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RPS6KA6 Proteine (RPS6KA6)

Bezeichnung:
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6 Proteine (RPS6KA6)
Auf www.antikoerper-online.de finden Sie aktuell 7 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6 (RPS6KA6) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RPS6KA6 Antikörper (40) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 53 RPS6KA6 Produkte verfügbar.
Synonyme:
2610524K04Rik, PP90RSK4, rps6ka6, RSK4, wu:fj94b02, zgc:66139
alle Proteine anzeigen Gen GeneID UniProt
RPS6KA6 67071 Q7TPS0
RPS6KA6 27330 Q9UK32

Weitere Synonyme anzeigen

RPS6KA6 Proteine (RPS6KA6) nach Spezies

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Am meisten referenzierte RPS6KA6 Proteine

  1. Human RPS6KA6 Protein expressed in Baculovirus infected Insect Cells - ABIN2002168 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)

Weitere Proteine zu RPS6KA6 Interaktionspartnern

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6 (RPS6KA6) Interaktionspartner

  1. Rsk4 inhibits the transcriptional activation of specific targets of receptor tyrosine kinase (zeige ERBB3 Proteine) signaling as well as the activation of ERK (zeige EPHB2 Proteine)

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6 (RPS6KA6) Interaktionspartner

  1. RSK4 is expressed at low levels in malignant ovarian tumors, which correlates with advanced stages of the disease.

  2. downregulation of RSK4 expression is indicated to be associated with tumor cell proliferation and invasion, and silencing of the RSK4 may be involved in the development and progression of breast cancer

  3. Low RSK4 expression is correlated with advanced clinical pathologic classifications and is a poor overall survival in colorectal cancer patients

  4. RSK4 mRNA is significantly decreased in most of breast cancer tissues compared with paired non-cancerous tissues, due to promoter hypermethylation; frequent epigenetic inactivation might have a role in precancerous lesions or early cancer

  5. evaluated expression of RSK4 in renal cell carcinoma (zeige MOK Proteine)(RCC (zeige XRCC1 Proteine))tissues, analysed relationship between RSK4 expression and clinicopathological features of RCC (zeige XRCC1 Proteine) patients and explored potential molecular mechanisms of RSK4 in RCC (zeige XRCC1 Proteine) cell lines; expression pattern and molecular mechanisms of RSK4 in RCCs indicate it could be a potential independent prognostic factor

  6. Overexpression of RSK3 (zeige RPS6KA2 Proteine) or RSK4 supports tumor cell proliferation upon PI3K (zeige PIK3CA Proteine) inhibition both in vitro and in vivo therby contributing to drug resistance.

  7. findings reveals a major role of PRKX (zeige PRKX Proteine), TTBK2 (zeige TTBK2 Proteine) and RSK4 in triggering Sunitinib resistance formation; data suggest transcriptional regulation of these kinases together with other proteins might play an important role in formation of Sunitinib resistance by affecting transcription factors

  8. Suggest that RSK4 may serve as a mediator of endothelial progenitor cell senescence in diabetes mellitus.

  9. The expression level of RSK-4 mRNA in breast cancer was significantly lower than those in normal breast tissues and breast benign lesions tissues. The down-regulation of RSK-4 expression in breast caner suggests that it is a breast cancer suppressor gene.

  10. Data indicate that RSK4 appears to be epigenetically silenced in endometrial cancer as evidenced by hypermethylation.

RPS6KA6 Protein Überblick

Protein Überblick

This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways.

Alternative names and synonyms associated with RPS6KA6

  • ribosomal protein S6 kinase polypeptide 6 (Rps6ka6)
  • ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6)
  • ribosomal protein S6 kinase, like (rps6kal)
  • 2610524K04Rik Protein
  • PP90RSK4 Protein
  • rps6ka6 Protein
  • RSK4 Protein
  • wu:fj94b02 Protein
  • zgc:66139 Protein

Bezeichner auf Proteinebene für RPS6KA6

S6K-alpha-6 , ribosomal protein S6 kinase alpha-6 , 90 kDa ribosomal protein S6 kinase 6 , RSK-4 , S6K-alpha 6 , p90-RSK 6 , p90RSK6 , ribosomal S6 kinase 4 , S6K-alpha 6-like , ribosomal protein S6 kinase polypeptide 6

GENE ID SPEZIES
67071 Mus musculus
27330 Homo sapiens
337670 Danio rerio
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