TNFSF4 Proteine (TNFSF4)

Tumor Necrosis Factor (Ligand) Superfamily, Member 4 Proteine (TNFSF4)
Auf finden Sie aktuell 28 Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFSF4 Antikörper (237) und TNFSF4 Kits (26) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 304 TNFSF4 Produkte verfügbar.
Ath-1, Ath1, CD134L, CD252, gp34, OX-40L, OX4OL, Ox40l, TNFRSF4, TNFSF4, TXGP1, Txgp1l
alle Proteine anzeigen Gen GeneID UniProt
TNFSF4 7292 P23510
TNFSF4 22164 P43488
Ratte TNFSF4 TNFSF4 89814 Q9Z2P3

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Am meisten referenzierte TNFSF4 Proteine

  1. Human TNFSF4 Protein expressed in HEK-293 - ABIN2666855 : Aspord, Leccia, Charles, Plumas: Plasmacytoid dendritic cells support melanoma progression by promoting Th2 and regulatory immunity through OX40L and ICOSL. in Cancer immunology research 2014 (PubMed)
    Zeige alle 5 Referenzen für 2666855

  2. Cynomolgus TNFSF4 Protein expressed in Human Cells - ABIN2009818 : Weiguang, Dalin, Lidan, Yonggang, Shuang, Yanhong, Fengyan, Zhenkun, Da, Dianjun: Association of OX40L polymorphisms with sporadic breast cancer in northeast Chinese Han population. in PLoS ONE 2012 (PubMed)

  3. Human TNFSF4 Protein expressed in HEK-293 Cells - ABIN1344408 : Mestas, Crampton, Hori, Hughes: Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA. in International immunology 2005 (PubMed)

Weitere Proteine zu TNFSF4 Interaktionspartnern

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) Interaktionspartner

  1. OX40 (zeige TNFRSF4 Proteine) and OX40L formed a functional complex, which may facilitate signal transduction from OX40L to OX40 (zeige TNFRSF4 Proteine) and contribute to the pathogenesis of Grave's disease.

  2. The polymorphisms of the TNFSF4 gene may contribute to the susceptibility to pathogenesis of early-Onset Autoimmune Thyroid Diseases and Hypothyroidism of Hashimoto's Thyroiditis.

  3. the SNPs in TNFSF4 and FAM167A-BLK may be involved in asthma and allergic rhinitis gene risk in the Han Chinese cohort.

  4. Given the discovery cohort, functional data, and importance of TNFSF4 in infection clearance, TNFSF4C may associate with outcomes and warrants future studies.

  5. Review/Meta-analysis: TNFSF4 (rs3850641) polymorphisms is not associated with coronary heart disease risk.

  6. Study showed that the A allele of the rs7518045 and haplotype rs3861950C-rs17346501C-rs7518045A-rs1234313G in the TNFSF4 gene were associated with decreased risk for myocardial infarction in a Chinese Han population.

  7. Data indicate that soluble OX40 (zeige TNFRSF4 Proteine) and sOX40L plasma levels are increased in early rheumatoid arthritis patients.

  8. Report role of TNFSF4 genetic variants in confering risk of systemic lupus erythematosus in Chinese population.

  9. There were no significant associations between rs1234313, rs1234314 and rs17568 and atherosclerotic cerebral infarction risk in a Han Chinese population.

  10. Blocking of the interaction between OX40 and OX40L in vitro inhibited production of Thl and Th2 type cytokines in acute renal allograft rejection.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) Interaktionspartner

  1. The OX40L expression is induced on the bronchiolar progenitors for the antiviral immunity during the infectious process. However, these defense-like host responses lead to more extensive infection with the influenza virus owing to the induced OX40L with alpha-2,6 sialic acid modification, which augments the interaction with the viral hemagglutinin (zeige HA Proteine).

  2. bone marrow-derived mast cell (BMMC)-exosomes facilitated the differentiation of naive CD4 (zeige CD4 Proteine)+ T cells to Th2 cells by ligation of OX40L and OX40 (zeige TNFRSF4 Proteine) between BMMC-exosomes and CD4 (zeige CD4 Proteine)+ T cells and represents a novel mechanism of cell-to-cell communication

  3. Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin (zeige TSLP Proteine), and IL-33 (zeige IL33 Proteine)

  4. Anti-OX40L mAb could prolong secondary heart allograft survival based on CD40 (zeige CD40 Proteine)/CD40L (zeige CD40LG Proteine) and LFA-1 (zeige ITGAL Proteine)/ICAM-1 (zeige ICAM1 Proteine) blockade.

  5. intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4 (zeige CD4 Proteine)(+) Th cell-intrinsic IL-4 (zeige IL4 Proteine) program that is controlled by DC OX40L, and not by NKT (zeige CTSL1 Proteine), gammadelta T, or ILC (zeige CCL27 Proteine) cells.

  6. a critical role of OX40L presented by the activated basophils to initiate Th2 responses in an allergic asthma model, implicating OX40 (zeige TNFRSF4 Proteine)-OX40L signaling as a potential therapeutic target in the treatment of allergic airway inflammation.

  7. The majority of transferred CD40L (zeige CD40LG Proteine)(-/-) T cells in Rag-1 (zeige RAG1 Proteine)(-/-) B6 mice were differentiated to CD44 (zeige CD44 Proteine)(high).

  8. OX40 (zeige TNFRSF4 Proteine)-OX40L interaction regulates the expression of NFATc1 (zeige NFATC1 Proteine), which may play a critical role in atherosclerotic plaque formation, and may therefore have implications with pathophysiology of atherosclerosis.

  9. The need for additional immune suppression in the intestine reflects commensal microbe-driven T-cell activation through the accessory costimulation molecules ICOSL (zeige ICOSLG Proteine) and OX40L in B7 deprived mice.

  10. we identify a previously unknown role for OX40L in steady-state bone homeostasis

TNFSF4 Protein Überblick

Protein Überblick

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.

Alternative names and synonyms associated with TNFSF4

  • tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4)
  • tumor necrosis factor (ligand) superfamily, member 4 (Tnfsf4)
  • Ath-1 Protein
  • Ath1 Protein
  • CD134L Protein
  • CD252 Protein
  • gp34 Protein
  • OX-40L Protein
  • OX4OL Protein
  • Ox40l Protein
  • TNFRSF4 Protein
  • TNFSF4 Protein
  • TXGP1 Protein
  • Txgp1l Protein

Bezeichner auf Proteinebene für TNFSF4

tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) , tumor necrosis factor (ligand) superfamily, member 4 , tumor necrosis factor ligand superfamily member 4 , CD134(OX40)-ligand , OX40L protein , CD134 ligand , OX40 antigen ligand , OX40L , TAX transcriptionally-activated glycoprotein 1 , glycoprotein Gp34 , tax-transcriptionally activated glycoprotein 1 (34kD) , OX40 ligand , atherosclerosis 1 , tax-transcriptionally activated glycoprotein 1 ligand

469586 Pan troglodytes
490339 Canis lupus familiaris
539800 Bos taurus
706255 Macaca mulatta
790947 Felis catus
574053 Sus scrofa
7292 Homo sapiens
22164 Mus musculus
89814 Rattus norvegicus
100008595 Oryctolagus cuniculus
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