anti-LIM Domain Kinase 1 (LIMK1) Antikörper

Bezeichnung:
anti-LIM Domain Kinase 1 Antikörper (LIMK1)
Auf www.antikoerper-online.de finden Sie aktuell 221 LIM Domain Kinase 1 (LIMK1) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LIM Domain Kinase 1 Proteine (11) und LIM Domain Kinase 1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 243 LIM Domain Kinase 1 Produkte verfügbar.
Synonyme:
GB16654, LIMK, LIMK-1, LIMK1, xlimk1
Alle Antikörper anzeigen Gen GeneID UniProt
LIMK1 3984 P53667
LIMK1 65172  
LIMK1 16885 P53668

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-LIM Domain Kinase 1 (LIMK1) Antikörper

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anti-Human LIM Domain Kinase 1 Antikörper:

anti-Rat (Rattus) LIM Domain Kinase 1 Antikörper:

anti-Mouse (Murine) LIM Domain Kinase 1 Antikörper:

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Am meisten referenzierte anti-LIM Domain Kinase 1 Antikörper

  1. Human Polyclonal LIM Domain Kinase 1 Primary Antibody für EIA, IHC (p) - ABIN360142 : Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. in The Journal of biological chemistry 2000 (PubMed)
    Zeige alle 5 Referenzen für 360142

  2. Human Polyclonal LIM Domain Kinase 1 Primary Antibody für IHC (p), WB - ABIN392258 : Maekawa, Ishizaki, Boku, Watanabe, Fujita, Iwamatsu, Obinata, Ohashi, Mizuno, Narumiya: Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. in Science (New York, N.Y.) 1999 (PubMed)
    Zeige alle 4 Referenzen für 392258

  3. Human Monoclonal LIM Domain Kinase 1 Primary Antibody für IF, WB - ABIN968654 : Edwards, Gill: Structural features of LIM kinase that control effects on the actin cytoskeleton. in The Journal of biological chemistry 1999 (PubMed)
    Zeige alle 4 Referenzen für 968654

  4. Human Polyclonal LIM Domain Kinase 1 Primary Antibody für ELISA, WB - ABIN1533778 : Mizuno, Okano, Ohashi, Nunoue, Kuma, Miyata, Nakamura: Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif. in Oncogene 1994 (PubMed)
    Zeige alle 3 Referenzen für 1533778

  5. Human Polyclonal LIM Domain Kinase 1 Primary Antibody für ICC, IF - ABIN4330979 : Park, Agnihotri, Golbourn, Bertrand, Luck, Sabha, Smith, Byron, Zadeh, Croul, Berens, Rutka: Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway. in Oncotarget 2014 (PubMed)
    Zeige alle 2 Referenzen für 4330979

  6. Human Polyclonal LIM Domain Kinase 1 Primary Antibody für IF, IHC (p) - ABIN196830 : Edwards, Sanders, Bokoch, Gill: Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. in Nature cell biology 1999 (PubMed)
    Zeige alle 2 Referenzen für 196830

  7. Human Polyclonal LIM Domain Kinase 1 Primary Antibody für ICC, IF - ABIN4330977 : Gupta, Yadav, Pavuluri, Morley, Stairs, Dravid: Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity. in Neuropharmacology 2015 (PubMed)

Weitere Antikörper gegen LIM Domain Kinase 1 Interaktionspartner

Human LIM Domain Kinase 1 (LIMK1) Interaktionspartner

  1. Report structural basis for noncanonical substrate recognition of cofilin-1/LIMK1 to regulation actin cytoskeleton dynamics.

  2. LIMK1 expression is negatively regulated in granular layers-negative psoriatic epidermis or IL-22 (zeige IL22 Antikörper)/IL-24 (zeige IL24 Antikörper)-treated hyperproliferative reconstituted epidermis. These findings suggest a novel regulatory mechanism and a potent role of LIMK1 in psoriatic epidermis.

  3. Therefore, miR (zeige MLXIP Antikörper)-138/LIMK1/cofilin (zeige CFL1 Antikörper) may be considered a potential therapeutic target for the treatment of non-small cell lung cancer

  4. This study showed that LIMK1 messenger RNA levels was significantly upregulated in subjects with schizophrenia in laminar and cellular samples.

  5. Gene knockdown/rescue experiments reveal that LIMK1 palmitoylation is essential for normal spine actin polymerization, for spine-specific structural plasticity and for long-term spine stability.

  6. LIMK1 is overexpressed in endometrial stromal cells.

  7. Data show that the downregulation of miR (zeige MLXIP Antikörper)-138 induced the upregulation of Limk1 in ovarian cancer (OC) cells suggesting that these 2 genes may play a key role in the migration and invasion of OC cells.

  8. LIMK1 is overexpressed in gastric cancer.

  9. Results show that in addition to a potential role in promoting metastasis, changes in LIMK1 and LIMK2 (zeige LIMK2 Antikörper) expression and/or activity might contribute to AR function in prostate cancer via regulation of microtubule cytoskeletal dynamics.

  10. CXCL12 (zeige CXCL12 Antikörper)/CXCR4 (zeige CXCR4 Antikörper) signaling has a role in docetaxel-induced microtubule stabilization via p21-activated kinase 4 (zeige PAK4 Antikörper)-dependent activation of LIMK1

Xenopus laevis LIM Domain Kinase 1 (LIMK1) Interaktionspartner

  1. bone morphogenetic protein receptor II (BMPRII (zeige BMPR2 Antikörper)) is a major regulator of LIMK1 in extending RGC axons, as expression of a BMPRII (zeige BMPR2 Antikörper) lacking the LIMK1 binding region caused a dramatic shortening of the axons

Mouse (Murine) LIM Domain Kinase 1 (LIMK1) Interaktionspartner

  1. LIMK1 negatively regulated neuronal migration by affecting the neuronal cytoskeleton and that its effects were partly mediated by cofilin (zeige CFL1 Antikörper) phosphorylation

  2. Social isolation resulted in up-regulation of Limk-1 mRNA expression in the cerebral cortex.

  3. The data emphasize the importance of the PLCeta2 EF-hand domain and articulation of PLCeta2 with LIMK-1 in regulating neuritogenesis.

  4. Our study indicates that there is a connection between LIMK1 and AD in the mouse model of AD.

  5. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.

  6. LIMK1 and Cofilin (zeige CFL1 Antikörper) phosphorylation depends on PKA and is essential for mouse sperm acrosomal exocytosis

  7. These results provide strong evidence that LIMK1 deletion is sufficient to lead to a long-term memory deficit and that this deficit is attributable to CREB (zeige CREB1 Antikörper) hypofunction.

  8. the conserved region in the LIMK1 3' UTR (zeige UTS2R Antikörper) is involved in regulating LIMK1 expression at the post-transcriptional level

  9. LIMK1 plays a novel role in selectively mediating GPIb-IX-dependent TXA2 (zeige TBXA2R Antikörper) synthesis and thrombosis.

  10. data support the hypothesis that LIMK1 is required for normal osteoblast differentiation. In addition, its absence leads to increased cytoskeletal remodeling and bone resorption in osteoclasts

LIM Domain Kinase 1 (LIMK1) Antigen-Profil

Beschreibung des Gens

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with LIM Domain Kinase 1 (LIMK1)

  • LIM domain kinase 1 (LIMK1) Antikörper
  • LIM domain kinase 1a (limk1a) Antikörper
  • LIM domain kinase 1 (limk1) Antikörper
  • LIM domain kinase 1 (CpipJ_CPIJ000717) Antikörper
  • LIM-kinase1 (LIMK1) Antikörper
  • LIM domain kinase 1 (Limk1) Antikörper
  • LIM-domain containing, protein kinase (Limk1) Antikörper
  • GB16654 Antikörper
  • LIMK Antikörper
  • LIMK-1 Antikörper
  • LIMK1 Antikörper
  • xlimk1 Antikörper

Bezeichner auf Proteinebene für LIMK1

LIM domain kinase 1 , LIM-kinase1 , LIM motif-containing protein kinase , LIM motif-containing protein kinase 1 , LIM-domain containing protein kinase 1 , LIM-domain containing, protein kinase 1 , LIMK-1 , chLIMK1 , KIZ-1

GENE ID SPEZIES
489800 Canis lupus familiaris
100062100 Equus caballus
735292 Danio rerio
780362 Xenopus (Silurana) tropicalis
6031483 Culex quinquefasciatus
413152 Apis mellifera
100286874 Sus scrofa
3984 Homo sapiens
65172 Rattus norvegicus
463466 Pan troglodytes
100294566 Pongo abelii
535225 Bos taurus
373922 Gallus gallus
397696 Xenopus laevis
16885 Mus musculus
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