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anti-Integrin beta 2 (ITGB2) Antikörper

Bezeichnung:
anti-Integrin beta 2 Antikörper (ITGB2)
Auf www.antikoerper-online.de finden Sie aktuell 668 Integrin beta 2 (ITGB2) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Integrin beta 2 Proteine (16) und Integrin beta 2 Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 703 Integrin beta 2 Produkte verfügbar.
Synonyme:
2E6, AI256028, AI528527, CD18, D12S370, ITGB2, LAD, LCAMB, LFA-1, Lfa1, LT-BETA-R, Ltar, LTbetaR, MAC-1, MF17, MFI7, TNF-R-III, Tnfbr, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRrp, TNFRSF3
Alle Antikörper anzeigen Gen GeneID UniProt
ITGB2 16414 P11835
ITGB2 309684  
ITGB2 3689 P05107

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Am meisten referenzierte anti-Integrin beta 2 Antikörper

  1. Human Monoclonal Integrin beta 2 Primary Antibody für Func, FACS - ABIN111902 : Drbal, Angelisová, Cerný, Hilgert, Horejsí: A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins. in Immunobiology 2001 (PubMed)
    Zeige alle 9 Referenzen für ABIN111902

  2. Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody für FACS, IHC (fro) - ABIN118151 : Trowbridge, Omary: Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. in The Journal of experimental medicine 1982 (PubMed)
    Zeige alle 5 Referenzen für ABIN118151

  3. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody für FACS - ABIN118552 : Chabanne, Marchal, Kaplanski, Fournel, Magnol, Monier, Rigal: Screening of 78 monoclonal antibodies directed against human leukocyte antigens for cross-reactivity with surface markers on canine lymphocytes. in Tissue antigens 1994 (PubMed)
    Zeige alle 3 Referenzen für ABIN118552

  4. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody für FACS - ABIN118555 : Bindon, Hale, Waldmann: Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies. in European journal of immunology 1988 (PubMed)
    Zeige alle 3 Referenzen für ABIN118555

  5. Rat (Rattus) Monoclonal Integrin beta 2 Primary Antibody für FACS, IHC (fro) - ABIN120418 : Tamatani, Kotani, Miyasaka: Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. in European journal of immunology 1991 (PubMed)
    Zeige alle 2 Referenzen für ABIN120418

  6. Human Polyclonal Integrin beta 2 Primary Antibody für IF, ELISA - ABIN1532556 : Kishimoto, OConnor, Lee, Roberts, Springer: Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. in Cell 1987 (PubMed)
    Zeige alle 2 Referenzen für ABIN1532556

  7. Human Polyclonal Integrin beta 2 Primary Antibody für IF, ELISA - ABIN1531540 : Hattori, Fujiyama, Taylor, Watanabe, Yada, Park, Toyoda, Ishii, Totoki, Choi, Groner, Soeda, Ohki, Takagi, Sakaki, Taudien, Blechschmidt, Polley, Menzel, Delabar, Kumpf, Lehmann, Patterson, Reichwald et al.: The DNA sequence of human chromosome 21. ... in Nature 2000 (PubMed)
    Zeige alle 2 Referenzen für ABIN1531540

  8. Human Monoclonal Integrin beta 2 Primary Antibody für FACS - ABIN111901 : Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells. in Blood 2001 (PubMed)

Weitere Antikörper gegen Integrin beta 2 Interaktionspartner

Mouse (Murine) Integrin beta 2 (ITGB2) Interaktionspartner

  1. NDR1 (zeige STK38 Antikörper) kinase, activated by the Rap1 (zeige TERF2IP Antikörper) signaling cascade through RAPL (zeige RASSF5 Antikörper) and Mst1 (zeige MST1 Antikörper)/Mst2 (zeige STK3 Antikörper), associated with and recruited kindlin-3 (zeige FERMT3 Antikörper) to the immunological synapses, which was required for high-affinity LFA-1 (zeige ITGAL Antikörper)/ICAM-1 (zeige ICAM1 Antikörper) binding.

  2. LTbetaR is essential for efficient liver regeneration and cooperates with TNFRp55 (zeige TNFRSF1A Antikörper) in this process. Differences in survival kinetics strongly suggest distinct functions for these two cytokine receptors in liver regeneration.

  3. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.

  4. Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 (zeige ITGAL Antikörper) activation and neutrophil arrest in vivo

  5. report that beta2 and alpha4 integrins use different RIAM (zeige APBB1IP Antikörper)-dependent and -independent pathways to undergo activation by talin

  6. Timely blockade of ICAM-1 (zeige ICAM1 Antikörper).LFA-1 (zeige ITGAL Antikörper) interaction prevents disease onset in a mouse model of emphysema.

  7. This study identified Mrp8 (zeige S100A8 Antikörper)/14 and TLR4 (zeige TLR4 Antikörper) as important modulators of the leukocyte recruitment cascade during inflammation via integrin beta2.

  8. Anti-OX40L (zeige TNFSF4 Antikörper) mAb could prolong secondary heart allograft survival based on CD40 (zeige CD40 Antikörper)/CD40L (zeige CD40LG Antikörper) and LFA-1 (zeige ITGAL Antikörper)/ICAM-1 (zeige ICAM1 Antikörper) blockade.

  9. Alzheimer's disease model mice lacking LFA-1 (zeige ITGAL Antikörper) were protected from cognitive decline

  10. Loss of the interaction between beta2-integrins and kindlin-3 (zeige FERMT3 Antikörper) abolishes the actin-linkage of integrins and the GM-CSF (zeige CSF2 Antikörper) receptor in dendritic cells.

Human Integrin beta 2 (ITGB2) Interaktionspartner

  1. K152 and D120 within the PH domain of SKAP55 (zeige SKAP1 Antikörper) regulate plasma membrane targeting and T cell receptor-mediated activation of LFA-1 (zeige ITGAL Antikörper).

  2. LIGHT and LTBR (zeige LTBR Antikörper) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.

  3. Genetic inactivation and blockade studies revealed that homophilic interactions between intercellular adhesion molecule 1 (ICAM-1 (zeige ICAM1 Antikörper)) expressed on tumor cells and MSCs, respectively, regulate the competition between tumor cells and HSPCs for binding to MSCs. Moreover, tumor cell-secreted soluble ICAM-1 (zeige ICAM1 Antikörper)(sICAM-1) also impaired HSPC (zeige PSMA7 Antikörper) adhesion via blocking CD18-ICAM-1 (zeige ICAM1 Antikörper) binding between HSPCs and MSCs

  4. The ability of simvastatin to target CR3 (zeige ITGAM Antikörper) in its ligand binding-activated conformation is a novel mechanism to explain the known anti-inflammatory effects of this compound, in particular because this CR3 (zeige ITGAM Antikörper) conformation is found in pro-inflammatory environments.

  5. CD18 methylation and age greater than 65 years were independent prognostic factors of thrombosis complicated by primary myelofibrosis.

  6. We found that LTbetaR polymorphisms caused severe BPH (zeige GLI3 Antikörper). Thus, LTbetaR may contribute to the risk of BPH (zeige GLI3 Antikörper) development.

  7. our study highlights the difficulties with the sole use of CD18 for the diagnosis of LAD-1 (zeige COL17A1 Antikörper).

  8. Critical role of the Mac1 (zeige ITGAM Antikörper)/NOX2 (zeige CYBB Antikörper) pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration

  9. Contact-activated C3(H2O) is a novel ligand for CD11b/CD18 (zeige ITGAM Antikörper) that mediates platelet-PMN (zeige TBCE Antikörper) complex formation and the binding of platelet-derived microparticles to PMNs.

  10. The expression level of Mac-1 (zeige ITGAM Antikörper) correlated with the number of neutrophils in patients with serous, endometrioid and undifferentiated epithelial ovarian cancer.

Cow (Bovine) Integrin beta 2 (ITGB2) Interaktionspartner

  1. Identification of numerous variations in exonic and intronic regions within the ITGB2 gene in Bos taurus and indicus screened for bovine leukocyte adhesion deficiency.

  2. intramammarily administered lipopolysaccharides seem to play an important role in modulating L-selectin (zeige SELL Antikörper) and beta2 integrin expression on circulating bovine polymorphonuclear leukocytes

  3. A delay in apoptosis was demonstrated in CD18-deficient bovine neutrophils and this appeared to be closely associated with lowered signalling via [Ca2 (zeige CA2 Antikörper)+]i, diminished annexin V (zeige ANXA5 Antikörper) expression on the cell surface, and decreased caspase 3 (zeige CASP3 Antikörper) activity in lysates

  4. The I-EGF (zeige EGF Antikörper)-3 domain of bovine CD18 (amino acid residues 541-581) is critical for conferring species-specific susceptibility to Mannheimia haemolytica leukotoxin.

  5. These results clearly indicate that the bovine CD18 subunit of beta(2)-integrins is the functional receptor for M. haemolytica Lkt.[ruminant-specific leukotoxin]

  6. study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein (zeige ORM1 Antikörper) and inhibited the chemotaxis of monocytes

  7. Loss of CD18 is associated with bovine leukocyte adhesion deficiency.

  8. Intact signal peptide of CD18, the beta-subunit (zeige POLG Antikörper) of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin.

Pig (Porcine) Integrin beta 2 (ITGB2) Interaktionspartner

  1. CR3 (zeige ITGAM Antikörper) plays a cardinal (zeige CARD8 Antikörper) role in beta-glucan signalling in porcine neutrophils, while macrophages use a more diverse receptor array to detect and respond towards beta-glucans.

  2. The expression of zona pellucida glycoprotein 3 (zeige ZP3 Antikörper) and integrin beta-2 in oocytes after brilliant cresyl blue staining is reported.

  3. early CD18 downregulation is profitable for the host in a situation with an intense LPS (zeige IRF6 Antikörper) stimulus

  4. It is concluded that porcine CD18 is necessary to mediate A. pleuropneumoniae ApxIIIA toxin-induced leukolysis.

Goat Integrin beta 2 (ITGB2) Interaktionspartner

  1. Integrin CD11c (zeige ITGAX Antikörper)/CD18 alpha-chain (zeige FCGRT Antikörper) phosphorylation is functionally important.

Integrin beta 2 (ITGB2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Alternative names and synonyms associated with Integrin beta 2 (ITGB2)

  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2) Antikörper
  • integrin, beta 2 (ITGB2) Antikörper
  • integrin beta 2 (Itgb2) Antikörper
  • integrin, beta 2 (Itgb2) Antikörper
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (CD18) Antikörper
  • lymphotoxin B receptor (Ltbr) Antikörper
  • lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR) Antikörper
  • 2E6 Antikörper
  • AI256028 Antikörper
  • AI528527 Antikörper
  • CD18 Antikörper
  • D12S370 Antikörper
  • ITGB2 Antikörper
  • LAD Antikörper
  • LCAMB Antikörper
  • LFA-1 Antikörper
  • Lfa1 Antikörper
  • LT-BETA-R Antikörper
  • Ltar Antikörper
  • LTbetaR Antikörper
  • MAC-1 Antikörper
  • MF17 Antikörper
  • MFI7 Antikörper
  • TNF-R-III Antikörper
  • Tnfbr Antikörper
  • TNFCR Antikörper
  • TNFR-RP Antikörper
  • TNFR2-RP Antikörper
  • TNFR3 Antikörper
  • TNFRrp Antikörper
  • TNFRSF3 Antikörper

Bezeichner auf Proteinebene für ITGB2

integrin beta-2 , Mac-1 beta , cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , complement receptor C3 subunit beta , lymphocyte function associated antigen 1 , macrophage antigen-1 beta , CD18 leukocyte adhesion molecule , integrin beta 2 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) , macrophage antigen 1 (mac-1) beta subunit) , cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor) , complement receptor C3 beta-subunit , integrin beta chain, beta 2 , leukocyte cell adhesion molecule CD18 , leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C , CD18 subunit , Leu-CAM receptor , integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2) , integrin beta 2 subunit , Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , Complement receptor C3 subunit beta , Integrin beta-2 , antigen CD18 , integrin beta-2 chain , LT beta-R , LT-beta receptor , TNF receptor-related protein , lymphotoxin-beta receptor , tumor necrosis factor receptor superfamily member 3 , tumor necrosis factor receptor superfamily, member 3 , lymphotoxin B receptor , tumor necrosis factor C receptor , tumor necrosis factor receptor 2-related protein , tumor necrosis factor receptor type III

GENE ID SPEZIES
458607 Pan troglodytes
710577 Macaca mulatta
16414 Mus musculus
309684 Rattus norvegicus
3689 Homo sapiens
281877 Bos taurus
396943 Sus scrofa
396181 Gallus gallus
100861185 Capra hircus
494433 Ovis aries
17000 Mus musculus
4055 Homo sapiens
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