anti-BAD (BAD) Antikörper

anti-BCL2-Associated Agonist of Cell Death Antikörper (BAD)
Auf finden Sie aktuell 993 BCL2-Associated Agonist of Cell Death (BAD) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BAD Kits (52) und BAD Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1132 BAD Produkte verfügbar.
AI325008, BAD, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04

Meistgesuchte Reaktivitäten zu anti-BAD (BAD) Antikörper

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anti-Human BAD Antikörper:

anti-Mouse (Murine) BAD Antikörper:

anti-Rat (Rattus) BAD Antikörper:

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Am meisten referenzierte anti-BAD Antikörper

  1. Human Polyclonal BAD Primary Antibody für EIA, IHC (p) - ABIN358087 : Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 5 Referenzen für 358087

  2. Human Polyclonal BAD Primary Antibody für FACS, IHC (p) - ABIN388118 : Won, Kim, La, Kim, Meadows, Joe: Cleavage of 14-3-3 protein by caspase-3 facilitates bad interaction with Bcl-x(L) during apoptosis. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 3 Referenzen für 388118

  3. Human Polyclonal BAD Primary Antibody für IHC (p), WB - ABIN389520 : Antignani, Youle: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. in Biochemistry 2005 (PubMed)
    Zeige alle 2 Referenzen für 389520

  4. Human Polyclonal BAD Primary Antibody für IF, IHC - ABIN1531524 : Wang, Rapp, Reed: Bcl-2 targets the protein kinase Raf-1 to mitochondria. in Cell 1997 (PubMed)

  5. Cow (Bovine) Polyclonal BAD Primary Antibody für WB - ABIN2779324 : Xia, Zhang, Du, Pan, Zhao, Sun, Hong, Liu, Fan: miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. in International journal of cancer. Journal international du cancer 2008 (PubMed)

Weitere Antikörper gegen BAD Interaktionspartner

Zebrafish BCL2-Associated Agonist of Cell Death (BAD) Interaktionspartner

  1. Bad functions as an essential sensitizer and Puma (zeige BBC3 Antikörper) as an essential activator of IR-induced mitochondrial apoptosis specifically in embryonic neural tissue.

  2. Stage-specific expression of TNFalpha (zeige TNF Antikörper) regulates bad/bid (zeige BID Antikörper)-mediated apoptosis and RIP1 (zeige RALBP1 Antikörper)/ROS (zeige ROS1 Antikörper)-mediated secondary necrosis in Birnavirus-infected fish cells.

  3. Results indicate that zebrafish BH3-only (zeige BBC3 Antikörper) proapoptotic protein (BAD) could induce apoptosis in vitro and in vivo and may have biological implications in apoptosis during zebrafish development.

Human BCL2-Associated Agonist of Cell Death (BAD) Interaktionspartner

  1. The long unstructured region of Bcl-xl (zeige BCL2L1 Antikörper) modulates its structural dynamics.

  2. Short-term treatment of nascent melanoma tumors with PAK inhibitors that block RhoJ (zeige RHOJ Antikörper) signaling halts the growth of BRAF (zeige BRAF Antikörper) mutant melanoma tumors in vivo and induces apoptosis in melanoma cells in vitro via a BAD-dependent mechanism. As up to 50% of BRAF (zeige BRAF Antikörper) mutant human melanomas express high levels of RhoJ (zeige RHOJ Antikörper), these studies nominate the RhoJ (zeige RHOJ Antikörper)-BAD signaling network as a therapeutic vulnerability for fledgling BRAF (zeige BRAF Antikörper) mutant human tumor

  3. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (zeige BCL2L1 Antikörper) on the priming of Bax (zeige BAX Antikörper). As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (zeige BCL2L1 Antikörper), and of Bcl-2 (zeige BCL2 Antikörper), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  4. the accumulation of reactive oxygen species (ROS (zeige ROS1 Antikörper)) in cells expressing JAK2V617F compromises the NHE-1 (zeige SLC9A1 Antikörper)/Bcl-xL (zeige BCL2L1 Antikörper) deamidation pathway by repressing NHE-1 (zeige SLC9A1 Antikörper) upregulation in response to DNA damage. hematopoietic stem cells (HSCs), FOXO3A (zeige FOXO3 Antikörper) is largely localized within the nuclei despite the presence of JAK2V617F mutation, suggesting that JAK2 (zeige JAK2 Antikörper)-FOXO (zeige FOXO3 Antikörper) signaling has a different effect on progenitors compared with stem cells.

  5. These results identify beta3 integrin (zeige ITGB3 Antikörper) signaling via repression of BAD as an important survival pathway used by breast cancer cells to evade chemotherapy induced stress.

  6. miR (zeige MLXIP Antikörper)-377 was markedly downregulated in HCC (zeige FAM126A Antikörper) cell lines and primary human HCC (zeige FAM126A Antikörper) tissues. The decreased expression of miR (zeige MLXIP Antikörper)-377 contributes to the upregulation of Bcl-xL (zeige BCL2L1 Antikörper) expression by targeting its 3'-untranslated region (3'-UTR (zeige UTS2R Antikörper)).

  7. By the pharmacologic targeting of BCL2 (zeige BCL2 Antikörper), MCL1 (zeige MCL1 Antikörper), and BCL-XL (zeige BCL2L1 Antikörper), we demonstrated that diffuse large B-cell lymphoma can be divided into BCL2 (zeige BCL2 Antikörper)-dependent and MCL1 (zeige MCL1 Antikörper)-dependent subgroups with a less pronounced role left for BCL-XL (zeige BCL2L1 Antikörper).

  8. increased platelet apoptosis and activation as well as reduced expression of Bcl-xL (zeige BCL2L1 Antikörper), increased expression of Bax (zeige BAX Antikörper) and caspase-3 (zeige CASP3 Antikörper) activity were found in platelets after treated with ITP (zeige ITPA Antikörper) plasma in comparison with control plasma.

  9. These findings demonstrated that Akt (zeige AKT1 Antikörper) is related to NF-kappaB (zeige NFKB1 Antikörper) and Bad signaling pathway possibly playing a direct role in the progression of liver cancer. Thus, Akt (zeige AKT1 Antikörper) might be an important and potential treatment choice for the clinical diagnosis and treatment in the future.

  10. Bh3 domain induced conformational changes in Bcl-Xl (zeige BCL2L1 Antikörper) revealed by crystal structure and comparative analysis.

Mouse (Murine) BCL2-Associated Agonist of Cell Death (BAD) Interaktionspartner

  1. Bad is dispensable for TNF (zeige TNF Antikörper)-mediated cell death.

  2. Results indicate the downstream targets of insulin (zeige INS Antikörper), cyclin D1 (zeige CCND1 Antikörper), BAD, alpha-MHC (zeige MYH6 Antikörper), and GATA-4 (zeige GATA4 Antikörper), elucidate a molecular mechanism of insulin (zeige INS Antikörper) in promoting cell proliferation and differentiation.

  3. our study suggests that Bad and Bmf (zeige BMF Antikörper) co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.

  4. Results reveal that IKK (zeige CHUK Antikörper) inhibits TNFalpha (zeige TNF Antikörper)-induced apoptosis through two distinct but cooperative mechanisms: activation of the survival factor NF-kappaB (zeige NFKB1 Antikörper) and inactivation of the proapoptotic BH3-only (zeige BBC3 Antikörper) BAD protein.

  5. RNAi-mediated silencing of STAT1 (zeige STAT1 Antikörper) in soft tissue sarcoma (STS (zeige STS Antikörper)) cells was sufficient to increase expression of the apoptotic mediators Fas (zeige FAS Antikörper) and Bad and to elevate the sensitivity of STS (zeige STS Antikörper) cells to Fas (zeige FAS Antikörper)-mediated apoptosis

  6. Tonicity-induced COX-2 (zeige COX2 Antikörper) expression and PGE2 synthesis in the renal medulla entails phosphorylation and inactivation of the pro-apoptotic protein Bad, thereby counteracting apoptosis in renal medullary epithelial cells.

  7. Caspase-3 (zeige CASP3 Antikörper) is activated by the BAD-BAX (zeige BAX Antikörper) cascade resulting in long term depression induction in the hippocampus.

  8. JNK1 (zeige MAPK8 Antikörper) is required for erythropoietin (zeige EPO Antikörper)-mediated cell survival through phosphorylation and inactivation of the pro-apoptotic, Bcl-2 (zeige BCL2 Antikörper) homology domain 3 (BH3)-only (zeige BBC3 Antikörper) Bcl-associated death protein (Bad).

  9. Bad protein cooperate with bim (zeige BCL2L11 Antikörper) protein in certain apoptotic responses and in the suppression of g-irradiation-induced thymic lymphoma.(Bad protein)

  10. Data show that loss of Bmf (zeige BMF Antikörper) reduced the pressure to inactivate p53 (zeige TP53 Antikörper), whereas Bad deficiency did not, identifying Bmf (zeige BMF Antikörper) as a novel component of the p53 (zeige TP53 Antikörper)-independent tumor suppressor pathway triggered by c-Myc (zeige MYC Antikörper).

Cow (Bovine) BCL2-Associated Agonist of Cell Death (BAD) Interaktionspartner

BAD Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Alternative names and synonyms associated with BAD

  • BCL2-antagonist of cell death b (badb) Antikörper
  • BCL2-associated agonist of cell death (BAD) Antikörper
  • BCL2-associated agonist of cell death (Bad) Antikörper
  • AI325008 Antikörper
  • BAD Antikörper
  • Bbc2 Antikörper
  • BCL2L8 Antikörper
  • fa01b12 Antikörper
  • wu:fa01b12 Antikörper
  • wu:fa96d04 Antikörper

Bezeichner auf Proteinebene für BAD

proapoptotic BH3-only protein , BCL2-antagonist of cell death , BCL2-associated agonist of cell death , BCL-X/BCL-2 binding protein , BCL2-antagonist of cell death protein , BCL2-binding component 6 , BCL2-binding protein , bcl-2-binding component 6 , bcl-2-like protein 8 , bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , bcl2-L-8 , Bcl-associated death promoter , bcl-xL/Bcl-2-associated death promoter , Bcl2-antagonist of cell death , bcl-2 associated death agonist , bcl2-associated death promoter

58100 Danio rerio
768269 Felis catus
780444 Ovis aries
572 Homo sapiens
12015 Mus musculus
64639 Rattus norvegicus
483763 Canis lupus familiaris
615013 Bos taurus
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