PVRL3 Proteine (PVRL3)

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Synonyme:
2610301B19Rik, 3000002N23Rik, 4921513D19Rik, AA407785, AU016832, AW538082, CD113, CDW113, NECTIN-3, PPR3, PRR3, PVRL3, PVRR3
alle Proteine anzeigen Gen GeneID UniProt
PVRL3 25945 Q9NQS3
PVRL3 58998 Q9JLB9
Ratte PVRL3 PVRL3 288124  

PVRL3 Proteine (PVRL3) nach Spezies

Weitere Proteine zu PVRL3 Interaktionspartnern

Human Poliovirus Receptor-Related 3 (PVRL3) Interaktionspartner

  1. Data suggest that 3 independent regions of TcdB (Clostridium difficile toxin B; 1372-1493, 1493-1848, 1851-2366) contribute to binding and entry of TcdB into mammalian cells; residues 1372-1493 are sufficient for interaction with PVRL3.

  2. Expression of nectin-3 in pancreatic cancer can be a prognostic factor.

  3. PVRL3 is a physiologically relevant binding partner that can serve as a target for the prevention of TcdB-induced cytotoxicity in C. difficile infection.

  4. Nectin-3 is associated with the formation of cell junctions and be a putative suppressor molecule to the invasion of breast cancer cells.

  5. Nectin-3 trans-interacts with Nectin-2 (zeige PVRL2 Proteine) to promote lymphocyte and monocyte extravasation.

  6. Data suggest that expression of nectin-3 is up-regulated in eutopic endometrium of patients with endometriosis as compared with control subjects and up-regulated in all endometriotic lesions investigated compared with eutopic endometrium.

Mouse (Murine) Poliovirus Receptor-Related 3 (PVRL3) Interaktionspartner

  1. -afadin-specific C-terminal inserts may be involved in its preference of binding to nectin-3 and raise the possibility that there are proteins other than nectins that more preferentially bind s-afadin than l-afadin.

  2. owing to the loss of Nectin-3, hair cells contact each other inappropriately and form abnormal junctions, ultimately resulting in abnormal hair bundle orientation and morphology

  3. Results indicate that PLEKHA7 plays a cooperative role with nectin and afadin in the proper formation of Adherens junction (AJ) in epithelial cell.

  4. This study demonstrated that nectin1- and nectin3-mediated interactions between Cajal-Retzius cells cells and migrating neurons are critical for radial migration.

  5. Cell adhesion molecule (zeige MCAM Proteine) nectin-3 is required for the effects of corticotropin releasing hormone (zeige CRH Proteine) receptor (zeige NR4A1 Proteine) (CRHR)1 (zeige CRHR1 Proteine) on cognition and structural remodeling after early-life stress exposure.

  6. Nectin-3, which forms hetero-trans-dimers with nectin-1 (zeige PVRL1 Proteine), undergoes intramembrane cleavage mediated by PS1 (zeige PSEN1 Proteine)/gamma-secretase.

  7. hair cells and supporting cells express nectin-1 (zeige PVRL1 Proteine) and -3, respectively; their interaction mediates the heterotypic adhesion between these 2 cell types; nectin-1 (zeige PVRL1 Proteine) and -3 promote the formation of the checkerboard-like pattern of the auditory epithelia

  8. Results suggest that heterophilic interaction between nectin-1 (zeige PVRL1 Proteine) and nectin-3 recruits desmosomal junctions, and that these are required for proper enamel formation.

  9. nectin-afadin system plays essential roles in coupling cell-cell adhesion and the cortical actin scaffold in spermatids at Sertoli-spermatid junctions and in subsequent sperm morphogenesis

  10. Overexpressed nectin recruited N-cadherin DN to the nectin-based cell-cell adhesion sites in an afadin-dependent manner.

PVRL3 Protein Überblick

Protein Überblick

This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with PVRL3

  • poliovirus receptor-related 3 (Pvrl3)
  • poliovirus receptor-related 3 (PVRL3)
  • poliovirus receptor-related protein 3-like (LOC100518152)
  • poliovirus receptor-related 3 (LOC100350924)
  • poliovirus receptor-related 3 (pvrl3)
  • 2610301B19Rik Protein
  • 3000002N23Rik Protein
  • 4921513D19Rik Protein
  • AA407785 Protein
  • AU016832 Protein
  • AW538082 Protein
  • CD113 Protein
  • CDW113 Protein
  • NECTIN-3 Protein
  • PPR3 Protein
  • PRR3 Protein
  • PVRL3 Protein
  • PVRR3 Protein

Bezeichner auf Proteinebene für PVRL3

poliovirus receptor-related 3 , poliovirus receptor-related protein 3-like , nectin 3 , poliovirus receptor-related protein 3 , nectin-3

GENE ID SPEZIES
100732753 Cavia porcellus
478559 Canis lupus familiaris
100518152 Sus scrofa
460576 Pan troglodytes
100350924 Oryctolagus cuniculus
100414225 Callithrix jacchus
100439172 Pongo abelii
100549194 Meleagris gallopavo
100560246 Anolis carolinensis
100579224 Nomascus leucogenys
25945 Homo sapiens
58998 Mus musculus
288124 Rattus norvegicus
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