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anti-AKT (AKT1) Antikörper

anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 Antikörper (AKT1)
Auf finden Sie aktuell 1251 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antikörper von 43 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen AKT Kits (47) und AKT Proteine (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1438 AKT Produkte verfügbar.
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

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Am meisten referenzierte anti-AKT Antikörper

  1. Chicken Polyclonal AKT Primary Antibody für EIA, WB - ABIN401485 : Pino, Alata, Dedonder, Jouvet, Sakota, Sekiya: Photon induced isomerization in the first excited state of the 7-azaindole-(H2O)3 cluster. in Physical chemistry chemical physics : PCCP 2011 (PubMed)
    Zeige alle 7 Referenzen für ABIN401485

  2. Human Polyclonal AKT Primary Antibody für DB, EIA - ABIN358371 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Zeige alle 5 Referenzen für ABIN358371

  3. Human Monoclonal AKT Primary Antibody für EIA, IHC (fro) - ABIN400791 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Zeige alle 4 Referenzen für ABIN400791

  4. Chimpanzee Monoclonal AKT Primary Antibody für EIA, IF - ABIN400785 : Staal: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. in Proceedings of the National Academy of Sciences of the United States of America 1987 (PubMed)
    Zeige alle 4 Referenzen für ABIN400785

  5. Human Monoclonal AKT Primary Antibody für EIA, IF - ABIN400786 : Lawlor, Alessi: PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? in Journal of cell science 2001 (PubMed)
    Zeige alle 4 Referenzen für ABIN400786

  6. Human Polyclonal AKT Primary Antibody für IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)
    Zeige alle 2 Referenzen für ABIN725195

  7. Chicken Polyclonal AKT Primary Antibody für EIA, IHC (fro) - ABIN117897 : Alessi: Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture. in Biochemical Society transactions 2001 (PubMed)
    Zeige alle 2 Referenzen für ABIN117897

  8. Human Polyclonal AKT Primary Antibody für FACS, IHC (p) - ABIN654500 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. in PLoS ONE 2010 (PubMed)

Weitere Antikörper gegen AKT Interaktionspartner

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Interaktionspartner

  1. subtle manipulation of foxo (zeige FOXO Antikörper) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  2. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  3. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  4. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  5. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (zeige GRIN1 Antikörper) localization, and postsynaptic membrane elaboration

  6. Tsc2 (zeige TSC2 Antikörper) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (zeige TSC2 Antikörper) mutants, leading to the hypothesis that Tsc2 (zeige TSC2 Antikörper) and Akt might work via the same genetic pathway to regulate synapse growth.

  7. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  8. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (zeige PTEN Antikörper) and microRNA bantam.

  9. Overexpression of Akt enhanced Sindbis virus replication.

  10. Perturbation of the Akt/Gsk3-beta (zeige GSK3b Antikörper) signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Interaktionspartner

  1. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (zeige FNTA Antikörper), which further represses the activity of K(+) channel (zeige KCNC4 Antikörper) AKT1 in Arabidopsis.

  2. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  3. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  4. These findings provide further insights into the signaling network consisting of CBL (zeige CBL Antikörper)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  5. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  6. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  7. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  8. CIPK23 directly phosphorylates the K+ transporter AKT1

  9. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (zeige CA2 Antikörper)+)-dependent manner, connecting the Ca(2 (zeige CA2 Antikörper)+) signal to K(+) uptake through activation of a K(+) channel (zeige KCNC4 Antikörper).

  10. AtAKT1 mediates K+ absorption at high concentrations, and remains active in the presence of NH4+ although activity is reduced.

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Interaktionspartner

  1. Results suggest a role of ST6GalNAc I (zeige ST6GALNAC1 Antikörper) in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT/NF-kappa B (zeige NFKB1 Antikörper) signaling, and ST6GalNAc I (zeige ST6GALNAC1 Antikörper) might be a marker for the prognosis and therapy of hepatocarcinoma.

  2. The data indicate that the balanced activities of two related serine/threonine kinases, AKT and SGK1 (zeige SGK1 Antikörper), critically govern the embryo implantation process.

  3. These results suggest that DDI may improve insulin (zeige INS Antikörper) sensitivity through the activation of Akt signaling, which leads to enhanced glucose uptake.

  4. observations revealed that the alteration of PKB-GSK-3beta axis, Plk-1, and Aurora kinase-A expressions in HSPC compartment due to DNA damage response was associated with the proliferative impairment and apoptosis during aplastic anemia.

  5. A20 (zeige TNFAIP3 Antikörper) reduces lipid storage and inflammation in hypertrophic adipocytes via p38 (zeige CRK Antikörper) and Akt signaling.

  6. the mTORC2 (zeige CRTC2 Antikörper)/Akt/NFkappaB pathway-mediated activation of TRPC6 (zeige TRPC6 Antikörper) participates in adriamycin-induced podocyte apoptosis.

  7. Ambient fine particulate matter-induced myocarditis is mediated by EGFR (zeige EGFR Antikörper)/Akt signaling and overexpression of NLRP3 (zeige NLRP3 Antikörper) and NLRP12 (zeige NLRP12 Antikörper).

  8. GSK3b (zeige GSK3b Antikörper) may up-regulate BK channels, an effect disrupted by lithium or additional expression of AKT and possibly participating in the regulation of cell volume and excitability.

  9. Akt1 regulates cell division and F-actin rearrangement in mouse fertilized eggs.

  10. The results suggest that KCa3.1 (zeige KCNN4 Antikörper) activation contributes to dysfunctional tubular autophagy in diabetic nephropathy through PI3K/Akt/mTOR (zeige FRAP1 Antikörper) signaling pathways.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Interaktionspartner

  1. Inhibition of protooncogenic microRNA-181a may suppress proliferation and invasion and promote apoptosis of cervical cancer cells through the PTEN (zeige PTEN Antikörper)/Akt/FOXO1 (zeige FOXO1 Antikörper) pathway.

  2. the potentially functional AKT1 rs2494752 SNP may affect Gastric Adenocarcinoma susceptibility, likely by modulating the AKT1 promoter transcriptional activity

  3. our results highlight that the Nox1 (zeige NOX1 Antikörper)/AKT signaling pathway plays an important role in cell survival in oral squamous cell carcinoma (OSCC) cells.

  4. Phosphorylation level of Akt declined from 138.45+/-13.8 to 69.9+/-29.7% in SGC (zeige SGCB Antikörper)-7901, and from 115.5+/-26.6 to 49.07+/-27% in MGC-803 and phosphorylation level of mTOR (zeige FRAP1 Antikörper) also significantly decreased.While apoptosis of gastric cancer(GA) cells increased which we verified with apoptosis proteins and staining analysis. Our data showed that RLIP76 (zeige RALBP1 Antikörper) plays a significant oncogenic role in GC and it maybe a potential target in GC

  5. Our study suggested that CXCR7 (zeige CXCR7 Antikörper) plays an important proangiogenic role in hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)). via activation of the AKT pathway. So CXCR7 (zeige CXCR7 Antikörper) may be a potential target for antiangiogenic therapy in HCC (zeige FAM126A Antikörper)

  6. Findings demonstrate a new role of microRNA 185 as a key regulator of hepatocellular carcinoma via autophagy by dysregulation of AKT1 pathway.

  7. the phosphorylation levels of ErbB2 (zeige ERBB2 Antikörper), ErbB3 (zeige ERBB3 Antikörper) and Akt and the protein levels of cyclin D1 (zeige CCND1 Antikörper) were decreased by lapatinib treatment of HSC3, HSC4 and Ca9 (zeige CA9 Antikörper)-22 cells

  8. enhanced NEK2 (zeige NEK2 Antikörper) expression in hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) promotes HCC (zeige FAM126A Antikörper) progression and drug resistance by promoting PP1 (zeige PPA1 Antikörper)/Akt and Wnt (zeige WNT2 Antikörper) pathway activation, which may represent a new therapeutic target for HCC (zeige FAM126A Antikörper).

  9. Our results demonstrated that NC inhibits development of glioblastoma multiforme (GBM) by targeting the PI3K (zeige PIK3CA Antikörper)/Akt/mTOR (zeige FRAP1 Antikörper) signaling pathway and provides a potential therapeutic agent for the treatment of GBM.

  10. The authors found that Akt interacts with HIV-1 Nef protein. In primary T cells treated with exogenous Nef or acutely infected with Nef-expressing HIV-1 in vitro, Akt became phosphorylated on serine(473) and threonine(308).

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Interaktionspartner

  1. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  2. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  3. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  4. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  5. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  6. findings show that megalin (zeige LRP2 Antikörper) is the sensor that determines whether cells will be protected or injured by albumin (zeige ALB Antikörper); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  7. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  8. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

  9. in VSMCs exposed to hyperglycemia, IGF-I (zeige IGF1 Antikörper) stimulation of Shc (zeige SHC1 Antikörper) facilitates the transfer of Grb2 (zeige GRB2 Antikörper) to p85 (zeige ARHGEF7 Antikörper) resulting in enhanced PI3K activation and AKT phosphorylation leading to enhanced cell proliferation and migration

  10. There was no correlation of infarct size with expression or phosphorylation of AKT in ischemic postconditioning.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Interaktionspartner

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (zeige CTNNB1 Antikörper) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (zeige CAV1 Antikörper) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (zeige TGM2 Antikörper) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (zeige GSK3b Antikörper), and NF-kappaB (zeige NFKB1 Antikörper).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (zeige NOX1 Antikörper), reactive oxygen species, and PI3-kinase (zeige PIK3CA Antikörper) in stimulated NO release.

  6. PI3K/Akt and p53 (zeige TP53 Antikörper) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (zeige FRAP1 Antikörper), p70S6K (zeige RPS6KB1 Antikörper), and ERK1/2 (zeige MAPK1/3 Antikörper).

  8. Gab1 (zeige GAB1 Antikörper) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (zeige NOS3 Antikörper) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (zeige NOS3 Antikörper) phosphorylation and suppresses tumor necrosis factor alpha (zeige TNF Antikörper)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (zeige TSC2 Antikörper) and activates mTOR (zeige FRAP1 Antikörper) and ribosomal protein S6 (zeige RPS6 Antikörper) kinase (zeige RPS6KB1 Antikörper) signaling in an AKT-independent manner

AKT (AKT1) Antigen-Profil

Beschreibung des Gens

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) Antikörper
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) Antikörper
  • CG4006 gene product from transcript CG4006-RA (Akt1) Antikörper
  • potassium channel AKT1 (KT1) Antikörper
  • thymoma viral proto-oncogene 1 (Akt1) Antikörper
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Antikörper
  • akt Antikörper
  • akt-1 Antikörper
  • Akt/PKB Antikörper
  • akt1 Antikörper
  • ATAKT1 Antikörper
  • CG4006 Antikörper
  • CWS6 Antikörper
  • D-Akt Antikörper
  • dakt Antikörper
  • dAKT/dPKB Antikörper
  • dAkt/PKB Antikörper
  • dakt1 Antikörper
  • DAKT1/PKB Antikörper
  • Dmel\\CG4006 Antikörper
  • dPKB Antikörper
  • DRAC-PK Antikörper
  • DRAC-PK66 Antikörper
  • DRAC-PK85 Antikörper
  • F18A8.2 Antikörper
  • F18A8_2 Antikörper
  • K+ transporter 1 Antikörper
  • l(3)04226 Antikörper
  • l(3)89Bq Antikörper
  • p-Akt Antikörper
  • pAkt Antikörper
  • PKB Antikörper
  • PKB-ALPHA Antikörper
  • PKB/Akt Antikörper
  • PKB/dAKT Antikörper
  • PKBalpha Antikörper
  • PRKBA Antikörper
  • Rac Antikörper
  • RAC-ALPHA Antikörper
  • RacPK Antikörper
  • v-akt Antikörper
  • v-akt1 Antikörper
  • xAct Antikörper

Bezeichner auf Proteinebene für AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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