anti-GLI1 (GLI1) Antikörper

anti-Zinc Finger Protein GLI1 Antikörper (GLI1)
Auf finden Sie aktuell 193 Zinc Finger Protein GLI1 (GLI1) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GLI1 Kits (10) und GLI1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 220 GLI1 Produkte verfügbar.
AV235269, Gli, Gli-1, gli1.1, Zfp-5, Zfp5

Meistgesuchte Reaktivitäten zu anti-GLI1 (GLI1) Antikörper

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anti-Human GLI1 Antikörper:

anti-Rat (Rattus) GLI1 Antikörper:

anti-Mouse (Murine) GLI1 Antikörper:

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Am meisten referenzierte anti-GLI1 Antikörper

  1. Human Polyclonal GLI1 Primary Antibody für ChIP, ELISA - ABIN153487 : Ghali, Wong, Green, Tidman, Quinn: Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin. in The Journal of investigative dermatology 1999 (PubMed)
    Zeige alle 28 Referenzen für 153487

  2. Cow (Bovine) Polyclonal GLI1 Primary Antibody für WB - ABIN2779593 : Rahnama, Shimokawa, Lauth, Finta, Kogerman, Teglund, Toftgård, Zaphiropoulos: Inhibition of GLI1 gene activation by Patched1. in The Biochemical journal 2006 (PubMed)
    Zeige alle 9 Referenzen für 2779593

  3. Human Polyclonal GLI1 Primary Antibody für IF (p), IHC (p) - ABIN673374 : Zhang, Zhu, Zhou, Gao, Yuan, Han: Serotonin receptor 2C and insulin secretion. in PLoS ONE 2013 (PubMed)
    Zeige alle 6 Referenzen für 673374

  4. Human Polyclonal GLI1 Primary Antibody für ICC, IF - ABIN4314249 : Jalili, Mertz, Romanov, Wagner, Kalthoff, Stuetz, Pathria, Gschaider, Stingl, Wagner: NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo. in PLoS ONE 2013 (PubMed)
    Zeige alle 4 Referenzen für 4314249

  5. Human Polyclonal GLI1 Primary Antibody für WB - ABIN265275 : Wang, Chan, Rothnagel: Letters to the editor: identification of polymorphic variants of the GLI1 oncogene. in The Journal of investigative dermatology 2000 (PubMed)
    Zeige alle 2 Referenzen für 265275

  6. Human Polyclonal GLI1 Primary Antibody für WB - ABIN4620372 : Kinzler, Ruppert, Bigner, Vogelstein: The GLI gene is a member of the Kruppel family of zinc finger proteins. in Nature 1988 (PubMed)

Weitere Antikörper gegen GLI1 Interaktionspartner

Human Zinc Finger Protein GLI1 (GLI1) Interaktionspartner

  1. The data described herein provide the first identification of a DYRK1A (zeige DYRK1A Antikörper)-mediated site of phosphorylation on GLI1 within its NLS (zeige ALDH1A2 Antikörper) and may serve as a valuable mechanism for further understanding Hh signaling modulation.

  2. Case Report: gastric pericytoma harboring the exceptionally rare translocation t(7;12) resulting in ACTB (zeige ACTB Antikörper)-GLI1 gene fusion.

  3. USP21 (zeige USP21 Antikörper) recruits and stabilises Gli1 at the centrosome.

  4. Gli1 expression was significantly correlated with T stage lymph node metastasis, and clinical stage of lung squamous cell carcinoma.

  5. Gli1 role in cell proliferation and differentiation

  6. Gli1 inhibitor GANT61 and SHH (zeige SHH Antikörper) siRNA synergistically enhanced cytotoxicity induced by itraconazole in MCF-7 cells.

  7. Hedgehog (zeige SHH Antikörper) pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.

  8. Our studies demonstrate an important role for smoothened (zeige SMO Antikörper) and glioma-associated oncogene homology-1 in gastric cancer and suggest inhibition of hedgehog (zeige SHH Antikörper) pathway as a novel and potent strategy to treat gastric cancer patients

  9. GANT61, which is a targeted inhibitor of Gli1 and Gli2 (zeige GLI2 Antikörper), decreased cell viability and promoted cell apoptosis. Thus, TGF-b1 induced EMT (zeige ITK Antikörper) in neuroblastoma (zeige ARHGEF16 Antikörper) cells to increase their migration. Specifically, EMT (zeige ITK Antikörper) induced by TGF-b1 in neuroblastoma (zeige ARHGEF16 Antikörper) cells did not depend on the Smad (zeige SMAD1 Antikörper) signaling pathway, and the transcription factor Gli participated in TGF-b1-induced EMT (zeige ITK Antikörper) independent of Smad (zeige SMAD1 Antikörper) signaling.

  10. Gli1 expression was detected in most ERM (zeige ETV5 Antikörper) specimens. Patients who had DR or OCT (zeige Plxna2 Antikörper) findings indicating chronic retinal insults showed higher Gli1 expression. Gli1 may have a role in the pathogenesis of ERM (zeige ETV5 Antikörper) after chronic retinal insults.

Cow (Bovine) Zinc Finger Protein GLI1 (GLI1) Interaktionspartner

  1. Data indicate that the expression levels of transcription factors Gli1 and Gli2 (zeige GLI2 Antikörper) in muscle were the lowest of the 13 tissues.

Xenopus laevis Zinc Finger Protein GLI1 (GLI1) Interaktionspartner

  1. Dzip1 (zeige DZIP1 Antikörper)-dependent stabilization of Spop (zeige SPOP Antikörper)/HIB is evolutionarily conserved and essential for proper regulation of Gli/Ci proteins in the Hh pathway.

  2. Zyxin (zeige ZYX Antikörper) inhibits Shh (zeige SHH Antikörper) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1

Zebrafish Zinc Finger Protein GLI1 (GLI1) Interaktionspartner

  1. Mutation of hmgcs1 (zeige HMGCS1 Antikörper) had no effect on Shh (zeige SHH Antikörper) signaling at 2 and 3 days post fertilization (dpf), but did result in a decrease in the expression of gli1, a known Shh (zeige SHH Antikörper) target gene, at 4 dpf, after morphological deficits in craniofacial development and chondrocyte differentiation were observed in hmgcs1 (zeige HMGCS1 Antikörper) mutants.

  2. a new mechanism of Gli transcription factor activation and implicate ARHGAP36 (zeige ARHGAP36 Antikörper) dysregulation in the onset and/or progression of GLI-dependent cancers.

  3. We show that Kif7 (zeige KIF7 Antikörper) interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 (zeige KIF7 Antikörper) in Drosophila.

  4. Gli1 has a Hh-independent role in many motoneurons and V3 domain cells in embryos that lack Hh signalling, but removal of Gli1 activity does not affect more dorsal neurons.

  5. These results reveal divergent requirements for Gli1 and Gli2 (zeige GLI2 Antikörper) in mouse and zebrafish and indicate that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 (zeige GLI2 Antikörper) has minor roles as a repressor or activator of Hh targets.

  6. Gli1 regulates the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl (zeige SGPL1 Antikörper)) factor activity.

Mouse (Murine) Zinc Finger Protein GLI1 (GLI1) Interaktionspartner

  1. USP21 (zeige USP21 Antikörper) recruits and stabilises Gli1 at the centrosome.

  2. High Gli1 expression is associated with leukemia.

  3. Sufu (zeige SUFUH Antikörper) is upregulated in active Shh (zeige SHH Antikörper) responding tissues and accompanies Gli activators translocating into and Gli repressors out of the nucleus.

  4. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  5. NANOG (zeige NANOG Antikörper) binds to GLI1 and GLI3 (zeige GLI3 Antikörper) proteins and represses Hedgehog (zeige SHH Antikörper)-mediated transcription.

  6. characterization of the contribution to remyelination of a subset of adult neural stem cells, identified by their expression of Gli1, a transcriptional effector of the sonic hedgehog (zeige SHH Antikörper) pathway

  7. the three GLI factors(GLI1, GLI2 (zeige GLI2 Antikörper), and GLI3 (zeige GLI3 Antikörper)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  8. Gli1, a known Ptch (zeige PTCH1 Antikörper) activator, preferentially bound the mutant Ptch (zeige PTCH1 Antikörper) locus in rhabdomyosarcoma.

  9. show that combined targeting of GLI and PI3K/AKT (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling can have a synergistic therapeutic effect in cells from a subgroup of chronic lymphocytic leukemia patients

  10. Beta-catenin (zeige CTNNB1 Antikörper) stabilization increases its physical interaction with Gli1.

GLI1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GLI1

  • GLI family zinc finger 1 (GLI1) Antikörper
  • GLI family zinc finger 1 (Gli1) Antikörper
  • GLI family zinc finger 1 (gli1) Antikörper
  • GLI-Kruppel family member 1 (gli1) Antikörper
  • GLI-Kruppel family member GLI1 (Gli1) Antikörper
  • AV235269 Antikörper
  • Gli Antikörper
  • Gli-1 Antikörper
  • gli1.1 Antikörper
  • Zfp-5 Antikörper
  • Zfp5 Antikörper

Bezeichner auf Proteinebene für GLI1

glioma-associated oncogene 1 , glioma-associated oncogene homolog 1 (zinc finger protein) , oncogene GLI , zinc finger protein GLI1 , GLI-Kruppel family member GLI1 , GLI family zinc finger 1, gene 1 , zinc finger DNA binding protein Gli-1 , detour , dtr , glioma-associated oncogene homolog , zinc finger protein 5

2735 Homo sapiens
481126 Canis lupus familiaris
517588 Bos taurus
100033937 Equus caballus
140589 Rattus norvegicus
396045 Gallus gallus
398350 Xenopus laevis
352930 Danio rerio
14632 Mus musculus
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