C-MYC Proteine (MYC)

Bezeichnung:
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteine (MYC)
Auf www.antikoerper-online.de finden Sie aktuell 29 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen C-MYC Antikörper (713) und C-MYC Kits (55) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 821 C-MYC Produkte verfügbar.
Synonyme:
AU016757, bHLHe39, C-MYC, CMyc, LOC100136746, mMyc, MRTL, MYC, Myc2, MYCC, Niard, Nird, RNCMYC, zc-myc
alle Proteine anzeigen Gen GeneID UniProt
MYC 24577 P09416
MYC 17869 P01108
MYC 4609 P01106

Weitere Synonyme anzeigen

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Am meisten referenzierte C-MYC Proteine

  1. Human C-MYC Protein expressed in HEK-293 Cells - ABIN2715370 : Garcia-Sanz, Quintanilla, Lafita, Moreno-Bueno, García-Gutierrez, Tabor, Varela, Shiio, Larsson, Portillo, Leon: Sin3b interacts with Myc and decreases Myc levels. in The Journal of biological chemistry 2014 (PubMed)
    Zeige alle 3 Referenzen für 2715370

  2. Human C-MYC Protein expressed in Escherichia coli (E. coli) - ABIN1047412 : Battey, Moulding, Taub, Murphy, Stewart, Potter, Lenoir, Leder: The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma. in Cell 1983 (PubMed)
    Zeige alle 3 Referenzen für 1047412

Weitere Proteine zu C-MYC Interaktionspartnern

Mouse (Murine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Interaktionspartner

  1. by controlling both nanodomain decompaction and PolII promoter escape Myc stands as a master regulator of transcriptome amplification during B cell activation (zeige BLNK Proteine).

  2. these results indicate that PIAS1 (zeige PIAS1 Proteine) is a positive regulator of MYC.

  3. this study shows that that deletion of Sox2 (zeige SOX2 Proteine) increases the frequency of IgH:c-Myc translocations

  4. findings highlight a MYC/ERRalpha (zeige ESRRA Proteine) pathway that contributes to physiological and pathological bone loss by integrating the MYC/ERRalpha (zeige ESRRA Proteine) axis to drive metabolic reprogramming during osteoclast differentiation

  5. KrasG12D-driven proliferation of pancreatic ductal epithelial cells (PDECs) depends on an EGFR (zeige EGFR Proteine) signaling loop engaging the oncogenic transcription factor c-MYC.

  6. Data show that Emu-Myc mice lacking both p21 and PUMA (zeige BBC3 Proteine) developed lymphoma at a rate considerably longer latency than Emu-Myc;p53 (zeige TP53 Proteine)(+/-)mice.

  7. CRY2 (zeige CRY2 Proteine) and FBXL3 (zeige FBXL3 Proteine) cooperatively degrade c-MYC preventing the development of cancer.

  8. Data, including data from studies in cells from knockout mice, suggest that Prmt1 (zeige PRMT1 Proteine) activity was necessary for c-Myc binding to acetyltransferase p300 (zeige NOTCH1 Proteine) in myeloid cells; Prmt1 (zeige PRMT1 Proteine) inhibition decreases p300 (zeige NOTCH1 Proteine) recruitment to c-Myc target promoters and increased Hdac1 (zeige HDAC1 Proteine) recruitment. [Prmt1 (zeige PRMT1 Proteine), protein arginine N-methyltransferase 1 (zeige PRMT1 Proteine); c-Myc = Proto-Oncogene (zeige RAB1A Proteine) Proteins c-myc; Hdac1 (zeige HDAC1 Proteine) = histone deacetylase 1 (zeige HDAC1 Proteine)]

  9. MYC-dependent attenuation of GCLC (zeige GCLC Proteine) by miR (zeige MLXIP Proteine)-18a contributes to GSH depletion in vivo, and low GSH corresponds with increased sensitivity to oxidative stress in tumors.

  10. MYC mediates cell cycle re-entry of Trp53 (zeige TP53 Proteine)-altered hepatocytes via AURKA (zeige AURKA Proteine) binding.

Zebrafish V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Interaktionspartner

  1. Apoptosis was also observed with myca expression; introduction of homozygous tp53 (zeige TP53 Proteine)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  2. MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.

Human V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Interaktionspartner

  1. Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs

  2. elevated MYC levels confer resistance to pharmacologic inhibitors of BCR (zeige BCR Proteine) signaling, which has significant implications for B-cell non-Hodgkin lymphoma treatment.

  3. study revealed a tumorigenic effect of long nnon-coding RNA PCAT-1 in Colorectal Ccancer cells, and this effect is partly dependent on the inhibition of c-myc.

  4. results identify the novel immunomodulatory role of MYC in human plasmacytoid dendritic cells and may add to our understanding of aberrant plasmacytoid dendritic cells function in cancer and autoimmune disease

  5. High MYC expression is associated with lung cancer.

  6. The results strongly suggest that the combination of MYCL plus MYOD1 (zeige MYOD1 Proteine) may promote direct conversion of human fibroblasts into functional myoblasts that could potentially be used for regenerative therapy for muscle diseases and congenital muscle defects.

  7. EGFR (zeige EGFR Proteine) amplification/EGFRvIII mutation can repress the expression of Pri-miR (zeige MLXIP Proteine)-524 by histone modification. MiR (zeige MLXIP Proteine)-524-3p and miR (zeige MLXIP Proteine)-524-5p inhibited TGF/beta (zeige TGFB1 Proteine), Notch (zeige NOTCH1 Proteine) and the Hippo pathway by targeting Smad2 (zeige SMAD2 Proteine), Hes1 and Tead1 (zeige TEAD1 Proteine), respectively; these pathways repressed their common downstream transcription factor, C-myc.

  8. The data provided new insights into the functional interaction between the KRAS and MYC pathways across various cancer types

  9. these results indicate that PIAS1 (zeige PIAS1 Proteine) is a positive regulator of MYC.

  10. MYC and BCL2 (zeige BCL2 Proteine) genetic alterations were profiled using next-generation sequencing and high-resolution single nucleotide polymorphism array in 347 de novo diffuse large B-cell lymphoma cases.

Rabbit V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Interaktionspartner

  1. report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development

Cow (Bovine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Interaktionspartner

  1. Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.

C-MYC (MYC) Protein Überblick

Protein Überblick

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Alternative names and synonyms associated with C-MYC (MYC)

  • v-myc myelocytomatosis viral oncogene homolog (LOC100136746)
  • myelocytomatosis oncogene (Myc)
  • myelocytomatosis oncogene a (myca)
  • v-myc avian myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
  • AU016757 Protein
  • bHLHe39 Protein
  • C-MYC Protein
  • CMyc Protein
  • LOC100136746 Protein
  • mMyc Protein
  • MRTL Protein
  • MYC Protein
  • Myc2 Protein
  • MYCC Protein
  • Niard Protein
  • Nird Protein
  • RNCMYC Protein
  • zc-myc Protein

Bezeichner auf Proteinebene für MYC

v-myc myelocytomatosis viral oncogene homolog , Avian myelocytomatosis viral (v-myc) oncogene homolog , myc proto-oncogene protein , myelocytomatosis viral oncogene homolog , proto-oncogene c-Myc , transcription factor p64 , v-myc avian myelocytomatosis viral oncogene homolog , c-myc proto-oncogene , C-Myc1 , c-Myc-A , cellular myelocytomatosis oncogene , cmyca , transcriptional regulator Myc-A , avian myelocytomatosis viral oncogene homolog , class E basic helix-loop-helix protein 39 , myc-related translation/localization regulatory factor , avian myelocytomatosis viral (v-myc) oncogene homolog , c-Myc , Proto-oncogene c-Myc , Transcription factor p64 , Myc proto-oncogene protein

GENE ID SPEZIES
100136746 Oncorhynchus mykiss
24577 Rattus norvegicus
17869 Mus musculus
30686 Danio rerio
4609 Homo sapiens
420332 Gallus gallus
100327265 Oryctolagus cuniculus
403924 Canis lupus familiaris
448810 Sus scrofa
511077 Bos taurus
100379628 Felis catus
443447 Ovis aries
694626 Macaca mulatta
464393 Pan troglodytes
100407754 Callithrix jacchus
100972175 Pan paniscus
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