anti-Cyclin D1 (CCND1) Antikörper

Bezeichnung:
anti-Cyclin D1 Antikörper (CCND1)
Auf www.antikoerper-online.de finden Sie aktuell 540 Cyclin D1 (CCND1) Antikörper von 35 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Cyclin D1 Kits (54) und Cyclin D1 Proteine (27) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 648 Cyclin D1 Produkte verfügbar.
Synonyme:
AI327039, bcl-1, BCL1, cb161, CCND1, ccnd1a, ccnd1b, ccndbp1, cD1, cycd1, Cyl-1, D11S287E, etID37810.7, fb52e01, fc45c08, fc83a12, id:ibd1198, PRAD1, U21B31, wu:fb52e01, wu:fc45c08, wu:fc83a12, ZHM
Alle Antikörper anzeigen Gen GeneID UniProt
CCND1 595 P24385
CCND1 12443 P25322
Anti-Ratte CCND1 CCND1 58919 P39948

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Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Cyclin D1 Antikörper

  1. Human Polyclonal Cyclin D1 Primary Antibody für WB - ABIN389144 : He, Council, Feng, Chignell: UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes. in Cancer research 2008 (PubMed)
    Zeige alle 3 Referenzen für 389144

  2. Human Monoclonal Cyclin D1 Primary Antibody für FACS, IHC (p) - ABIN1106871 : Zou, Peng, Zhou, Wen, Wang, Tsai, Hung: Systemic tumor suppression by the proapoptotic gene bik. in Cancer research 2002 (PubMed)
    Zeige alle 3 Referenzen für 1106871

  3. Human Monoclonal Cyclin D1 Primary Antibody für IHC (fro), IF - ABIN1106872 : Rosenberg, Kim, Shows, Kronenberg, Arnold: Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors. in Oncogene 1991 (PubMed)
    Zeige alle 3 Referenzen für 1106872

  4. Human Polyclonal Cyclin D1 Primary Antibody für EIA, WB - ABIN357821 : Marsit, Black, Posner, Kelsey: A genotype-phenotype examination of cyclin D1 on risk and outcome of squamous cell carcinoma of the head and neck. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Zeige alle 3 Referenzen für 357821

  5. Human Polyclonal Cyclin D1 Primary Antibody für IF, IHC (p) - ABIN389146 : Caldon, Swarbrick, Lee, Sutherland, Musgrove: The helix-loop-helix protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini. in Cancer research 2008 (PubMed)
    Zeige alle 3 Referenzen für 389146

  6. Human Polyclonal Cyclin D1 Primary Antibody für IF, WB - ABIN651507 : Edel, Menchon, Menendez, Consiglio, Raya, Izpisua Belmonte: Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. in Genes & development 2010 (PubMed)
    Zeige alle 2 Referenzen für 651507

  7. Cow (Bovine) Polyclonal Cyclin D1 Primary Antibody für IHC, WB - ABIN2777893 : Kibel, Jin, Klim, Luly, A Roehl, Wu, Suarez: Association between polymorphisms in cell cycle genes and advanced prostate carcinoma. in The Prostate 2008 (PubMed)

Weitere Antikörper gegen Cyclin D1 Interaktionspartner

Xenopus laevis Cyclin D1 (CCND1) Interaktionspartner

  1. Results suggest that the TCF (zeige HNF4A Antikörper)/LEF signaling pathway participates in the regulation of cyclin D1 induction during the generation of the dorsal nervous system in early frog embryogenesis.

Zebrafish Cyclin D1 (CCND1) Interaktionspartner

  1. while cyclin B1 RNA granules were disassembled in a manner dependent on actin filament depolymerization, certain fractions of mos RNA granules were disassembled independently of actin filaments. These results suggest that cytoplasmic regulation of translationally repressed mRNAs by formation of different RNA granules is a key mechanism for translational control of

  2. Maid (zeige CCNDBP1 Antikörper) is important regulator of hepatocarcinogenesis and aging

  3. show that the knockdown of smc1a (zeige SMC1A Antikörper) in zebrafish impairs neural development, increases apoptosis, and specifically down-regulates Ccnd1 levels

  4. Reduction of cyclin D1 expression compromises zebrafish eye and head development.

  5. Role in cell cycle control is mediated by meis1 (zeige MEIS1 Antikörper) regulating cyclin D1 and c-myc (zeige MYC Antikörper) transcription in the embryonic eye.

Human Cyclin D1 (CCND1) Interaktionspartner

  1. majority (82%) of blue nevi stained negative for p16 (zeige CDKN2A Antikörper). There was not a significant difference between p16 (zeige CDKN2A Antikörper) staining in benign blue nevi and melanoma (P=0.06). Eleven (73%) melanomas stained positive for cyclin D1 with a sensitivity of 0.73 and positive predictive value of 1.0

  2. Cyclin D1 protein and mRNA expression levels were up-regulated by RhoA (zeige RHOA Antikörper) G14V, and these effects were inhibited by siRNA-mediated knock-down of PKN1 (zeige PKN1 Antikörper). The effect of RhoA (zeige RHOA Antikörper) on ESC proliferation is mediated by activation of the PKN1 (zeige PKN1 Antikörper)-cyclin D1 pathway in vitro

  3. Down-regulation of Mig-6 (zeige ERRFI1 Antikörper) induces Cyclin D1 expression and activates the MAPK-ERK (zeige MAPK1 Antikörper) signaling pathway.The overexpression of Mig-6 (zeige ERRFI1 Antikörper) led to significant G1 arrest and growth inhibition in hepatocellular carcinoma cells, possibly through the inhibition P-ERK (zeige EPHB2 Antikörper) and Cyclin D1.

  4. Two different mechanisms: acquired radioresistance of surviving tumor cells after RT and intrinsic radioresistance of CSC are associated with tumor radioresistance. Inhibition of the AKT (zeige AKT1 Antikörper) pathway results in radiosensitization of both types of tumor radioresistance. [review]

  5. NT3 (zeige NTF3 Antikörper) upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk (zeige NTRK1 Antikörper)-Akt (zeige AKT1 Antikörper)-cyclin D1 cascade.

  6. Noxin (zeige C11orf82 Antikörper) facilitated the expression of Cyclin D1 and Cyclin E1 (zeige CCNE1 Antikörper) through activating P38 (zeige CRK Antikörper)-activating transcription factor 2 (zeige ATF2 Antikörper) signaling pathway, thus enhanced cell growth of breast cancer

  7. Gains of CCND1 is associated with hypopharyngeal squamous cell carcinoma.

  8. Data suggest that CDK4 (cyclin-dependent kinase 4 (zeige CDK4 Antikörper)) is degraded by anaphase-promoting complex/cyclosome (APC (zeige APC Antikörper)/C) during metaphase-anaphase transition while its main regulator, cyclin D1, remains intact but is sequestered in cytoplasm; CDK4 (zeige CDK4 Antikörper) protein reaccumulates in the following G1 phase and shuttles between nucleus and cytoplasm to facilitate nuclear import of cyclin D1; without CDK4 (zeige CDK4 Antikörper), cyclin D1 cannot enter nucleus.

  9. The positive rates of MAPK (zeige MAPK1 Antikörper) and cyclin D1 in osteosarcoma were increased (P<0.05), and the expression of cyclin D1 and pMAPK were positively correlated. The phosphorylation of MAPK (zeige MAPK1 Antikörper) may be important in the development of osteosarcoma, and the overactivation of MAPK (zeige MAPK1 Antikörper) may induce high expression of cyclin D1 and induce tumor cells to proliferate continuously.

  10. Varying degrees of immunoreactivity to Cyclin D1, VEGF (zeige VEGFA Antikörper), and EZH2 (zeige EZH2 Antikörper) were noted in the majority of the AT/RTs (zeige RECQL4 Antikörper), and detection of these markers may be of value in the development of novel therapeutic agents and in determining which patients can benefit from them

Mouse (Murine) Cyclin D1 (CCND1) Interaktionspartner

  1. our results are consistent with an epithelial proliferative growth mechanism linking CTNNB1 (zeige CTNNB1 Antikörper)-driven Ccnd1 transcription and estrogen-mediated CCND1 protein stabilization.

  2. identify Pax5 (zeige PAX5 Antikörper) and cyclin D1 as Zfp521 (zeige ZNF521 Antikörper) target genes, and suggest that excessive B-cell proliferation observed in mice with retroviral insertions near the Zfp521 (zeige ZNF521 Antikörper) gene is due to an up-regulation of cyclin D1 in B-cells.

  3. Data show that expression of the Oct-4 (zeige POU5F1 Antikörper), Sox2 (zeige SOX2 Antikörper), Klf4 (zeige KLF4 Antikörper), and c-Myc (zeige MYC Antikörper) (OSKM) reprogramming factors induces Cyclin D1 expression, and the increased Cyclin D1 expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.

  4. study shows that PLCgamma1 (zeige PLCG1 Antikörper) controls osteoclast numbers via a CSF-1 (zeige CSF1 Antikörper)-dependent DAG/beta-catenin (zeige CTNNB1 Antikörper)/cyclinD1 pathway.

  5. Regarding extratelomeric activities, our results showed a decrease of 64, 38 and 25% in the transcription of c-Myc (zeige MYC Antikörper), Cyc (zeige CYCS Antikörper)-D1 and TERT (zeige TERT Antikörper), respectively (p<0.05) after AZT treatment. Furthermore, we found an effect on cell migration, reaching an inhibition of 48% (p<0.05) and a significant passage-dependent increase on cell doubling time during treatment.

  6. Using Ccnd1 knockout mice, the study shows that Ccnd1 expression significantly contributes to tumor incidence in teratoma (zeige DND1 Antikörper) susceptible mice without being necessary for normal germ cell or testis development.

  7. Ras (G12V)-induced cyclin D1 protein synthesis was markedly suppressed by the knockdown of IL-33 (zeige IL33 Antikörper).

  8. Novel RNA-binding activity of MYF5 (zeige MYF5 Antikörper) enhances Ccnd1 mRNA translation during myogenesis.

  9. The robust increase in the expression of cyclin D1 and CDK4 (zeige CDK4 Antikörper) at day 2 suggests that Muller glia may be in G1 phase of the cell cycle at this stage.

  10. Btg1 (zeige BTG1 Antikörper) regulates the proliferation of cerebellar granule precursors selectively through cyclin D1.

Cow (Bovine) Cyclin D1 (CCND1) Interaktionspartner

  1. cyclin D1, CDK2 (zeige CDK2 Antikörper) and CDK4 (zeige CDK4 Antikörper) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation

  2. 17beta-estradiol (E2) induces cell proliferation of bovine arterial endothelial cells through upregulation of cyclin D1 via non-genomic activation of the extracellular signal-regulated microtubule-associated Protein 2 kinase (ERK1 (zeige MAPK3 Antikörper) kinase) pathway.

Cyclin D1 (CCND1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Alternative names and synonyms associated with Cyclin D1 (CCND1)

  • cyclin D1 (ccnd1-b) Antikörper
  • cyclin D1 (ccnd1) Antikörper
  • Cyclin-D1-binding protein 1 homolog (ccndbp1) Antikörper
  • cyclin Dx (ccndx) Antikörper
  • zgc:162082 (zgc:162082) Antikörper
  • cyclin D1 (CCND1) Antikörper
  • G1/S-specific cyclin-D1 (ccnd1) Antikörper
  • cyclin D1 (Ccnd1) Antikörper
  • cyclin D1 (ccnd1-a) Antikörper
  • AI327039 Antikörper
  • bcl-1 Antikörper
  • BCL1 Antikörper
  • cb161 Antikörper
  • CCND1 Antikörper
  • ccnd1a Antikörper
  • ccnd1b Antikörper
  • ccndbp1 Antikörper
  • cD1 Antikörper
  • cycd1 Antikörper
  • Cyl-1 Antikörper
  • D11S287E Antikörper
  • etID37810.7 Antikörper
  • fb52e01 Antikörper
  • fc45c08 Antikörper
  • fc83a12 Antikörper
  • id:ibd1198 Antikörper
  • PRAD1 Antikörper
  • U21B31 Antikörper
  • wu:fb52e01 Antikörper
  • wu:fc45c08 Antikörper
  • wu:fc83a12 Antikörper
  • ZHM Antikörper

Bezeichner auf Proteinebene für anti-Cyclin D1 (CCND1) Antikörper

G1/S-specific cyclin-D1 b , cyclin D1 b , parathyroid adenomatosis 1 , cyclin D1 (PRAD1: parathyroid adenomatosis 1) , Cyclin-D1-binding protein 1 homolog , cyclin Dx , cyclin-D1-binding protein 1 homolog , zebrafish homolog of Maid , cyclin D1 , G1/S-specific cyclin-D1 , B-cell CLL/lymphoma 1 , B-cell lymphoma 1 protein , BCL-1 oncogene , PRAD1 oncogene , G1/S-specific cyclin-D1 a , cyclin D1 a (PRAD1: parathyroid adenomatosis 1)

GENE ID SPEZIES
379161 Xenopus laevis
448045 Xenopus (Silurana) tropicalis
495493 Xenopus laevis
548862 Xenopus (Silurana) tropicalis
553373 Danio rerio
574320 Macaca mulatta
747688 Pan troglodytes
100037407 Felis catus
100306852 Salmo salar
595 Homo sapiens
449028 Canis lupus familiaris
100009036 Oryctolagus cuniculus
12443 Mus musculus
58919 Rattus norvegicus
100729808 Cavia porcellus
100171625 Pongo abelii
379937 Xenopus laevis
396341 Gallus gallus
524530 Bos taurus
30222 Danio rerio
100144763 Ovis aries
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