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Interaktionspartner

  1. The results of this study demonstrated that HBx of hepatitis B virus impairs interferon (zeige IFNA Antikörper) signaling via increased expression of SOCS3 (zeige SOCS3 Antikörper) and PP2A.

  2. The current study describes a novel pathogenic mechanism of action for human polyomavirus 6 small tumor (sT) antigen which involves binding to protein phosphatase 2A (PP2A) via its WFG motif and zinc binding sites for activation of PP2A's downstream oncogenic pathways (MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper)/c-Jun (zeige JUN Antikörper)).

  3. The aim of this review is to shed light on the role of four different phosphatases (PTEN (zeige PTEN Antikörper), PP2A, CDC25 (zeige RASGRF1 Antikörper) and DUSP1 (zeige DUSP1 Antikörper)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  4. Oncoprotein CIP2A (zeige KIAA1524 Antikörper) is stabilized via interaction with tumor suppressor PP2A/B56

  5. Such effect by miR (zeige MLXIP Antikörper)-429 was again abolished with AMPKalpha1 (zeige PRKAA1 Antikörper) silence or mutation. Together, we propose that PP2A-c silence by miR (zeige MLXIP Antikörper)-429 activates AMPK (zeige PRKAA1 Antikörper) and protects osteoblastic cells from Dex.

  6. PTPalpha (zeige PTPRA Antikörper) is identified as a novel substrate of N-Acetylglucosaminyltransferase V (GnT-V (zeige MGAT5 Antikörper)) and could be a factor regulating promotion of migration in breast cancer cells

  7. This article reviews the involvement of PP2A in the regulation of three cell signaling pathways: wnt (zeige WNT2 Antikörper), mTOR (zeige FRAP1 Antikörper) and MAP kinase (zeige MAPK1 Antikörper), as well as the G1-->S transition, DNA synthesis and mitotic initiation. These processes are all crucial for proper cell survival and proliferation and are often deregulated in cancer and other diseases. [review]

  8. PP2A-B55 (zeige MINK1 Antikörper) substrates were identified and assigned their temporal order in mitotic exit.

  9. Our results provide a novel mechanistic insight into the activation of Myc (zeige MYC Antikörper) by 27-HC via transcriptional repression of PP2A, SCP1 (zeige SYCP1 Antikörper) and FBW7 (zeige FBXW7 Antikörper) to increase Myc (zeige MYC Antikörper) protein stability in breast cancer cells.

  10. Data show that the truncation promotes glycogen synthase kinase-3beta (GSK-3beta (zeige GSK3b Antikörper)) nuclear translocation and enhances its interaction with protein phosphatase 2A (PP2A), leading to dephosphorylation.

PPP2R4 Antigen-Profil

Beschreibung des Gens

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PPP2R4

  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a) Antikörper
  • protein phosphatase 2A activator, regulatory subunit 4 (PPP2R4) Antikörper
  • protein phosphatase 2A, regulatory subunit B (PR 53) (Ppp2r4) Antikörper
  • 2610042B21Rik Antikörper
  • 6330556D22Rik Antikörper
  • C77440 Antikörper
  • N28142 Antikörper
  • PP2A Antikörper
  • PR53 Antikörper
  • PR65 Antikörper
  • PTPA Antikörper
  • PTPRA Antikörper

Bezeichner auf Proteinebene für PPP2R4

PP2A subunit A isoform PR65-alpha , PP2A subunit A isoform R1-alpha , protein phosphatase PP2A , serine/threonine protein phosphatase A subunit type 2A , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform , PP2A phosphatase activator , PP2A subunit B' isoform PR53 , phosphotyrosyl phosphatase activator , protein phosphatase 2A, regulatory subunit B' (PR 53) , serine/threonine-protein phosphatase 2A activator , serine/threonine-protein phosphatase 2A regulatory subunit B' , PP2A, subunit B', PR53 isoform , PTPA , serine/threonine-protein phosphatase 2A regulatory subunit 4 , protein tyrosine phosphatase, receptor type, A

51792 Mus musculus
5524 Homo sapiens
514460 Bos taurus
100009404 Oryctolagus cuniculus
110854 Mus musculus
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