TNFRSF1B Proteine (TNFRSF1B)

Bezeichnung:
Tumor Necrosis Factor Receptor Superfamily, Member 1B Proteine (TNFRSF1B)
Auf www.antikoerper-online.de finden Sie aktuell 43 Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Proteine von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFRSF1B Antikörper (292) und TNFRSF1B Kits (51) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 408 TNFRSF1B Produkte verfügbar.
Synonyme:
CD120b, LOC100218184, MGC83471, p75, p75TNFR, TANK, TBPII, TNF-alphaR2, TNF-R-II, TNF-R2, TNF-R75, TNF-RII/TNFRSF1B, TNFalpha-R2, TNFBR, Tnfr-1, TNFR-II, TNFR1B, Tnfr2, TNFR80, TNFRII, TNFRSF1B, TRAF2
alle Proteine anzeigen Gen GeneID UniProt
TNFRSF1B 7133 P20333
TNFRSF1B 21938 P25119
TNFRSF1B 156767 Q80WY6

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Am meisten referenzierte TNFRSF1B Proteine

  1. Mouse (Murine) TNFRSF1B Protein expressed in Human Cells - ABIN2007373 : Wassink, Crowe, Andreasen: Tumor necrosis factor receptor-II: heritability and effect on brain morphology in schizophrenia. in Molecular psychiatry 2000 (PubMed)
    Zeige alle 3 Referenzen für 2007373

  2. Human TNFRSF1B Protein expressed in Human Cells - ABIN2002807 : Chung, Guan, Yuan, Albina, Chin: Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II. in Molecular and cellular biology 2005 (PubMed)
    Zeige alle 3 Referenzen für 2002807

  3. Human TNFRSF1B Protein expressed in HEK-293 Cells - ABIN2181842 : Ziegenhagen, Fitschen, Martinet, Schlaak, Müller-Quernheim: Serum level of soluble tumour necrosis factor receptor II (75 kDa) indicates inflammatory activity of sarcoidosis. in Journal of internal medicine 2000 (PubMed)
    Zeige alle 3 Referenzen für 2181842

  4. Cynomolgus TNFRSF1B Protein expressed in Human Cells - ABIN2009844 : Nozar, Philippe, Fabrice, Silvia, Marc: Acute pure spontaneous subdural haematoma from ruptured intracranial aneurysms. in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2010 (PubMed)
    Zeige alle 2 Referenzen für 2009844

Weitere Proteine zu TNFRSF1B Interaktionspartnern

Cow (Bovine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Interaktionspartner

  1. These results show an unclear effect of considered T>C polymorphism on TNF-RII gene expression in bovine leukocytes and they suggest the involvement of BLV in modifying the TNF-RII expression in BLV-infected cows.

  2. These results suggest that the endometrium might lower the TNF (zeige TNF Proteine) concentration in the blastocyst by (1) regulating TNF (zeige TNF Proteine) secretion into the uterine fluid and (2) inducing decreased TNF (zeige TNF Proteine) and TNFR2 mRNA transcription in the embryo.

  3. These results suggest that TNF-alpha (zeige TNF Proteine) sources include immune cells, as well as large and small luteal cells, and that TNF-RI (zeige TNFRSF1A Proteine) and TNF-RII are present in the luteal cells of the bovine corpus luteum.

  4. The expression and cellular localization of tumor necrosis factor-alpha (TNF (zeige TNF Proteine)) and its receptors (TNFRI (zeige TNFRSF1A Proteine) and TNFRII) mRNAs and proteins, were determined.[TNFRII]

Human Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Interaktionspartner

  1. Serum TNFR2 levels were elevated in lupus nephritis patients versus controls.

  2. Adalimumab bound to monocyte membrane TNF (zeige TNF Proteine) from rheumatoid arthritis patients and unexpectedly enhanced its expression and its binding to TNF-RII expressed on T reg (zeige EXTL3 Proteine) cells.

  3. Voxel-based morphometry was used to analyse the associations between TNFRSF1B (rs1061624) genotypes and grey matter structure. Analysis of the TNFRSF1B SNP rs1061624 yielded a significant association with hippocampal but not with striatal volume, whereby G homozygotes were associated with increased volumes relative to A homozygotes and heterozygotes.

  4. Circulating TNFR1 (zeige TNFRSF1A Proteine) and 2 were shown to be associated with cardiovascular disease, independent of age, sex, inflammatory markers, and other cardiovascular disease risk factors, in the chronic kidney disease patients

  5. Data suggest that TRAF2 (TNF receptor-associated factor 2 (zeige TRAF2 Proteine)) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1 (zeige TNFRSF1A Proteine))-induced apoptosis, (2) TNFR2- (tumor necrosis factor (zeige TNF Proteine) receptor type 2)-induced non-canonical NFkappaB (zeige NFKB1 Proteine) signaling, and (3) TNF- (tumor necrosis factor (zeige TNF Proteine))-induced necroptosis. [REVIEW]

  6. Our results demonstrated that Treg frequencies and TNFR2 expression on Tregs are increased in sarcoidosis, followed by a decline during infliximab therapy, suggesting a pathophysiological role of this T cell subset.

  7. Data indicate that plasma concentrations of TNFR1 (zeige TNFRSF1A Proteine) and TNFR2 are elevated in pediatric lupus nephritis.

  8. TNFR1 is the major pro-inflammatory mediator of TNF-alpha in fibroblast-like synoviocytes (FLS), whereas TNFR2, may act as an immunosuppressor in FLS for the prevention of overwhelming inflammatory reactions.

  9. identified 6 known and 4 novel variations in 6 different exons of TNFR2 gene; out of these identified variations, 5 known variations were found to be significantly associated with the risk of cervical cancer; postmenopausal women having CAAGC + CTGCC haplotypes in TNFR2 gene along with HPV infection and tobacco consumption may lead to the development of cervical cancer

  10. LTbetaR is essential for efficient liver regeneration and cooperates with TNFRp55 (zeige TNFRSF1A Proteine) in this process. Differences in survival kinetics strongly suggest distinct functions for these two cytokine receptors in liver regeneration.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Interaktionspartner

  1. study reports an important role for TNFR2 on low-affinity-primed secondary effector CD8 (zeige CD8A Proteine)+ T cells; results demonstrate the importance of TNF (zeige TNF Proteine) signaling in low-affinity, cross-reactive CD8 (zeige CD8A Proteine)+ T cell responses during heterologous immunity

  2. TNF (zeige TNF Proteine) plays an inhibitory role in modulating myocardial SDF-1 (zeige CXCL12 Proteine) production and blockade of TNF (zeige TNF Proteine) signaling by ablation of TNFR1 (zeige TNFRSF1A Proteine) and TNFR2 genes increased SDF-1 (zeige CXCL12 Proteine) expression in the heart. These data expand on TNF (zeige TNF Proteine) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 (zeige CXCL12 Proteine) and TNFR (zeige TNFRSF1A Proteine)-derived actions in hopes of advancing ischemic heart injury treatments.

  3. Results suggest that elevated TNF (zeige TNF Proteine) in the heart, via TNFR1 (zeige TNFRSF1A Proteine) and TNFR2, restrains cardiomyocyte differentiation of resident cardiac stem cells and may enhance adrenergic activation, both effects that would reduce the effectiveness of endogenous cardiac repair and the response to exogenous stem cell therapy, while promoting adverse cardiac remodeling.

  4. Report chronic inflammatory multiorgan hepatobiliary pancreatitis, along with fibrosis and calculi formation induced by oral dibutyltin administration in TNFR1 (zeige TNFRSF1A Proteine)/R2 deficient mice.

  5. These findings implicate TNF (zeige TNF Proteine)-receptor signaling cascades in the regulation of homeostatic plasticity of denervated networks and suggest an important role for TNFalpha (zeige TNF Proteine)-signaling in the course of neurological diseases accompanied by deafferentation.

  6. TNF (zeige TNF Proteine) receptor 1 (TnfR1 (zeige TNFRSF1A Proteine)) signaling is believed to be a major mediator of the cytotoxicity of Tnf-a (zeige TNF Proteine) through activation of caspases.

  7. our findings implicate TNFR2 in supporting myeloid-derived suppressor cells -mediated immune suppression and metastasis in the liver

  8. TNFR2 blockade appears to disrupt commensal bacteria-host immune symbiosis to reveal autoimmune demyelination in genetically susceptible mice.

  9. TNFR2 protects mice from colitis by inhibiting the expansion of colonic CD8 (zeige CD8A Proteine)(+) T cells.

  10. Collectively, these results demonstrate that TNFR2-bearing CD8 (zeige CD8A Proteine)(+) T cells and TNFR1 (zeige TNFRSF1A Proteine)-bearing non-CD8 (zeige CD8A Proteine)(+) T cells contribute significantly to oviduct pathology following genital chlamydial infection.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Interaktionspartner

  1. Retinal ischemia results in increased expression of TNF-alpha (zeige TNF Proteine) and its receptors (TNF-R1 (zeige TNFRSF1A Proteine) and TNF-R2).

  2. Porcine TNFR2 (1,125 bp, 375 amino acid residues), which contains specific amino acid region of transmembrane, indicated high identities with human and murine TNFR2

TNFRSF1B Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Alternative names and synonyms associated with TNFRSF1B

  • TNF receptor-associated factor 2 (TRAF2)
  • TNF receptor-associated factor 2 (traf2)
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6)
  • TNF receptor-associated factor 3 (LOC100218184)
  • TNF receptor-associated factor 3 (LOC100359083)
  • TRAF family member-associated NFKB activator (TANK)
  • tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B)
  • tumor necrosis factor receptor superfamily, member 1B (LOC100222629)
  • tumor necrosis factor receptor superfamily, member 1b (Tnfrsf1b)
  • tumor necrosis factor receptor superfamily, member 1B (Tnfrsf1b)
  • CD120b Protein
  • LOC100218184 Protein
  • MGC83471 Protein
  • p75 Protein
  • p75TNFR Protein
  • TANK Protein
  • TBPII Protein
  • TNF-alphaR2 Protein
  • TNF-R-II Protein
  • TNF-R2 Protein
  • TNF-R75 Protein
  • TNF-RII/TNFRSF1B Protein
  • TNFalpha-R2 Protein
  • TNFBR Protein
  • Tnfr-1 Protein
  • TNFR-II Protein
  • TNFR1B Protein
  • Tnfr2 Protein
  • TNFR80 Protein
  • TNFRII Protein
  • TNFRSF1B Protein
  • TRAF2 Protein

Bezeichner auf Proteinebene für TNFRSF1B

TNF receptor-associated factor 2 , E3 ubiquitin-protein ligase TRAF6 , TNF receptor-associated factor 6 , TNF receptor-associated factor 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2-like , tumor necrosis factor receptor superfamily member 1B , tumor necrosis factor receptor 2 , tumor necrosis factor receptor superfamily, member 1B , TNF-R2 , TNF-RII , p75 TNF receptor , p80 TNF-alpha receptor , soluble TNFR1B variant 1 , tumor necrosis factor beta receptor , tumor necrosis factor binding protein 2 , tumor necrosis factor receptor type II , TNF receptor beta chain , TNFR-II , p75 TNFR , p75 , tumor necrosis factor receptor-II

GENE ID SPEZIES
417287 Gallus gallus
431974 Xenopus laevis
716907 Macaca mulatta
100218184 Taeniopygia guttata
100359083 Oryctolagus cuniculus
100404226 Callithrix jacchus
100458089 Pongo abelii
100474087 Ailuropoda melanoleuca
100590721 Nomascus leucogenys
338033 Bos taurus
457968 Pan troglodytes
487437 Canis lupus familiaris
715454 Macaca mulatta
100222629 Taeniopygia guttata
100240715 Ovis aries
7133 Homo sapiens
21938 Mus musculus
156767 Rattus norvegicus
100037306 Sus scrofa
395083 Gallus gallus
100723273 Cavia porcellus
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