Septin 3 Proteine (SEPT3)

Septin 3 Proteine (SEPT3)
Auf finden Sie aktuell 15 Septin 3 (SEPT3) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Septin 3 Antikörper (65) und Septin 3 Kits (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 100 Septin 3 Produkte verfügbar.
3110018K01Rik, 4930471M23Rik, 5730478O19Rik, ANT2BP, AV154067, B530002E20Rik, bK250D10.3, GEF, GEF-H1, GEFH1, LFP40, MGC69255, P40, Sep-03, Sep3, sept3, Tango9, zgc:110051
alle Proteine anzeigen Gen GeneID UniProt
SEPT3 9181 Q92974
SEPT3 24050 Q9Z1S5
SEPT3 56003 Q9WU34

Weitere Synonyme anzeigen

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Weitere Proteine zu Septin 3 Interaktionspartnern

Human Septin 3 (SEPT3) Interaktionspartner

  1. depletion induces phosphorylation of the microtubule-associated GEF-H1 on Ser886, and thereby promotes RhoA activity and actin stress fiber assembly.

  2. human brain malformation is recapitulated in Arhgef2 (zeige ARHGEF2 Proteine) mutant mice and identify an aberrant migration of distinct components of the precerebellar system as a pathomechanism underlying the midbrain-hindbrain phenotype. Our results highlight the crucial function of ARHGEF2 (zeige ARHGEF2 Proteine) in human brain development and identify a mutation in ARHGEF2 (zeige ARHGEF2 Proteine) as novel cause of a neurodevelopmental disorder.

  3. Overexpression of miR (zeige MLXIP Proteine)-194 downregulates the GEF-H1 (zeige ARHGEF2 Proteine)/RhoA (zeige RHOA Proteine) pathway, inhibits melanoma cancer cell proliferation and metastasis. Furthermore, miR (zeige MLXIP Proteine)-194 expression is negatively associated with tumor-node-metastasis (TNM (zeige ODZ1 Proteine)) stages

  4. data suggest that the induction of SGK1 (zeige SGK1 Proteine) through treatment with dexamethasone alters MT dynamics to increase Sec5-GEF-H1 (zeige ARHGEF2 Proteine) interactions, which promote GEF-H1 (zeige ARHGEF2 Proteine) targeting to adhesion sites.

  5. this study reports the crystal structure of human GEF-H1 (zeige ARHGEF2 Proteine) PH domain to 2.45 A resolution.

  6. By stimulating cofilin (zeige CFL1 Proteine)/PP2A (zeige PPP2R4 Proteine)-mediated dephosphorylation of the guanine nucleotide exchange factor (zeige RASGRF1 Proteine) GEF-H1 (zeige ARHGEF2 Proteine).

  7. regulation of c-Src trafficking requires both microtubules and actin polymerization, and GEF-H1 coordinates c-Src trafficking, acting as a molecular switch between these two mechanisms

  8. Results supported that miR-512-3p could inhibit tumor cell adhesion, migration, and invasion by regulating the RAC1 activity via DOCK3 in NSCLC A549 and H1299 cell lines.

  9. Data indicate that forchlorfenuron (FCF) exhibits differential binding preference for septins SEPT2 (zeige SEPT2 Proteine) and SEPT3.

  10. TGF-beta (zeige TGFB1 Proteine) regulates LARG (zeige ARHGEF12 Proteine) and GEF-H1 (zeige ARHGEF2 Proteine) during epithelial-mesenchymal transition to affect stiffening response to force and cell invasion.

Mouse (Murine) Septin 3 (SEPT3) Interaktionspartner

  1. Sept3 is dispensable for normal neuronal development

  2. SEPT3 and SEPT5 (zeige SEPT5 Proteine) are dispensable for neuronal development as well as for synaptic vesicle fusion and recycling.

Septin 3 (SEPT3) Protein Überblick

Protein Überblick

This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Alternative names and synonyms associated with Septin 3 (SEPT3)

  • septin 3 (SEPT3)
  • septin 12 (sept12)
  • Rho/Rac guanine nucleotide exchange factor (GEF) 2 (ARHGEF2)
  • septin 3 (Sept3)
  • septin 3 (sept3)
  • solute carrier family 35, member F6 (Slc35f6)
  • 3110018K01Rik Protein
  • 4930471M23Rik Protein
  • 5730478O19Rik Protein
  • ANT2BP Protein
  • AV154067 Protein
  • B530002E20Rik Protein
  • bK250D10.3 Protein
  • GEF Protein
  • GEF-H1 Protein
  • GEFH1 Protein
  • LFP40 Protein
  • MGC69255 Protein
  • P40 Protein
  • Sep-03 Protein
  • Sep3 Protein
  • sept3 Protein
  • Tango9 Protein
  • zgc:110051 Protein

Bezeichner auf Proteinebene für Septin 3 Proteine (SEPT3)

septin 3 , septin 12 , putative septin 3 variant 1 , neuronal-specific septin-3-like , Rho/Rac guanine nucleotide exchange factor 2 , guanine nucleotide exchange factor H1 , microtubule-regulated Rho-GEF , proliferating cell nucleolar antigen p40 , rho guanine nucleotide exchange factor 2 , neuronal-specific septin 3 , neuronal-specific septin-3 , G-septin alpha , P40 , ANT2-binding protein , solute carrier family 35 member F6 , transmembrane protein C2orf18 homolog , transport and Golgi organization 9 homolog

458874 Pan troglodytes
594940 Xenopus (Silurana) tropicalis
100070757 Equus caballus
100189981 Taeniopygia guttata
100387629 Callithrix jacchus
100457064 Pongo abelii
100471219 Ailuropoda melanoleuca
9181 Homo sapiens
55964 Homo sapiens
481227 Canis lupus familiaris
100157034 Sus scrofa
618235 Bos taurus
24050 Mus musculus
56003 Rattus norvegicus
427899 Gallus gallus
554123 Danio rerio
74919 Mus musculus
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