anti-Integrin beta 2 (ITGB2) Antikörper

Bezeichnung:
anti-Integrin beta 2 Antikörper (ITGB2)
Auf www.antikoerper-online.de finden Sie aktuell 676 Integrin beta 2 (ITGB2) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Integrin beta 2 Proteine (16) und Integrin beta 2 Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 711 Integrin beta 2 Produkte verfügbar.
Synonyme:
2E6, AI256028, AI528527, CD18, D12S370, ITGB2, LAD, LCAMB, LFA-1, Lfa1, LT-BETA-R, Ltar, LTbetaR, MAC-1, MF17, MFI7, TNF-R-III, Tnfbr, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRrp, TNFRSF3
Alle Antikörper anzeigen Gen GeneID UniProt
ITGB2 16414 P11835
ITGB2 309684  
ITGB2 3689 P05107

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Am meisten referenzierte anti-Integrin beta 2 Antikörper

  1. Human Monoclonal Integrin beta 2 Primary Antibody für Func, FACS - ABIN111902 : Drbal, Angelisová, Cerný, Hilgert, Horejsí: A novel anti-CD18 mAb recognizes an activation-related epitope and induces a high-affinity conformation in leukocyte integrins. in Immunobiology 2001 (PubMed)
    Zeige alle 9 Referenzen für 111902

  2. Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody für FACS, IHC (fro) - ABIN118151 : Trowbridge, Omary: Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. in The Journal of experimental medicine 1982 (PubMed)
    Zeige alle 5 Referenzen für 118151

  3. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody für FACS - ABIN118552 : Chabanne, Marchal, Kaplanski, Fournel, Magnol, Monier, Rigal: Screening of 78 monoclonal antibodies directed against human leukocyte antigens for cross-reactivity with surface markers on canine lymphocytes. in Tissue antigens 1994 (PubMed)
    Zeige alle 3 Referenzen für 118552

  4. Dog (Canine) Monoclonal Integrin beta 2 Primary Antibody für FACS - ABIN118555 : Bindon, Hale, Waldmann: Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies. in European journal of immunology 1988 (PubMed)
    Zeige alle 3 Referenzen für 118555

  5. Rat (Rattus) Monoclonal Integrin beta 2 Primary Antibody für FACS, IHC (fro) - ABIN120418 : Tamatani, Kotani, Miyasaka: Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. in European journal of immunology 1991 (PubMed)
    Zeige alle 2 Referenzen für 120418

  6. Human Polyclonal Integrin beta 2 Primary Antibody für IF, ELISA - ABIN1532556 : Kishimoto, OConnor, Lee, Roberts, Springer: Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. in Cell 1987 (PubMed)
    Zeige alle 2 Referenzen für 1532556

  7. Human Polyclonal Integrin beta 2 Primary Antibody für IF, ELISA - ABIN1531540 : Hattori, Fujiyama, Taylor, Watanabe, Yada, Park, Toyoda, Ishii, Totoki, Choi, Groner, Soeda, Ohki, Takagi, Sakaki, Taudien, Blechschmidt, Polley, Menzel, Delabar, Kumpf, Lehmann, Patterson, Reichwald et al.: The DNA sequence of human chromosome 21. ... in Nature 2000 (PubMed)
    Zeige alle 2 Referenzen für 1531540

  8. Human Monoclonal Integrin beta 2 Primary Antibody für FACS - ABIN111901 : Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells. in Blood 2001 (PubMed)

Weitere Antikörper gegen Integrin beta 2 Interaktionspartner

Mouse (Murine) Integrin beta 2 (ITGB2) Interaktionspartner

  1. lymphatic vessel expansion occurs in two distinct phases; the first wave of expansion is dependent on IL-7 (zeige IL7 Antikörper); the second phase, responsible for leukocyte exit from the glands, is regulated by lymphotoxin (zeige LTB Antikörper) (LT)betaR signaling

  2. both GDF-15 (zeige GDF15 Antikörper) and TGF-beta1 (zeige TGFB1 Antikörper) counteract chemokine (zeige CCL1 Antikörper)-induced integrin activation on neutrophils via the ALK-5 (zeige TGFBR1 Antikörper)/TGF-betaRII heterodimer.

  3. the Slam (zeige SLAMF1 Antikörper) locus has an overall inhibitory role during NK cell activation that is solely dependent on 2B4 (zeige CD244 Antikörper). This effect is influenced by cytokines and leads to suppression of LFA-1 (zeige ITGAL Antikörper) activity.

  4. Wild-type C57BL/6 mice with pristane-induced lupus developed a strong IFN signature, which was absent in immunoglobulin-deficient (muMT), C3(-/-) , and CD18(-/-) mice.

  5. Study suggest an important impact of NKT (zeige CTSL1 Antikörper) cells and postulate a critical function for LFA-1 (zeige ITGAL Antikörper) during processes of liver regeneration.

  6. NDR1 (zeige STK38 Antikörper) kinase, activated by the Rap1 (zeige TERF2IP Antikörper) signaling cascade through RAPL (zeige RASSF5 Antikörper) and Mst1 (zeige MST1 Antikörper)/Mst2 (zeige STK3 Antikörper), associated with and recruited kindlin-3 (zeige FERMT3 Antikörper) to the immunological synapses, which was required for high-affinity LFA-1 (zeige ITGAL Antikörper)/ICAM-1 (zeige ICAM1 Antikörper) binding.

  7. LTbetaR is essential for efficient liver regeneration and cooperates with TNFRp55 (zeige TNFRSF1A Antikörper) in this process. Differences in survival kinetics strongly suggest distinct functions for these two cytokine receptors in liver regeneration.

  8. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.

  9. Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 (zeige ITGAL Antikörper) activation and neutrophil arrest in vivo

  10. report that beta2 and alpha4 integrins use different RIAM (zeige APBB1IP Antikörper)-dependent and -independent pathways to undergo activation by talin

Human Integrin beta 2 (ITGB2) Interaktionspartner

  1. The single nucleotide polymorphism rs1143678 substitutes Pro(1146) for Ser (zeige SIGLEC1 Antikörper) in the integrin alphaM cytoplasmic tail generates a noncanonical 14-3-3zeta (zeige YWHAZ Antikörper) binding site that modulates integrin alphaM(PS)beta2 outside-in signaling

  2. this study shows that cross-talk between LFA-1 (zeige ITGAL Antikörper) and Notch1 (zeige NOTCH1 Antikörper) through the Akt (zeige AKT1 Antikörper)/ERK (zeige EPHB2 Antikörper)-GSK3beta (zeige GSK3b Antikörper) signaling enhances T cell differentiation toward Th1 (zeige TH1L Antikörper)

  3. FRbeta (zeige FOLR2 Antikörper) as a novel CD11b/CD18 (zeige ITGAM Antikörper) regulator for trafficking and homing of a subset of macrophages on collagen.

  4. The results show that with LFA-1 (zeige ITGAL Antikörper) antibodies, we can activate LFA-1 (zeige ITGAL Antikörper) and inhibit alpha4beta1, inhibit both LFA-1 (zeige ITGAL Antikörper) and alpha4beta1, inhibit LFA-1 (zeige ITGAL Antikörper) but not alpha4beta1, or not affect LFA-1 (zeige ITGAL Antikörper) or alpha4beta1

  5. K152 and D120 within the PH domain of SKAP55 (zeige SKAP1 Antikörper) regulate plasma membrane targeting and T cell receptor-mediated activation of LFA-1 (zeige ITGAL Antikörper).

  6. LIGHT and LTBR (zeige LTBR Antikörper) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.

  7. Genetic inactivation and blockade studies revealed that homophilic interactions between intercellular adhesion molecule 1 (ICAM-1 (zeige ICAM1 Antikörper)) expressed on tumor cells and MSCs, respectively, regulate the competition between tumor cells and HSPCs for binding to MSCs. Moreover, tumor cell-secreted soluble ICAM-1 (zeige ICAM1 Antikörper)(sICAM-1) also impaired HSPC (zeige PSMA7 Antikörper) adhesion via blocking CD18-ICAM-1 (zeige ICAM1 Antikörper) binding between HSPCs and MSCs

  8. The ability of simvastatin to target CR3 (zeige ITGAM Antikörper) in its ligand binding-activated conformation is a novel mechanism to explain the known anti-inflammatory effects of this compound, in particular because this CR3 (zeige ITGAM Antikörper) conformation is found in pro-inflammatory environments.

  9. CD18 methylation and age greater than 65 years were independent prognostic factors of thrombosis complicated by primary myelofibrosis.

  10. We found that LTbetaR polymorphisms caused severe BPH (zeige GLI3 Antikörper). Thus, LTbetaR may contribute to the risk of BPH (zeige GLI3 Antikörper) development.

Cow (Bovine) Integrin beta 2 (ITGB2) Interaktionspartner

  1. Identification of numerous variations in exonic and intronic regions within the ITGB2 gene in Bos taurus and indicus screened for bovine leukocyte adhesion deficiency.

  2. intramammarily administered lipopolysaccharides seem to play an important role in modulating L-selectin (zeige SELL Antikörper) and beta2 integrin expression on circulating bovine polymorphonuclear leukocytes

  3. A delay in apoptosis was demonstrated in CD18-deficient bovine neutrophils and this appeared to be closely associated with lowered signalling via [Ca2 (zeige CA2 Antikörper)+]i, diminished annexin V (zeige ANXA5 Antikörper) expression on the cell surface, and decreased caspase 3 (zeige CASP3 Antikörper) activity in lysates

  4. The I-EGF (zeige EGF Antikörper)-3 domain of bovine CD18 (amino acid residues 541-581) is critical for conferring species-specific susceptibility to Mannheimia haemolytica leukotoxin.

  5. These results clearly indicate that the bovine CD18 subunit of beta(2)-integrins is the functional receptor for M. haemolytica Lkt.[ruminant-specific leukotoxin]

  6. study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein (zeige ORM1 Antikörper) and inhibited the chemotaxis of monocytes

  7. Loss of CD18 is associated with bovine leukocyte adhesion deficiency.

  8. Intact signal peptide of CD18, the beta-subunit (zeige POLG Antikörper) of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin.

Pig (Porcine) Integrin beta 2 (ITGB2) Interaktionspartner

  1. CR3 (zeige ITGAM Antikörper) plays a cardinal (zeige CARD8 Antikörper) role in beta-glucan signalling in porcine neutrophils, while macrophages use a more diverse receptor array to detect and respond towards beta-glucans.

  2. The expression of zona pellucida glycoprotein 3 (zeige ZP3 Antikörper) and integrin beta-2 in oocytes after brilliant cresyl blue staining is reported.

  3. early CD18 downregulation is profitable for the host in a situation with an intense LPS (zeige IRF6 Antikörper) stimulus

  4. It is concluded that porcine CD18 is necessary to mediate A. pleuropneumoniae ApxIIIA toxin-induced leukolysis.

Goat Integrin beta 2 (ITGB2) Interaktionspartner

  1. Integrin CD11c (zeige ITGAX Antikörper)/CD18 alpha-chain (zeige FCGRT Antikörper) phosphorylation is functionally important.

Integrin beta 2 (ITGB2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Alternative names and synonyms associated with Integrin beta 2 (ITGB2)

  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2) Antikörper
  • integrin, beta 2 (ITGB2) Antikörper
  • integrin beta 2 (Itgb2) Antikörper
  • integrin, beta 2 (Itgb2) Antikörper
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (CD18) Antikörper
  • lymphotoxin B receptor (Ltbr) Antikörper
  • lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR) Antikörper
  • 2E6 Antikörper
  • AI256028 Antikörper
  • AI528527 Antikörper
  • CD18 Antikörper
  • D12S370 Antikörper
  • ITGB2 Antikörper
  • LAD Antikörper
  • LCAMB Antikörper
  • LFA-1 Antikörper
  • Lfa1 Antikörper
  • LT-BETA-R Antikörper
  • Ltar Antikörper
  • LTbetaR Antikörper
  • MAC-1 Antikörper
  • MF17 Antikörper
  • MFI7 Antikörper
  • TNF-R-III Antikörper
  • Tnfbr Antikörper
  • TNFCR Antikörper
  • TNFR-RP Antikörper
  • TNFR2-RP Antikörper
  • TNFR3 Antikörper
  • TNFRrp Antikörper
  • TNFRSF3 Antikörper

Bezeichner auf Proteinebene für ITGB2

integrin beta-2 , Mac-1 beta , cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , complement receptor C3 subunit beta , lymphocyte function associated antigen 1 , macrophage antigen-1 beta , CD18 leukocyte adhesion molecule , integrin beta 2 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1 , integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) , macrophage antigen 1 (mac-1) beta subunit) , cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor) , complement receptor C3 beta-subunit , integrin beta chain, beta 2 , leukocyte cell adhesion molecule CD18 , leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C , CD18 subunit , Leu-CAM receptor , integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2) , integrin beta 2 subunit , Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta , Complement receptor C3 subunit beta , Integrin beta-2 , antigen CD18 , integrin beta-2 chain , LT beta-R , LT-beta receptor , TNF receptor-related protein , lymphotoxin-beta receptor , tumor necrosis factor receptor superfamily member 3 , tumor necrosis factor receptor superfamily, member 3 , lymphotoxin B receptor , tumor necrosis factor C receptor , tumor necrosis factor receptor 2-related protein , tumor necrosis factor receptor type III

GENE ID SPEZIES
458607 Pan troglodytes
710577 Macaca mulatta
16414 Mus musculus
309684 Rattus norvegicus
3689 Homo sapiens
281877 Bos taurus
396943 Sus scrofa
396181 Gallus gallus
100861185 Capra hircus
494433 Ovis aries
17000 Mus musculus
4055 Homo sapiens
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