EGF Proteine (EGF)

Bezeichnung:
Epidermal Growth Factor Proteine (EGF)
Auf www.antikoerper-online.de finden Sie aktuell 159 Epidermal Growth Factor (EGF) Proteine von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen EGF Antikörper (523) und EGF Kits (139) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 836 EGF Produkte verfügbar.
Synonyme:
AI790464, CEGF, HOMG4, URG
alle Proteine anzeigen Gen GeneID UniProt
EGF 25313 P07522
EGF 1950 P01133
EGF 13645 P01132

Weitere Synonyme anzeigen

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Am meisten referenzierte EGF Proteine

  1. Mouse (Murine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666932 : Henson, Gibson: Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy. in Cellular signalling 2006 (PubMed)
    Zeige alle 5 Referenzen für 2666932

  2. Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666930 : Barnes: Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. in The Journal of cell biology 1982 (PubMed)
    Zeige alle 5 Referenzen für 2666930

  3. Mouse (Murine) EGF Protein expressed in Yeast - ABIN2007864 : Dreux, Lamb, Modjtahedi, Ferns: The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. in Atherosclerosis 2006 (PubMed)
    Zeige alle 5 Referenzen für 2007864

  4. Mouse (Murine) EGF Protein expressed in Human Cells - ABIN2007863 : Carpenter, Cohen: Epidermal growth factor. in The Journal of biological chemistry 1990 (PubMed)
    Zeige alle 3 Referenzen für 2007863

  5. Dog (Canine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2008847 : Hommel, Harvey, Driscoll, Campbell: Human epidermal growth factor. High resolution solution structure and comparison with human transforming growth factor alpha. in Journal of molecular biology 1992 (PubMed)
    Zeige alle 3 Referenzen für 2008847

  6. Mouse (Murine) EGF Protein expressed in Human Cells - ABIN2007859 : Goodsell: The molecular perspective: epidermal growth factor. in Stem cells (Dayton, Ohio) 2003 (PubMed)
    Zeige alle 3 Referenzen für 2007859

  7. Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2452188 : Cohen, Carpenter: Human epidermal growth factor: isolation and chemical and biological properties. in Proceedings of the National Academy of Sciences of the United States of America 1975 (PubMed)
    Zeige alle 2 Referenzen für 2452188

  8. Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN593405 : An, Gip, Kim, Wu, Park, McVaugh, Schaffer, Bertozzi, Lebrilla: Extensive determination of glycan heterogeneity reveals an unusual abundance of high mannose glycans in enriched plasma membranes of human embryonic stem cells. in Molecular & cellular proteomics : MCP 2012 (PubMed)
    Zeige alle 2 Referenzen für 593405

  9. Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2215428 : Zhou, Zhang, Jin, Chen, Wu, Li, Yue, Luo, Wang: Prokaryotic expression and refolding of EGFR extracellular domain and generation of phage display human scFv against EGFR. in Biomedicine & pharmacotherapy 2013 (PubMed)

Weitere Proteine zu EGF Interaktionspartnern

Zebrafish Epidermal Growth Factor (EGF) Interaktionspartner

  1. Zebrafish scube1 (zeige SCUBE1 Proteine) (signal peptide-CUB (complement protein C1r (zeige C1R Proteine)/C1s (zeige C1S Proteine), Uegf, and Bmp1 (zeige BMP1 Proteine))-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis

  2. EGF is likely a potential paracrine/juxtacrine factor from the oocytes to regulate the function of the follicle cells.

  3. These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.

Human Epidermal Growth Factor (EGF) Interaktionspartner

  1. EGF-induced, calpain-mediated proteolysis contributes to the rapid destruction of cyclin G2 and that the PEST domain is critical for EGF/calpain actions

  2. The salivary levels of EGF are significantly increased during the acute phase of natural rotavirus infection.

  3. findings have identified a role for members of these signaling pathways in the regulation of EGF-induced vimentin (zeige VIM Proteine) expression in the MDA-MB-468 breast cancer cell line

  4. miR (zeige MLXIP Proteine)-223 downregulated the local expression of epidermal growth factor (EGF), leading to decreased activation of EGF receptor (EGFR (zeige EGFR Proteine)) on target cells and, eventually, dampening a positive EGF-EGFR (zeige EGFR Proteine) autocrine/paracrine stimulation loop induced by the post-surgical wound-healing response.

  5. EGFR (zeige EGFR Proteine) and EGF expression showed no significant difference between placentas from normal pregnancies and those complicated with preeclampsia.

  6. Atomistic molecular dynamics simulations show that N-glycosylation of the EGFR (zeige EGFR Proteine) extracellular domain plays critical roles in the binding of growth factors, monoclonal antibodies, and the dimeric partners to the monomeric EGFR (zeige EGFR Proteine) extracellular domain.

  7. CMTM3 (zeige CMTM3 Proteine) decreases EGFR (zeige EGFR Proteine) expression, facilitates EGFR (zeige EGFR Proteine) degradation, and inhibits the EGF-mediated tumorigenicity of gastric cancer cells by enhancing Rab5 (zeige RAB5A Proteine) activity.

  8. Findings suggest EGF not only promotes the proliferation of adipose stem cells and delays their senescence, but also maintains the differentiation potency of adipose stem cells, which are related to the EGF-induced activation of STAT (zeige STAT1 Proteine) signal pathway.

  9. The results show that the interaction between STS-1 (zeige STS1 Proteine) and ShcA (zeige SHC1 Proteine) is regulated in response to EGF receptor (zeige EGFR Proteine) activation.

  10. Insulin (zeige INS Proteine) treatment caused sustained Akt (zeige AKT1 Proteine) activity, whereas EGF or PDGF (zeige PDGFA Proteine)-AA promoted transient signaling; PDGF (zeige PDGFA Proteine)-BB produced sustained responses at higher concentrations.Transient responses to EGF were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (zeige IGF1 Proteine) caused full Akt (zeige AKT1 Proteine) activation

Mouse (Murine) Epidermal Growth Factor (EGF) Interaktionspartner

  1. These results indicate that Kindlin-1 (zeige FERMT1 Proteine) is essential in EGF-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF in the treatment of acute wounds.

  2. concentration of EGF is critical for the switch between hair follicle growth and inhibition, and EGF promotes DP cell proliferation via Notch (zeige NOTCH1 Proteine) signaling pathway

  3. EGF promotes FoxM1 (zeige FOXM1 Proteine) expression through the ERK (zeige EPHB2 Proteine) signal pathway

  4. Data indicate that Sonic hedgehog (Shh (zeige SHH Proteine)) stimulate branching morphogenesis (BrM (zeige SMARCA2 Proteine)) and induced synthesis of mRNAs for Ptch1 (zeige PTCH1 Proteine) protein, epidermal growth factor (EGF) and receptors of the ErbB (zeige EGFR Proteine) receptors ErbB1 (zeige EGFR Proteine), ErbB2 (zeige ERBB2 Proteine) and ErbB3 (zeige ERBB3 Proteine).

  5. Either LIF (zeige LIF Proteine) or EGF is needed during development of pre-implantation embryo.

  6. PXR (zeige NR1I2 Proteine) activation stimulates EGF-mediated hepatocyte proliferation in mice, at least in part, through inhibiting FOXO3 (zeige FOXO3 Proteine) from accelerating cell-cycle progression.

  7. Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (zeige EGFR Proteine) signaling.

  8. modulation of EGF signaling affects in vitro expansion and differentiation of progenitors from embryonic pancreas of both mice and man.

  9. TLR4 (zeige TLR4 Proteine) blockade prevented TPN (zeige TAPBP Proteine)-associated intestinal mucosa atrophy by preserving proliferation and preventing apoptosis. This is driven by a reduction in TNF-alpha (zeige TNF Proteine) abundance and increased EGF.

  10. EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 (zeige GATA4 Proteine) in a time- and dose-dependent manner.

Pig (Porcine) Epidermal Growth Factor (EGF) Interaktionspartner

  1. Interval between litters and litter size may be linked with EGF polymorphisms in pigs.

  2. 10 nM/L EGF was the optimal dose for serum-free culture, which can replace traditional standard serum medium for in vitro expansion of miniature pig bone marrow-derived mesenchymal stem cells.

  3. EGF coordinately activates multiple cell signaling pathways critical to proliferation, migration and survival of trophectoderm cells.

  4. progesterone-induced TACE/ADAM17 (zeige ADAM17 Proteine) leads to production of soluble EGF domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes

  5. The phase-related expression of EGF and EGFR (zeige EGFR Proteine) in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF and its receptor on the uterine artery and the region supplying these vessels.

  6. EGF appears to sensitize epithelial cells to the detrimental effects of IFN-alpha (zeige IFNA Proteine) but also helps to restore barrier function in the healing phase.

Cow (Bovine) Epidermal Growth Factor (EGF) Interaktionspartner

  1. analysis of EGF in dairy cows reveals increased EGF concentrations for 2-3 days between Days 2 and 5

  2. Data suggest that EGF expression in endometrium varies by species and parity; in Japanese Black cows, EGF expression is consistently high, while in Holstein cows, EGF expression is down-regulated in postpartum period after second calving.

  3. Data suggest that epidermal growth factor receptor (zeige EGFR Proteine) B [ErbB (zeige EGFR Proteine)] isoforms and their ligands (epidermal growth factor [EGF], amphiregulin (zeige AREG Proteine) [AREG (zeige AREG Proteine)], and neuregulin-1 (zeige NRG1 Proteine) [NRG1 (zeige NRG1 Proteine)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.

  4. EGF plays a role during bovine placentation.

  5. Data suggest that epidermal growth factor (EGF) and EGF receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.

EGF Protein Überblick

Protein Überblick

This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with EGF

  • epidermal growth factor (EGF)
  • epidermal growth factor (egf)
  • pro-epidermal growth factor (CpipJ_CPIJ020278)
  • epidermal growth factor (Egf)
  • epidermal growth factor (LOC100008808)
  • AI790464 Protein
  • CEGF Protein
  • HOMG4 Protein
  • URG Protein

Bezeichner auf Proteinebene für Epidermal Growth Factor Proteine (EGF)

epidermal growth factor (beta-urogastrone) , pro-epidermal growth factor , beta-urogastrone , Pro-epidermal growth factor precursor (EGF)

GENE ID SPEZIES
461435 Pan troglodytes
698619 Macaca mulatta
100218747 Taeniopygia guttata
403045 Danio rerio
6054699 Culex quinquefasciatus
25313 Rattus norvegicus
1950 Homo sapiens
13645 Mus musculus
408035 Gallus gallus
100714471 Cavia porcellus
100008808 Oryctolagus cuniculus
397083 Sus scrofa
403657 Canis lupus familiaris
530315 Bos taurus
493978 Felis catus
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