TUBG1 Proteine (TUBG1)

Bezeichnung:
Tubulin, gamma 1 Proteine (TUBG1)
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Synonyme:
1500010O08Rik, AI451582, AI503389, gamma-tubulin, GCP-1, TUBC, Tubg, Tubg2, TUBG3, TUBGCP1, tubgl, xgam, zgc:55894
alle Proteine anzeigen Gen GeneID UniProt
TUBG1 7283 P23258
TUBG1 103733 P83887
TUBG1 252921 P83888

Weitere Synonyme anzeigen

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Am meisten referenzierte TUBG1 Proteine

  1. Human TUBG1 Protein expressed in Escherichia coli (E. coli) - ABIN667610 : Wise, Krahe, Oakley: The gamma-tubulin gene family in humans. in Genomics 2000 (PubMed)
    Zeige alle 2 Referenzen für 667610

Weitere Proteine zu TUBG1 Interaktionspartnern

Arabidopsis thaliana Tubulin, gamma 1 (TUBG1) Interaktionspartner

  1. MPK6 (zeige MAPK6 Proteine) phosphorylates EB1c, but not EB1a, and has a role in maintaining regular planes of cell division under stress conditions.

Cow (Bovine) Tubulin, gamma 1 (TUBG1) Interaktionspartner

  1. Authors report that the only viral nonstructural protein able to reproduce the loss of gamma-tubulin from the microtubule organizing center and the loss of integrity of the microtubule system is Foot-and-mouth disease virus 3C(pro).

Human Tubulin, gamma 1 (TUBG1) Interaktionspartner

  1. All GCPs are incorporated into the helix via lateral interactions between their N-terminal domains, whereas the C-terminal domains mediate longitudinal interactions with gamma-tubulin.

  2. While binding to gamma-tubulin may help target APC (zeige APC Proteine) to the site of microtubule nucleation complexes, additional C-terminal sequences of APC (zeige APC Proteine) are required to stimulate and stabilize microtubule growth.

  3. a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers

  4. Results show that CUL4A (zeige CUL4A Proteine)- and CUL4B (zeige CUL4B Proteine)-mediated polyubiquitination of gamma-tubulin for its degradation.

  5. In this study, the molecular basis of interaction between two lateral gamma-tubulin units within the gamma-tubulin ring complex were elucidated by making extensive use of molecular mechanics and molecular dynamics techniques.

  6. Gamma tubulin expression was associated with patients' age, astrocytoma grade, respectability, patient survival and performance. These factors may be important prognostic indicators for patients with astrocytomas.

  7. Recombinant gamma-tubulin can be phosphorylated by Cdk1 (zeige CDK1 Proteine)-cyclin B or Brsk1 (zeige BRSK1 Proteine) and dephosphorylated by Ppp4c (zeige PPP4C Proteine)-R2-R3A in vitro.

  8. Nek9 (zeige NEK9 Proteine) phosphorylates NEDD1 (zeige NEDD1 Proteine) on Ser377 driving its recruitment and thereby that of gamma-tubulin to the centrosome in mitotic cells.

  9. Our results reveal for the first time an increased expression of TUBG1 and TUBG2 (zeige TUBG2 Proteine) in lung cancer

  10. overexpression of Cdk1 (zeige CDK1 Proteine) or BRCA1 greatly expands the gamma-tubulin coating of microtubules, suggesting that the microtubule-bound gamma-tubulin is involved in DNA damage response.

Mouse (Murine) Tubulin, gamma 1 (TUBG1) Interaktionspartner

  1. Fodrin is a regulatory transporter of gamma-tubulin to the centrosomes for normal progression of mitosis.

  2. Data suggest that localization of Tubg1 (and Plk1 [polo-like kinase 1]) to spindle poles during oocyte meiotic maturation/oogenesis (metaphase I/II) requires participation of Uchl5ip/Haus7 (HAUS augmin-like complex subunit 7 (zeige HAUS7 Proteine)).

  3. a direct interaction with NEDD1 (zeige NEDD1 Proteine) regulates gamma-tubulin recruitment to the centrosome

  4. Gamma-tubulin is a key regulator of asymmetric cytokinesis in mouse oocytes.

  5. pPKCdelta(Thr505) interacts with MTOC-associated proteins pericentrin and gamma-tubulin, and plays a role in meiotic spindle organization in oocytes

  6. Results suggest that Fyn (zeige FYN Proteine) and PI3K might take part in the modulation of membrane-associated gamma-tubulin activities.

  7. SADB (zeige BRSK1 Proteine) kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin.

Xenopus laevis Tubulin, gamma 1 (TUBG1) Interaktionspartner

  1. Data show that depletion of either gamma-tubulin or XMAP215 was partially rescued by adding back XMAP215, but not by adding any of the other factors.

TUBG1 Protein Überblick

Protein Überblick

This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.

Alternative names and synonyms associated with TUBG1

  • gamma-tubulin1 (tubg1)
  • tubulin gamma-1 chain (TUBG1)
  • tubulin gamma-1 chain-like (TUBG1)
  • tubulin, gamma 1 (TUBG1)
  • tubulin, gamma 1 (Tubg1)
  • tubulin, gamma 1 (tubg1)
  • 1500010O08Rik Protein
  • AI451582 Protein
  • AI503389 Protein
  • gamma-tubulin Protein
  • GCP-1 Protein
  • TUBC Protein
  • Tubg Protein
  • Tubg2 Protein
  • TUBG3 Protein
  • TUBGCP1 Protein
  • tubgl Protein
  • xgam Protein
  • zgc:55894 Protein

Bezeichner auf Proteinebene für Tubulin, gamma 1 Proteine (TUBG1)

Tubulin gamma-3 chain , Zmtubg1 , gamma-1-tubulin , gamma-3-tubulin , tubg*-X78891 , tubulin gamma-1 chain , gamma-tubulin complex component 1 , tubulin, gamma polypeptide , GCP-1 , gamma tubulin , gamma-tubulin

GENE ID SPEZIES
542436 Zea mays
825338 Arabidopsis thaliana
786128 Bos taurus
420025 Gallus gallus
7283 Homo sapiens
103733 Mus musculus
252921 Rattus norvegicus
541101 Bos taurus
393882 Danio rerio
399272 Xenopus laevis
403695 Canis lupus familiaris
101686824 Mustela putorius furo
101097283 Felis catus
100861342 Capra hircus
101103906 Ovis aries
100719864 Cavia porcellus
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