IL21 Proteine (IL21)

Interleukin 21 Proteine (IL21)
Auf finden Sie aktuell 69 Interleukin 21 (IL21) Proteine von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL21 Antikörper (292) und IL21 Kits (81) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 455 IL21 Produkte verfügbar.
IL-21, Za11
alle Proteine anzeigen Gen GeneID UniProt
IL21 59067 Q9HBE4
IL21 60505 Q9ES17
IL21 365769 A3QPB9

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Am meisten referenzierte IL21 Proteine

  1. Human IL21 Protein expressed in Escherichia coli (E. coli) - ABIN2667504 : Coquet, Chakravarti, Smyth, Godfrey: Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Zeige alle 7 Referenzen für 2667504

  2. Human IL21 Protein expressed in Escherichia coli (E. coli) - ABIN2666654 : Eto, Lao, DiToro, Barnett, Escobar, Kageyama, Yusuf, Crotty: IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. in PLoS ONE 2011 (PubMed)
    Zeige alle 7 Referenzen für 2666654

  3. Mouse (Murine) IL21 Protein expressed in Escherichia coli (E. coli) - ABIN2666656 : Kaplan, Glosson, Stritesky, Yeh, Kinzfogl, Rohrabaugh, Goswami, Pham, Levy, Brutkiewicz, Blum, Cooper, Hangoc, Broxmeyer: STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis. in Blood 2011 (PubMed)
    Zeige alle 6 Referenzen für 2666656

  4. Human IL21 Protein expressed in Escherichia coli (E. coli) - ABIN2003099 : Sivakumar, Foster, Clegg: Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses. in Immunology 2004 (PubMed)
    Zeige alle 3 Referenzen für 2003099

  5. Human IL21 Protein expressed in Escherichia coli (E. coli) - ABIN413500 : Yoon, Zhang, Berner, Blom, Choi: Notch ligands expressed by follicular dendritic cells protect germinal center B cells from apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Zeige alle 2 Referenzen für 413500

Weitere Proteine zu IL21 Interaktionspartnern

Human Interleukin 21 (IL21) Interaktionspartner

  1. this study shows that induction of IL-21 (zeige IL17C Proteine) in T follicular helper cells is an indicator of influenza vaccine response in a HIV-infected pediatric cohort

  2. IL-21 (zeige IL17C Proteine) levels in rheumatoid arthritis synovial fluid were associated with matrix metalloproteinase (zeige MMP20 Proteine) (MMP)-1 (zeige MMP1 Proteine) and MMP-3 (zeige MMP3 Proteine).

  3. the elevated level of IL-2 (zeige IL2 Proteine)+ and IL-21 (zeige IL17C Proteine)+ T cells and a positive correlation between IL-21 (zeige IL17C Proteine)+ cells with clinical activity index in ulcerative colitis patients may contribute to the pathogenesis of disease.

  4. these results demonstrate a novel function for IL-21 (zeige IL17C Proteine) in tuning NK and CD4 (zeige CD4 Proteine)+ T cell interactions promoting a specific expansion of central memory lymphocytes

  5. Combined IL-21 (zeige IL17C Proteine)-primed polyclonal CTL plus CTLA4 (zeige CTLA4 Proteine) blockade controls refractory metastatic melanoma in a patient

  6. Our work suggests that IL-21 (zeige IL17C Proteine) regulates megakaryocyte development and platelet homeostasis. Thus, IL-21 (zeige IL17C Proteine) may link immune responses to physiological or pathological platelet-dependent processes.

  7. this study shows that Th17/Treg imbalance and increased IL-21 (zeige IL17C Proteine) are associated with liver injury in patients with chronic HBV infection

  8. The findings of the current study indicate an association between IL-21 (zeige IL17C Proteine)+TFH cells and disease activity. IL-21 (zeige IL17C Proteine)+TFH levels may prove to be a useful marker of disease activity in OA patients.

  9. IL-21 (zeige IL17C Proteine) is involved in the pathological development of Intervertebral Disc Degeneration and IL-21 (zeige IL17C Proteine) could aggravate IVD (zeige IVD Proteine) degeneration by stimulating TNF-alpha (zeige TNF Proteine) through the STAT (zeige STAT1 Proteine) signaling pathway

  10. Our findings suggest that the rs12508721T/C and rs2221903A/G polymorphisms of IL-21 (zeige IL17C Proteine) gene are associated with the susceptibility of HBV-related hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) and chronic HBV infection. The genetic variant may in fact cause protection against the HBV-related HCC (zeige FAM126A Proteine).

Mouse (Murine) Interleukin 21 (IL21) Interaktionspartner

  1. IL-6 (zeige IL6 Proteine) is identified as a master regulator of IL-21 in effector CD8 (zeige CD8A Proteine)(+) T cells.

  2. Our work suggests that IL-21 regulates megakaryocyte development and platelet homeostasis. Thus, IL-21 may link immune responses to physiological or pathological platelet-dependent processes.

  3. we identify novel distal regulatory elements in the mouse Il21 locus and demonstrate a dynamic long-range chromatin interaction between the Il21 promoter and these regulatory elements, which contributes to the regulated expression of IL-21

  4. this study shows that IL-21 acts as a potent inhibitor of a IL-17A (zeige IL17A Proteine)-producing T-cell subset during Mycobacterium bovis Bacillus infection

  5. IL-21 may play an important role in the pathogenesis of SSc (zeige CYP11A1 Proteine) as a Th17 effector cytokine, and IL-21 may induce the differentiation of Th17 cells in the BLM-induced systemic sclerosis mouse model via Il21R (zeige IL21R Proteine).

  6. The data of this study suggested that an increase in astrocyte-derived IL-21 expression in hippocampal subregions following KA-induced seizures may have potent regulatory effects on epileptogenesis.

  7. this study reveals a context-dependent role for IL-21 in sustaining effector phenotype CD8 (zeige CD8A Proteine) T cells and influencing their migratory properties, accumulation, and functions.

  8. Dysregulated development of IL-17 (zeige IL17A Proteine)- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORgammat.

  9. results demonstrate that, in the setting of lupus-like CD4 (zeige CD4 Proteine) T cell-driven B cell hyperactivity, IL-21 signaling on Ag-specific donor CD8 (zeige CD8A Proteine) T cells is critical for CTL effector maturation whereas a lack of IL-21R (zeige IL21R Proteine) downregulates CTL responses that would otherwise limit B cell hyperactivity and autoantibody production

  10. Gene expression analyses of angioimmunoblastic T-cell lymphoma (AITL), showed that essentially all cases expressed elevated levels of transcripts for IL21, IL21R (zeige IL21R Proteine), and a series of genes associated with TFH cell development and function.

Cow (Bovine) Interleukin 21 (IL21) Interaktionspartner

  1. The results revealed that the peak expression of IL6 (zeige IL6 Proteine) and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.

IL21 Protein Überblick

Protein Überblick

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with IL21

  • interleukin 21 (IL21)
  • interleukin 21 (Il21)
  • interleukin 21-like (LOC100344172)
  • IL-21 Protein
  • Za11 Protein

Bezeichner auf Proteinebene für Interleukin 21 Proteine (IL21)

interleukin-21 , interleukin-21 isoform , IL-21

59067 Homo sapiens
60505 Mus musculus
365769 Rattus norvegicus
378475 Bos taurus
100726049 Cavia porcellus
442935 Canis lupus familiaris
403123 Sus scrofa
100861248 Capra hircus
554218 Gallus gallus
100862657 Ovis aries
100344172 Oryctolagus cuniculus
Ausgewählte Anbieter für IL21 Proteine (IL21)
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