IL-13 Proteine (IL13)

Bezeichnung:
Interleukin 13 Proteine (IL13)
Auf www.antikoerper-online.de finden Sie aktuell 136 Interleukin 13 (IL13) Proteine von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL-13 Antikörper (368) und IL-13 Kits (162) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 685 IL-13 Produkte verfügbar.
Synonyme:
Il-13, IL13, L13, P600
alle Proteine anzeigen Gen GeneID UniProt
IL13 3596 P35225
IL13 16163 P20109
IL13 116553 P42203

Weitere Synonyme anzeigen

IL-13 Proteine (IL13) nach Spezies

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Am meisten referenzierte IL-13 Proteine

  1. Mouse (Murine) IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN2667457 : Harris, De Haro, Master, Keane, Roberts, Delgado, Deretic: T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. in Immunity 2007 (PubMed)
    Zeige alle 6 Referenzen für 2667457

  2. Human IL-13 Protein expressed in Human Cells - ABIN2002687 : Minty, Chalon, Derocq, Dumont, Guillemot, Kaghad, Labit, Leplatois, Liauzun, Miloux: Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. in Nature 1993 (PubMed)
    Zeige alle 5 Referenzen für 2002687

  3. Cynomolgus IL-13 Protein expressed in Human Cells - ABIN2003834 : Sironi, Sciacca, Matteucci, Conni, Vecchi, Bernasconi, Minty, Caput, Ferrara, Colotta: Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. in Blood 1994 (PubMed)
    Zeige alle 5 Referenzen für 2003834

  4. Mouse (Murine) IL-13 Protein expressed in Human Cells - ABIN2007534 : Solymar, Agarwal, Bassing, Alt, Rao: A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. in Immunity 2002 (PubMed)
    Zeige alle 5 Referenzen für 2007534

  5. Human IL-13 Protein expressed in CHO Cells - ABIN2002689 : Monticelli, Solymar, Rao: Role of NFAT proteins in IL13 gene transcription in mast cells. in The Journal of biological chemistry 2004 (PubMed)
    Zeige alle 5 Referenzen für 2002689

  6. Human IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN2666703 : LaPorte, Juo, Vaclavikova, Colf, Qi, Heller, Keegan, Garcia: Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. in Cell 2008 (PubMed)
    Zeige alle 5 Referenzen für 2666703

  7. Mouse (Murine) IL-13 Protein expressed in Escherichia coli (E. coli) - ABIN1305069 : Doherty, Kastelein, Menon, Andrade, Coffman: Modulation of murine macrophage function by IL-13. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
    Zeige alle 3 Referenzen für 1305069

Weitere Proteine zu IL-13 Interaktionspartnern

Human Interleukin 13 (IL13) Interaktionspartner

  1. These observations suggest that mechanical stretch may induce an influx of Ca(2 (zeige CA2 Proteine)+) and up-regulation of IL-13 and MMP-9 (zeige MMP9 Proteine) expression in 16HBE cells via activation of TRPC1 (zeige TRPC1 Proteine)

  2. Studies show that bronchoalveolar lavage fluid (BALF) soluble triggering receptor expressed on myeloid cells-1 (zeige TREM1 Proteine) (sTREM-1) levels do not discriminate between mild-to-moderate asthma and chronic obstructive pulmonary disease (COPD (zeige ARCN1 Proteine)), in contrast, the interleukin 6 (IL-6 (zeige IL6 Proteine))/interleukine 13 (IL-13) ratio measured in BALF effectively differentiated these two diseases.

  3. The presented data substantiate the hypothesis that claudin-18 (zeige CLDN18 Proteine) is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18 (zeige CLDN18 Proteine). These data also suggest that the loss of claudin-18 (zeige CLDN18 Proteine) is associated with increased sensitization to aeroantigens and airway responsiveness

  4. IL-12 pretreatment increased TCR-induced IFN-gamma, TNF-alpha, IL-13, IL-4 and IL-10 production. This suggests that prior exposure to IL-12 potentiates the TCR-induced release of a range of cytokines

  5. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (zeige IL4 Proteine) and IL-13, down-regulates matriptase (zeige ST14 Proteine) as well as prostasin (zeige PRSS8 Proteine) through phosphorylation of the transcriptional regulator STAT6 (zeige STAT6 Proteine)

  6. investigated the role of six potentially functional variants of the IL4 (zeige IL4 Proteine), IL13, and IL4R (zeige IL4R Proteine) genes in gastrointestinal cancer; both IL13 rs20541 and rs1800925 were not associated with gastrointestinal cancer risk for any of the genetic models and subgroup analyses [meta-analysis]

  7. IL13 in bronchial epithelial cells and bronchial alveolar lavage fluid, rather than RAD50 (zeige RAD50 Proteine), IL4 (zeige IL4 Proteine), or IL5 (zeige IL5 Proteine), is more likely to be the asthma susceptibility gene.

  8. We also found that the activation of H4R (zeige HRH4 Proteine) caused the release of IL-13 and RANTES (zeige CCL5 Proteine) on human mast cells.these data demonstrate that the H4R (zeige HRH4 Proteine) activates divergent signaling pathways to induce cytokine and chemokine (zeige CCL1 Proteine) production in human mast cells

  9. IL13 Arg130Gln genotypes can play a role in genetic susceptibility to allergy via regulation of serum total IgE levels and affecting IFN-gamma (zeige IFNG Proteine) gene expression.

  10. The GG genotype of IL-13 130A/G cytokine gene might be involved in the induced production of total IgE and IL-13 cytokine serum levels suggesting IL-13 may be important in the signalling of asthma.

Mouse (Murine) Interleukin 13 (IL13) Interaktionspartner

  1. findings suggest that a leukotriene B4 receptor-2-linked cascade plays a pivotal role in LPS/TLR4 (zeige TLR4 Proteine) signaling for IL-13 synthesis in mast cells, thereby potentially exacerbating allergic response.

  2. Study found IL-13 to be critically involved in the development of chemical-induced asthma, as shown by using IL-13 KO mice, and more specifically in the effector phase as confirmed by anti- IL-13 antibody treatment.

  3. these studies show that fibrosis, steatosis, cholestasis, and ductular reaction are simultaneously controlled but distinctly regulated by interleukin-13 signaling

  4. Our data support that impaired clearance of inhaled allergens triggering IL-13 production by multiple cell types in the airways plays an important role in the pathogenesis of type 2 airway inflammation and suggests therapeutic improvement of mucociliary clearance as a novel treatment strategy for children with allergen-induced asthma.

  5. this study shows that wild-type mice develop an eosinophilic Th2 airway disease in response to Alternaria alternata exposure, whereas IL-13-deficient mice exhibit a primarily neutrophilic response

  6. this study shows that IL-17A (zeige IL17A Proteine) contributes to asthma pathophysiology by increasing the capacity of IL-13 to activate intracellular signaling pathways, such as STAT6 (zeige STAT6 Proteine) activation

  7. RCM-1 (zeige TNNI3 Proteine) reduced IL-13 and STAT6 (signal transducer and activator of transcription 6 (zeige STAT6 Proteine)) signaling and prevented the expression of the STAT6 (zeige STAT6 Proteine) target genes Spdef and Foxa3 (zeige FOXA3 Proteine), which are key transcriptional regulators of goblet cell differentiation.

  8. IL-13 suppressed both the activation-induced apoptosis of CD4 (zeige CD4 Proteine)(+) T cells and the expression of p53 (zeige TP53 Proteine) and FasL (zeige FASL Proteine).

  9. We clearly show that miR (zeige MLXIP Proteine)-155 has a previously unknown direct regulatory role in the ILC2 subset that affects IL-33 (zeige IL33 Proteine) receptor expression, IL-33 (zeige IL33 Proteine) responsiveness, and IL-13 production as well as proliferation capability, possibly due to defects in GATA-3 (zeige GATA3 Proteine) function.

  10. The presented data substantiate the hypothesis that claudin-18 (zeige CLDN18 Proteine) is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18 (zeige CLDN18 Proteine). These data also suggest that the loss of claudin-18 (zeige CLDN18 Proteine) is associated with increased sensitization to aeroantigens and airway responsiveness

Cow (Bovine) Interleukin 13 (IL13) Interaktionspartner

  1. T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (zeige MMP1 Proteine) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.

IL-13 (IL13) Protein Überblick

Protein Überblick

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Alternative names and synonyms associated with IL-13 (IL13)

  • interleukin 13 (IL13)
  • interleukin 13 (Il13)
  • interleukin-13 (IL-13)
  • Il-13 Protein
  • IL13 Protein
  • L13 Protein
  • P600 Protein

Bezeichner auf Proteinebene für Interleukin 13 Proteine (IL13)

interleukin 13 , interleukin-13 , T-cell activation protein P600 , IL-13

GENE ID SPEZIES
100137221 Papio anubis
3596 Homo sapiens
16163 Mus musculus
100720118 Cavia porcellus
116553 Rattus norvegicus
396721 Sus scrofa
281247 Bos taurus
442990 Canis lupus familiaris
574325 Macaca mulatta
664707 Ovis aries
474361 Gallus gallus
449564 Pan troglodytes
100034113 Equus caballus
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