anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Antikörper

anti-SH3-Domain Kinase Binding Protein 1 Antikörper (SH3KBP1)
Auf finden Sie aktuell 42 SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SH3-Domain Kinase Binding Protein 1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 54 SH3-Domain Kinase Binding Protein 1 Produkte verfügbar.
1200007H22Rik, 1700125L08Rik, 5830464D22Rik, AI447724, CD2BP3, CIN85, GIG10, HSB-1, HSB1, IN85, MIG18, Ruk, Seta

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Weitere Antikörper gegen SH3-Domain Kinase Binding Protein 1 Interaktionspartner

Human SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Interaktionspartner

  1. these data support a role for the novel PP2Ac (zeige PPP2CA Antikörper)-CIN85 complex in supporting integrin-dependent platelet function by dampening the phosphatase activity.

  2. CIN85 promotes recycling of TGF-beta (zeige TGFB1 Antikörper) receptors and thereby positively regulates TGF-beta (zeige TGFB1 Antikörper) signaling.

  3. we demonstrate that SEPT9 (zeige SEPT9 Antikörper) negatively regulates EGFR (zeige EGFR Antikörper) degradation by preventing the association of the ubiquitin ligase Cbl (zeige CBL Antikörper) with CIN85, resulting in reduced EGFR (zeige EGFR Antikörper) ubiquitylation

  4. Results support the model that Cbl (zeige CBL Antikörper)-CIN85-endophilin complex is not required for efficient internalization of EGFR (zeige EGFR Antikörper), a prototype RTK.

  5. Multiple molecular forms of adaptor protein Ruk/CIN85 specifically associate with different subcellular compartments in human breast adenocarcinoma cell line.

  6. LOX (zeige LOX Antikörper)-PP interacts with CIN85 via a novel SH3-binding motif and this association reduces CIN85-promoted invasion by breast cancer cells.

  7. an FRS2beta (zeige FRS3 Antikörper)-CIN85/CD2AP (zeige Cd2ap Antikörper)-Cbl (zeige CBL Antikörper) axis for downregulation of ErbB2 (zeige ERBB2 Antikörper) may regulate ErbB2 (zeige ERBB2 Antikörper) protein levels in physiological and pathological settings

  8. Data show that EGFR (zeige EGFR Antikörper) activation leads to a pronounced src (zeige SRC Antikörper)-mediated tyrosine phosphorylation of CIN85 that subsequently influences EGFR (zeige EGFR Antikörper) ubiquitination.

  9. this study indicates that high levels of Ruk(l)/CIN85 contribute to the conversion of breast adenocarcinoma cells into a more malignant phenotype via modulation of the Src (zeige SRC Antikörper)/Akt (zeige AKT1 Antikörper) pathway.

  10. Data show that CIN85 (c-Cbl interacting protein of 85 kDa) is constitutively associated with c-Cbl (zeige CBL Antikörper), Cbl-b, and B-cell linker (zeige BLNK Antikörper) in B cells.

Mouse (Murine) SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Interaktionspartner

  1. CIN85/RukL is involved in endocytosis of nephrin (zeige NPHS1 Antikörper) in podocytes under diabetic conditions, causing podocyte depletion and promoting proteinuria. CIN85/RukL expression therefore shows potential to be a novel target for antiproteinuric therapy in diabetes.

  2. Dab1 (zeige DAB1 Antikörper) mediated the association of CIN85 with ApoER2 (zeige LRP8 Antikörper) or VLDLR (zeige VLDLR Antikörper) in neurons.

  3. Data suggest that Ser587 Cin85 phosphomimetic mutant protein shows dramatically reduced binding to Dab1 (zeige DAB1 Antikörper) (disabled protein 1) (without affecting binding to CapZ (zeige CAPZA1 Antikörper)).

  4. Sh3kbp1 is SUMOylated by SUMO-1 (zeige SUMO1 Antikörper), -2, and -3 and that SUMOylation is enhanced in the presence of Cd2ap (zeige Cd2ap Antikörper).

  5. the interaction between SHIP-1 (zeige INPP5D Antikörper) and CIN85 might synergistically facilitate the down-regulation of phosphatidylinositol-3,4,5-trisphosphate levels.

  6. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 (zeige BLNK Antikörper) and CIN85 are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  7. a B cell-specific deletion of CIN85 led to impaired T cell-independent type II antibody responses in vivo and diminished IKK-beta (zeige IKBKB Antikörper) activation and cellular responses to B (zeige TDO2 Antikörper) cell receptor cross-linking in vitro

  8. Coexpression of CIN85/Ruk(L) with CD2AP (zeige Cd2ap Antikörper) led to a decreased binding of CIN85/Ruk(L) to nephrin (zeige NPHS1 Antikörper) and podocin, which indicates a functional competition between CD2AP (zeige Cd2ap Antikörper) and CIN85/Ruk(L).

  9. Data indicate an important function of CIN85 (SH3KBP1) in the regulation of dopamine D2 receptor (zeige DRD2 Antikörper) functions and provide a molecular explanation for the hyperactive behaviour of CIN85(Deltaex2) mice.

  10. CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Antigen-Profil

Beschreibung des Gens

This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with SH3-Domain Kinase Binding Protein 1 (SH3KBP1)

  • SH3-domain kinase binding protein 1 (SH3KBP1) Antikörper
  • SH3-domain kinase binding protein 1 (sh3kbp1) Antikörper
  • SH3-domain kinase binding protein 1 (Sh3kbp1) Antikörper
  • 1200007H22Rik Antikörper
  • 1700125L08Rik Antikörper
  • 5830464D22Rik Antikörper
  • AI447724 Antikörper
  • CD2BP3 Antikörper
  • CIN85 Antikörper
  • GIG10 Antikörper
  • HSB-1 Antikörper
  • HSB1 Antikörper
  • IN85 Antikörper
  • MIG18 Antikörper
  • Ruk Antikörper
  • Seta Antikörper

Bezeichner auf Proteinebene für SH3KBP1

SH3-domain kinase binding protein 1 , SH3 domain-containing kinase-binding protein 1-like , CD2-binding protein 3 , SH3 domain-containing kinase-binding protein 1 , Src family kinase-binding protein 1 , c-Cbl-interacting protein , cbl-interacting protein of 85 kDa , human Src family kinase-binding protein 1 , migration-inducing gene 18 , src-related kinase binding protein-1 , SH3-containing, expressed in tumorigenic astrocytes , Sh3 containing, expressed in astrocytes , regulator of ubiquitous kinase , SH3 domain-containing adapter protein , ruk

465527 Pan troglodytes
612797 Canis lupus familiaris
100013895 Monodelphis domestica
100058644 Equus caballus
100151706 Xenopus (Silurana) tropicalis
100357864 Oryctolagus cuniculus
100450340 Pongo abelii
100471577 Ailuropoda melanoleuca
694764 Macaca mulatta
100083478 Ornithorhynchus anatinus
100522530 Sus scrofa
100551401 Meleagris gallopavo
30011 Homo sapiens
58194 Mus musculus
84357 Rattus norvegicus
418608 Gallus gallus
510489 Bos taurus
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