anti-DUSP6 (DUSP6) Antikörper

Bezeichnung:
anti-Dual Specificity Phosphatase 6 Antikörper (DUSP6)
Auf www.antikoerper-online.de finden Sie aktuell 126 Dual Specificity Phosphatase 6 (DUSP6) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DUSP6 Proteine (7) und DUSP6 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 146 DUSP6 Produkte verfügbar.
Synonyme:
1300019I03Rik, dusp6, fd19d04, HH19, MKP-3, MKP3, PYST1, wu:fd19d04, wu:fd99d09, zgc:55957, zgc:77211

Meistgesuchte Reaktivitäten zu anti-DUSP6 (DUSP6) Antikörper

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anti-Human DUSP6 Antikörper:

anti-Mouse (Murine) DUSP6 Antikörper:

anti-Rat (Rattus) DUSP6 Antikörper:

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Am meisten referenzierte anti-DUSP6 Antikörper

  1. Human Polyclonal DUSP6 Primary Antibody für EIA, WB - ABIN360781 : Furukawa, Fujisaki, Yoshida, Kanai, Sunamura, Abe, Takeda, Matsuno, Horii: Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 (PubMed)
    Zeige alle 5 Referenzen für 360781

  2. Human Monoclonal DUSP6 Primary Antibody für IF, IHC (p) - ABIN560670 : Okudela, Yazawa, Woo, Sakaeda, Ishii, Mitsui, Shimoyamada, Sato, Tajiri, Ogawa, Masuda, Takahashi, Sugimura, Kitamura: Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis. in The American journal of pathology 2009 (PubMed)
    Zeige alle 3 Referenzen für 560670

  3. Rat (Rattus) Polyclonal DUSP6 Primary Antibody für FACS, WB - ABIN1882185 : Muda, Boschert, Dickinson, Martinou, Martinou, Camps, Schlegel, Arkinstall: MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase. in The Journal of biological chemistry 1996 (PubMed)
    Zeige alle 3 Referenzen für 1882185

  4. Human Polyclonal DUSP6 Primary Antibody für ELISA, WB - ABIN4334835 : Geetha, Mihaly, Stockenhuber, Blasi, Uhrin, Binder, Freissmuth, Breuss et al.: Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of ... in The Journal of biological chemistry 2011 (PubMed)

Weitere Antikörper gegen DUSP6 Interaktionspartner

Zebrafish Dual Specificity Phosphatase 6 (DUSP6) Interaktionspartner

  1. Lef1 (zeige LEF1 Antikörper) has a role in regulating Dusp6 in formation of the zebrafish posterior lateral line primordium

  2. During fin development, dusp6, a known MAPK/ERK (zeige MAPK1 Antikörper) regulator, is induced in the mesoderm by FGF8 (zeige FGF8 Antikörper) signaling, through the PI3 (zeige PI3 Antikörper)/Akt (zeige AKT1 Antikörper) pathway.

  3. During fin development, dusp6, a known MAPK/ERK (zeige MAPK1 Antikörper) regulator, is induced in the mesoderm by FGF8 (zeige FGF8 Antikörper) signaling, through the PI3 (zeige PI3 Antikörper)/Akt (zeige AKT1 Antikörper) pathway.

  4. Mkp3 encodes a feedback attenuator of the FGF pathway, the expression of which is initiated at an early stage so as to ensure correct FGF signaling levels at the time of axial patterning.

Xenopus laevis Dual Specificity Phosphatase 6 (DUSP6) Interaktionspartner

  1. Retinoic acid-dependent control of MAP kinase phosphatase-3 is necessary for early kidney development.

Human Dual Specificity Phosphatase 6 (DUSP6) Interaktionspartner

  1. PICSAR has a role in promoting cSCC (zeige CYP11A1 Antikörper) progression via activation of extracellular signal-regulated kinase 1/2 (zeige MAPK3 Antikörper) signaling pathway by downregulating DUSP6 expression

  2. DUSP6 rs2279574 SNPs was not associated with chemoradiotherapy response, whereas tumor regression, weight loss, clinical stage, and cigarette smoking were independent prognostic predictors for these Chinese patients with non-small cell lung cancer.

  3. DNA samples from each patient were genotyped for DUSP6 and TOP2A (zeige TOP2A Antikörper) SNPs

  4. Suppression of the FOXA1 (zeige FOXA1 Antikörper)/DUSP6 signaling pathway may contribute to the development of Hirschsprung disease.

  5. These observations led us to conclude that increased TSH signaling overcomes OIS and is essential for B-RafV600E-induced papillary thyroid carcinogenesis.

  6. Dusp6 expression was higher in progestin-sensitive atypical endometrial hyperplasia groups compared with progestin-resistant groups. After treatment, Dusp6 expression was upregulated in progestin-sensitive groups, but not in progestin-resistant groups.

  7. Our results suggest that DUSP6 gene expression in tumour samples may be a prognostic marker in NSCLC

  8. DUSP6 downregulated the expression of matrix metallopeptidase 3 (zeige MMP3 Antikörper).

  9. These results therefore indicate that p53 (zeige TP53 Antikörper)-mediated up-regulation of MKP-3 contributes to the establishment of the senescent cellular phenotype through dephosphorylating ERK1/2 (zeige MAPK1/3 Antikörper)

  10. Downregulation of Dusp6, Sprouty4 (zeige SPRY4 Antikörper), and Sef (zeige TFCP2 Antikörper)--negative modulators of FGF2 (zeige FGF2 Antikörper)/ERK1/2 (zeige MAPK1/3 Antikörper) signaling--was present in eutopic endometria of adenomyosis, which may play critical roles in the development of adenomyosis.

Mouse (Murine) Dual Specificity Phosphatase 6 (DUSP6) Interaktionspartner

  1. this study shows that CCL2 (zeige CCL2 Antikörper) supports the classical activation of macrophages, with miR (zeige MLXIP Antikörper)-9 mediated down-regulation of Dusp6 and enhanced ERK (zeige EPHB2 Antikörper)-mediated signal transduction possibly mediating this enhanced pro-inflammatory gene expression

  2. Mitogen-activated protein kinase phosphatase 3 upregulation requires the activation of the Erk1/2 (zeige MAPK1/3 Antikörper) pathway, which correlates with the shutdown of this pathway.

  3. MKP3 could be an important factor in the regulation of brown adipocyte differentiation.

  4. DUSP6 regulates CD4 (zeige CD4 Antikörper)+ T-cell activation and differentiation by inhibiting the TCR-dependent ERK1/2 (zeige MAPK1/3 Antikörper) activation and restraining spontaneous colitis in IL-10 (zeige IL10 Antikörper)-deficient mice.

  5. exercised obese mice had a lower expression of MKP-3 and FoxO1 (zeige FOXO1 Antikörper)/MKP-3 association in the liver

  6. c-Myb (zeige MYB Antikörper) plays an important role in H-Ras (zeige HRAS Antikörper)-induced MKP-3 transcription

  7. Mice lacking MKP-3 protein develop an abnormal persistent state of mechanical allodynia following plantar incision, concurrent with long-lasting spinal phosphorylation of ERK-1 (zeige MAPK3 Antikörper)/2 and p38 (zeige CRK Antikörper).

  8. Depletion of DUSP6 reduced the viability of cancer cell lines and increased the cytotoxicity of EGFR (zeige EGFR Antikörper) and other targeted inhibitors, and cytotoxic agents.

  9. LH/hCG (zeige CGA Antikörper) tightly up-regulates MKP-3 which in turn, dephosphorylates ERK1/2 (zeige MAPK1/3 Antikörper) and drives p21 (zeige D4S234E Antikörper) expression.

  10. dual specificity phosphatases (Dusps) 6 and 14 are up-regulated by activation of beta-catenin (zeige CTNNB1 Antikörper) in murine liver cells

DUSP6 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with DUSP6

  • dual specificity phosphatase 7 (dusp7) Antikörper
  • dual specificity phosphatase 6 (dusp6) Antikörper
  • dual specificity phosphatase 6 (DUSP6) Antikörper
  • dual specificity phosphatase 6 (LOC100222847) Antikörper
  • Dual specificity protein phosphatase 6 (dus6) Antikörper
  • dual specificity phosphatase 6 (Dusp6) Antikörper
  • 1300019I03Rik Antikörper
  • dusp6 Antikörper
  • fd19d04 Antikörper
  • HH19 Antikörper
  • MKP-3 Antikörper
  • MKP3 Antikörper
  • PYST1 Antikörper
  • wu:fd19d04 Antikörper
  • wu:fd99d09 Antikörper
  • zgc:55957 Antikörper
  • zgc:77211 Antikörper

Bezeichner auf Proteinebene für DUSP6

dual specificity phosphatase 6 , dual specificity protein phosphatase 7 , dual specificity protein phosphatase 6 , etID14116.25 , MAP kinase phosphatase X17C , Dual specificity protein phosphatase 6 , dual specificity protein phosphatase 6-like , MAP kinase phosphatase 3 , dual specificity protein phosphatase PYST1 , mitogen-activated protein kinase phosphatase 3 , serine/threonine specific protein phosphatase , MKP-3

GENE ID SPEZIES
327246 Danio rerio
353314 Danio rerio
374272 Gallus gallus
398829 Xenopus laevis
452115 Pan troglodytes
733815 Xenopus (Silurana) tropicalis
100137150 Takifugu rubripes
100222847 Taeniopygia guttata
100306828 Salmo salar
100409879 Callithrix jacchus
100466694 Ailuropoda melanoleuca
100051565 Equus caballus
100136684 Oncorhynchus mykiss
100460800 Pongo abelii
100588912 Nomascus leucogenys
1848 Homo sapiens
67603 Mus musculus
116663 Rattus norvegicus
515310 Bos taurus
482594 Canis lupus familiaris
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