anti-MutY Homolog (E. Coli) (MUTYH) Antikörper

Bezeichnung:
anti-MutY Homolog (E. Coli) Antikörper (MUTYH)
Auf www.antikoerper-online.de finden Sie aktuell 99 MutY Homolog (E. Coli) (MUTYH) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MutY Homolog (E. Coli) Kits (9) und MutY Homolog (E. Coli) Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 123 MutY Homolog (E. Coli) Produkte verfügbar.
Synonyme:
5730495A01Rik, CYP2C, MGC145569, MUTYH, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, Myh

Meistgesuchte Reaktivitäten zu anti-MutY Homolog (E. Coli) (MUTYH) Antikörper

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Am meisten referenzierte anti-MutY Homolog (E. Coli) Antikörper

  1. Bacteria Polyclonal MUTYH Primary Antibody für ICC, IF - ABIN153079 : Bonde, Gao, Chen, Miyashita, Montgomery, Harmon, Wei: Duodenal reflux leads to down regulation of DNA mismatch repair pathway in an animal model of esophageal cancer. in The Annals of thoracic surgery 2007 (PubMed)
    Zeige alle 8 Referenzen für 153079

  2. Human Monoclonal MUTYH Primary Antibody für IP, RNAi - ABIN561883 : van der Post, Kets, Ligtenberg, van Krieken, Hoogerbrugge: Immunohistochemistry is not an accurate first step towards the molecular diagnosis of MUTYH-associated polyposis. in Virchows Archiv : an international journal of pathology 2008 (PubMed)
    Zeige alle 7 Referenzen für 561883

  3. Human Polyclonal MUTYH Primary Antibody für EIA, FACS - ABIN953552 : Kim, Cho, Park, Kim, Nam, Lee, Yoo, Lee, Park: Genetic alterations of the MYH gene in gastric cancer. in Oncogene 2004 (PubMed)
    Zeige alle 3 Referenzen für 953552

  4. Human Polyclonal MUTYH Primary Antibody für ELISA, WB - ABIN334441 : Slupska, Baikalov, Luther, Chiang, Wei, Miller: Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage. in Journal of bacteriology 1996 (PubMed)

  5. Human Polyclonal MUTYH Primary Antibody für IF, ELISA - ABIN1534474 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

Weitere Antikörper gegen MutY Homolog (E. Coli) Interaktionspartner

Horse (Equine) MutY Homolog (E. Coli) (MUTYH) Interaktionspartner

  1. qPCR analysis of cDNA from the cerebella of affected and unaffected horses suggested that MUTYH expression is down-regulated in affected horses.

Human MutY Homolog (E. Coli) (MUTYH) Interaktionspartner

  1. These results suggested that reduced MUTYH expression is associated with somatic mutation loads via a reduction in DNA repair capacity in prostate adenocarcinoma.

  2. MTH1 (zeige NUDT1 Antikörper) together with MYH plays an important role in protection against mutations induced by modified dNTPs during chronic oxidative stress.

  3. Reduced MUTYH, MTH1 (zeige NUDT1 Antikörper), and OGG1 (zeige OGG1 Antikörper) expression and TP53 (zeige TP53 Antikörper) mutations occur in diffuse-type adenocarcinoma of gastric cardia.

  4. Authors identified 266 probands (91% Caucasians) with a MUTYH mutation (41 biallelic and 225 monoallelic) from the Colon Cancer Family Registry. Mutation status, sex, age and histories of cancer from their 1,903 first- and 3,255 second-degree relatives were analyzed using modified segregation analysis conditioned on the ascertainment criteria.

  5. A high heterogeneity of MUTYH variants and a high rate of variants of unknown significance were identified in a cohort of Italian patients with suspected MUTYH-associated polyposis. Genotype-phenotype analysis suggests that the p.Glu480del variant is associated with a severe phenotype.

  6. Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.

  7. report of the results of functional evaluation of nine missense-type MUTYH variant proteins in the Japanese population; findingssuggest that p.N238S and p.R247G are likely to be pathogenic alleles for MUTYH-associated polyposis

  8. Case Report: MUTYH-associated polyposis with cutaneous sebaceous lesions.

  9. The IVS10-2A>G MUTYH heterozygote variant might add to the risk of developing germline APC (zeige APC Antikörper) mutation negative colorectal adenomatous polyposis in Japanese patients.

  10. MutY homolog Y165C and G382D mutations are not associated with cholangiocarinoma.

Mouse (Murine) MutY Homolog (E. Coli) (MUTYH) Interaktionspartner

  1. Ogg1 (zeige OGG1 Antikörper) and Mutyh regulate hippocampal gene expression related to cognition and behavior, suggesting a role for the glycosylases in regulating adaptive behavior.

  2. MUTYH loss is associated with an increase in inflammation associated colorectal cancer risk, which involves immunosuppression and altered inflammatory response.

  3. Results show that MYH is a vital DNA repair enzyme (zeige LIG4 Antikörper) that protects cells from oxidative DNA damage and is critical for a proper cellular response to DNA damage.

  4. a 5-methylcytosine glycosylase activity for the murine DNA base excision repair enzyme Myh is described and shown that it is critically involved in remodeling the IL-2 (zeige IL2 Antikörper) Promoter for transcription.

  5. Data indicate that maternal folate depletion during pregnancy and high-fat feeding from weaning altered gene expression of Ogg1 (zeige OGG1 Antikörper), Neil1 (zeige NEIL1 Antikörper), Mutyh and Xrcc1 (zeige XRCC1 Antikörper) in the brain of adult offspring.

  6. The action of MUTYH, which initiates excision repair of adenine opposite 8-oxoG, triggers neurodegeneration in mice.

  7. OGG1 (zeige OGG1 Antikörper) and MYH appear to be dispensable for antimutator function in mitochondria.

  8. Mutyh plays a major role in maintaining intestinal integrity by affecting the inflammatory response.

  9. Aim of this study was to characterize the biological effects, in a mammalian cell background, of human MUTYH mutations identified in MUTYH-associated polyposis patients

  10. Replication-associated repair of adenine:8-oxoguanine mispairs by MYH

MutY Homolog (E. Coli) (MUTYH) Antigen-Profil

Beschreibung des Gens

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MutY Homolog (E. Coli) (MUTYH)

  • mutY homolog (E. coli) (MUTYH) Antikörper
  • mutY homolog (MUTYH) Antikörper
  • mutY homolog (mutyh) Antikörper
  • mutY homolog (LOC100373318) Antikörper
  • mutY homolog (E. coli) (Mutyh) Antikörper
  • 5730495A01Rik Antikörper
  • CYP2C Antikörper
  • MGC145569 Antikörper
  • MUTYH Antikörper
  • Mutyha Antikörper
  • Mutyhalpha Antikörper
  • Mutyhb Antikörper
  • Mutyhbeta Antikörper
  • Mutyhc Antikörper
  • Myh Antikörper

Bezeichner auf Proteinebene für MUTYH

mutY homolog (E. coli) , A/G-specific adenine DNA glycosylase , A/G-specific adenine DNA glycosylase-like , mutY homolog , adenine-DNA glycosylase , mMYH , mutY homolog alpha , the full-length form type A, 5' region , rMYH

GENE ID SPEZIES
424594 Gallus gallus
456539 Pan troglodytes
482515 Canis lupus familiaris
513051 Bos taurus
100052596 Equus caballus
100397524 Callithrix jacchus
100465330 Ailuropoda melanoleuca
100513867 Sus scrofa
705651 Macaca mulatta
780292 Xenopus (Silurana) tropicalis
100373318 Saccoglossus kowalevskii
4595 Homo sapiens
70603 Mus musculus
170841 Rattus norvegicus
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