FOXO1 Proteine (FOXO1)

Forkhead Box O1 Proteine (FOXO1)
Auf finden Sie aktuell 9 Forkhead Box O1 (FOXO1) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FOXO1 Antikörper (434) und FOXO1 Kits (57) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 521 FOXO1 Produkte verfügbar.
Afxh, AI876417, FKH1, Fkhr, Fkhr1, foxo1, FoxO1A, FoxO1a.1, xFoxO1, zgc:153388
alle Proteine anzeigen Gen GeneID UniProt
FOXO1 2308 Q12778
FOXO1 56458 Q9R1E0
Ratte FOXO1 FOXO1 84482  

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Weitere Proteine zu FOXO1 Interaktionspartnern

Cow (Bovine) Forkhead Box O1 (FOXO1) Interaktionspartner

  1. MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.

  2. downregulation of SIRT1 (zeige SIRT1 Proteine) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age

  3. FOXO (zeige FOXO3 Proteine) is a key regulator of ROS (zeige ROS1 Proteine)-induced apoptosis in mammalian cells.

  4. Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (zeige NCAM1 Proteine)-1 mRNA.

  5. The results demonstrate pathways through which two different mediators, TNF-alpha (zeige TNF Proteine) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.

Human Forkhead Box O1 (FOXO1) Interaktionspartner

  1. The FOXO1 serves a pivotal role in LEC migration toward exogenous ATP via direct transcriptional regulation of P2Y1 receptor (zeige P2RY1 Proteine).

  2. miR (zeige MLXIP Proteine)-615-3p negatively regulates the osteogenic differentiation of hLF (zeige EPAS1 Proteine) cells through post-transcriptionally suppressing osteogenic regulators GDF5 (zeige GDF5 Proteine) and FOXO1.

  3. our findings identify the TXN (zeige TXN Proteine)-FOXO1-p300 (zeige EP300 Proteine) circuit as the sensor and effector of oxidative stress in DLBCL cells

  4. Study confirmed that the crosstalk of esophageal squamous cell carcinoma (ESCC) cells and cancer-associated fibroblasts promoted the expression and activation of FOXO1, which then caused TGFb1 (zeige TGFB1 Proteine) expression in an autocrine/paracrine signaling loop resulting in ESCC chemoresistance.

  5. PAX3 (zeige PAX3 Proteine)-FOXO1 collaborates with MYCN (zeige MYCN Proteine) during early rhabdomyosarcoma (RMS) tumourigenesis to dysregulate proliferation and inhibit myogenic differentiation and cell death.

  6. Ik6, the upstream factor of Akt (zeige AKT1 Proteine)-FoxO1 pathway, can protect acute lymphoblastic leukemia cells against daunorubicin-induced apoptosis

  7. elevated serum and cellular levels of mTOR (zeige FRAP1 Proteine) in the IGT group and FOXO-1 in IFG (zeige IFNG Proteine) and IGT groups may be triggered by increased glucose concentration. Indeed, mTOR (zeige FRAP1 Proteine)-mediated variations in cellular level from female patients and FOXO-1-mediated variations of male patients indicated that these factors might play a critical role in glucose intolerance.

  8. This study provides new insights on the action of insulin (zeige INS Proteine) on the endometrium via regulation of FOXO1.

  9. the involvement of oxidative stress in the atrophy of COPD peripheral muscle cells in vitro, via the FoxO1/MuRF1/atrogin-1 signaling pathway of the ubiquitin/proteasome system

  10. elevated FOXO1 contributes to BCR (zeige BCR Proteine)-ABL1 (zeige ABL1 Proteine) kinase-independent resistance experienced by relapsed CML (zeige BCR Proteine) patients lacking BCR (zeige BCR Proteine)-ABL1 (zeige ABL1 Proteine) kinase domain mutations

Pig (Porcine) Forkhead Box O1 (FOXO1) Interaktionspartner

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.

  2. let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (zeige MAP3K1 Proteine) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.

  3. inhibition of FoxO1 expression level caused by miR (zeige MYLIP Proteine)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (zeige MYLIP Proteine)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1

  4. Results show that FoxO1 likely regulates MyHC I (zeige MYH7 Proteine) negatively and MyHC IIx and MyHC IIb (zeige MYH4 Proteine) positively and may play a pivotal role in the determination of muscle fiber type.

  5. Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (zeige TNFSF10 Proteine) and Fas ligand FasL (zeige FASL Proteine) expression during follicular atresia.

  6. Data show that IL-4 (zeige IL4 Proteine) induces upregulation of the junction protein claudin-5 (zeige CLDN5 Proteine) in endothelial cells (ECs) through activation of Jak (zeige JAK3 Proteine)/STAT6 (zeige STAT6 Proteine) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.

  7. FoxO1 and C/EBPb (zeige CEBPB Proteine) regulate preadipocyte adipogenesis possibly through C/EBPb (zeige CEBPB Proteine)-> FoxO1-> C/EBPb (zeige CEBPB Proteine) feedback regulatory loop and FoxO1-C/EBPb (zeige CEBPB Proteine) protein complex.

  8. FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.

  9. concluded that PI 3 (zeige PI3 Proteine)-kinase and Akt (zeige AKT1 Proteine) are activated after renal ischemia/reperfusion and that Akt (zeige AKT1 Proteine) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (zeige FOXO3 Proteine), which may affect epithelial cell fate in acute renal failure.

  10. FoxO1a can regulate p27kip nuclear localization

Mouse (Murine) Forkhead Box O1 (FOXO1) Interaktionspartner

  1. These results suggest that the LKB1 (zeige STK11 Proteine)-AMPK (zeige PRKAA1 Proteine)-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.

  2. These data strongly suggest that intestinal apoC-III (zeige APOC3 Proteine) is not a FoxO1 target and support the idea that apoC-III (zeige APOC3 Proteine) is not regulated coordinately with hepatic apoC-III (zeige APOC3 Proteine), and establishes another key aspect of apoC-III (zeige APOC3 Proteine) that is unique in the intestine from the liver.

  3. this study shows that miR (zeige MLXIP Proteine)-183C drives Th17 pathogenicity in experimental autoimmune encephalomyelitis via inhibition of Foxo1

  4. The findings of this study suggest that Foxo (zeige FOXO3 Proteine)-regulated pathways are downstream of Isl1 (zeige ISL1 Proteine) in the survival and/or differentiation of direct pathway striatal projection neurons.

  5. Endothelial FoxO (zeige FOXO3 Proteine) proteins promote insulin (zeige INS Proteine) resistance in HF diet, which may in part result from FoxO (zeige FOXO3 Proteine) proteins establishing an antiangiogenic and proinflammatory microenvironment within skeletal muscle. These findings provide mechanistic insight into the development of microvascular dysfunction in the progression of type 2 diabetes.-

  6. ablation of Foxo1 after Germinal center (GC) development led to the loss of the dark zone GC B (zeige NPR2 Proteine) cells and disruption of the GC architecture.

  7. Suppression of Sirt1 (zeige SIRT1 Proteine) or Foxo-1 expression significantly impaired exendin-4-induced adiponectin (zeige ADIPOQ Proteine) expression. Consistently, exendin-4 up-regulated Sirt1 (zeige SIRT1 Proteine) and Foxo-1 expression in vivo. Our work is the first study demonstrating the role of Sirt1 (zeige SIRT1 Proteine)/Foxo-1 in regulating the regulatory function of a GLP-1 receptor (zeige GLP1R Proteine) agonist in adiponectin (zeige ADIPOQ Proteine) expression both in vitro and in vivo.

  8. This study shows that TNF-alpha (zeige TNF Proteine), by a Foxo1 dependent pathway, increases the transcription of ANGPTL4 (zeige ANGPTL4 Proteine) which is secreted by the cells and causes inactivation of LPL (zeige LPL Proteine).

  9. JNK (zeige MAPK8 Proteine)/FoxO1 is involved in the regulation of oxidative stress-induced (zeige SQSTM1 Proteine) cell apoptosis in MGCs

  10. Increased Forkhead box protein 1 (FoxO1) acetylation and nuclear retention was followed by progressive FoxO1 loss in beta cells that marked the onset of diabetes.

Xenopus laevis Forkhead Box O1 (FOXO1) Interaktionspartner

  1. FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (zeige SOD1 Proteine) and catalase (zeige CAT Proteine) mRNA and protein levels in this organ.

Zebrafish Forkhead Box O1 (FOXO1) Interaktionspartner

  1. These results indicate that miR (zeige MYLIP Proteine)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.

  2. gas6 (zeige GAS6 Proteine) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (zeige AKT1 Proteine)-dependent inactivation of FOXO1a.

FOXO1 Protein Überblick

Protein Überblick

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Alternative names and synonyms associated with FOXO1

  • forkhead box O1 (FOXO1)
  • forkhead box O1 (foxo1)
  • forkhead box O1 (Foxo1)
  • forkhead box O1 a (foxo1a)
  • Afxh Protein
  • AI876417 Protein
  • FKH1 Protein
  • Fkhr Protein
  • Fkhr1 Protein
  • foxo1 Protein
  • FoxO1A Protein
  • FoxO1a.1 Protein
  • xFoxO1 Protein
  • zgc:153388 Protein

Bezeichner auf Proteinebene für Forkhead Box O1 Proteine (FOXO1)

forkhead box O1 , forkhead box O1A , forkhead box O1A (rhabdomyosarcoma) , forkhead box protein O1 , forkhead box protein O1-like , forkhead box protein O1A , forkhead, Drosophila, homolog of, in rhabdomyosarcoma , Forkhead box protein O1A , Forkhead in rhabdomyosarcoma , forkhead/winged helix transcription factor FOXO1a , forkhead in rhabdomyosarcoma , forkhead box O1a , forkhead protein 1 , xFoxO1 , forkhead box protein O1-A , fox family transcription factor FoxO1a.1 , foxhead box protein O1-A

100050481 Equus caballus
282234 Bos taurus
467352 Pan troglodytes
493378 Xenopus (Silurana) tropicalis
700030 Macaca mulatta
100460676 Pongo abelii
100594615 Nomascus leucogenys
2308 Homo sapiens
374231 Gallus gallus
397077 Sus scrofa
506618 Bos taurus
56458 Mus musculus
84482 Rattus norvegicus
444991 Xenopus laevis
477295 Canis lupus familiaris
101107877 Ovis aries
768121 Danio rerio
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