RAB7A, Member RAS Oncogene Family Proteine (RAB7A)

Auf www.antikoerper-online.de finden Sie aktuell 14 RAB7A, Member RAS Oncogene Family (RAB7A) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAB7A, Member RAS Oncogene Family Antikörper (48) und RAB7A, Member RAS Oncogene Family Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 66 RAB7A, Member RAS Oncogene Family Produkte verfügbar.
Synonyme:
ARABIDOPSIS RAB GTPASE HOMOLOG G2, ATRAB7A, ATRABG2, DDBDRAFT_0190210, DDBDRAFT_0191507, DDB_0190210, DDB_0191507, F7D8.20, F7D8_20, LOC100231734, PRO2706, rab-7, Rab7, Rab7a, RAB GTPase homolog 7A, zgc:64058
alle Proteine anzeigen Gen GeneID UniProt
RAB7A 19349 P51150
RAB7A 7879 P51149
RAB7A 29448 P09527

RAB7A, Member RAS Oncogene Family Proteine (RAB7A) nach Spezies

Weitere Proteine zu RAB7A, Member RAS Oncogene Family Interaktionspartnern

Arabidopsis thaliana RAB7A, Member RAS Oncogene Family (RAB7A) Interaktionspartner

  1. MON1/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-mediated Rab7 activation was indispensable for vacuolar trafficking of tapetum degradation-related cysteine proteases.

Zebrafish RAB7A, Member RAS Oncogene Family (RAB7A) Interaktionspartner

  1. Data provide new insight into how disease-associated alterations in Rab7 protein disrupt cellular function in vertebrate sensory neurons. Moreover, findings suggest that defects in axon development may be a previously unrecognized component of Charcot-Marie-Tooth2b disease.

  2. The established transgenic lines ubiquitously express EGFP fusions of Rab5c (zeige Rab5c Proteine) (early endosomes), Rab11a (zeige RAB11A Proteine) (recycling endosomes), and Rab7 (late endosomes) to study localization and dynamics during development.

Mouse (Murine) RAB7A, Member RAS Oncogene Family (RAB7A) Interaktionspartner

  1. WDR91 serves as a Rab7 effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway.

  2. Vps34 (zeige PIK3C3 Proteine) has a previously unknown role in regulating Rab7 activity and late endosomal trafficking.

  3. Rab7 accumulated in GCase (zeige GBA Proteine) deficient cells, supporting the notion that lysosomal recycling is impaired. Since recombinant GCase (zeige GBA Proteine) can reverse ALR (zeige GFER Proteine) impairment, we anticipate that strategies to restore GCase (zeige GBA Proteine) activity in the brains of both sporadic patients with PD and those with GBA1 (zeige GBA Proteine) mutations will improve autophagy lysosomal pathway, preventing the accumulation of a-synuclein and spread of pathology.

  4. The up-regulation of Rab11 (zeige RAB11A Proteine), Rab7, or RILP (zeige RILP Proteine), but not its truncated form RILP (zeige RILP Proteine)-C33 (zeige CD82 Proteine), rescued LAMP2A-defective trafficking in cystinosis, whereas dominant-negative Rab11 (zeige RAB11A Proteine) or Rab7 impaired LAMP2A trafficking.

  5. The inhibition of autophagosome-lysosome fusion induced by SapM is dependent on the interaction between SapM and Rab7.

  6. Prion (zeige PRNP Proteine) infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cells.

  7. photoreceptor outer segments vesicles engulfed through Lyar-dependent pathway were targeted to phagosomes and colocalized with phagosome marker Rab7

  8. B cell Rab7 mediates induction of activation-induced cytidine deaminase (zeige AICDA Proteine) expression and class-switching in T-dependent and T-independent antibody responses.

  9. CREG1 (zeige CREG1 Proteine) deficiency influenced the maturation of lysosomes and reduced the espression of Rab7, which might be involved in CREG1 (zeige CREG1 Proteine)-induced cardiomyocyte autophagy.

  10. Tropheryma whipplei blocks the switch from Rab5 (zeige RAB5A Proteine) to Rab7.

Human RAB7A, Member RAS Oncogene Family (RAB7A) Interaktionspartner

  1. WDR91 serves as a Rab7 (zeige RAB7B Proteine) effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway.

  2. The Vici syndrome protein EPG5 is a Rab7 (zeige RAB7B Proteine) effector that determines the fusion specificity of autophagosomes with late endosomes/lysosomes.

  3. up-regulation of RAB7A reported in Alzheimer's disease, could contribute to the extracellular accumulation of pathological TAU

  4. Rab7 (zeige RAB7B Proteine) accumulated in GCase (zeige GBA Proteine) deficient cells, supporting the notion that lysosomal recycling is impaired. Since recombinant GCase (zeige GBA Proteine) can reverse ALR (zeige GFER Proteine) impairment, we anticipate that strategies to restore GCase (zeige GBA Proteine) activity in the brains of both sporadic patients with PD and those with GBA1 (zeige GBA Proteine) mutations will improve autophagy lysosomal pathway, preventing the accumulation of a-synuclein and spread of pathology.

  5. Rab7a depletion decreases the amount of active Rac1 but not its abundance and reduces the number of cells with vimentin (zeige VIM Proteine) filaments facing the wound, indicating that Rab7a has a role in the orientation of vimentin (zeige VIM Proteine) filaments during migration

  6. The study highlighted the importance of a phosphorylation/dephosphorylation switch in controlling timely Rab7 (zeige RAB7B Proteine) localization and activity on endosomes.

  7. show that the maturation of Mtb (zeige NCAPG2 Proteine)-containing autophagosomes into autolysosomes required recruitment of the late endosome marker RAB7 (zeige RAB7B Proteine), forming the intermediate compartment amphisomes

  8. We validated ANKRD13A as a novel constituent of BCR (zeige BCR Proteine) signalosome and showed that BCR (zeige BCR Proteine)-induced phosphorylation of RAB7A at S72 regulates its association with its effector proteins and with endo-lysosomal compartments.

  9. Hepatitis B virus can regulate its own secretion through an activation of the endo-lysosomal and autophagic pathway mediated by Rab7 (zeige RAB7B Proteine) activation.

  10. provides molecular insights into the essential role of Vps26 (zeige VPS26A Proteine) and Vps35 (zeige vps35 Proteine) in Rab7 (zeige RAB7B Proteine)-mediated recruitment of the core retromer complex

RAB7A, Member RAS Oncogene Family (RAB7A) Protein Überblick

Protein Überblick

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Alternative names and synonyms associated with RAB7A, Member RAS Oncogene Family (RAB7A)

  • RAB7A, member RAS oncogene family (RAB7A)
  • RAB7A, member RAS oncogene family (rab7a)
  • RAB7A, member RAS oncogene family (LOC100231734)
  • rab7A protein (rab7A)
  • RAB GTPase-like protein 7A (RAB7A)
  • Rab GTPase (rab7A)
  • ras-related protein rab-7a (rab7a)
  • dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1)
  • RAB7, member RAS oncogene family (rab7)
  • RAB7, member RAS oncogene family (Rab7)
  • RAB7A, member RAS oncogene family (Rab7a)
  • ARABIDOPSIS RAB GTPASE HOMOLOG G2 Protein
  • ATRAB7A Protein
  • ATRABG2 Protein
  • DDBDRAFT_0190210 Protein
  • DDBDRAFT_0191507 Protein
  • DDB_0190210 Protein
  • DDB_0191507 Protein
  • F7D8.20 Protein
  • F7D8_20 Protein
  • LOC100231734 Protein
  • PRO2706 Protein
  • rab-7 Protein
  • Rab7 Protein
  • Rab7a Protein
  • RAB GTPase homolog 7A Protein
  • zgc:64058 Protein

Bezeichner auf Proteinebene für RAB7A

ras-related protein Rab-7 , ras-related protein Rab-7a , RAB7A, member RAS oncogene family , rab7A protein , ras-related protein rab-7a , RAB7, member RAS oncogene family , dystroglycan , dystrophin-associated glycoprotein 1 , Ras-associated protein RAB7 , GTP-binding protein (rab7) , ras-related protein BRL-RAS , ras-related protein p23

GENE ID SPEZIES
470919 Pan troglodytes
493388 Xenopus (Silurana) tropicalis
707280 Macaca mulatta
100145880 Ovis aries
100231734 Taeniopygia guttata
553895 Lotus japonicus
816724 Arabidopsis thaliana
8616852 Dictyostelium discoideum AX4
100528204 Ictalurus punctatus
281439 Bos taurus
393902 Danio rerio
19349 Mus musculus
7879 Homo sapiens
398880 Xenopus laevis
416016 Gallus gallus
404007 Canis lupus familiaris
29448 Rattus norvegicus
509970 Bos taurus
100008682 Oryctolagus cuniculus
100174486 Pongo abelii
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