anti-SRC (SRC) Antikörper

Bezeichnung:
anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) Antikörper (SRC)
Auf www.antikoerper-online.de finden Sie aktuell 451 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antikörper von 30 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SRC Proteine (22) und SRC Kits (20) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 519 SRC Produkte verfügbar.
Synonyme:
ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b

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Am meisten referenzierte anti-SRC Antikörper

  1. Human Polyclonal SRC Primary Antibody für WB - ABIN1881832 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. in Cell stem cell 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881832

  2. Human Polyclonal SRC Primary Antibody für FACS, IF - ABIN1881833 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881833

  3. Human Polyclonal SRC Primary Antibody für ICC, IF - ABIN408484 : Yilmaz, Oztay, Kayalar: Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice. in Growth factors (Chur, Switzerland) 2016 (PubMed)
    Zeige alle 4 Referenzen für 408484

  4. Human Monoclonal SRC Primary Antibody für IF, WB - ABIN387822 : Chen, Li, Zhang, Yi, Chen, Wang, Zhang: Src-stimulated IRTKS phosphorylation enhances cell migration. in FEBS letters 2011 (PubMed)
    Zeige alle 2 Referenzen für 387822

  5. Human Polyclonal SRC Primary Antibody für IHC, ELISA - ABIN1533006 : Xu, Harrison, Eck: Three-dimensional structure of the tyrosine kinase c-Src. in Nature 1997 (PubMed)
    Zeige alle 2 Referenzen für 1533006

  6. Human Polyclonal SRC Primary Antibody für IHC, ELISA - ABIN1531972 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. in Cell 2005 (PubMed)
    Zeige alle 2 Referenzen für 1531972

  7. Human Polyclonal SRC Primary Antibody für IHC, ELISA - ABIN1532080 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  8. Cow (Bovine) Polyclonal SRC Primary Antibody für WB - ABIN2779668 : Pechkovsky, Scaffidi, Hackett, Ballard, Shaheen, Thompson, Thannickal, Knight: Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen SRC Interaktionspartner

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

  1. PTPN2 (zeige PTPN2 Antikörper) is a positive regulator of lipopolysaccharide-induced inflammatory response by enhancing the activity of Src through targeting the inhibitory phosphor-tyrosine527 of Src.

  2. demonstrated that both IL-10 (zeige IL10 Antikörper) and TGF-beta (zeige TGFB1 Antikörper) upregulated TIM-3 (zeige HAVCR2 Antikörper) surface expression on dendritic cells via a common signaling pathway that involved sequential activation of c-Src and Bruton's tyrosine kinase (zeige BTK Antikörper)

  3. Results suggest that interleukin-6 (IL-6 (zeige IL6 Antikörper)) increases VEGF-C (zeige VEGFC Antikörper) induction and lymphangiogenesis may involve, at least in part, Src-FAK (zeige PTK2 Antikörper)-STAT3 (zeige STAT3 Antikörper) cascade in lymphatic endothelial cells (LECs).

  4. Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line has been reported.

  5. Data show that the essential oil (EO) decreased focal adhesion and invadopodia formation which was accompanied by a drastic downregulation of focal adhesion kinase (FAK) and proto-oncogene protein Src.

  6. miR (zeige MLXIP Antikörper)-222-3p serves as an inhibitor of osteoclastogenesis and c-Src mediates its inhibition of cathepsin K (zeige CTSK Antikörper) and TRAP.

  7. results suggest that LPS (zeige TLR4 Antikörper)-stimulated macrophage mediators attenuate both FAK (zeige PTK2 Antikörper) and Src activations in osteoblast, suggesting a novel role for TNFalpha (zeige TNF Antikörper) on osteoblast performance

  8. Src has a role in priming Pyk2 (zeige PTK2B Antikörper) (but not FAK (zeige PTK2 Antikörper)) phosphorylation and subsequent activation downstream of integrins

  9. Heritable pulmonary arterial hypertension (PAH) results from increased SRC activation, cellular contraction, and vascular resistance, but antagonism of HTR2B prevents SRC phosphorylation and development of PAH.

  10. Periodic axial motility of epithelial basal cell projections is controlled by c-Src.

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (zeige TMOD4 Antikörper) (CP) alphabeta heterodimer, which regulates actin (zeige ACTB Antikörper) filament (F-actin (zeige ACTB Antikörper)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (zeige MAPK8 Antikörper) activation.

  6. Dumbfounded/Neph1 (zeige NEPH1 Antikörper), a key diaphragm constituent, is a target of the Src kinase (zeige CSK Antikörper) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (zeige NEPH1 Antikörper) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A (zeige PPP2R2B Antikörper)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (zeige ACTB Antikörper) formation and Jun kinase (zeige MAPK9 Antikörper) activation in plasmatocytes.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

  1. Results indicate Src homology 3 (SH3) domain-binding glutamic acid-rich-like protein (SH3BGRL) in driving tumor metastasis through c-Src activation, and suggests that hSH3BGRL mutation status could be relevant to cancer diagnosis and therapy.

  2. overexpression of syndecan-1 confers to B-LCs an increased capacity to migrate in response to Tat, owing to a switch from a CXCR4/G-protein/Rac to a syndecan-1/alphavbeta3/pp60src/pp125FAK signal transduction pathway that depends on the formation of a complex in which syndecan-1 interacts with Tat via its HS-chains, with alphavbeta3 via its core protein ectodomain and with pp60src via its intracellular tail

  3. the direct binding of ERalpha (zeige ESR1 Antikörper)-36 to ERK2 (zeige MAPK1 Antikörper) prevents its dephosphorylation by MKP3 (zeige DUSP6 Antikörper) and enhances the downstream signaling. These findings improve our understanding of the regulation of non-genomic estrogen signaling and open new avenues for personalized therapeutic approaches targeting Src or MEK (zeige MAP2K1 Antikörper) in ERalpha (zeige ESR1 Antikörper)-36-positive patients.

  4. Csk (zeige CSK Antikörper) induced phosphorylation of Src at tyrosine 530.

  5. regulation of Src activation and translocation

  6. SDCBP (zeige SDCBP Antikörper) might be an important marker for identifying Triple negative breast cancer cases that are suitable for dasatinib therapy.

  7. Restoring miR (zeige MLXIP Antikörper)-34a expression resulted in down-regulation of c-SRC and phosphorylated (Tyr416) c-SRC protein in K-562 cells, which consequently triggered suppression of the RAF (zeige RAF1 Antikörper)/MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper) signaling pathway to decrease cell proliferation.

  8. This study suggests PRL-3 and SFKs are key mediators of the IL6 (zeige IL6 Antikörper)-driven signaling events.

  9. the N-terminus of survivin (zeige BIRC5 Antikörper) is a mitochondrial-targeting sequence that regulates Src.

  10. These results suggest that the activation of endogenous levels of SFK renders the endothelial barrier more susceptible to low, physiologic doses of TNF-alpha (zeige TNF Antikörper) through activation of p38 (zeige CRK Antikörper) which leads to a loss of endothelial tight junctions.

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

  1. RhoA (zeige RHOA Antikörper) and membrane fluidity mediates the spatially polarized Src/FAK (zeige PTK2 Antikörper) activation in response to shear stress.

  2. AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.

  3. The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.

  4. src has a role in activation of 5'-AMP (zeige TMPRSS5 Antikörper)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  5. results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network

  6. These results suggest that TGF-beta1 (zeige TGFB1 Antikörper)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (zeige PTK2 Antikörper)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

  1. The findings are consistent with previous studies that indicate a link between Na,K-ATPase (zeige ATP1A1 Antikörper) activity and SFK signaling.

  2. Src kinase (zeige CSK Antikörper) mediates hypoxia-induced caspase-1 (zeige CASP1 Antikörper) activation in the cerebral cortex of newborn piglets

  3. Expression of mutant alpha1 Na/K-ATPase (zeige ATP1A1 Antikörper) defective in conformational transition attenuates Src-mediated signal transduction

  4. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC Antigen-Profil

Beschreibung des Gens

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC) Antikörper
  • proto-oncogene tyrosine-protein kinase src (AaeL_AAEL002471) Antikörper
  • proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) Antikörper
  • Rous sarcoma oncogene (Src) Antikörper
  • Src oncogene at 64B (Src64B) Antikörper
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC) Antikörper
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Src) Antikörper
  • v-src sarcoma viral oncogene (SRC) Antikörper
  • ASV Antikörper
  • AW259666 Antikörper
  • c-Src Antikörper
  • C-src1 Antikörper
  • CG7524 Antikörper
  • D-src Antikörper
  • D-Src64B Antikörper
  • Dmel\CG7524 Antikörper
  • DmHD-358 Antikörper
  • Dm SRC1 Antikörper
  • dsrc Antikörper
  • Dsrc64 Antikörper
  • Dsrc64B Antikörper
  • HD-358 Antikörper
  • MRE5 Antikörper
  • p60-Src Antikörper
  • PP60C-SCR Antikörper
  • pp60c-src Antikörper
  • SDR Antikörper
  • src Antikörper
  • SRC1 Antikörper
  • src64 Antikörper
  • SRC 64B Antikörper
  • src64b Antikörper

Bezeichner auf Proteinebene für SRC

proto-oncogene tyrosine-protein kinase SRC , proto-oncogene tyrosine-protein kinase src , neuronal proto-oncogene tyrosine-protein kinase Src , p60-Src , proto-oncogene c-Src , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , proto-oncogene tyrosine-protein kinase Src , protooncogene SRC, Rous sarcoma , tyrosine kinase pp60c-src , tyrosine-protein kinase SRC-1 , Rous sarcoma oncogene , c-Src , pp60c-src , tyrosine protein kinase c-src , tyrosine protein kinase pp60-c-src , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , src oncogene , v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , non-tyrosine protein kinase

GENE ID SPEZIES
458229 Pan troglodytes
5574802 Aedes aegypti
6043642 Culex quinquefasciatus
20779 Mus musculus
48973 Drosophila melanogaster
6714 Homo sapiens
83805 Rattus norvegicus
485864 Canis lupus familiaris
535742 Bos taurus
100154503 Sus scrofa
396442 Gallus gallus
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