MAPK7 Proteine (MAPK7)

Mitogen-Activated Protein Kinase 7 Proteine (MAPK7)
Auf finden Sie aktuell 12 Mitogen-Activated Protein Kinase 7 (MAPK7) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPK7 Antikörper (201) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 221 MAPK7 Produkte verfügbar.
A330097D03Rik, ATMPK7, Bmk1, ERK-5, Erk3, ERK4, Erk5, Erk5-T, F8D23.5, F8D23_5, MAP kinase 7, p63Mapk, Prkm4, Prkm7
alle Proteine anzeigen Gen GeneID UniProt
MAPK7 225724 Q6P5G0
Ratte MAPK7 MAPK7 54268  
MAPK7 5598 Q13164

Weitere Synonyme anzeigen

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Weitere Proteine zu MAPK7 Interaktionspartnern

Mouse (Murine) Mitogen-Activated Protein Kinase 7 (MAPK7) Interaktionspartner

  1. These results suggest that YAP (zeige YAP1 Proteine) promotes muscle differentiation by activating the Abl (zeige ABL1 Proteine)/Src (zeige SRC Proteine)/MEKK3 (zeige MAP3K3 Proteine)/MEK5 (zeige MAP2K5 Proteine)/ERK5 kinase cascade.

  2. our results offer a preclinical proof of concept for ERK5 as a target to enhance T-cell infiltrates in prostate cancer

  3. This study indicated that MAN can protect osteoblast against oxidative damage by modulation of ERK5/Nrf2 (zeige NFE2L2 Proteine) signaling, which can be new agent for osteoporosis.

  4. These findings suggest that atherogenic conditions critically regulate platelet CD36 (zeige CD36 Proteine) signaling by increasing superoxide radical anion and hydrogen peroxide through a mechanism that promotes activation of MAPK (zeige MAPK1 Proteine) ERK5.

  5. Fluid shear stress acts on the Galphaq (zeige GNAQ Proteine)-ERK5 signaling pathway to upregulate Cyclin B1 (zeige CCNB1 Proteine) and CDK1 (zeige CDK1 Proteine) expression, thereby resulting in MC3T3-E1 cell proliferation.

  6. Finally, we demonstrated that miR (zeige MLXIP Proteine)-24 plays the modulational role by directly repressing MAPK7, a key number in the MAPK (zeige MAPK1 Proteine) signaling pathway. These data indicate that miR (zeige MLXIP Proteine)-24 is a novel positive regulator of adipocyte differentiation by targeting MAPK7, which provides new insights into the molecular mechanism of miRNA-mediated cellular differentiation.

  7. the activation of ERK5-AKT (zeige AKT1 Proteine)-FoxO3a (zeige FOXO3 Proteine) signaling pathways by fluid shear stress resulted in a decreased expression of FasL (zeige FASL Proteine) and Bim (zeige BCL2L11 Proteine) and an inhibition of caspase-3 (zeige CASP3 Proteine) activation, which exerts a protective effect that prevents osteoblasts from apoptosis.

  8. Data, including data from studies in knockout mice, suggest that Erk5/Mapk7 is required for tobacco smoke-triggered gastric epithelial-mesenchymal transition; can be suppressed by dietary factors (here, supplementation with epigallocatechin-3-gallate); suppression of Erk5/Mapk7 activation reverses tobacco smoke-triggered epithelial-mesenchymal transition in gastric mucosa.

  9. ERK5 activation is essential for osteoclast differentiation.

  10. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.

Human Mitogen-Activated Protein Kinase 7 (MAPK7) Interaktionspartner

  1. These findings suggest that atherogenic conditions critically regulate platelet CD36 (zeige CD36 Proteine) signaling by increasing superoxide radical anion and hydrogen peroxide through a mechanism that promotes activation of MAPK (zeige MAPK1 Proteine) ERK5.

  2. expression of miR (zeige MLXIP Proteine)-143 in osteosarcoma cells inhibited cell proliferation and migration/invasion. Bioinformatics and luciferase reporter assays confirmed that MAPK7 was targets gene of miR (zeige MLXIP Proteine)-143.

  3. miR (zeige MLXIP Proteine)-143 down-regulated its target ERK5, leading to the suppression of epithelial-mesenchymal transition induced by GSK-3beta/Snail (zeige SNAI1 Proteine) signaling of breast cancer.

  4. this study revealed the functional and mechanistic links between CDK5 (zeige CDK5 Proteine) and the oncogenic ERK5-AP-1 (zeige FOSB Proteine) signaling pathway in the pathogenesis of colorectal cancer.

  5. Present study revealed the positive role of ERK5/AP-1 (zeige FOSB Proteine) in benzidine-provoked urocystic epithelial-mesenchymal transition and the curcumin promising use in bladder cancer prevention and intervention via ERK5/AP-1 (zeige FOSB Proteine) pathway.

  6. miR (zeige MLXIP Proteine)-200b-3p suppresses glioma tumor growth, invasion, and reverses EMT (zeige ITK Proteine) through downregulated its target ERK5.

  7. Results indicate that MAPK7 may be modulating the growth, proliferation, migration and invasion of osteosarcoma cells.

  8. Thus ERK5 signaling is unlikely to play a role in tumor cell proliferation downstream of KRAS or BRAF (zeige BRAF Proteine) or in tumor cells with ERK5 amplification. These results have important implications for the role of ERK5 as an anti-cancer drug target

  9. data implied the up-regulated MAPK7 might contribute to ovarian cancer metastasis

  10. The results pf this study indicated that BMK1 modulation by miR (zeige MLXIP Proteine)-429 has an important function in glioma invasion both in vitro and in vivo.

Arabidopsis thaliana Mitogen-Activated Protein Kinase 7 (MAPK7) Interaktionspartner

  1. Data showed that expression of the MKK7 (zeige MAP2K7 Proteine) gene in wild-type plants is induced by pathogen infection. Reducing mRNA levels of MKK7 (zeige MAP2K7 Proteine) by antisense RNA expression not only compromises basal resistance, but also blocks the induction of SAR (zeige SRL Proteine).

MAPK7 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Alternative names and synonyms associated with MAPK7

  • mitogen-activated protein kinase 4 (Mapk4)
  • mitogen-activated protein kinase 7 (MAPK7)
  • mitogen-activated protein kinase 7 (Mapk7)
  • mitogen-activated protein kinase 7 (MPK7)
  • A330097D03Rik Protein
  • ATMPK7 Protein
  • Bmk1 Protein
  • ERK-5 Protein
  • Erk3 Protein
  • ERK4 Protein
  • Erk5 Protein
  • Erk5-T Protein
  • F8D23.5 Protein
  • F8D23_5 Protein
  • MAP kinase 7 Protein
  • p63Mapk Protein
  • Prkm4 Protein
  • Prkm7 Protein

Bezeichner auf Proteinebene für MAPK7

ERK-4 , Erk3-related , MAP kinase 4 , MAPK 4 , extracellular signal-regulated kinase 4 , mitogen activated protein kinase 4 , MAP kinase isoform p63 , MNK2 , p63-MAPK , BMK-1 , BMK1 kinase , ERK-5 , MAP kinase 7 , MAPK 7 , big MAP kinase 1 , extracellular signal-regulated kinase 5 , extracellular-signal-regulated kinase 5 , extracellular signal regulated kinase 5 , mitogen activated protein kinase 7 , mitogen-activated kinase 7 , Big MAP kinase 1 , Extracellular signal-regulated kinase 5

225724 Mus musculus
54268 Rattus norvegicus
5598 Homo sapiens
23939 Mus musculus
114509 Rattus norvegicus
537703 Bos taurus
816330 Arabidopsis thaliana
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