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anti-Human CX3CR1 Antikörper:
anti-Mouse (Murine) CX3CR1 Antikörper:
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Mouse (Murine) Polyclonal CX3CR1 Primary Antibody für FACS - ABIN4897824
Wattananit, Tornero, Graubardt, Memanishvili, Monni, Tatarishvili, Miskinyte, Ge, Ahlenius, Lindvall, Schwartz, Kokaia: Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2016
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Mouse (Murine) Polyclonal CX3CR1 Primary Antibody für FACS - ABIN4897825
van Nieuwenhuijze, Coghill, Gray, Prato, Metcalf, Alexander, Wicks: Transgenic expression of GM-CSF in T cells causes disseminated histiocytosis. in The American journal of pathology 2013
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Human Polyclonal CX3CR1 Primary Antibody für ELISA, FACS - ABIN4301023
Aoyama, Inokuchi, Brenner, Seki: CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. in Hepatology (Baltimore, Md.) 2010
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Human Polyclonal CX3CR1 Primary Antibody für CyTOF, FACS - ABIN4900502
Fan, Xiong, Zhang, Yan, Jian, Xu, Zhao: MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. in Journal of the American Heart Association 2016
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Human Polyclonal CX3CR1 Primary Antibody für FACS, WB - ABIN2473127
Imai, Hieshima, Haskell, Baba, Nagira, Nishimura, Kakizaki, Takagi, Nomiyama, Schall, Yoshie: Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. in Cell 1997
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Human Polyclonal CX3CR1 Primary Antibody für WB - ABIN411456
Kim, Rooper, Xie, Kajdacsy-Balla, Barbolina: Fractalkine receptor CX(3)CR1 is expressed in epithelial ovarian carcinoma cells and required for motility and adhesion to peritoneal mesothelial cells. in Molecular cancer research : MCR 2012
Human Monoclonal CX3CR1 Primary Antibody für ELISA, WB - ABIN560540
Nevo, Sagi-Assif, Meshel, Ben-Baruch, Jöhrer, Greil, Trejo, Kharenko, Feinmesser, Yron, Witz: The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells. in Cancer letters 2008
Human Polyclonal CX3CR1 Primary Antibody für FACS, IHC - ABIN110594
Held-Feindt, Hattermann, Mueerkoester, Wedderkopp, Knerlich-Lukoschus, Ungefroren, Mehdorn, Mentlein: CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs). in Experimental cell research 2010
Mouse (Murine) Polyclonal CX3CR1 Primary Antibody für FACS - ABIN4897822
Nie, Li, Hu, Jin, Yu, Cai, Shao, Shen, Yi, Xiao, Shen, He: Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors. in PLoS ONE 2014
Mouse (Murine) Polyclonal CX3CR1 Primary Antibody für FACS - ABIN4897821
Arieta Kuksin, Gonzalez-Perez, Minter: CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. in Blood 2015
CX3CR1 genetic variants were not associated with risk of atherosclerotic coronary heart disease and glucometabolic traits in European ancestry cohort. In a South Asian cohort, identified CX3CR1 SNP associated with myocardial infarction and type II diabetes mellitus.
FKN and CX3CR1 expression was significantly increased in pancreatic ductal adenocarcinoma (PDAC) tissues, especially in the metastatic samples, and was highly-correlated with severity of PDAC. Ectopic expression of FKN promoted the proliferation and migration of PDAC, while knockdown of CX3CR1 reversed the function of FKN.
CX3CL1 (zeige CX3CL1 Antikörper) is upregulated in both human and murine tumors following VEGF (zeige VEGFA Antikörper) signaling blockade, resulting in recruitment of CX3CR1+Ly6Clo monocytes into the tumor
The fractalkine (zeige CX3CL1 Antikörper) functions on the activation of the AKT (zeige AKT1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper)/p65 (zeige GORASP1 Antikörper) signalling cascade and regulation of the antiapoptosis process in pancreatic cancer cells.
High expression of CX3CR1 correlates with significantly shorter survival, specifically in post-menopausal patients with advanced and terminal stages of the disease. Taken together, this support a key regulatory role for the fractalkine (zeige CX3CL1 Antikörper) axis in advanced and relapsed peritoneal metastasis in epithelial ovarian carcinoma.
V249I genotype of the fractalkine receptor showed a protector role in patients with type 2 diabetes. The T280M genotype is associated with increased carotid intima-media thickness in Mexican individuals with or without type 2 diabetes
CX3CR1 genetic variation sows a possible association with hypertension, diabetes mellitus and atherosclerosis comorbidities in patients treated with hemodialysis.
this study shows that the expression of CX3CR1 on tonsillar CD8-positive cells is higher in IgA nephropathy patients
Low CCRL1 expression is associated with hepatocellular carcinoma.
Recent works show that, in allergic diseases, there is an increased expression of fractalkine/CX3CL1 (zeige CX3CL1 Antikörper) and its unique receptor CX3CR1 and that this chemokine (zeige CCL1 Antikörper) does not act as chemoattractant. In allergic asthma, CX3CR1 expression regulates Th2 and Th1 (zeige TH1L Antikörper) cell survival in the inflammatory lung, while, in atopic dermatitis, it regulate Th2 and Th1 (zeige TH1L Antikörper) cell retention into the inflammatory site. [review]
our study demonstrates that macrophages expressing a functional CX3CR1 receptor have an important and non-redundant role in controlling the abnormal intestinal inflammation that may lead to tissue damage.
These results highlight the importance of fractalkine (zeige CX3CL1 Antikörper)-CX3CR1 interaction in recruitment of macrophages into the brown adipose tissue of obese mice.
Results indicate that deletion of CX3CR1 from microglia under resting conditions modifies brain areas with elevated cellular turnover independent of CX3CL1 (zeige CX3CL1 Antikörper).
The CX3CL1 (zeige CX3CL1 Antikörper)/CX3CR1 system is essential for restricting coxsackievirus B3-induced myocarditis.
Results establish an essential role for the receptor CX3CR1 in gut (zeige GUSB Antikörper) macrophages in resolving inflammation in the intestine, where it helps protects against colitis-associated cancer by regulating HMOX-1 (zeige HMOX1 Antikörper) expression.
CX3CR1 significantly contributes to changes in microglia morphology in the proximal peri (zeige POSTN Antikörper)-infarct area following transient occlusion of the middle cerebral artery. Morphological alterations suggest a shift in microglia functionality integrated in the inflammatory response after stroke. Results show that CX3CR1 deficiency has no beneficial effect on lesion size neither it affects early functional outcome after stroke.
we demonstrated that CX3CR1(Lo)CCR2 (zeige CCR2 Antikörper)(Hi) monocytes were recruited to the GBM, where they transitioned to CX3CR1(Hi)CCR2 (zeige CCR2 Antikörper)(Lo) macrophages and CX3CR1(Hi)CCR2 (zeige CCR2 Antikörper)(-) microglia-like cells. Infiltrating macrophages/monocytes constituted approximately 85% of the total TAM (zeige CCNA1 Antikörper) population, with resident microglia accounting for the approximately 15% remaining.
CXCR4 (zeige CXCR4 Antikörper), CCR2 (zeige CCR2 Antikörper), and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung differentially.
Published data show that genetic deletion of CX3CR1, a microglia-specific chemokine receptor, promotes recovery after traumatic spinal cord injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the lesion epicenter. Data in the current manuscript indicate that CX3CR1 deletion changes microglia and macrophage function, creating a tissue microenvironment that enhances endogenous repair.
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
, CX3C chemokine receptor 1
, G protein-coupled receptor 13
, G-protein coupled receptor 13
, beta chemokine receptor-like 1
, chemokine (C-C) receptor-like 1
, chemokine (C-X3-C) receptor 1
, fractalkine receptor
, chemokine (C-C motif) receptor-like 1
, CX3C chemokine receptor 1-like
, c-C chemokine receptor type 11-like
, C-X-C chemokine receptor type 1
, chemokine receptor CXCR1
, Fractalkine receptor
, chemokine receptor 1
, chemokine (C-X3-C motif) receptor 1