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Human IL-13 ELISA Kit für Sandwich ELISA - ABIN625011
Zurawski, de Vries: Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. in Immunology today 1994
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Mouse (Murine) IL-13 ELISA Kit für Sandwich ELISA - ABIN625137
Chung, Park, Park: Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice. in International immunopharmacology 2012
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Guinea Pig IL-13 ELISA Kit für Sandwich ELISA - ABIN364909
Maarsingh, Dekkers, Zuidhof, Bos, Menzen, Klein, Flik, Zaagsma, Meurs: Increased arginase activity contributes to airway remodelling in chronic allergic asthma. in The European respiratory journal 2011
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Rat (Rattus) IL-13 ELISA Kit für Sandwich ELISA - ABIN416369
Fang, Li, Liang, Xue, Liu, Yang, Gao, Jiang: Downregulation of SUMF2 gene in ovalbumin-induced rat model of allergic inflammation. in International journal of clinical and experimental pathology 2016
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Pig (Porcine) IL-13 ELISA Kit für Sandwich ELISA - ABIN415833
Baker, Romero, Bach, Strom, Gamelli, Majetschak: Systemic release of cytokines and heat shock proteins in porcine models of polytrauma and hemorrhage*. in Critical care medicine 2012
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Mouse (Murine) IL-13 ELISA Kit für Sandwich ELISA - ABIN411312
Wang, Shen, Li, Zhang, Luo, Zhong, Jiang, Shen: Enhanced expression of the decoy receptor IL-13Ralpha2 in macrophages of Schistosoma japonicum-infected mice. in Chinese medical journal 2009
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Human IL-13 ELISA Kit für Sandwich ELISA - ABIN1446080
Liu, Weir, Busse, Yang, Zhou, Emala, Li: The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-?B, STAT6, and HDAC2. in Phytotherapy research : PTR 2015
Dog (Canine) IL-13 ELISA Kit für Sandwich ELISA - ABIN414189
Majewska, Gajewska, Dembele, Maciejewski, Prostek, Jank: Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis. in BMC veterinary research 2016
Horse (Equine) IL-13 ELISA Kit für Sandwich ELISA - ABIN416685
Mariella, Castagnetti, Prosperi, Scagliarini, Peli: Cytokine levels in colostrum and in foals' serum pre- and post-suckling. in Veterinary immunology and immunopathology 2017
Mouse (Murine) IL-13 ELISA Kit für Sandwich ELISA - ABIN415504
Fang, Shi, Wu, Zhang, Zhong, Deng, Zhang, Xie: Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma. in Molecular immunology 2016
15LO1 inhibition (by short interfering RNA and chemical inhibitor) decreased IL-13-induced forkhead box protein A3 (FOXA3 (zeige FOXA3 ELISA Kits)) expression and enhanced FOXA2 (zeige FOXA2 ELISA Kits) expression. These changes were associated with reductions in both mucin 5AC and periostin (zeige POSTN ELISA Kits).
Clarithromycin suppressed IL-13-induced periostin (zeige POSTN ELISA Kits) production in human lung fibroblasts, in part by inhibiting STAT6 (zeige STAT6 ELISA Kits) phosphorylation. This suggests a novel mechanism of the immunomodulatory effect of clarithromycin in asthmatic airway inflammation and fibrosis.
Simvastatin reversed IL-13-suppressed adenosine deaminase (zeige ADA ELISA Kits) activity, leading to the down-regulation of adenosine signaling and inhibition osteopontin (zeige SPP1 ELISA Kits) expression through the direct inhibition of IL-13-activated STAT6 (zeige STAT6 ELISA Kits) pathway in COPD (zeige ARCN1 ELISA Kits).
Serum IL-5 (zeige IL5 ELISA Kits) and IL-13 are reliable biomarkers for the blood eosinophilia asthma phenotype.
IL-13 suppressed cyp27b1 (zeige CYP27B1 ELISA Kits) expression in CD14 (zeige NDUFA2 ELISA Kits)(+) cells. IL-13 increased expression of miR (zeige MLXIP ELISA Kits)-19a in CD14 (zeige NDUFA2 ELISA Kits)(+) cells. IL-13 suppresses cyp27b1 (zeige CYP27B1 ELISA Kits) expression in peripheral CD14 (zeige NDUFA2 ELISA Kits)(+) cells via up regulating miR (zeige MLXIP ELISA Kits)-19a expression.
Leptin (zeige LEP ELISA Kits) knockdown suppressed MUC5AC production and secretion induced by IL-13 in human bronchial epithelial cells.
demonstrate a strong association between the ratio of Acinetobacter to Proteobacteria and IL-13 production and the probability of IL-13 production after allergen exposure. IL-13 concentrations in serum were also significantly correlated with the diversity of bacterial DNA. Together, these results underscore the relationship between immune responses to allergens and bacterial exposure during perinatal development.
These observations suggest that mechanical stretch may induce an influx of Ca(2 (zeige CA2 ELISA Kits)+) and up-regulation of IL-13 and MMP-9 (zeige MMP9 ELISA Kits) expression in 16HBE cells via activation of TRPC1 (zeige TRPC1 ELISA Kits)
Studies show that bronchoalveolar lavage fluid (BALF) soluble triggering receptor expressed on myeloid cells-1 (zeige TREM1 ELISA Kits) (sTREM-1) levels do not discriminate between mild-to-moderate asthma and chronic obstructive pulmonary disease (COPD (zeige ARCN1 ELISA Kits)), in contrast, the interleukin 6 (IL-6 (zeige IL6 ELISA Kits))/interleukine 13 (IL-13) ratio measured in BALF effectively differentiated these two diseases.
The presented data substantiate the hypothesis that claudin-18 (zeige CLDN18 ELISA Kits) is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18 (zeige CLDN18 ELISA Kits). These data also suggest that the loss of claudin-18 (zeige CLDN18 ELISA Kits) is associated with increased sensitization to aeroantigens and airway responsiveness
Data indicate that interleukin-33 (IL-33 (zeige IL33 ELISA Kits))-induced Interleukin-13 (IL-13) production by type-2 helper T cells (Th2 cells) Is dependent on epidermal growth factor receptor (EGFR (zeige EGFR ELISA Kits)) expression.
this study shows that environmental IL-13 plays a role in conditioning early thymic progenitors lineage choice, which would impact T cell development
IL-4 (zeige IL4 ELISA Kits) and IL-13 are required to effectively polarize macrophages/dendritic cells to an M2a phenotype and to promote recovery from acute kidney injury.
this study shows that ST2 (zeige SULT2A1 ELISA Kits) regulates early IL-13 production in fungus-induced allergic airway inflammation
These observations suggest that IL-4 (zeige IL4 ELISA Kits) and IL-13 likely operate through the Heteroreceptor and influence Th17 cells to convert to Th1 (zeige HAND1 ELISA Kits) cells and to acquire increased sensitivity to suppression, leading to control of immune-mediated CNS inflammation.
MIF (zeige MIF ELISA Kits)-deficient mice have reduced Nippostrongylus brasiliensis burden and mounted an enhanced type 2 immune response, including increased Gata3 (zeige GATA3 ELISA Kits) expression and IL-13 production in the mesenteric lymph nodes
findings suggest that a leukotriene B4 receptor-2 (zeige LTB4R2 ELISA Kits)-linked cascade plays a pivotal role in LPS/TLR4 (zeige TLR4 ELISA Kits) signaling for IL-13 synthesis in mast cells, thereby potentially exacerbating allergic response.
Study found IL-13 to be critically involved in the development of chemical-induced asthma, as shown by using IL-13 KO mice, and more specifically in the effector phase as confirmed by anti- IL-13 antibody treatment.
these studies show that fibrosis, steatosis, cholestasis, and ductular reaction are simultaneously controlled but distinctly regulated by interleukin-13 signaling
Our data support that impaired clearance of inhaled allergens triggering IL-13 production by multiple cell types in the airways plays an important role in the pathogenesis of type 2 airway inflammation and suggests therapeutic improvement of mucociliary clearance as a novel treatment strategy for children with allergen-induced asthma.
T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (zeige MMP1 ELISA Kits) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
, T-cell activation protein P600