anti-HSD11B1 (HSD11B1) Antikörper

Bezeichnung:
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 Antikörper (HSD11B1)
Auf www.antikoerper-online.de finden Sie aktuell 114 Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HSD11B1 Kits (35) und HSD11B1 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 175 HSD11B1 Produkte verfügbar.
Synonyme:
11-beta-HSD1, 11-DH, CORTRD2, HDL, hsd11, hsd11b, HSD11L, LRRGT00065, SDR26C1

Meistgesuchte Reaktivitäten zu anti-HSD11B1 (HSD11B1) Antikörper

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anti-Human HSD11B1 Antikörper:

anti-Mouse (Murine) HSD11B1 Antikörper:

anti-Rat (Rattus) HSD11B1 Antikörper:

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Am meisten referenzierte anti-HSD11B1 Antikörper

  1. Human Polyclonal HSD11B1 Primary Antibody für ELISA, WB - ABIN185329 : Paterson, Morton, Fievet, Kenyon, Holmes, Staels, Seckl, Mullins: Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Zeige alle 3 Referenzen für 185329

  2. Cow (Bovine) Polyclonal HSD11B1 Primary Antibody für IHC, WB - ABIN2773867 : Paulsen, Nielsen, Richelsen, Bruun, Flyvbjerg, Pedersen: Upregulation of adipose 11-beta-hydroxysteroid dehydrogenase type 1 expression in ovariectomized rats is due to obesity rather than lack of estrogen. in Obesity (Silver Spring, Md.) 2008 (PubMed)
    Zeige alle 3 Referenzen für 2773867

  3. Mouse (Murine) Polyclonal HSD11B1 Primary Antibody für ELISA, WB - ABIN4276641 : Sinclair, Walker, Burdon, van Beek, Kema, Hughes, Murray, Nightingale, Stewart, Rauz, Tomlinson: Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation? in The Journal of clinical endocrinology and metabolism 2010 (PubMed)

  4. Human Polyclonal HSD11B1 Primary Antibody für IF (p), IHC (p) - ABIN750913 : Nakata, Umeda, Masuzaki, Sawai: The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats. in BMC oral health 2016 (PubMed)

Weitere Antikörper gegen HSD11B1 Interaktionspartner

Human Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Interaktionspartner

  1. The reduction of DHT obese homozygotic twins could be linked to its increased degradation by AKR1C2 (zeige AKR1C2 Antikörper) and HSD11B1, and increased estrogen levels could be linked to increased adiposity-related expression of aromatase (zeige CYP19A1 Antikörper) in adipose tissue.

  2. this study shows that the phenotypic switch of adipose tissue macrophages from M2 to mixed M1/M2 phenotype occurred through differentiation of adipocytes in obese individuals, and upregulation of intracellular 11beta-HSD1 might play a role in the process

  3. 11beta-HSD-2 (zeige HSD11B2 Antikörper) plays an important role in the development of bone or osteoblast cell apoptosis, and the decreased expression of 11beta-HSD-2 (zeige HSD11B2 Antikörper) may aggravate steroid induced bone/osteoblast cell apoptosis.

  4. 11beta-HSD1 may be an important enzyme in the pathogenesis of fatty liver and visceral obesity.

  5. In HSD11B1 gene of rs3753519-stratified analysis, carriers of the minor allele presented significantly increased BMI, fasting plasma glucose and HOMA-IR. The study provides support for plausible implication of the HSD11B1 polymorphisms in susceptibility to develop undesirable effects of glucocorticoid replacement in Addison's disease.

  6. Increased 11beta-HSD1 expression and its reductase activity in granulosa cells are the major causes of increased cortisol concentration in the follicular fluid of PCOS with insulin (zeige INS Antikörper) resistance.

  7. Reciprocal regulation of the glucocorticoid metabolizing enzymes, 11beta-hydroxysteroid dehydrogenase types 1 and 2, is associated with steroid-responsiveness and disease remission in childhood nephrotic syndrome.

  8. increased cortisol and 11beta-HSD1 abundance and decreased LOX (zeige LOX Antikörper) abundance were observed in human amnion tissue after the labor-initiated spontaneous rupture of membranes

  9. These findings indicated that 11beta-HSD1 inhibition can give a potential benefit in reducing obesity and lowering insulin (zeige INS Antikörper) resistance by modulating the insulin (zeige INS Antikörper)-signaling pathway and adipocytokine production.

  10. Review of the role of HSD11B1 in pregnancy complications, fetal diseases, and later life morbidity.

Pig (Porcine) Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Interaktionspartner

  1. Results describe the cloning, sequence and expression of 11beta-hydroxysteroid dehydrogenase type 1 from pig testis.

  2. concluded that the 11beta-hydroxysteroid dehydrogenase (11beta-HSD1 and 2) system is involved in the regulation of cortisol activity in the testis and thus in the regulation of spermatogenesis

  3. Effects of age, weaning and/or social isolation on the expression of genes regulating HSD11B1.

Cow (Bovine) Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Interaktionspartner

  1. HSD11B1 was localized in mature adipocytes of early lactating cows, indicating that circulating glucocorticoids promote effects other than differentiation.

  2. investigation of gene expression for 11HSD1, 11HSD2 (zeige HSD11B2 Antikörper), and glucocorticoid receptor (zeige NR3C1 Antikörper) in granulosa cells and theca interna layers during follicular maturation and atresia: expression of 11HSD1 is developmentally regulated in maturing follicles

  3. PGF2alpha but not PGE2 increases HSD11B1 bioactivity and protein expression by stimulating a posttranscriptional mechanism in stromal cells.

Mouse (Murine) Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) Interaktionspartner

  1. These data identify suppression of CXCL2 (zeige CXCL2 Antikörper) and CXCL5 (zeige CXCL5 Antikörper) chemoattractant expression by 11beta-HSD1 as a novel mechanism with potential for regulation of neutrophil recruitment to the injured myocardium, and cardiac fibroblasts as a key site for intracellular glucocorticoid regeneration during acute inflammation following myocardial injury.

  2. Brown adipose tissue (BAT (zeige BAAT Antikörper)) from aged 11beta-HSD1 KO mice showed elevated UCP1 (zeige UCP1 Antikörper) protein and mitochondrial content, and a favorable profile of BAT (zeige BAAT Antikörper) function.

  3. We envisage these data and models finding utility when investigating the muscle-specific functions of the 11beta-HSD1/G6PT/H6PDH triad.

  4. 11beta-HSD1-deficient mice are not protected from metabolic disease or hepatosteatosis in the face of a nonalcoholic fatty liver disease-inducing diet.

  5. 11beta-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.

  6. these data suggest that corticosterone activation by 11beta-HSD1 in keratinocytes suppresses hapten-induced irritant dermatitis through suppression of expression of cytokines

  7. Nr3c2 (zeige NR3C2 Antikörper) has a role in mouse skin development in a process that involves HSD11B1/HSD11B2 (zeige HSD11B2 Antikörper)

  8. Loss of 11beta-HSD1 is associated with hepatocellular carcinoma.

  9. These findings suggest that 11beta-HSD1 may contribute to the decline in Npas4 (zeige NPAS4 Antikörper) and Arc (zeige NOL3 Antikörper) mRNA levels associated with memory impairment during ageing

  10. Our results demonstrate an inhibitory effect of IGF-I (zeige IGF1 Antikörper) on 11beta-HSD1 expression and activity within the pancreatic islets, which may mediate part of the IGF-I (zeige IGF1 Antikörper) effects on cell proliferation, survival and insulin (zeige INS Antikörper) secretion

HSD11B1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with HSD11B1

  • hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1) Antikörper
  • Corticosteroid 11-beta-dehydrogenase isozyme 1-like (LOC100342395) Antikörper
  • hydroxysteroid (11-beta) dehydrogenase 1 (hsd11b1) Antikörper
  • hydroxysteroid (11-beta) dehydrogenase 1 (Hsd11b1) Antikörper
  • hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1) Antikörper
  • 11-beta-HSD1 Antikörper
  • 11-DH Antikörper
  • CORTRD2 Antikörper
  • HDL Antikörper
  • hsd11 Antikörper
  • hsd11b Antikörper
  • HSD11L Antikörper
  • LRRGT00065 Antikörper
  • SDR26C1 Antikörper

Bezeichner auf Proteinebene für HSD11B1

11-beta-hydroxysteroid dehydrogenase 1 , hydroxysteroid 11-beta dehydrogenase 1 , hydroxysteroid (11-beta) dehydrogenase 1 , corticosteroid 11-beta-dehydrogenase isozyme 1 , short chain dehydrogenase/reductase family 26C, member 1 , 11-DH , 11-beta-HSD1 , 11-beta-hydroxysteroid dehydrogenase type 1 , 11-beta hydroxysteroid dehydrogenase , 11 beta-hydroxysteroid dehydrogenase type 1 , 7-alpha-HCD , 7-alpha-hydroxycholesterol dehydrogenase , 11beta-HSD-1 , 11beta-HSD1A , 11beta-hydroxysteroid dehydrogenase type 1 , Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A) , cortocosteroid 11-beta dehydrogenase , hydroxysteroid dehydrogenase, 11 beta type 1

GENE ID SPEZIES
457698 Pan troglodytes
574322 Macaca mulatta
419861 Gallus gallus
100342395 Oryctolagus cuniculus
3290 Homo sapiens
443409 Ovis aries
379497 Xenopus laevis
449023 Canis lupus familiaris
397480 Sus scrofa
282589 Bos taurus
101835279 Mesocricetus auratus
15483 Mus musculus
25116 Rattus norvegicus
100135542 Cavia porcellus
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