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Mouse (Murine) EGF Protein expressed in Yeast - ABIN2007864
Dreux, Lamb, Modjtahedi, Ferns: The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. in Atherosclerosis 2006
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Mouse (Murine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666932
Henson, Gibson: Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy. in Cellular signalling 2006
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Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666930
Barnes: Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. in The Journal of cell biology 1982
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Rat (Rattus) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2009632
Carpenter, Cohen: Epidermal growth factor. in The Journal of biological chemistry 1990
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Mouse (Murine) EGF Protein expressed in Human Cells - ABIN2007863
Hommel, Harvey, Driscoll, Campbell: Human epidermal growth factor. High resolution solution structure and comparison with human transforming growth factor alpha. in Journal of molecular biology 1992
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Dog (Canine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2008847
Goodsell: The molecular perspective: epidermal growth factor. in Stem cells (Dayton, Ohio) 2003
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Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2452188
Cohen, Carpenter: Human epidermal growth factor: isolation and chemical and biological properties. in Proceedings of the National Academy of Sciences of the United States of America 1975
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Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2215428
Zhou, Zhang, Jin, Chen, Wu, Li, Yue, Luo, Wang: Prokaryotic expression and refolding of EGFR extracellular domain and generation of phage display human scFv against EGFR. in Biomedicine & pharmacotherapy 2013
Zebrafish scube1 (zeige SCUBE1 Proteine) (signal peptide-CUB (complement protein C1r (zeige C1R Proteine)/C1s (zeige C1S Proteine), Uegf, and Bmp1 (zeige BMP1 Proteine))-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis
EGF is likely a potential paracrine/juxtacrine factor from the oocytes to regulate the function of the follicle cells.
These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.
Subgroup analysis in a Slovak population by gender showed the genotype EGF G61G and allele G was associated with non significantly increased risk of MDD.
EGF G1380A SNP was associated with the susceptibility and prognosis of malignant melanoma.
Therefore, EGF is suggested to induce E-cadherin (zeige CDH1 Proteine) down-regulation at the transcriptional level through the MEK (zeige MAP2K1 Proteine)/ERK (zeige EPHB2 Proteine) pathway, which might result in, at least in part, the induction of cellular morphological changes and cell migration in LoVo cells.
EGF and insulin receptor tyrosine kinase exemplify how receptor location is coupled to signal transduction. (Review)
These results indicate that Kindlin-1 (zeige FERMT1 Proteine) is essential in EGF-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF in the treatment of acute wounds.
angiopoietin-like 4 (zeige ANGPTL4 Proteine) plays an important role in the regulation of epidermal growth factor induced cancer metastasis
EGF/MCP-1 (zeige CCL2 Proteine) ratio is independently associated with severity of tubular atrophy and interstitial fibrosis in primary glomerulonephritis, but the ability of EGF/MCP-1 (zeige CCL2 Proteine) ratio to discriminate moderate to severe IFTA may not be much better than EGF alone.
SMOC binds to Pro-EGF, but does not induce Erk (zeige EPHB2 Proteine) phosphorylation via the EGFR (zeige EGFR Proteine).
findings indicate that the effects of stimulation with EGF, HGF (zeige HGF Proteine) and TGFbeta (zeige TGFB1 Proteine) on melanoma cell invasiveness could depend on melanoma cell progression stage.
Epidermal Growth Factor polymorphisms are associated with increased rate of sustained virological response.
concentration of EGF is critical for the switch between hair follicle growth and inhibition, and EGF promotes DP cell proliferation via Notch (zeige NOTCH1 Proteine) signaling pathway
EGF promotes FoxM1 (zeige FOXM1 Proteine) expression through the ERK (zeige EPHB2 Proteine) signal pathway
Data indicate that Sonic hedgehog (Shh (zeige SHH Proteine)) stimulate branching morphogenesis (BrM (zeige SMARCA2 Proteine)) and induced synthesis of mRNAs for Ptch1 (zeige PTCH1 Proteine) protein, epidermal growth factor (EGF) and receptors of the ErbB (zeige EGFR Proteine) receptors ErbB1 (zeige EGFR Proteine), ErbB2 (zeige ERBB2 Proteine) and ErbB3 (zeige ERBB3 Proteine).
Either LIF (zeige LIF Proteine) or EGF is needed during development of pre-implantation embryo.
PXR (zeige NR1I2 Proteine) activation stimulates EGF-mediated hepatocyte proliferation in mice, at least in part, through inhibiting FOXO3 (zeige FOXO3 Proteine) from accelerating cell-cycle progression.
Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (zeige EGFR Proteine) signaling.
modulation of EGF signaling affects in vitro expansion and differentiation of progenitors from embryonic pancreas of both mice and man.
TLR4 (zeige TLR4 Proteine) blockade prevented TPN (zeige TAPBP Proteine)-associated intestinal mucosa atrophy by preserving proliferation and preventing apoptosis. This is driven by a reduction in TNF-alpha (zeige TNF Proteine) abundance and increased EGF.
EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 (zeige GATA4 Proteine) in a time- and dose-dependent manner.
Interval between litters and litter size may be linked with EGF polymorphisms in pigs.
10 nM/L EGF was the optimal dose for serum-free culture, which can replace traditional standard serum medium for in vitro expansion of miniature pig bone marrow-derived mesenchymal stem cells.
EGF coordinately activates multiple cell signaling pathways critical to proliferation, migration and survival of trophectoderm cells.
progesterone-induced TACE/ADAM17 (zeige ADAM17 Proteine) leads to production of soluble EGF domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes
The phase-related expression of EGF and EGFR (zeige EGFR Proteine) in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF and its receptor on the uterine artery and the region supplying these vessels.
EGF appears to sensitize epithelial cells to the detrimental effects of IFN-alpha (zeige IFNA Proteine) but also helps to restore barrier function in the healing phase.
analysis of EGF in dairy cows reveals increased EGF concentrations for 2-3 days between Days 2 and 5
Data suggest that EGF expression in endometrium varies by species and parity; in Japanese Black cows, EGF expression is consistently high, while in Holstein cows, EGF expression is down-regulated in postpartum period after second calving.
Data suggest that epidermal growth factor receptor (zeige EGFR Proteine) B [ErbB (zeige EGFR Proteine)] isoforms and their ligands (epidermal growth factor [EGF], amphiregulin (zeige AREG Proteine) [AREG (zeige AREG Proteine)], and neuregulin-1 (zeige NRG1 Proteine) [NRG1 (zeige NRG1 Proteine)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.
EGF plays a role during bovine placentation.
Data suggest that epidermal growth factor (EGF) and EGF receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
epidermal growth factor (beta-urogastrone)
, pro-epidermal growth factor
, Pro-epidermal growth factor precursor (EGF)