anti-Prothrombin (F2) Antikörper

Bezeichnung:
anti-Coagulation Factor II (thrombin) Antikörper (F2)
Auf www.antikoerper-online.de finden Sie aktuell 228 Coagulation Factor II (thrombin) (F2) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Prothrombin Kits (123) und Prothrombin Proteine (50) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 409 Prothrombin Produkte verfügbar.
Synonyme:
AA959438, AI255193, AI327365, C1sa, Cf-2, Cf2, F2, FII, HTRA, HTRA1, prothrombin, PT, RPRGL2, THPH1, thrombin, wu:fb57c10, wu:fd42e09, wu:fd59d01, zgc:66319

Meistgesuchte Reaktivitäten zu anti-Prothrombin (F2) Antikörper

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Am meisten referenzierte anti-Prothrombin Antikörper

  1. Human Monoclonal Prothrombin Primary Antibody für WB - ABIN394859 : Ikejiri, Wada, Sakamoto, Ito, Nishioka, Nakatani, Tsuji, Yamada, Nakamura, Ito, Nobori: The association of protein S Tokushima-K196E with a risk of deep vein thrombosis. in International journal of hematology 2010 (PubMed)
    Zeige alle 5 Referenzen für 394859

  2. Human Monoclonal Prothrombin Primary Antibody für EIA, WB - ABIN954322 : Kazama, Pastuszyn, Wildgoose, Hamamoto, Kisiel: Isolation and characterization of proteolytic fragments of human factor VIIa which inhibit the tissue factor-enhanced amidolytic activity of factor VIIa. in The Journal of biological chemistry 1993 (PubMed)
    Zeige alle 3 Referenzen für 954322

  3. Human Monoclonal Prothrombin Primary Antibody für EIA, WB - ABIN954323 : Bharadwaj, Iino, Kontoyianni, Smith, Foster, Kisiel: Factor VII central. A novel mutation in the catalytic domain that reduces tissue factor binding, impairs activation by factor Xa, and abolishes amidolytic and coagulant activity. in The Journal of biological chemistry 1997 (PubMed)
    Zeige alle 3 Referenzen für 954323

  4. Cow (Bovine) Polyclonal Prothrombin Primary Antibody für IHC, WB - ABIN2776976 : Rossi, Za, Ciminello, Leone, De Stefano: The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophilia. in Thrombosis and haemostasis 2008 (PubMed)

  5. Human Polyclonal Prothrombin Primary Antibody für IHC, ELISA - ABIN1583288 : Fritze, Zhang, Li, Chai, Mulholland: Thrombin mediates vagal apoptosis and dysfunction in inflammatory bowel disease. in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2014 (PubMed)

Weitere Antikörper gegen Prothrombin Interaktionspartner

Zebrafish Coagulation Factor II (thrombin) (F2) Interaktionspartner

  1. Prothrombin morpholino-injected zebrafish embryos yielded an early phenotype exhibiting severe abnormalities that later showed occasional bleeding

Rhesus Monkey Coagulation Factor II (thrombin) (F2) Interaktionspartner

  1. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

Mouse (Murine) Coagulation Factor II (thrombin) (F2) Interaktionspartner

  1. These findings imply that a thrombin-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes.

  2. mutations were introduced into the endogenous fII gene, resulting in expression of prothrombin carrying 3 amino acid substitutions (R157A, R268A, and K281A) to limit activation events to yield only fIIa(Meizothrombin) Homozygous fII(MZ) mice are viable, express fII levels comparable with fII(Wild type) mice, and have reproductive success.

  3. Biglycan (zeige BGN Antikörper) plays a protective role during the progression of atherosclerosis in ApoE (zeige APOE Antikörper)-deficient mice by inhibiting thrombin generation.

  4. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha (zeige GP1BA Antikörper)-binding and heparin-binding site of thrombin

  5. thrombin/PAR-1 (zeige MARK2 Antikörper) interaction regulated MCP-1 (zeige CPT1B Antikörper), TF, MCSF (zeige CSF1 Antikörper) and IL-6 (zeige IL6 Antikörper) production.

  6. Observations illustrate the role of thrombin as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin (zeige SERPINC1 Antikörper) nanoparticle therapeutics.

  7. Thrombin-PAR1 (zeige F2R Antikörper) signaling, via nitric oxide and EPCR (zeige PROCR Antikörper), promotes hematopoietic stem cell (HSC (zeige FUT1 Antikörper)) mobilization.

  8. Primary tumor growth by colon cancer cells was reduced by reduction of circulating prothrombin. There were lower mitotic indices and invasiveness. This growth relied upon 2 targets of thrombin-mediated proteolysis, protease: PAR-1 and fibrinogen.

  9. Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase C epsilon.

  10. thrombin/PAR1 (zeige F2R Antikörper) pathway as a novel target for developing therapeutic strategies to restore synaptic function in the acute phase of ischemic stroke.

Human Coagulation Factor II (thrombin) (F2) Interaktionspartner

  1. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII (zeige F8 Antikörper) by thrombin has been presented.

  2. These studies clarify the role of PKCdelta (zeige PKCd Antikörper) in endothelial cell cytoskeleton regulation.

  3. Findings indicate functional effects of thrombin allostery and suggest that individual active site-directed thrombin inhibitors uniquely modulate exosite function.

  4. Acute Coronary Syndrome patients had an enhanced prothrombotic profile, demonstrated by an increased thrombin generation potential, factor XIa and D-dimer levels.

  5. we have found a novel homozygous mutation (p.Tyr510Asp) in the exon 13 of prothrombin gene in a Chinese proband. The mutation is responsible for the prothrombin deficiency reported here. Identification of the prothrombin deficiency in this family allowed mutation-specific prenatal screening.

  6. Individuals suffering from relapsing-remitting and secondary progressive multiple sclerosis had significantly higher prothrombin and factor X levels than healthy donors, whereas levels were unchanged in primary progressive MS and neuromyelitis optica patients.

  7. Prothrombin loading of vascular smooth muscle cell-derived exosomes regulates coagulation and calcification.

  8. Case Reports: prothrombin Padua 2 induces antithrombin (zeige SERPINC1 Antikörper) resistance and is associated with an increased risk of venous thromboembolism. Codon 596 (CGG) of prothrombin is a hot spot for mutations, which constitute a new and relatively frequent cause of inherited thrombophilia.

  9. Thrombin cleavage sites were mapped to the Duffy binding-like delta1 (DBLdelta1) domain and interdomains 1 and 2 in the PfEMP1 of the parasite line IT4var19.

  10. Furthermore, thrombin treatment of the inflammatory matrix leads to dissolution of HC-HA cable structures and abolishes leukocyte adhesion. These data establish a novel mechanism whereby thrombin cleavage of HC1 regulates the adhesive properties of an inflammatory HA matrix.

Cow (Bovine) Coagulation Factor II (thrombin) (F2) Interaktionspartner

  1. the weaker rapid interaction between prothrombin and membranes is the most important in vivo when considering the activation of prothrombin at the cell surface.

  2. novel pyranosic sulfated (zeige SULF1 Antikörper) arabinan Ab1 exerts its anticoagulant activity on thrombin by a mechanism different from those found previously for other sulfated (zeige SULF1 Antikörper) polysaccharides and glycosaminoglycans

  3. Exogenous delivery of thrombin enhances microvascular collateral development in response to ischemic insult, and accelerates tissue reperfusion.

  4. the signaling pathways of MAPK (zeige MAPK1 Antikörper), MSK1 (zeige RPS6KA5 Antikörper), and NF-kappaB (zeige NFKB1 Antikörper) play important roles in thrombin-induced iNOS (zeige NOS2 Antikörper) expression in alveolar macrophages

  5. High glucose enhances smooth muscle cell responsiveness to thrombin through transcriptional upregulation of PAR-4, mediated via PKC and NFkappaB.

  6. Thrombin induces a sustained contraction in the normal pulmonary artery, by activating PAR(1 (zeige F2R Antikörper)) and thereby increasing the sensitivity of the myofilament to Ca(2 (zeige CA2 Antikörper)+).

  7. kinetic and structural analysis of interactions between thrombin and the Factor XIII (zeige UGDH Antikörper) activation peptide

  8. analysis of staphylocoagulase-mediated bovine prothrombin activation

  9. thrombin and factor Xa (zeige F10 Antikörper) diffusion along the heparin molecule explains the effects of extended heparin chain lengths

  10. A comparison of recombinant thrombin to bovine thrombin as a hemostatic ancillary in patients undergoing peripheral arterial bypass and arteriovenous graft procedures.

Pig (Porcine) Coagulation Factor II (thrombin) (F2) Interaktionspartner

  1. thrombin stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (zeige UGDH Antikörper) and by receptor-mediated up-regulation of factor XIII (zeige UGDH Antikörper) synthesis

  2. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

  3. In conclusion, thrombin activates pro-MMP-2 (zeige MMP2 Antikörper) in the absence of elevated pro-MMP-2 (zeige MMP2 Antikörper) expression and secretion in CSMCs, and thrombin induces CSMC mitogenesis involving its action on MMP-2 (zeige MMP2 Antikörper)

  4. Thrombin stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (zeige F2R Antikörper), RhoA (zeige RHOA Antikörper), and myocardin (zeige MYOCD Antikörper).

Prothrombin (F2) Antigen-Profil

Beschreibung des Gens

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Alternative names and synonyms associated with Prothrombin (F2)

  • coagulation factor II (thrombin) (f2) Antikörper
  • coagulation factor II (thrombin) (F2) Antikörper
  • cell division cycle 34 (Cdc34) Antikörper
  • chymase 1, mast cell (CMA1) Antikörper
  • coagulation factor II (F2) Antikörper
  • complement component 1, s subcomponent (C1s) Antikörper
  • HtrA serine peptidase 1 (Htra1) Antikörper
  • HtrA serine peptidase 2 (HTRA2) Antikörper
  • melanoma antigen family B, 17-like (LOC783975) Antikörper
  • prothrombin-like (LOC100856539) Antikörper
  • serine protease (HTRA) Antikörper
  • THROMBIN protein (THROMBIN) Antikörper
  • AA959438 Antikörper
  • AI255193 Antikörper
  • AI327365 Antikörper
  • C1sa Antikörper
  • Cf-2 Antikörper
  • Cf2 Antikörper
  • F2 Antikörper
  • FII Antikörper
  • HTRA Antikörper
  • HTRA1 Antikörper
  • prothrombin Antikörper
  • PT Antikörper
  • RPRGL2 Antikörper
  • THPH1 Antikörper
  • thrombin Antikörper
  • wu:fb57c10 Antikörper
  • wu:fd42e09 Antikörper
  • wu:fd59d01 Antikörper
  • zgc:66319 Antikörper

Bezeichner auf Proteinebene für F2

prothrombin , cell division cycle 34 homolog , serine protease , ubiquitin-conjugating enzyme Cdc34 , ubiquitin-conjugating enzyme E2 R1 , alpha-chymase , chymase , mast cell chymase , mast cell protease I , coagulation factor 2 , thrombin , prepro-coagulation factor II , prothrombin B-chain , C1 esterase , complement C1s-A subcomponent , complement component 1 subcomponent s-A , complement component C1SA

GENE ID SPEZIES
325881 Danio rerio
712729 Macaca mulatta
299602 Rattus norvegicus
490628 Canis lupus familiaris
14061 Mus musculus
29251 Rattus norvegicus
2147 Homo sapiens
280685 Bos taurus
100144442 Sus scrofa
395306 Gallus gallus
100725988 Cavia porcellus
100307041 Ovis aries
50908 Mus musculus
100716225 Cavia porcellus
395990 Gallus gallus
783975 Bos taurus
100856539 Canis lupus familiaris
100008705 Oryctolagus cuniculus
100009146 Oryctolagus cuniculus
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