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anti-Human KIF5B Antikörper:
anti-Mouse (Murine) KIF5B Antikörper:
anti-Rat (Rattus) KIF5B Antikörper:
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Human Polyclonal KIF5B Primary Antibody für IHC, ELISA - ABIN184774
Semiz, Park, Nicoloro, Furcinitti, Zhang, Chawla, Leszyk, Czech: Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules. in The EMBO journal 2003
Show all 3 Pubmed References
Cow (Bovine) Polyclonal KIF5B Primary Antibody für IHC, WB - ABIN2778184
Diefenbach, Diefenbach, Douglas, Cunningham: The ribosome receptor, p180, interacts with kinesin heavy chain, KIF5B. in Biochemical and biophysical research communications 2004
Show all 2 Pubmed References
BORC and Arl8 (zeige ARL5B Antikörper) function upstream of two structurally distinct kinesin types: kinesin-1 (KIF5B) and kinesin-3 (KIF1Bbeta and KIF1A (zeige KIF1A Antikörper)).
KIF5B gene rearrangement plays a role in the pathogenesis of papillary thyroid cancer.
compared to those of brain, on MCF7 microtubules, kinesin-1's processivity is significantly reduced although its velocity is only slightly altered
these observations identify a previously unappreciated role for KIF5B in mediating the Nup358 (zeige RANBP2 Antikörper) dependent nuclear import of the HIV-1 viral genome during infection.
For Fat3 (zeige FAT3 Antikörper), the Kif5 (zeige KIF5A Antikörper)-ID is regulated by alternative splicing, and the timecourse of splicing suggests that the distribution of Fat3 (zeige FAT3 Antikörper) may switch between early and later stages of retinal development. In contrast, P75NTR (zeige NGFR Antikörper) binding to Kif5B is enhanced by tyrosine phosphorylation and thus has the potential to be dynamically regulated on a more rapid time scale
Data suggest that light-chain subunits/fragments of kinesin-1 inhibit the pathological aggregation of amyloid(beta).
In this work, we performed normal mode analysis with elastic network model using different conformation of kinesin to determine the effect of tail binding.
KIF5B is essential for Ostm1 (zeige OSTM1 Antikörper) intracellular dispersion.
differences between the structural kinetics of Eg5 (zeige KIF11 Antikörper) and kinesin-1 yield insights into how these two motors adapt their enzymologies for their distinct functions
data suggest one-step screening platform for KIF5B-RET (zeige RET Antikörper) as well as EGFR (zeige EGFR Antikörper), K-RAS (zeige HRAS Antikörper), ALK (zeige ALK Antikörper) oncogenic mutations be necessary for lung adenocarcinoma patients
High KIF5B expression is associated with Lung Metastasis of Breast Cancer.
It was concluded that selective deletion of Kif5b in adipose tissue exacerbates HFD-induced obesity and its associated metabolic disorders, partly through a decrease in energy expenditure, dysregulation of adipokine secretion, and insulin (zeige INS Antikörper) signaling.
PI3K-dependent formation of a kinesin-1/Slp3/Rab27b (zeige RAB27B Antikörper) complex is critical for the microtubule-dependent movement of secretory granules required for mast cell degranulation.
The KIF5B level was up-regulated during 3T3-L1 adipogenesis. This increase in cytosolic KIF5B was synchronized with the induction of adiponectin. Endogenous KIF5B and adiponectin were partially colocalized at the peri (zeige POSTN Antikörper)-nuclear and cytosolic regions.
results indicate that NCAM (zeige NCAM1 Antikörper) is delivered to the cell surface through a kinesin-1-mediated transport mechanism in a PAK1 (zeige PAK1 Antikörper)-dependent manner.
Kif5b expression during mouse kidney development
we showed that the KIF5B-RET (zeige RET Antikörper) fusion gene is oncogenic in lung alveolar epithelial cells in vivo.
nesprin-dependent recruitment of kinesin-1 to the nuclear envelope through the interaction of a conserved LEWD motif with kinesin light chain might be a general mechanism for cell-type-specific nuclear positioning during development.
KIF5B is critical in suppressing chromosomal instability at the early stages of female meiotic cell development and mitotic cell division.
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).
kinesin heavy chain
, kinesin-like protein KHC
, Kinesin heavy chain
, kinesin heavy chain isoform 5A
, kinesin family member 5B
, kinesin family member 5A
, kinesin-1 heavy chain
, conventional kinesin heavy chain
, kinesin 1 (110-120kD)
, ubiquitous kinesin heavy chain
, kinesin heavy chain member 5B, ubiquitous