anti-CYP27B1 (CYP27B1) Antikörper

anti-Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 Antikörper (CYP27B1)
Auf finden Sie aktuell 30 Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CYP27B1 Kits (16) und CYP27B1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 55 CYP27B1 Produkte verfügbar.
Cp2b, Cyp1, CYP1alpha, Cyp27b, Cyp40, P450c1, Pddr, Vdd1, Vddr, VddrI, Vdr

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anti-Human CYP27B1 Antikörper:

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Am meisten referenzierte anti-CYP27B1 Antikörper

  1. Human Polyclonal CYP27B1 Primary Antibody für FACS, IHC (p) - ABIN652999 : Simon, Munger, Xing Yang, Ascherio: Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis. in Multiple sclerosis (Houndmills, Basingstoke, England) 2010 (PubMed)
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Weitere Antikörper gegen CYP27B1 Interaktionspartner

Cow (Bovine) Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) Interaktionspartner

  1. Data show that in tissue and secreted cells from the infected mammary glands, 25-hydroxyvitamin D(3) 1alpha-hydroxylase (1alpha-OHase; CYP27B1) gene expression was significantly increased compared to expression in tissue and cells from the healthy mammary tissue.

Human Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) Interaktionspartner

  1. Women with Recurrent Miscarriage have a lower level of CYP27B1 expression in chorionic villi and decidua compared with normal pregnant women, suggesting that reduced CYP27B1 expression may be associated with Recurrent Miscarriage.

  2. Mutation in CYP27B1 is associated with Vitamin D-Dependent Rickets Type 1.

  3. Male placental cotyledons showed reduced basal CYP27B1 and cathelicidin gene expression compared to females.

  4. Expression of CYP27B1 was in spermatozoa from healthy controls compared with infertile men, however the percentage of spermatozoa expressing CYP27B1 was not significantly higher.

  5. A Case of Vitamin-D-Dependent Rickets Type 1A with Normal 1,25-Dihydroxyvitamin D Caused by Two Novel Mutations of the CYP27B1 Gene.

  6. The aim of the present study was to investigate the mRNA expression levels of the CYP24A1 (zeige CYP24A1 Antikörper) and CYP27B1 genes in malignant and normal breast tissues. The results demonstrated that the mRNA expression of CYP27B1 was downregulated in the tumor tissues, compared with the adjacent normal tissues (P<0.01), whereas the mRNA expression of CYP24A1 (zeige CYP24A1 Antikörper) was significantly upregulated in the tumor tissues (P<0.01).

  7. findings do not support a role of an independent effect of the investigated vitamin D-related gene variants, VDBP (zeige GC Antikörper) and CYP27B1, in the risk of Multiple Sclerosis

  8. In Sjogren's syndrome (SS) patients, EULAR Sjogren's syndrome disease activity index (ESSDAI) is negatively associated with serum levels of 25(OH)-D3 and positively associated with BAFF (zeige TNFSF13B Antikörper).

  9. This study reveals no association between CYP27B1 polymorphisms and blood levels of 1alpha,25-hydroxyvitamin D.

  10. this study indicates rs8176345 in CYP27B1 gene is significantly correlated with erlotinib-induced skin rash in patients with advanced non-small cell lung cancer

Mouse (Murine) Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) Interaktionspartner

  1. The data indicate that abnormal osteoclastogenesis due to the absence of CYP27B1 expression, consistent with the notion that endogenous metabolism of 25-hydroxyvitamin D optimizes osteoclastogenesis and ameliorates the resulting activity of mature osteoclasts.

  2. The absence of 25-hydroxyvitamin D3-1alpha-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light.

  3. Cyp27b1(-/-) mice exhibited hypocalcemia, growth defects, and skeletogenesis dysfunction, similar to Vdr(-/-) mice, but do not display alopecia

  4. Findings demonstrate that in-tumor CYP27B1 1-alpha-hydroxylase activity plays a crucial role in controlling early oncogene (zeige RAB1A Antikörper)-mediated mammary carcinogenesis events, at least in part by modulating tumoral cell NF-kappaB (zeige NFKB1 Antikörper) p65 (zeige NFkBP65 Antikörper) nuclear translocation.

  5. the effect of 25-hydroxyvitamin D-1-alpha-hydroxylase on the atherosclerosis disease both in apolipoprotein (apo) E (zeige APOE Antikörper)-/- mice and wild-type mice, was investigated.

  6. P450C1 alpha deficiency results in abnormal calcium handling and cardiac dysfunction in mice with defective vitamin D signaling.

  7. Throughout the male reproductive tract specific bands of CYP27B1 are determined.

  8. observed a 3- to 10-fold increase in CYP27B1 mRNA abundance in the lung, spleen, aorta and testis of FGF-23 (zeige FGF23 Antikörper) null/1alpha-Luc mice

  9. Data show that the absence of either of the two key hydroxylases, vitamin D 25-hydroxylase (CYP2R1 (zeige CYP2R1 Antikörper)) or vitamin D 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1)neither inhibits nor enhances the development of experimental autoimmune encephalomyelitis (EAE).

  10. These results confirm the expression of vitamin D receptor (zeige VDR Antikörper) and Cyp27b1 in vivo and suggest a potential role for vitamin D(3) in skeletal muscle regeneration following injury.

CYP27B1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.

Alternative names and synonyms associated with CYP27B1

  • cytochrome P450, family 27, subfamily B, polypeptide 1 (cyp27b1) Antikörper
  • cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1) Antikörper
  • cytochrome P450, family 27, subfamily b, polypeptide 1 (Cyp27b1) Antikörper
  • Cp2b Antikörper
  • Cyp1 Antikörper
  • CYP1alpha Antikörper
  • Cyp27b Antikörper
  • Cyp40 Antikörper
  • P450c1 Antikörper
  • Pddr Antikörper
  • Vdd1 Antikörper
  • Vddr Antikörper
  • VddrI Antikörper
  • Vdr Antikörper

Bezeichner auf Proteinebene für CYP27B1

cytochrome P450, family 27, subfamily B, polypeptide 1 , 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial , mitochondrial 25 hydroxyvitamin D3-1alpha-hydroxylase , 1alpha(OH)ase , 25 hydroxyvitamin D3-1-alpha hydroxylase , 25-OHD-1 alpha-hydroxylase , VD3 1A hydroxylase , calcidiol 1-monooxygenase , cytochrome P450 subfamily XXVIIB polypeptide 1 , cytochrome P450C1 alpha , cytochrome P450VD1-alpha , cytochrome p450 27B1 , 25-hydroxyvitamin D(3) 1-alpha-hydroxylase , P450C1 alpha , P450VD1-alpha , cytochrome P450 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase) , cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1 , cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase) , cytochrome P450, subfamily 27b, polypeptide 1 , 25(OH)D 1alpha-hydroxylase , 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD3 1A hydroxylase) (P450C1 alpha) (P450VD1-alpha) , 25-hydroxyvitamin D3 1alpha-hydroxylase , P450VD1alpha , cytochrome P450, 27b1

448754 Xenopus (Silurana) tropicalis
452027 Pan troglodytes
539630 Bos taurus
715747 Macaca mulatta
100034100 Equus caballus
1594 Homo sapiens
114700 Rattus norvegicus
13115 Mus musculus
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