anti-TRAF3 (TRAF3) Antikörper

anti-TNF Receptor-Associated Factor 3 Antikörper (TRAF3)
Auf finden Sie aktuell 139 TNF Receptor-Associated Factor 3 (TRAF3) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF3 Proteine (5) und TRAF3 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 163 TRAF3 Produkte verfügbar.
AI528849, amn, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, T-BAM
Alle Antikörper anzeigen Gen GeneID UniProt
TRAF3 7187 Q13114
TRAF3 22031 Q60803
TRAF3 362788  

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anti-Human TRAF3 Antikörper:

anti-Mouse (Murine) TRAF3 Antikörper:

anti-Rat (Rattus) TRAF3 Antikörper:

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Weitere Antikörper gegen TRAF3 Interaktionspartner

Human TNF Receptor-Associated Factor 3 (TRAF3) Interaktionspartner

  1. Mechanistic studies showed that HACE1 (zeige HACE1 Antikörper) exerts its inhibitory role on virus-induced signaling by disrupting the MAVS (zeige MAVS Antikörper)-TRAF3 complex.

  2. An important B cell-sp (zeige TNFRSF1A Antikörper)ecific role for TNFR-associated factor 3 is the (zeige TNFRSF1A Antikörper) inhibition of homeostatic s (zeige TLR4 Antikörper)urvival, directly relevant to the common occurrence of TNFR- (zeige TNFRSF1A Antikörper)associated factor 3 mutations in human B cell malignancies. Review.

  3. The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (tumor necrosis factor (zeige TNF Antikörper) receptor-associated factor 3) and CYLD (zeige CYLD Antikörper) (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 and CYLD (zeige CYLD Antikörper) correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.

  4. NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors

  5. Data suggest that UBR5 (zeige UBR5 Antikörper) down-regulates levels of TRAF3, a key component of Toll (zeige TLR4 Antikörper)-like receptor signaling, via the miRNA pathway; p90RSK (zeige RPS6KA1 Antikörper) is an upstream regulator of UBR5 (zeige UBR5 Antikörper); p90RSK (zeige RPS6KA1 Antikörper) phosphorylates UBR5 (zeige UBR5 Antikörper) as required for translational repression of TRAF3 mRNA. (UBR5 (zeige UBR5 Antikörper) = ubiquitin protein ligase E3 component n-recognin 5 (zeige UBR5 Antikörper) protein; TRAF3 = TNF receptor-associated factor 3; p90RSK (zeige RPS6KA1 Antikörper) = 90 kDa ribosomal protein S6 (zeige RPS6 Antikörper) kinase (zeige RPS6KB1 Antikörper))

  6. The GA genotype and GA+AA genotype of TRAF3 rs12147254 were found to increase the risk of coronary heart disease among T2DM patients. the GACGAC haplotype in TRAF3 had a protective effect on T2DM micro-macrovascular complications.

  7. These data suggest an interplay between CELF2 (zeige CELF2 PLURAL_@28810@) and hnRNP C (zeige HNRNPC PLURAL_@28810@) as the mechanistic basis for activation-dependent alternative splicing of TRAF3 exon 8.

  8. DDX3 (zeige DDX3X Antikörper) directly regulates TRAF3 ubiquitination and acts as a scaffold to co-ordinate assembly of signaling complexes downstream from MAVS (zeige MAVS Antikörper).

  9. The NleB effector limited host IFN-beta (zeige IFNB1 Antikörper) production by inhibiting Lys (zeige LYZ Antikörper)(63)-linked ubiquitination of TNF receptor-associated factor 3 (TRAF3). Inhibition was dependent on the glycosyltransferase (zeige GTDC2 Antikörper) activity of NleB.

  10. TRAF3 epigenetics may significantly contribute to the variability of clopidogrel response and recurrence of ischemic events in patients with stroke.

Mouse (Murine) TNF Receptor-Associated Factor 3 (TRAF3) Interaktionspartner

  1. In B lymphocytes, TNFR (zeige TNFRSF1A Antikörper)-associated factor 3 inhibits signaling by TNFR (zeige TNFRSF1A Antikörper) superfamily receptors, Toll (zeige TLR4 Antikörper)-like receptors, and interleukin-6R. In T lymphocytes, TNFR (zeige TNFRSF1A Antikörper)-associated factor 3 is required for normal signaling by the T cell antigen receptor, while inhibiting signaling by the interleukin-2 (zeige IL2 Antikörper) receptor. Cytoplasmic TNFR (zeige TNFRSF1A Antikörper) -associated factor 3 restrains nuclear factor-kappaB2 activation in both T and B cells. Review.

  2. TRAF3 may likely induce apoptosis and resistance to proliferation and may be a new target to inhibit the cyst formation in polycystic kidney disease by regulating the NF-kappaB (zeige NFKB1 Antikörper) signaling pathway Bcl-2 (zeige BCL2 Antikörper) and Bcl-xl (zeige BCL2L1 Antikörper) activity.

  3. this study shows that TRAF3 ubiquitination triggers expulsion of intracellular bacteria by exocyst complex

  4. NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors

  5. Data (including data from studies using knockout mice) suggest that RANKL (zeige TNFSF11 Antikörper) enhances TNF (zeige TNF Antikörper)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 (zeige TRAF6 Antikörper) by degrading Traf3, a known inhibitor of osteoclastogenesis. (RANKL (zeige TNFSF11 Antikörper) = osteoclast differentiation factor (zeige TNFSF11 Antikörper); TNF (zeige TNF Antikörper) = tumor necrosis factor (zeige TNF Antikörper); Traf (zeige TRAF1 Antikörper) = TNF (zeige TNF Antikörper) receptor-associated factor)

  6. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 (zeige FOSL1 Antikörper) "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3), TIR domain-containing adapter inducing IFN-beta (zeige IFNB1 Antikörper) (TRIF (zeige RNF138 Antikörper)), and Tank-binding kinase 1 (TBK1 (zeige TBK1 Antikörper)) via impairing K63-linked polyubiquitination of TRAF3 and TRIF (zeige RNF138 Antikörper).

  7. These findings reveal a novel mechanism that endotoxin tolerance reprograms mitogen-activated protein kinase (zeige MAPK1 Antikörper) signaling by suppressing Pellino 1 (zeige PELI1 Antikörper)-mediated K63-linked ubiquitination of cIAP2 (zeige BIRC3 Antikörper), K48-linked ubiquitination, and degradation of TRAF3.

  8. Findings establish CK1varepsilon as a regulator of antiviral innate immune responses and indicate a novel mechanism of immunoregulation that involves CK1varepsilon-mediated phosphorylation of TRAF3.

  9. Hepatocyte TRAF3 promotes liver steatosis and insulin (zeige INS Antikörper) resistance through targeting TAK1 (zeige NR2C2 Antikörper)-dependent signaling.

  10. findings identify TRAF3 and PTPN22 (zeige PTPN22 Antikörper) as inhibitors of IL-6R signaling in B cells and reveal a previously uncharacterized role for TRAF3 in the regulation of plasma cell differentiation

TRAF3 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Alternative names and synonyms associated with TRAF3

  • TNF receptor-associated factor 3 (TRAF3) Antikörper
  • TNF receptor-associated factor 3 (Traf3) Antikörper
  • Tnf receptor-associated factor 3 (Traf3) Antikörper
  • AI528849 Antikörper
  • amn Antikörper
  • CAP-1 Antikörper
  • CAP1 Antikörper
  • CD40bp Antikörper
  • CRAF1 Antikörper
  • IIAE5 Antikörper
  • LAP1 Antikörper
  • T-BAM Antikörper

Bezeichner auf Proteinebene für TRAF3

CD40 associated protein 1 , CD40 binding protein , CD40 receptor associated factor 1 , LMP1-associated protein 1 , CD40 receptor-associated factor 1 , TRAFAMN , TNF receptor-associated factor 3

7187 Homo sapiens
22031 Mus musculus
362788 Rattus norvegicus
Ausgewählte Anbieter für anti-TRAF3 (TRAF3) Antikörper
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