anti-MUC1 (MUC1) Antikörper

Bezeichnung:
anti-Mucin 1, Cell Surface Associated Antikörper (MUC1)
Auf www.antikoerper-online.de finden Sie aktuell 1441 Mucin 1, Cell Surface Associated (MUC1) Antikörper von 37 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MUC1 Kits (104) und MUC1 Proteine (53) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1628 MUC1 Produkte verfügbar.
Synonyme:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, Muc-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM

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Am meisten referenzierte anti-MUC1 Antikörper

  1. Human Polyclonal MUC1 Primary Antibody für EIA, WB - ABIN951233 : Behrens, Grandgenett, Bailey, Singh, Yi, Yu, Hollingsworth: The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. in Oncogene 2010 (PubMed)
    Zeige alle 3 Referenzen für 951233

  2. Human Polyclonal MUC1 Primary Antibody für IF (p), IHC (p) - ABIN687367 : Taki, Ohmuraya, Tanji, Komatsu, Hashimoto, Semba, Araki, Kawaguchi, Baba, Furukawa: GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm. in Oncogene 2016 (PubMed)

  3. Human Polyclonal MUC1 Primary Antibody für IF (p), IHC (p) - ABIN673824 : Zong, Wu, Wang, Ju, Yan: Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening. in Analytical chemistry 2012 (PubMed)

  4. Human Polyclonal MUC1 Primary Antibody für IF, IHC - ABIN1533625 : Yu, Yang, Shew, Hong, Yang, Lee, Lee, Luh, Wu: Mucin mRNA expression in lung adenocarcinoma cell lines and tissues. in Oncology 1996 (PubMed)

  5. Human Monoclonal MUC1 Primary Antibody für IHC (p) - ABIN371859 : Margarit, Taylor, Roberts, Hopkins, Davies, Brenton, Conlan, Bunkheila, Joels, White, Gonzalez: MUC1 as a discriminator between endometrium from fertile and infertile patients with PCOS and endometriosis. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)

  6. Cow (Bovine) Polyclonal MUC1 Primary Antibody für IHC, WB - ABIN2776818 : Creaney, Segal, Sterrett, Platten, Baker, Murch, Nowak, Robinson, Millward: Overexpression and altered glycosylation of MUC1 in malignant mesothelioma. in British journal of cancer 2008 (PubMed)

Weitere Antikörper gegen MUC1 Interaktionspartner

Human Mucin 1, Cell Surface Associated (MUC1) Interaktionspartner

  1. Studied and analyzed MUC1 in specimens from patients with cholangiocarcinoma and pancreatic ductal adenocarcinoma. Using lectin microarray analysis, analyzed and found different glycoforms of MUC1 could distinguish between different cancers and degree of malignancy.

  2. These findings uncover a previously unrecognized role for MUC1-C in driving BMI1 (zeige BMI1 Antikörper) expression and in directly interacting with this stem cell factor (zeige KITLG Antikörper), linking MUC1-C with function of the PRC1 (zeige PRC1 Antikörper) in epigenetic gene silencing.

  3. our data suggest a novel molecular mechanism by which tMUC1 may modulate NRP1 (zeige NELL1 Antikörper)-dependent VEGFR (zeige KDR Antikörper) signaling in PDA cells.

  4. Results suggest that MUC1 serves as a metabolic regulator in triple-negative breast cancer, facilitating the metabolic reprogramming of glutamine (zeige GFPT1 Antikörper) utilization that influences triple-negative breast cancer tumor growth.

  5. MUC1-C is of functional importance to induction of DNMT1 (zeige DNMT1 Antikörper) and DNMT3b (zeige DNMT3B Antikörper) and, in turn, changes in DNA methylation (zeige HELLS Antikörper) patterns in cancer cells.

  6. The MUC1 oncoprotein was identified as the critical driver of (extracellular vesicle) EV-mediated myeloid-derived suppressor cells expansion in AML (zeige RUNX1 Antikörper). microRNA miR34a acts as the regulatory mechanism by which MUC1 drives c-myc (zeige MYC Antikörper) expression in AML (zeige RUNX1 Antikörper) cells and EVs.

  7. immunoexpression of different epitopes (external and cytoplasmic) of MUC1 expression are altered in tubes with ectopic pregnancy compared with normal tubes, suggesting an association to explain its etiology

  8. Data show that triple-negative breast cancer (TNBC) patients with pre-therapeutic serum high levels of both carcinoembryonic antigen (CEA (zeige CEACAM5 Antikörper)) and cancer antigen 15-3 (CA15-3) had shorter overall survival (OS) and disease-free survival (DFS (zeige FST Antikörper)) rates than those in the low-level groups.

  9. MUC1 expression correlates with tumor metastatic recurrence in postoperative esophageal squamous cell cancer patients

  10. Differences in the apparent expression levels of CEA (zeige CEACAM5 Antikörper), CA153 and CA125 (zeige MUC16 Antikörper) in patients with nipple discharge and healthy persons were validated.

Pig (Porcine) Mucin 1, Cell Surface Associated (MUC1) Interaktionspartner

  1. The results indicate that Muc1 gene is significantly associated with litter size in pigs.

  2. The epiblast expressed epithelial markers, MUC1 and E-CADHERIN (zeige CDH1 Antikörper), and the pluripotency markers, DNMT3B (zeige DNMT3B Antikörper) and CRIPTO (zeige TDGF1 Antikörper).

Cow (Bovine) Mucin 1, Cell Surface Associated (MUC1) Interaktionspartner

  1. Endometrial expressions of MUC1 and cytokine genes differed among normal, fertile versus diseased, and subfertile dairy cows.

  2. Bovine Muc1 prevents binding of bacteria to human intestinal cells and may have a role in preventing the binding of common enteropathogenic bacteria to human intestinal epithelial surfaces.

  3. concluded that bovine Muc1 protein is probably an inducible innate immune effector and an important component of the first line of defense against bacterial invasion of epithelial surfaces

Mouse (Murine) Mucin 1, Cell Surface Associated (MUC1) Interaktionspartner

  1. our data suggest a novel molecular mechanism by which tMUC1 may modulate NRP1 (zeige NRP1 Antikörper)-dependent VEGFR (zeige KDR Antikörper) signaling in PDA cells.

  2. Low expression of MUC1 is associated with lung carcinogenesis.

  3. Using an extensive collection of novel murine cell lines we have identified distinct roles for Kras and Pten (zeige PTEN Antikörper) on MUC1 and EMT (zeige ITK Antikörper) in vivo and in vitro. The data has implications for future design of combination therapies targeting Kras mutations, Pten (zeige PTEN Antikörper) deletions and MUC1 vaccines.

  4. Gp91phox (zeige CYBB Antikörper) NADPH oxidase (zeige NOX1 Antikörper) modulates litter size by up-regulating mucin1 expression in the uterus of mice.

  5. In summary, we have demonstrated that MUC1 on immune cells is a novel regulator of the NLRP3 (zeige NLRP3 Antikörper) inflammasome, and propose this is mediated by an interaction with signalling components at the cytoplasmic domains of TLRs that involves inhibition of IRAK4 (zeige IRAK4 Antikörper) activation.

  6. MUC1 regulates IL-1beta (zeige IL1B Antikörper) secretion induced by the NLRP3 (zeige NLRP3 Antikörper)-activating bacteria Haemophilus influenzae but not bacteria that activate other inflammasomes.

  7. Muc1 protection during acute kidney injury proceeds by enhancing both the HIF-1 (zeige HIF1A Antikörper) and beta-catenin (zeige CTNNB1 Antikörper) protective pathways.

  8. MAMs MUC1 and MUC16 (zeige MUC16 Antikörper) contribute to the maintenance of immune homeostasis at the ocular surface by limiting TLR-mediated innate immune responses.

  9. the present study provides evidence that Muc1 is a direct target of let-7a and let-7b in mouse uteri during embryo implantation.

  10. Anatomical site-specific Cre-loxP recombination throughout the genital tract of MUC1KrasPten mice leads to MUC1 positive genital tract tumors, and the development of these tumors is influenced by the anatomical environment

MUC1 Antigen-Profil

Beschreibung des Gens

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MUC1

  • mucin 1, cell surface associated (MUC1) Antikörper
  • mucin 1, cell surface associated (Muc1) Antikörper
  • mucin 1, transmembrane (Muc1) Antikörper
  • CA 15-3 Antikörper
  • CD227 Antikörper
  • EMA Antikörper
  • H23AG Antikörper
  • KL-6 Antikörper
  • MAM6 Antikörper
  • MCKD1 Antikörper
  • Muc-1 Antikörper
  • MUC-1/SEC Antikörper
  • MUC-1/X Antikörper
  • MUC1/ZD Antikörper
  • PEM Antikörper
  • PEMT Antikörper
  • PUM Antikörper

Bezeichner auf Proteinebene für MUC1

DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin , endometrial mucin-1 , epithelial mucin , MUC-1 , Mucin1

GENE ID SPEZIES
4582 Homo sapiens
448784 Canis lupus familiaris
397382 Sus scrofa
281333 Bos taurus
100009240 Oryctolagus cuniculus
24571 Rattus norvegicus
100733534 Cavia porcellus
17829 Mus musculus
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