IFNG Proteine (IFNG)

Bezeichnung:
Interferon gamma Proteine (IFNG)
Auf www.antikoerper-online.de finden Sie aktuell 255 Interferon gamma (IFNG) Proteine von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IFNG Antikörper (1367) und IFNG Kits (441) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 2098 IFNG Produkte verfügbar.
Synonyme:
IFG, IFI, IFN-G, IFN-gamma, IFNG, IFNG2
alle Proteine anzeigen Gen GeneID UniProt
Ratte IFNG IFNG 25712 P01581
Maus IFNG IFNG 15978 P01580
IFNG 3458 P01579

Weitere Synonyme anzeigen

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Am meisten referenzierte IFNG Proteine

  1. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2018007 : Ealick, Cook, Vijay-Kumar, Carson, Nagabhushan, Trotta, Bugg: Three-dimensional structure of recombinant human interferon-gamma. in Science (New York, N.Y.) 1991 (PubMed)
    Zeige alle 5 Referenzen für 2018007

  2. Ferret IFNG Protein expressed in Human Cells - ABIN2008793 : Greenlund, Farrar, Viviano, Schreiber: Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). in The EMBO journal 1994 (PubMed)
    Zeige alle 4 Referenzen für 2008793

  3. Rat (Rattus) IFNG Protein expressed in Human Cells - ABIN2009352 : Bach, Aguet, Schreiber: The IFN gamma receptor: a paradigm for cytokine receptor signaling. in Annual review of immunology 1997 (PubMed)
    Zeige alle 4 Referenzen für 2009352

  4. Mouse (Murine) IFNG Protein expressed in Human Cells - ABIN2008201 : Rinderknecht, OConnor, Rodriguez: Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation. in The Journal of biological chemistry 1984 (PubMed)
    Zeige alle 4 Referenzen für 2008201

  5. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305087 : Farrar, Schreiber: The molecular cell biology of interferon-gamma and its receptor. in Annual review of immunology 1993 (PubMed)
    Zeige alle 3 Referenzen für 1305087

  6. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1047219 : Gray, Leung, Pennica, Yelverton, Najarian, Simonsen, Derynck, Sherwood, Wallace, Berger, Levinson, Goeddel: Expression of human immune interferon cDNA in E. coli and monkey cells. in Nature 1982 (PubMed)
    Zeige alle 3 Referenzen für 1047219

  7. Rat (Rattus) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN2666970 : De Maeyer, De Maeyer-Guignard: Interferon-gamma. in Current opinion in immunology 1992 (PubMed)
    Zeige alle 2 Referenzen für 2666970

  8. Mouse (Murine) IFNG Protein expressed in Escherichia coli (E. coli) - ABIN1305090 : Gray, Goeddel: Cloning and expression of murine immune interferon cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1983 (PubMed)
    Zeige alle 2 Referenzen für 1305090

  9. Human IFNG Protein expressed in HEK-293 Cells - ABIN2181249 : Derynck, Leung, Gray, Goeddel: Human interferon gamma is encoded by a single class of mRNA. in Nucleic acids research 1982 (PubMed)
    Zeige alle 2 Referenzen für 2181249

  10. Human IFNG Protein expressed in Escherichia coli (E. coli) - ABIN934917 : POGO, BRAWERMAN, CHARGAFF: New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis. in Biochemistry 1970 (PubMed)

Weitere Proteine zu IFNG Interaktionspartnern

Mouse (Murine) Interferon gamma (IFNG) Interaktionspartner

  1. identified IFNg, Neurturin (Nrtn (zeige NRTN Proteine)), and glial-derived neurotrophic factor (GDNF) as ligands with unexpected roles in promoting neurogenic differentiation (zeige NEUROD1 Proteine) of Neural Precursor Cells in vivo.

  2. Egr2 (zeige EGR2 Proteine) and 3 were essential to suppress Th1 (zeige HAND1 Proteine) differentiation in Th2 and Th17 conditions in vitro and also to control IFN-gamma-producing CD4 (zeige CD4 Proteine) and CD8 (zeige CD8A Proteine) T cells in response to virus infection

  3. studies identify the requirement of IFN-gamma stimulation as a mechanism for BC-CML and AML GVL resistance, whereas independence from IFN-gamma renders CP-CML more GVL sensitive, even with a lower-level alloimmune response.

  4. Results demonstrate that the influence of IFN-gamma on acute lymphoblastic leukemia progression may not be mediated by selection of nascent transformed cells but rather through a general suppressor of cytokine signaling (zeige CISH Proteine) -mediated reduction in B-cell precursor proliferation.

  5. The results indicate that interferon-gamma is critical for the initial priming and differentiation of cytotoxic T lymphocytes residing in the periphery to produce the most effect antitumor function within the eye.

  6. The authors showed the synergistic negative regulation of the pro-inflammatory cytokine interferon-gamma (IFNgamma) and beta3 integrin (zeige ITGB3 Proteine) signaling in murine hematopoietic stem cells function by a novel definitive phenotyping of hematopoietic stem cells.

  7. We revealed that in mouse mesenchymal stem cells IFN-gamma-induced immunoregulation is media (zeige STAT3 Proteine)ted by early phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3, which is significantly enhanced by an extracellular signal-regulated kinase 1/2-dependent mTOR inhibition, thereby promoting pSTAT1 nuclear translocation.

  8. data suggest that mPEG PV1 (zeige PLVAP Proteine)-Fab (zeige FANCB Proteine)' acts mainly on IFN-gamma-producing CD4 (zeige CD4 Proteine)+ T cells and emphasize that this specific CD28 (zeige CD28 Proteine) blockade strategy is a potential specific and alternative tool for the treatment of autoimmune disorders in the eye.

  9. this study showsthat the nature of the protective memory response depends closely on the route of infection and highlights the role of IFN-gamma-and IL-17RA (zeige IL17RA Proteine)-mediated responses in the control of mucosal infection by Brucella

  10. Study showed that the intraperitoneal administration of the exogenous cytokines IFN-gamma (to promote M1 microglia ) and IL-4 (zeige IL4 Proteine) (to promote M2 microglia) can correctly modulate the timing of the M1 to M2 ratio to affect epileptogenesis and to improve cognitive function in pilocarpine-induced status epilepticus.

Guinea Pig Interferon gamma (IFNG) Interaktionspartner

  1. Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 (zeige IL4 Proteine) ratio were significantly lower than those exposed to its low concentration.

Human Interferon gamma (IFNG) Interaktionspartner

  1. this study shows that genes associated with MAF (zeige MAF Proteine)-binding enhancers are suppressed in macrophages isolated from rheumatoid-arthritis patients, revealing a disease-associated signature of IFN-gamma-mediated repression

  2. This study presents preliminary evidence for the association between IFN +874 T/A, T/T, IL-10 (zeige IL10 Proteine) -1082 A/G genotypes, and hemophagocytic lymphohistiocytosis susceptibility in Chinese children

  3. Data suggest IFNG plays various roles in dynamics of inflammation in subjects with underlying autoimmunity modeled as "canonical" and "non-canonical" pathways; in canonical pathway, IFNG dimerizes and binds to IFNGR1 (zeige IFNGR1 Proteine) in IFNGR1 (zeige IFNGR1 Proteine)/IFNGR2 (zeige IFNGR2 Proteine) hetero-multimer; STAT (zeige STAT1 Proteine) transcription factors are involved in non-canonical pathway. (IFNG = interferon gamma; IFNGR (zeige IFNGR1 Proteine) = IFNG receptor; STAT (zeige STAT1 Proteine) = signal transducers and activators of transcription)

  4. High levels of IFNG is associated with lyme disease.

  5. observed inverse relationship between the circulating levels of IFN-gamma and IL-17 (zeige IL17A Proteine) together with the reduction in the levels of memory-like CD4 (zeige CD4 Proteine)+ T cells expressing IL-17 (zeige IL17A Proteine) in children with SMA (zeige SMN1 Proteine) may suggest possible relocation of these cells in the deeper tissues for their pathological effect

  6. Preliminary results demonstrate concordance between IFNG +874 A/A genotype and low expression of IFNG in the Warao indigenous population

  7. A sustained exposure to IFN-gamma in human mesenchymal stem cells led to inhibition of STAT3 (zeige STAT3 Proteine) activity.

  8. Using a human oligodendroglioma (HOG (zeige MAPK14 Proteine)) cell line as a model, here we show that exosomes derived from TNF-a (zeige TNF Proteine)-treated "donor" cells, while being mildly toxic to fresh cultures (similar to individual cytokines), induce enhanced cell death when added to IFN-g-primed target cultures in a fashion resembling the effect of cytokine combination

  9. Fungus of the Sporothrix schenckii complex can produce skin lesions, commonly lymphocutaneous (LC) and fixed (F) forms of sporotrichosis. LC lesions present higher IL-10 (zeige IL10 Proteine) expression which could be related to regulatory mechanisms for compensating the tissue injury, however favoring fungal persistence in the lesions. Surprisingly, there were no differences in systemic and in situ IFN- gamma expression between CL and F pa...

  10. IL17A (zeige IL17A Proteine), IFNG, and FOXP3 (zeige FOXP3 Proteine) are increased in plaque-type psoriasis

Pig (Porcine) Interferon gamma (IFNG) Interaktionspartner

  1. The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR (zeige NR1I2 Proteine).

  2. Translational control of IL-18 (zeige IL18 Proteine) expression by its 5'-UTR limits production of IL-18 (zeige IL18 Proteine), resulting in restricted expression of mRNA and protein IFN-gamma in this model of crescentic glomerulonephritis(GN). Might amplify CD8 (zeige CD8A Proteine)+-mediated macrophage-dependent GN.

  3. selective changes in immature crypt cells induced by IFN-gamma bound to extracellular matrix could contribute to inappropriate responsiveness to commensal bacteria in inflammatory bowel diseases

  4. A functional single nucleotide polymorphism is reported in the coding region of IFN-gamma cDNA that markedly reduces antiviral activity of the IFN-gamma protein.

  5. The expression of IFN-gamma in recombiannt Lactococcus lactis as a tool for investigating downregulation of allergic predisposition of pigs to experimental food allergy is reported.

Cow (Bovine) Interferon gamma (IFNG) Interaktionspartner

  1. The expression of multiple toll (zeige TLR4 Proteine)-like receptors, interferon-gamma, and interleukin-12 (IL-12 (zeige IL12A Proteine)) in cattle with low and high proviral loads of bovine leukemia virus are reported.

  2. Diet-driven interferon-gamma enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagy.

  3. Data suggest that luteolytic factors (such as IFNG, tumor necrosis factor alpha (zeige TNF Proteine), and PGF2a) control expression of MMP1 (zeige MMP1 Proteine), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels.

  5. These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma occurring after parturition and an increase in IL-4 (zeige IL4 Proteine) production before calving.

  6. Genetic characterization of IFNG gene was done in resistant and susceptible animals of Sahiwal cattle (n = 95) and Friesian (n = 92).

  7. Data suggest that activation of gammadelta T cells to IFN-gamma production, NK cell-like killing plays a pivotal role in controlling virus infection.

  8. The differential expression levels of IFN-gamma mRNA between cattle and buffalo could be due to a conserved 4 base (GTCT) deletion in the promoter region of buffalo.

  9. SNPs in IFNG, IFNGR1 (zeige IFNGR1 Proteine) and R2, IL22 (zeige IL22 Proteine), and IL22RA1 (zeige IL22RA1 Proteine) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

  10. Nuclear localization sequence of bovine gamma-interferon provides translocation of recombinant protein to yeast Pichia pastoris cell nucleus

Horse (Equine) Interferon gamma (IFNG) Interaktionspartner

  1. These results indicate that in equine corpus luteum, cytokines TNF (zeige TNF Proteine), IFNG and FASL (zeige FASL Proteine) regulate nitric oxide activity, via eNOS (zeige NOS3 Proteine) expression modulation.

  2. IFN-gamma expression in foals appears to be controlled by DNA methylation (zeige HELLS Proteine) in the promoter region of Ifng. The age-associated demethylation of the DNA in foals may be induced by exposure to environmental antigens and their effect on lymphoproliferation (zeige FAS Proteine).

  3. These data show the presence of cytokines TNF (zeige TNF Proteine) and IFNG, and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.

  4. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (zeige TH1L Proteine) biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 (zeige IL10 Proteine) production by T cells is mature.

Rhesus Monkey Interferon gamma (IFNG) Interaktionspartner

  1. IFNgamma expression in colonic epithelial cells was regulated by TGFB1 (zeige TGFB1 Proteine).

  2. Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.

  3. Data show that viral set-point in simian immunodeficiency virus diseasewas is associated with expression of interferon gamma -stimulated genes.

  4. Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine interferon-gamma.

Chimpanzee Interferon gamma (IFNG) Interaktionspartner

  1. CD3 (zeige CD3 Proteine)(-) CD8 (zeige CD8A Proteine)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma, and that IL-15 (zeige IL15 Proteine) elicits IFN-gamma production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15 (zeige IL15 Proteine), CD8 (zeige CD8A Proteine) antigen, IFN-gamma]

IFNG Protein Überblick

Protein Überblick

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.

Alternative names and synonyms associated with IFNG

  • interferon gamma (Ifng)
  • interferon gamma (IFNG)
  • interferon gamma-like (LOC101337436)
  • interferon, gamma (IFNG)
  • interferon, gamma (Ifng)
  • IFG Protein
  • IFI Protein
  • IFN-G Protein
  • IFN-gamma Protein
  • IFNG Protein
  • IFNG2 Protein

Bezeichner auf Proteinebene für Interferon gamma Proteine (IFNG)

IFN-gamma , gamma interferon , interferon-gamma , interferon, gamma , interferon gamma , immune interferon , interferon-gama , boIFNG , interferon gamma type 2 , Interferon gamma , gamma-interferon , IFN gamma

GENE ID SPEZIES
25712 Rattus norvegicus
15978 Mus musculus
403801 Canis lupus familiaris
100379568 Cavia porcellus
101337436 Tursiops truncatus
3458 Homo sapiens
396991 Sus scrofa
396054 Gallus gallus
493965 Felis catus
281237 Bos taurus
100034181 Equus caballus
100860815 Capra hircus
443396 Ovis aries
101790439 Anas platyrhynchos
100008602 Oryctolagus cuniculus
574282 Macaca mulatta
100388952 Callithrix jacchus
101422877 Dasypus novemcinctus
100462659 Ailuropoda melanoleuca
101825431 Mesocricetus auratus
449517 Pan troglodytes
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