anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) Antikörper

anti-Poly (ADP-Ribose) Polymerase 2 Antikörper (PARP2)
Auf finden Sie aktuell 91 Poly (ADP-Ribose) Polymerase 2 (PARP2) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Poly (ADP-Ribose) Polymerase 2 Proteine (7) und Poly (ADP-Ribose) Polymerase 2 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 109 Poly (ADP-Ribose) Polymerase 2 Produkte verfügbar.
Adprt2, Adprtl2, ADPRTL3, ARTD2, Aspartl2, ATPARP1, C78626, cb996, F16D14.16, F16D14_16, pADPRT-2, PARP-2, poly(ADP-ribose) polymerase 1
Alle Antikörper anzeigen Gen GeneID UniProt
PARP2 10038 Q9UGN5
PARP2 290027  
PARP2 11546 O88554

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Am meisten referenzierte anti-Poly (ADP-Ribose) Polymerase 2 Antikörper

  1. Human Polyclonal PARP2 Primary Antibody für EIA, WB - ABIN953995 : Brunyánszki, Hegedus, Szántó, Erdélyi, Kovács, Schreiber, Gergely, Kiss, Szabó, Virág, Bai: Genetic ablation of PARP-1 protects against oxazolone-induced contact hypersensitivity by modulating oxidative stress. in The Journal of investigative dermatology 2010 (PubMed)
    Zeige alle 5 Referenzen für 953995

  2. Human Polyclonal PARP2 Primary Antibody für EIA, WB - ABIN953996 : Toller, Altmeyer, Kohler, Hottiger, Müller: Inhibition of ADP ribosylation prevents and cures helicobacter-induced gastric preneoplasia. in Cancer research 2010 (PubMed)
    Zeige alle 5 Referenzen für 953996

  3. Human Polyclonal PARP2 Primary Antibody für WB - ABIN151360 : Ovadje, Ammar, Guerrero, Arnason, Pandey: Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways. in Oncotarget 2016 (PubMed)

  4. Human Polyclonal PARP2 Primary Antibody für ELISA, WB - ABIN250990 : Kofler, Otsuka, Zhang, Noppens, Grafe, Koh, Dawson, de Murcia, Hurn, Traystman: Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005 (PubMed)

  5. Mouse (Murine) Polyclonal PARP2 Primary Antibody für WB - ABIN656199 : Nicolás, Martínez, Baró, Rodríguez, Baroja-Mazo, Sole, Flores, Ampurdanés, Dantzer, Martin-Caballero, Aparicio, Yelamos: Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice. in Oncogene 2010 (PubMed)

  6. Cow (Bovine) Polyclonal PARP2 Primary Antibody für IF, WB - ABIN2778112 : Malanga, Althaus: Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen Poly (ADP-Ribose) Polymerase 2 Interaktionspartner

Human Poly (ADP-Ribose) Polymerase 2 (PARP2) Interaktionspartner

  1. either PARP1 (zeige PARP1 Antikörper) or PARP2 are sufficient for near-normal XRCC1 (zeige XRCC1 Antikörper) recruitment at oxidative single-strand breaks

  2. Studies indicate that poly(ADP-ribose) polymerase 2 (PARP2) is involved in the differentiation of several cell types, including erythrocytes, T cells and adipocytes.

  3. Findings indicate that Increased poly(ADP-ribose) polymerase-2 (PARP-2) expression and loss of micrRNA miR (zeige MLXIP Antikörper)-149 expression are involved in the pathogenesis of hepatocellular carcinomas (HCC (zeige FAM126A Antikörper)) and are poor prognosis factors in patients with HCC (zeige FAM126A Antikörper).

  4. Data show that E7449 represents a dual Poly(ADP-ribose) Polymerase 1 (zeige PARP1 Antikörper)/2 and tankyrase 1 (zeige TNKS Antikörper)/2 inhibitor which has the advantage of targeting Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling addicted tumors.

  5. The initial affinity between the PARP1 (zeige PARP1 Antikörper), PARP2 and the DNA damaged site appears to influence both the size of the Poly(ADP-Ribose) synthesized and the time of residence of PARylated PARP1 (zeige PARP1 Antikörper) and PARP2 on DNA damages.

  6. Our data suggest for the first time that a SNP in PARP2, rs878156, may together with other genetic variants modulate cancer specific survival in breast cancer patients depending on chemotherapy

  7. Our study differentiates the functions of PARP-2 domains from those of PARP-1 (zeige PARP1 Antikörper), the other major DDR (zeige DDR1 Antikörper)-PARP (zeige COL11A2 Antikörper), and highlights the specialization of the multi-domain architectures of DDR (zeige DDR1 Antikörper)-PARPs.

  8. Interaction of PARP-2 with AP site containing DNA

  9. Identification of ADP-ribosylation sites in PARP2 and the determination of the extent ofpoly(ADP-ribosyl)ated residues in this protein was performed.

  10. Nuclear Smad (zeige SMAD1 Antikörper) function is negatively regulated by PARP-1 (zeige PARP1 Antikörper) that is assisted by PARP-2 and positively regulated by PARG (zeige PARG Antikörper) during the course of TGFB (zeige TGFB1 Antikörper) signaling.

Mouse (Murine) Poly (ADP-Ribose) Polymerase 2 (PARP2) Interaktionspartner

  1. PARP1 (zeige PARP1 Antikörper)/2 inhibitor simmiparib causes growth inhibition in cancer cell- or tissue-derived xenografts in nude mice.

  2. The findings highlight specific non-overlapping functions of PARP1 (zeige PARP1 Antikörper) and PARP2 at H2AX (zeige H2AFX Antikörper)-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 (zeige PARP1 Antikörper) in nonhomologous end-joining-deficient cells.

  3. Data show reduced tumor burden through increased oxidative stress in lung adenocarcinoma cells of PARP-1 (zeige PARP1 Antikörper) and PARP-2 knockout mice.

  4. PARP-2 has an essential role in erythropoiesis by limiting replicative stress in erythroid progenitors.

  5. PARP-1 (zeige PARP1 Antikörper) and -2 play a role in cancer-induced cachexia, thus selective pharmacological inhibition of PARP-1 (zeige PARP1 Antikörper) and -2 may be of interest in clinical settings

  6. the depletion of PARP-2 leads to lower HDL (zeige HSD11B1 Antikörper) levels which represent a risk factor to cardiovascular diseases.

  7. This study represents the first description of a significant role for PARP-2 in neuroinflammation and neurological dysfunction in Experimental autoimmune encephalomyelitis

  8. our data show that PARP-2 can directly regulate base excision repair proteins

  9. Our results show that Parp-2 plays essential roles in the surveillance of genome integrity of stem cell hematopoiesis by orchestrating DNA repair and restraining p53 (zeige TP53 Antikörper)-induced and Puma (zeige BBC3 Antikörper)-mediated apoptosis.

  10. PARP2 activity mobilizes intracellular TRPM2 (zeige TRPM2 Antikörper) channels in a Parp1 (zeige PARP1 Antikörper)-/- background.

Arabidopsis thaliana Poly (ADP-Ribose) Polymerase 2 (PARP2) Interaktionspartner

  1. whilst all isoforms of PARP (zeige PARP1 Antikörper) were localized to the nucleus they are also present in non-nuclear locations with parp1 and parp3 (zeige PARP3 Antikörper) also localised in the cytosol, and parp2 also present in the mitochondria

  2. Studies indicate that a massive and rapid accumulation of a massive and rapid accumulation poly(ADP-ribose) polymerases AtPARP1 and AtPARP2 transcripts was observed upon treatment with ionizing radiation and reactive oxigen species (ROS (zeige ROS1 Antikörper)).

  3. PARP (zeige PARP1 Antikörper) isoforms play a minor role in telomere length maintenance in Arabidopsis.

  4. Evidence suggests a link between the glutathione pool and PARP (zeige PARP1 Antikörper) expression and activity that is perhaps related to the distribution of intracellular glutathione between the cytoplasm and the nucleus. [PARP1]

  5. in PARP2-deficient Arabidopsis plants, the observed abiotic stress resistance can also be explained by alterations in abscisic acid levels that facilitate the induction of a wide set of defense-related genes

Poly (ADP-Ribose) Polymerase 2 (PARP2) Antigen-Profil

Beschreibung des Gens

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

Alternative names and synonyms associated with Poly (ADP-Ribose) Polymerase 2 (PARP2)

  • poly (ADP-ribose) polymerase family, member 2 (parp2) Antikörper
  • poly (ADP-ribose) polymerase 2 (parp2) Antikörper
  • poly (ADP-ribose) polymerase 2 (PARP2) Antikörper
  • poly (ADP-ribose) polymerase 2 (Parp2) Antikörper
  • poly (ADP-ribose) polymerase family, member 2 (Parp2) Antikörper
  • poly [ADP-ribose] polymerase 2 (PARP1) Antikörper
  • Adprt2 Antikörper
  • Adprtl2 Antikörper
  • ADPRTL3 Antikörper
  • ARTD2 Antikörper
  • Aspartl2 Antikörper
  • ATPARP1 Antikörper
  • C78626 Antikörper
  • cb996 Antikörper
  • F16D14.16 Antikörper
  • F16D14_16 Antikörper
  • pADPRT-2 Antikörper
  • PARP-2 Antikörper
  • poly(ADP-ribose) polymerase 1 Antikörper

Bezeichner auf Proteinebene für PARP2

poly (ADP-ribose) polymerase family, member 2 , ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2 , ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2 , poly [ADP-ribose] polymerase 2 , poly (ADP-ribose) polymerase 2 , poly [ADP-ribose] polymerase 2-like , ADP-ribosyltransferase diphtheria toxin-like 2 , ADPRT-2 , NAD(+) ADP-ribosyltransferase 2 , hPARP-2 , poly (ADP-ribosyl) transferase-like 2 , poly(ADP-ribose) synthetase , poly[ADP-ribose] synthase 2 , poly[ADP-ribose] synthetase 2 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 2 , mPARP-2 , pADPRT-2

386773 Danio rerio
446370 Xenopus laevis
465197 Pan troglodytes
701955 Macaca mulatta
100452137 Pongo abelii
10038 Homo sapiens
475392 Canis lupus familiaris
505828 Bos taurus
290027 Rattus norvegicus
11546 Mus musculus
817690 Arabidopsis thaliana
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