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ICAM-1 Proteine (ICAM1)

Intercellular Adhesion Molecule 1 Proteine (ICAM1)
Auf finden Sie aktuell 65 Intercellular Adhesion Molecule 1 (ICAM1) Proteine von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ICAM-1 Antikörper (940) und ICAM-1 Kits (143) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1172 ICAM-1 Produkte verfügbar.
BB2, CD54, ICAM, ICAM-1, ICAM1, Ly-47, MALA-2, P3.58
alle Proteine anzeigen Gen GeneID UniProt
ICAM1 3383 P05362
ICAM1 15894 P13597
ICAM1 25464 Q00238

Weitere Synonyme anzeigen

ICAM-1 Proteine (ICAM1) nach Spezies

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Am meisten referenzierte ICAM-1 Proteine

  1. Mouse (Murine) ICAM-1 Protein expressed in CHO Cells - ABIN2666825 : Greve, Davis, Meyer, Forte, Yost, Marlor, Kamarck, McClelland: The major human rhinovirus receptor is ICAM-1. in Cell 1989 (PubMed)
    Zeige alle 8 Referenzen für ABIN2666825

  2. Human ICAM-1 Protein expressed in CHO Cells - ABIN2666823 : Rothlein, Dustin, Marlin, Springer: A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. in Journal of immunology (Baltimore, Md. : 1950) 1986 (PubMed)
    Zeige alle 8 Referenzen für ABIN2666823

  3. Human ICAM-1 Protein expressed in Escherichia coli (E. coli) - ABIN1047208 : Staunton, Marlin, Stratowa, Dustin, Springer: Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. in Cell 1988 (PubMed)
    Zeige alle 3 Referenzen für ABIN1047208

  4. Human ICAM-1 Protein expressed in Human Cells - ABIN2002637 : Bhalla, Chugh, Mehrotra, Rathore, Tousif, Prakash Dwivedi, Prakash, Kumar Samuchiwal, Kumar, Kumar Singh, Ghanwat, Kumar, Das, Mohmmed, Malhotra, Ranganathan: Host ICAMs play a role in cell invasion by Mycobacterium tuberculosis and Plasmodium falciparum. in Nature communications 2015 (PubMed)

Weitere Proteine zu ICAM-1 Interaktionspartnern

Human Intercellular Adhesion Molecule 1 (ICAM1) Interaktionspartner

  1. KDM7A mediates TNF-alpha (zeige TNF Proteine)-induced ICAM1 protein upregulation.

  2. Genetic inactivation and blockade studies revealed that homophilic interactions between intercellular adhesion molecule 1 (ICAM-1) expressed on tumor cells and MSCs, respectively, regulate the competition between tumor cells and HSPCs for binding to MSCs. Moreover, tumor cell-secreted soluble ICAM-1(sICAM-1) also impaired HSPC (zeige PSMA7 Proteine) adhesion via blocking CD18 (zeige ITGB2 Proteine)-ICAM-1 binding between HSPCs and MSCs

  3. Importantly, while HIV-1 Vpu-mediated downregulation of ICAM-3 (zeige ICAM3 Proteine) has a limited effect on the conjugation of natural killer cells to HIV-1-infected CD4 (zeige CD4 Proteine)(+) T cells, downregulation of ICAM-1 by Vpu results in a reduced ability of natural killer cells to bind and kill infected T cells.

  4. CD54 was upregulated and enriched specifically at the contact area between pro-inflammatory classically activated macrophages and Mesenchymal Stromal Cells (MSCs). Moreover, the specific interaction induced calcium signaling and increased the immunosuppressive capacities of MSCs dependent on CD54 mediation.

  5. Lipopolysaccharide induces p42/p44 (zeige PSMC6 Proteine) MAPK (zeige MAPK3 Proteine) activation mediated through the TLR4 (zeige TLR4 Proteine)/MyD88 (zeige MYD88 Proteine)/TRAF6 (zeige TRAF6 Proteine)/c-Src (zeige SRC Proteine)/NADPH oxidase (zeige NOX1 Proteine)/ROS (zeige ROS1 Proteine)/EGFR (zeige EGFR Proteine), PDGFR (zeige PDGFRB Proteine)/PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway, which in turn initiates the activation of NF-kappaB (zeige NFKB1 Proteine) and ultimately induces ICAM-1 expression in human pulmonary alveolar epithelial cells.

  6. Our results suggest that an impairment in adhesion exists in vitiligo (zeige MITF Proteine) skin, which is supported by the diminished immunohistochemical expression of laminin, beta1 integrin, ICAM-1 and VCAM-1 (zeige VCAM1 Proteine).

  7. Soluble intercellular adhesion molecule-1 levels in drained dialysate are associated with peritoneal injury in patients on peritoneal dialysis. These results suggest that soluble intercellular adhesion molecule-1 could be a novel biomarker of peritoneal injury in patients on peritoneal dialysis.

  8. This study suggests a possible association between the ICAM-1 polymorphism and the disease severity.

  9. Both ICAM-1 and ICAM-2 (zeige ICAM2 Proteine) levels in plasma were markedly increased in Ankylosing Spondylitis Chinese patients compared to controls.

  10. This study investigated the possibility of K469E (rs5498) and G241R (rs1799969) polymorphisms, in ICAM-1 gene, and G634C (rs1800796), in IL-6 (zeige IL6 Proteine) gene, being associated with the occurrence of endometriosis . All individuals were wild homozygotes for G241R polymorphism. This study suggests that polymorphisms K469E, G241R, and G634C are not associated with increased susceptibility to endometriosis

Mouse (Murine) Intercellular Adhesion Molecule 1 (ICAM1) Interaktionspartner

  1. Data suggest CKIP1 (casein kinase 2 interacting protein-1) plays role in resistance to oxidative stress in glomerular mesangial cells in development of diabetic nephropathy; mechanisms appear to include down-regulation of expression of ICAM1 (intercellular adhesion molecule-1) and fibronectin (zeige FN1 Proteine) plus activation of Nrf2 (zeige NFE2L2 Proteine)/ARE (nuclear factor E2-related factor 2/antioxidant response element) antioxidative stress pathway.

  2. ICAM1 regulates pathological cardiac remodeling by mediating proinflammatory leukocyte infiltration in the left ventricle and cardiac fibrosis and dysfunction.

  3. Its antiatherogenic impact might be associated with a suppressed adhesion to the endothelium due to down-regulation of endothelial ICAM-1 expression.

  4. Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA (zeige PCNA Proteine) and up-regulation of ICAM-1 in tumor tissue of tumor-bearing mice, thereby achieving its anti-tumor effect.

  5. our results further highlight the pleiotropic role of ICAM-1 in T-cell-dependent immune responses, with a major role in Treg cell development and suppressive function.

  6. the present results shed light on regulation of expression and function of ICAM-1 on neutrophils and identify it as an additional regulator of neutrophil effector responses in host defense.

  7. we identified intracellular adhesion molecule (ICAM)-1, through fibrinogen binding, as a previously unreported mediator of platelet-monocyte interactions

  8. miR (zeige MLXIP Proteine)-222 was transported into recipient endothelial cells by endothelial microparticles and functionally regulated expression of its target protein ICAM-1 in vitro and in vivo.

  9. Timely blockade of ICAM-1.LFA-1 (zeige ITGAL Proteine) interaction prevents disease onset in a mouse model of emphysema.

  10. MRTF-A/B depletion results in an increase in the cell surface expression of ICAM-1 and interactions between HAoECs and leukocytes

Cow (Bovine) Intercellular Adhesion Molecule 1 (ICAM1) Interaktionspartner

  1. ADMA has potent adverse effects on cell proliferation, intracellular ROS (zeige ROS1 Proteine) generation, cell permeability, levels of ICAM-1, and the tight-junction protein occludin (zeige OCLN Proteine)

Pig (Porcine) Intercellular Adhesion Molecule 1 (ICAM1) Interaktionspartner

  1. Neutrophil lung infiltrations in porcine reproductive and respiratory syndrome virus infection infected animals is both ICAM-1 dependent and independent.

  2. Chitosan oligosaccharides downregulate the expression of E-selectin (zeige SELE Proteine) and ICAM-1 by inhibiting the phosphorylation of Mitogen-Activated Protein Kinases and the activation of NF-kappaB (zeige NFKB1 Proteine) in lipopolysaccharides treated porcine iliac artery endothelial cells.

  3. Data show that all five molecules, BNP, ICAM-1, TNF-alpha (zeige TNF Proteine), VCAM-1 (zeige VCAM1 Proteine) and IL-6 (zeige IL6 Proteine), quickly and reliably signaled adverse interactions.

  4. Altered shear stress stimulates upregulation of endothelial VCAM-1 (zeige VCAM1 Proteine) and ICAM-1 in a BMP-4 (zeige BMP4 Proteine)- and TGF-beta1 (zeige TGFB1 Proteine)-dependent pathway.

Rabbit Intercellular Adhesion Molecule 1 (ICAM1) Interaktionspartner

  1. ICAM1 and IL10 (zeige IL10 Proteine) were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 (zeige JUN Proteine) may be responsible for this upregulation.

  2. Hepatocellular glycogen (zeige GYS1 Proteine) decreases the expression of ICAM-1 mRNA of hepatic stellate cells.

ICAM-1 (ICAM1) Protein Überblick

Protein Überblick

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Alternative names and synonyms associated with ICAM-1 (ICAM1)

  • intercellular adhesion molecule 1 (ICAM1)
  • intercellular adhesion molecule 1 (Icam1)
  • intercellular adhesion molecule-1 (ICAM-1)
  • intercellular adhesion molecule-1 precursor (ICAM-1)
  • BB2 Protein
  • CD54 Protein
  • ICAM Protein
  • ICAM-1 Protein
  • ICAM1 Protein
  • Ly-47 Protein
  • MALA-2 Protein
  • P3.58 Protein

Bezeichner auf Proteinebene für ICAM1

intercellular adhesion molecule 1 , intercellular adhesion molecule 1-like , ICAM-1 , cell surface glycoprotein P3.58 , intercellular adhesion molecule 1 (CD54), human rhinovirus receptor , major group rhinovirus receptor , myD10 , leukocyte adhesion molecule

100437727 Pongo abelii
100593834 Nomascus leucogenys
3383 Homo sapiens
15894 Mus musculus
25464 Rattus norvegicus
403975 Canis lupus familiaris
100717967 Cavia porcellus
281839 Bos taurus
100980120 Pan paniscus
450196 Pan troglodytes
712280 Macaca mulatta
396750 Sus scrofa
100009455 Oryctolagus cuniculus
443045 Ovis aries
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