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After intrastromal scanning of cornea, expression of Ki-67 increases.
injection of a b3-adrenergic receptor (b3-AR) agonist for continuous 5 days increased the number of Ki67-positive brown adipocytes even at Day 1 but not that of SV cells. In addition, the b3-AR antagonist, but not b1-AR antagonist, attenuated the cold exposure-induced increase in the number of Ki67-positive brown adipocytes
Ki67-positive cells are localized near inner enamel epithelium and supra-IEE, the stellate reticulum next to these is Ki67-negative. The IEE and supra-IEE contain intense Ki67-immunoreactivity, outer enamel epithelium lacks proliferative cells in mice.
Whey proteins reduced Ki-67 and 8-OHdG expression in the skin of chronically UVB-irradiated mice.
Both HDAC1 (zeige HDAC1 Proteine) and HDAC2 (zeige HDAC2 Proteine) play crucial roles in the regulation of liver regeneration. The loss of HDAC1 (zeige HDAC1 Proteine)/2 inhibits Ki67 expression and results in defective hepatocyte mitosis and impaired liver regeneration.
Intratumoral FLT uptake level markedly decreased at 6 h and then gradually increased with time.
Late stage cathepsin C (zeige CTSC Proteine), CXCL13 (zeige CXCL13 Proteine) and Ki-67 overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.
The majority of tumours showed strong p16, p21, p27 (zeige CDKN1B Proteine), pRb (zeige PGR Proteine) and cyclin D1 (zeige CCND1 Proteine) staining and little or no p53 (zeige TP53 Proteine) expression. Tumours harbouring dysplasia were significantly more likely to be p53 (zeige TP53 Proteine)-positive and exhibit up-regulated p21 and p27 (zeige CDKN1B Proteine).
Vascular endothelial growth factor (VEGF) expression correlates with p53 and ki-67 expressions in tongue squamous cell carcinoma.
Age-related changes in proliferative markers in labial (zeige LAT2 Proteine) salivary glands: a study of argyrophilic nucleolar organizer regions (AgNORs) and Ki-67
p63 (zeige CKAP4 Proteine) protein is essential for the embryonic development of vibrissae and teeth; while it localizes with K5 in vibrissae, it is not fully colocalized with nuclear Ki67 expression
high Ki67/BCL2 (zeige BCL2 Proteine) index significantly correlated with advanced stage, recurrence, intestinal type, high histologic grade, and lymphatic and perineural invasion in gastric adenocarcinoma
the overexpression of USP7 (zeige USP7 Proteine) might promote cell proliferation by deubiquitinating Ki-67 protein
The results demonstrate that high expression of Ki-67 contributes to radiation resistance and acts a poor prognosis indicator in patients with locally advanced nasopharyngeal carcinoma.
Here the authors show how Ki-67 and RepoMan form mitotic exit phosphatases by recruiting PP1 (zeige PPA1 Proteine), how they distinguish between distinct PP1 (zeige PPA1 Proteine) isoforms and how the assembly of these two holoenzymes are dynamically regulated by Aurora B kinase (zeige AURKB Proteine) during mitosis.
Ki-67 before and after NAC, as well as the change of Ki-67 before and after NAC might be prognostic factors for OS and DFS (zeige FST Proteine) for breast cancer patients.
Ki67 depletion results in the dissociation of both pre-ribosomal RNAs and nucleolar proteins from the perichromosomal layer (PCL (zeige PKD2L1 Proteine)), which indicates that Ki67 is required for the PCL (zeige PKD2L1 Proteine) accumulation of pre-ribosomal RNAs, to which several nucleolar proteins are associated.
Variants near TTN (zeige TTN Proteine) and CCDC8 (zeige CCDC8 Proteine) were associated with KI67 expression, and rs2288563 and rs2562832 in TTN (zeige TTN Proteine) are potential biomarkers for the prediction of clinical outcomes in hepatitis B-related hepatocellular carcinoma patients.
suggest that upregulation of NG2/CSPG4 (zeige MCSP Proteine) rather than changes in CD44 (zeige CD44 Proteine) or Ki-67 expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 (zeige MCSP Proteine) as a potential prognostic marker in glioblastoma
There are considerable differences between the different Ki-67 antibodies in their capacity to detect proliferating tumor cells and to separate low- and high-risk breast cancer patient groups.
Study shows that a Ki67 increase occurs in a significant proportion of patients with entero-pancreatic neuroendocrine neoplasms at time of disease progression, particularly in those with pancreatic origin.
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X.
antigen identified by monoclonal antibody Ki-67
, antigen KI-67-like
, antigen KI-67
, proliferation-related Ki-67 antigen