Syndecan 1 Proteine (SDC1)

Bezeichnung:
Syndecan 1 Proteine (SDC1)
Auf www.antikoerper-online.de finden Sie aktuell 41 Syndecan 1 (SDC1) Proteine von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Syndecan 1 Antikörper (398) und Syndecan 1 Kits (77) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 528 Syndecan 1 Produkte verfügbar.
Synonyme:
AA408134, AA409076, CD138, CG10497, CT27296, Dmel\\CG10497, dSdc, Dsyn, HSPG, l(2)10608, SDC, SDC1, Sstn, syd, syn, syn-1, Syn1, Synd, Synd1, SYNDECA, Syndecan, Syndecan-1, syndecan1, xSyn1, XSyndecan-1
alle Proteine anzeigen Gen GeneID UniProt
SDC1 6382 P18827
SDC1 20969 P18828
SDC1 25216 P26260

Weitere Synonyme anzeigen

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Am meisten referenzierte Syndecan 1 Proteine

  1. Human SDC1 Protein expressed in HEK-293 Cells - ABIN2180684 : Bhatt, Erdjument-Bromage, Tempst, Craik, Moasser: Adhesion signaling by a novel mitotic substrate of src kinases. in Oncogene 2005 (PubMed)
    Zeige alle 2 Referenzen für 2180684

  2. Human SDC1 Protein expressed in Escherichia coli (E. coli) - ABIN1098237 : Rawstron: Immunophenotyping of plasma cells. in Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2008 (PubMed)
    Zeige alle 2 Referenzen für 1098237

  3. Human SDC1 Protein expressed in Human Cells - ABIN2004277 : Zou, Chen, Zong, Ye, Tang, Meng, An, Zhang, Yang: Immunotherapy based on bispecific T-cell engager with hIgG1 Fc sequence as a new therapeutic strategy in multiple myeloma. in Cancer science 2015 (PubMed)

Weitere Proteine zu Syndecan 1 Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Syndecan 1 (SDC1) Interaktionspartner

  1. all detectable Sdc found at the NMJ is provided by the muscle, strongly suggesting a post-synaptic role for Sdc. both the cytoplasmic and extracellular domains of Sdc are required to promote synapse growth or to rescue Sdc loss of function.

  2. We conclude that Sdc cell autonomously regulates Slit/Robo2 signalling in tracheal cells to guarantee ordered directional migration and branch fusion.

  3. In this study, we provide evidence that Dlp (zeige DMD Proteine) and Sdc have both overlapping and distinct functions in axon guidance and in defining accurate patterns of axonal fasciculation within the lateral CNS neuropil

  4. Syndecan acting as a co-receptor for Slit in the Drosophila heart.

  5. Syndecan (Sdc) is critical for the fidelity of Slit repellent signaling at the midline of the Drosophila CNS.

  6. The heparan sulfate proteoglycan syndecan is an in vivo ligand for the Drosophila LAR (zeige PTPRF Proteine) receptor tyrosine phosphatase (zeige PTPRU Proteine).

  7. Dlp (zeige DMD Proteine), which lacks chondroitin sulfate (CS)modifications, participates in the transfer of Slit from its site of expression to the target cells, where CS-modified Sdc concentrates and presents the ligand.

Human Syndecan 1 (SDC1) Interaktionspartner

  1. A syndecan-1 level >/=40 ng/mL identified trauma patients with significantly worse outcomes, despite admission physiology similar to those without the condition.

  2. overexpression of syndecan-1 confers to B-LCs an increased capacity to migrate in response to Tat, owing to a switch from a CXCR4/G-protein/Rac to a syndecan-1/alphavbeta3/pp60src/pp125FAK signal transduction pathway that depends on the formation of a complex in which syndecan-1 interacts with Tat via its HS-chains, with alphavbeta3 via its core protein ectodomain and with pp60src via its intracellular tail

  3. MiR (zeige MLXIP Proteine)-331-3p-mediated miRNA maturation and enhanced epithelial-to-mesenchymal transition via effects on TGF-beta (zeige TGFB1 Proteine)/Smad 4 (zeige SMAD4 Proteine) and Dicer (zeige DICER1 Proteine) are essential for the development of prostate cancer mediated by syndecan-1.

  4. The heparanase (zeige HPSE Proteine)/syndecan1 axis in gallbladder carcinoma cells plays an important role in the invasion and metastasis, thus providing a new therapeutic target.

  5. Syndecan-1 acts as a novel tissue biomarker and a modulator of CSC phenotype of triple negative IBC via the IL-6 (zeige IL6 Proteine)/STAT3 (zeige STAT3 Proteine), Notch (zeige NOTCH1 Proteine) and EGFR (zeige EGFR Proteine) signaling pathways, thus emerging as a promising therapeutic target for IBC.

  6. Hepatitis C virus infection downregulates Synd-1 and upregulates Xylt 2 (zeige XYLT2 Proteine) expression, likely contributing to a major glycocalyx reshuffle within days of infection.

  7. Soluble Sdc1 is significantly lower before the clinical onset of preeclampsia, with reduced expression of Sdc1 in the delivered placenta, suggesting a role for glycocalyx disturbance in preeclampsia pathophysiology.

  8. Heparanase (zeige HPSE Proteine) has emerged as a major regulator of cancer by degrading heparan sulfate thereby influencing multiple signaling pathways that control gene expression, syndecan shedding and cell behavior. (Review)

  9. Study provides robust evidence in favor of the additional baseline soluble CD138 prognostic value for OS, in mCRC patients. A simple biological scoring system is proposed including LDH and CD138 binary status values.

  10. it is not appropriate to assume that CD138 expression in urothelial carcinomas is specific for plasmacytoid variants

Mouse (Murine) Syndecan 1 (SDC1) Interaktionspartner

  1. CD138 expression on fully mature Antibody secreting cells (ASCs) provides a selective survival advantage over less mature, newly minted ASCs, by enhancing pro-survival cytokine signaling.

  2. Sdc1 deficiency results in increased susceptibility to colitis-associated tumorigenesis.

  3. MMP7 (zeige MMP7 Proteine) shedding of syndecan-1/CXCL1 (zeige CXCL1 Proteine) complexes functions as a checkpoint that restricts neutrophil activation at sites of epithelial injury.

  4. Data show that heparanase-1 (HPA-1 (zeige HPSE Proteine)) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1) facilitated the release of vascular endothelial growth factor C (VEGF-C (zeige VEGFC Proteine)) from SDC-1/VEGF-C (zeige VEGFC Proteine) complex into the medium of hepatocarcinoma cell.

  5. This study indicates that, while syndecan-1 is important for providing a barrier to acute S. aureus infection in PD, it does not affect peritoneal fibrosis and angiogenesis.

  6. Data suggest a potential mechanism of diabetic enteropathy, which is depending remarkably on syndecan-1 (Sdc1) and -beta-D-glucuronidase (zeige GUSB Proteine) heparanase (HPSE (zeige HPSE Proteine)).

  7. Study showed the expression, distribution and function of syndecan-1 in primary sensory neurons after nerve injury

  8. A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 (zeige ADAM17 Proteine) and promotes lung epithelial tumor cell migration and lung metastasis formation.

  9. The PPARgamma (zeige PPARG Proteine) agonist rosiglitazone rescues Sdc1-/- intradermal adipose tissue, placing PPARgamma (zeige PPARG Proteine) downstream of Sdc1 in triggering adipocyte differentiation

  10. Specific structural motifs in syndecan-1 HS promote Staphylococcus aureus corneal infection by inhibiting neutrophil CRAMP.

Cow (Bovine) Syndecan 1 (SDC1) Interaktionspartner

  1. Heparan sulfate is involved in both centralized and decentralized glycocalyx-mediated mechanotransduction, with GPC1 (zeige GPC1 Proteine) acting as a centralized agent and SDC1 functioning in decentralized mechanotransmission. GPC1 (zeige GPC1 Proteine) mediates NOS3 (zeige NOS3 Proteine) activation.

Syndecan 1 (SDC1) Protein Überblick

Protein Überblick

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Alternative names and synonyms associated with Syndecan 1 (SDC1)

  • Syndecan (Sdc)
  • syndecan 1 (sdc1)
  • syndecan 1 (SDC1)
  • syndecan 1 (Sdc1)
  • syndecan 1-like (LOC100338470)
  • AA408134 Protein
  • AA409076 Protein
  • CD138 Protein
  • CG10497 Protein
  • CT27296 Protein
  • Dmel\\CG10497 Protein
  • dSdc Protein
  • Dsyn Protein
  • HSPG Protein
  • l(2)10608 Protein
  • SDC Protein
  • SDC1 Protein
  • Sstn Protein
  • syd Protein
  • syn Protein
  • syn-1 Protein
  • Syn1 Protein
  • Synd Protein
  • Synd1 Protein
  • SYNDECA Protein
  • Syndecan Protein
  • Syndecan-1 Protein
  • syndecan1 Protein
  • xSyn1 Protein
  • XSyndecan-1 Protein

Bezeichner auf Proteinebene für Syndecan 1 Proteine (SDC1)

CG10497-PA , CG10497-PB , CG10497-PC , CG10497-PD , CG10497-PE , CG10497-PF , CG10497-PG , Sdc-PA , Sdc-PB , Sdc-PC , Sdc-PD , Sdc-PE , Sdc-PF , Sdc-PG , dSyndecan , syndecan , syndecan 1 , CD138 antigen , heparan sulfate proteoglycan fibroblast growth factor receptor , syndecan proteoglycan 1 , syndecan-1 , synstatin , SYND1

GENE ID SPEZIES
37447 Drosophila melanogaster
100038138 Xenopus (Silurana) tropicalis
459052 Pan troglodytes
482986 Canis lupus familiaris
701544 Macaca mulatta
6382 Homo sapiens
20969 Mus musculus
529759 Bos taurus
25216 Rattus norvegicus
100519770 Sus scrofa
421960 Gallus gallus
101836998 Mesocricetus auratus
100689057 Cricetulus griseus
100338470 Oryctolagus cuniculus
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