anti-ACTN2 (ACTN2) Antikörper

anti-Actinin, alpha 2 Antikörper (ACTN2)
Auf finden Sie aktuell 86 Actinin, alpha 2 (ACTN2) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ACTN2 Kits (24) und ACTN2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 127 ACTN2 Produkte verfügbar.
1110008F24Rik, ACTN2, CMD1AA, MGC89234, wu:fd44c03, zgc:123223
Alle Antikörper anzeigen Gen GeneID UniProt
ACTN2 11472 Q9JI91
ACTN2 291245  
ACTN2 88 P35609

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-ACTN2 (ACTN2) Antikörper

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anti-Mouse (Murine) ACTN2 Antikörper:

anti-Rat (Rattus) ACTN2 Antikörper:

anti-Human ACTN2 Antikörper:

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Am meisten referenzierte anti-ACTN2 Antikörper

  1. Human Polyclonal ACTN2 Primary Antibody für EIA, WB - ABIN950370 : Chiu, Bagnall, Ingles, Yeates, Kennerson, Donald, Jormakka, Lind, Semsarian: Mutations in alpha-actinin-2 cause hypertrophic cardiomyopathy: a genome-wide analysis. in Journal of the American College of Cardiology 2010 (PubMed)
    Zeige alle 5 Referenzen für 950370

  2. Cow (Bovine) Polyclonal ACTN2 Primary Antibody für IHC, WB - ABIN2776829 : Bos, Theis, Tajik, Gersh, Ommen, Ackerman: Relationship between sex, shape, and substrate in hypertrophic cardiomyopathy. in American heart journal 2008 (PubMed)
    Zeige alle 2 Referenzen für 2776829

  3. Human Monoclonal ACTN2 Primary Antibody für IHC (fro), IHC (p) - ABIN3043675 : Xiao, Zhang, Wang, Xu, Yu, Shen: Activation of an apoptotic signal transduction pathway involved in the upregulation of calpain and apoptosis-inducing factor in aldosterone-induced primary cultured cardiomyocytes. in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 (PubMed)
    Zeige alle 2 Referenzen für 3043675

  4. Human Monoclonal ACTN2 Primary Antibody für IHC (fro), IHC (p) - ABIN114743 : Goncharova, Kam, Geiger: The involvement of adherens junction components in myofibrillogenesis in cultured cardiac myocytes. in Development (Cambridge, England) 1992 (PubMed)
    Zeige alle 2 Referenzen für 114743

  5. Cow (Bovine) Polyclonal ACTN2 Primary Antibody für WB - ABIN2780085 : Hirschy, Schatzmann, Ehler, Perriard: Establishment of cardiac cytoarchitecture in the developing mouse heart. in Developmental biology 2006 (PubMed)

  6. Cow (Bovine) Polyclonal ACTN2 Primary Antibody für IHC, WB - ABIN2776830 : Eldstrom, Choi, Steele, Fedida: SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism. in FEBS letters 2003 (PubMed)

Weitere Antikörper gegen ACTN2 Interaktionspartner

Mouse (Murine) Actinin, alpha 2 (ACTN2) Interaktionspartner

  1. Data suggest that kindlin-2 (Kind2/Fermt2 (zeige FERMT2 Antikörper)) interacts with actin alpha 2 (Actn2) and integrin beta 1 (Itgb1 (zeige ITGB1 Antikörper)) and co-localizes to cardiac sarcomere at Z-disc; knockdown of Kind2 (zeige FERMT2 Antikörper) leads to dissociation of Actn2 and Itgb1 (zeige ITGB1 Antikörper).

  2. Data show that alpha-Actinin 2 and CaMKIIalph (zeige NEXN Antikörper)a exist in complex with GluN2B in fo (zeige CAMK2 Antikörper)rebrain.

  3. Data demonstrated that the Z-disk proteins, ZASP (zeige LDB3 Antikörper), titin (zeige TTN Antikörper) and vinculin (zeige VCL Antikörper) preferentially bind to alpha-actinin-2. Thus, the loss of alpha-actinin-3 (zeige ACTN3 Antikörper) changes the overall protein composition of fast fiber Z-disks and alters their elastic properties.

  4. alpha-Actinin (zeige ACTN1 Antikörper), rapsyn (zeige RAPSN Antikörper), and surface AChR form a ternary complex.

  5. BPAG1 (zeige DST Antikörper)-b was detectable in vitro and in vivo as a high molecular mass protein in striated (zeige NSDHL Antikörper) and heart muscle cells, co-localizing with alpha-actinin-2 and partially with the cytolinker plectin (zeige PLEC Antikörper) as well as with the intermediate filament protein desmin (zeige DES Antikörper).

  6. demonstrate that proper membrane localization of a small-conductance Ca(2 (zeige CA2 Antikörper)+)-activated K(+) channel (zeige KCNC4 Antikörper) (SK2 (zeige PAPSS2 Antikörper) or K(Ca)2.2) is dependent on its interacting protein, alpha-actinin2, a major F-actin crosslinking protein (zeige MACF1 Antikörper).

Human Actinin, alpha 2 (ACTN2) Interaktionspartner

  1. These results provide new insights into the regulation of SK2 (zeige KCNN2 Antikörper) channel trafficking by the cytoskeletal proteins FLNA (zeige FLNA Antikörper) and alpha-actinin2, involving distinct recycling pathways

  2. the interaction between GNE (zeige GNE Antikörper) and alpha-actinin 1 (zeige ACTN1 Antikörper) and alpha-actinin 2 occur at different sites in the alpha-actinin (zeige ACTN1 Antikörper) molecules and that for alpha-actinin 2 the interaction site is located at the C-terminus of the protein.

  3. study strengthens the hypothesis that ACTN2 influences caries risk.

  4. The novel heterozygous missense sequence variant ACTN2 cosegregated with a complex cardiomyopathic trait, characterized by the interplay of midapical, nonobstructive HCM, early onset of AF and AV block, as well as regional LV noncompaction.

  5. Clinical evaluation of an Australian family revealed diverse cardiac pathologies in four affected members and genetic testing of the exome identified a pathogenic ACTN2 heterozygous variant (Ala119Thr) that co-segregated with disease.

  6. Study reports a complete high-resolution structure of the 200 kDa alpha-actinin-2 dimer from striated (zeige NSDHL Antikörper) muscle and explore its functional implications on the biochemical and cellular level.

  7. This study generated the genomic sequences of K88-positive and F18 (zeige MAMLD1 Antikörper)-positive porcine enteroteoxigenic E. coli (ETEC) strains and examined the phylogenetic distribution of clinical porcine ETEC strains and their plasmid-associated genetic content.

  8. Findigs show that the F-actin-binding protein (zeige SHROOM3 Antikörper) alpha-actinin-2 targets CaMKIIalpha (zeige CAMK2 Antikörper) to F-actin in cells by binding to the CaMKII (zeige CAMK2G Antikörper) regulatory domain.

  9. data provide functional evidence that the primary sequences of alpha-actinin-2 and alpha-actinin-3 (zeige ACTN3 Antikörper) evolved differences to optimize their functions

  10. This is the first genome-wide linkage analysis that shows mutations in ACTN2 cause HCM

Zebrafish Actinin, alpha 2 (ACTN2) Interaktionspartner

ACTN2 Antigen-Profil

Beschreibung des Gens

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.

Alternative names and synonyms associated with ACTN2

  • actinin, alpha 2 (actn2) Antikörper
  • actinin, alpha 2 (ACTN2) Antikörper
  • actinin alpha 2 (Actn2) Antikörper
  • actinin, alpha 2 (Actn2) Antikörper
  • 1110008F24Rik Antikörper
  • ACTN2 Antikörper
  • CMD1AA Antikörper
  • MGC89234 Antikörper
  • wu:fd44c03 Antikörper
  • zgc:123223 Antikörper

Bezeichner auf Proteinebene für ACTN2

actinin, alpha 2 , alpha 2 actinin , alpha-actinin-2-like , F-actin cross-linking protein , alpha-actinin skeletal muscle , alpha-actinin-2

448602 Xenopus (Silurana) tropicalis
469156 Pan troglodytes
100033870 Equus caballus
100481134 Ailuropoda melanoleuca
11472 Mus musculus
291245 Rattus norvegicus
88 Homo sapiens
396263 Gallus gallus
479191 Canis lupus familiaris
100157406 Sus scrofa
536607 Bos taurus
641575 Danio rerio
432169 Xenopus laevis
100350274 Oryctolagus cuniculus
100712846 Cavia porcellus
101116372 Ovis aries
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