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anti-PKD2 (PKD2) Antikörper

Bezeichnung:
anti-Protein Kinase D2 Antikörper (PKD2)
Auf www.antikoerper-online.de finden Sie aktuell 123 Protein Kinase D2 (PKD2) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PKD2 Proteine (11) und PKD2 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 150 PKD2 Produkte verfügbar.
Synonyme:
AI325941, APKD2, nPKC-D2, Pc-2, PC2, PKD2, PKD4, PRKD2, RGD1308054, TRPP2

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anti-Human PKD2 Antikörper:

anti-Mouse (Murine) PKD2 Antikörper:

anti-Rat (Rattus) PKD2 Antikörper:

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Am meisten referenzierte anti-PKD2 Antikörper

  1. Human Polyclonal PKD2 Primary Antibody für IP, WB - ABIN152061 : Liu, Evans, Britton, Zachary: The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis. in Oncogene 2008 (PubMed)
    Zeige alle 8 Referenzen für ABIN152061

  2. Human Polyclonal PKD2 Primary Antibody für EIA, IHC (p) - ABIN360330 : Stayner, Zhou: Polycystin channels and kidney disease. in Trends in pharmacological sciences 2001 (PubMed)
    Zeige alle 5 Referenzen für ABIN360330

Weitere Antikörper gegen PKD2 Interaktionspartner

Human Protein Kinase D2 (PKD2) Interaktionspartner

  1. SNPs in and near PKD2 showed significant evidence of association in individual samples of black adults (rs17013735, P-value=0.0009) and white adults (rs11938025; P-value=0.0005; rs2725270, P-value=0.003).

  2. Pancreatic cysts were more prevalent in patients with ADPKD with PKD2 mutation than in control subjects or patients with PKD1 (zeige PKD1 Antikörper) mutation.

  3. This study discovered and characterized a novel, highly conserved N-terminal domain, comprising 92 amino acids, which mediates dimerization of Protein Kinase D (PKD) isoforms, PKD1 (zeige PKD1 Antikörper), PKD2, and PKD3 (zeige PRKD3 Antikörper) monomers.

  4. This suggests that a precise dosage of PC2 (zeige KRT6B Antikörper) is necessary for an adequate mechanosensitive alpha-actinin (zeige ACTN1 Antikörper) recruitment at junctions.

  5. PKD1 (zeige PKD1 Antikörper) and PKD2 are susceptibility genes for familial intracranial aneurysms in a Japanese population.

  6. Novel PKD2 mutations in Chinese autosomal dominant polycystic kidney disease patients

  7. Two neutral missense PKD2 variants indentified in exon1 c.83G>C (p.R28P) and c.568G>A (p.A190T), which the former segregate with the mutation in affected relatives, and two new intronic and 3'UTR (zeige UTS2R Antikörper) variants, c.1548+63C>T and c.*363delA.

  8. this study presents the cryo-EM structure of PKD2 in lipid bilayers at 3.0 A resolution, which establishes PKD2 as a homotetrameric ion channel and provides insight into potential mechanisms for its activation.

  9. PCs expression and p53 (zeige TP53 Antikörper) activation as a regulator of cell proliferation were further evaluated in vivo and in 69 advanced human carotid atherosclerotic plaques.

  10. PKD2 and RSK1 (zeige RPS6KA1 Antikörper) regulate integrin beta4 phosphorylation at threonine 1736 to stabilize keratinocyte cell adhesion and its hemidesmosomes.

Mouse (Murine) Protein Kinase D2 (PKD2) Interaktionspartner

  1. Our studies demonstrate that PKD1 (zeige PKD1 Antikörper)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (zeige DGKA Antikörper) effect on MVB secretory traffic.

  2. Results reveal that whereas protein kinase D1 (zeige PRKD1 Antikörper) and protein kinase D2 are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  3. PKD2 acted as an amplification checkpoint for antigen-stimulated digital cytokine responses and translated the differential strength of TCR signaling to determine the number of naive CD8 (zeige CD8A Antikörper)(+) T cells that became effector cells.

  4. Protein kinase D2 promotes in vitro osteoclast differentiation and fusion

  5. A bioinformatic screen identified the serine-threonine kinase (zeige CDK4 Antikörper) protein kinase D2 (PRKD2) as a potential effector of GABP in hematopoietic stem cells

  6. Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by alpha/beta mature TCR complexes in peripheral T-cells.

  7. PKD2 is a common signaling target downstream of various agonist receptors in platelets and G(q)-mediated signals along with calcium and novel PKC (zeige PKC Antikörper) isoforms, in particular, PKCdelta (zeige PKCd Antikörper) activate PKD2 in platelets.

  8. Data demonstrate that, unlike PKD1 (zeige PKD1 Antikörper), PKD2 catalytic activity is dispensable for normal embryogenesis.

  9. PKD2, like PKD (zeige PRKD1 Antikörper), facilitates mitogenesis in 3T3 cells

PKD2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PKD2

  • protein kinase D2 (PRKD2) Antikörper
  • polycystic kidney disease 2 (autosomal dominant) (PKD2) Antikörper
  • protein kinase D2 (Prkd2) Antikörper
  • AI325941 Antikörper
  • APKD2 Antikörper
  • nPKC-D2 Antikörper
  • Pc-2 Antikörper
  • PC2 Antikörper
  • PKD2 Antikörper
  • PKD4 Antikörper
  • PRKD2 Antikörper
  • RGD1308054 Antikörper
  • TRPP2 Antikörper

Bezeichner auf Proteinebene für PKD2

protein kinase D2 , serine/threonine-protein kinase D2-like , R48321 , autosomal dominant polycystic kidney disease type II protein , polycystin-2 , polycystwin , transient receptor potential cation channel, subfamily P, member 2 , serine/threonine-protein kinase D2 , nPKC-D2

GENE ID SPEZIES
468929 Pan troglodytes
782793 Bos taurus
100407181 Callithrix jacchus
100471375 Ailuropoda melanoleuca
5311 Homo sapiens
25865 Homo sapiens
101540 Mus musculus
292658 Rattus norvegicus
484427 Canis lupus familiaris
100517036 Sus scrofa
100355908 Oryctolagus cuniculus
100717067 Cavia porcellus
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