Mu Opioid Receptor 1 Proteine (OPRM1)

Opioid Receptor, mu 1 Proteine (OPRM1)
Auf finden Sie aktuell 6 Opioid Receptor, mu 1 (OPRM1) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Mu Opioid Receptor 1 Antikörper (123) und Mu Opioid Receptor 1 Kits (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 158 Mu Opioid Receptor 1 Produkte verfügbar.
6430411K18Rik, LMOR, M-OR-1, Mar, Mart1, MOP, MOP-R, mor, MOR-1, MOR-1O, MOR1, MORA, muOR, OPRM, OPRM1, Oprrm1, or2, Peg11, ZFOR2
alle Proteine anzeigen Gen GeneID UniProt
Ratte OPRM1 OPRM1 81829 P04636
OPRM1 4988 P35372
OPRM1 18390 P42866

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Am meisten referenzierte Mu Opioid Receptor 1 Proteine

  1. Human Mu Opioid Receptor 1 Protein expressed in Wheat germ - ABIN1313419 : Perlikowska, Gach, Fichna, Toth, Walkowiak, do-Rego, Janecka: Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2. in Bioorganic & medicinal chemistry 2009 (PubMed)

Weitere Proteine zu Mu Opioid Receptor 1 Interaktionspartnern

Zebrafish Opioid Receptor, mu 1 (OPRM1) Interaktionspartner

  1. MicroRNA miR (zeige MYLIP Proteine)-212/132 cluster is actively repressing the expression of mu opioid receptor (Oprm1) by targeting a sequence in the 3' UTR of its mRNA.

  2. demonstrate that zfMOR exhibits a pharmacological profile similar to that of the mammalian MOR.

Human Opioid Receptor, mu 1 (OPRM1) Interaktionspartner

  1. These results do not support strong modulatory effects of OPRM1 genetic variation on opioid receptor antagonist attenuation of alcohol- and food-related behaviors.

  2. AG and GG genotypes of OPRM1 rs1799971 were associated with a decreased risk of CVS ( P <0.05). In addition, AG and GG genotypes of OPRM1 rs1799971 were correlated with migraine episodes and a family history of migraines.

  3. Subjects with schizophrenia who had the OPRM1 *G genotype smoked more cigarettes per day than the AA allele carriers with schizophrenia. In bipolar patients, there were no OPRM1 genotype differences in smoking status.

  4. The MOR-Gal1R heteromer can explain previous results showing antagonistic galanin (zeige GAL Proteine)-opioid interactions and offers a new therapeutic target for the treatment of opioid use disorder

  5. This study examined associations of the mu opioid receptor gene with several self-report measures relating to personality. These analyses revealed a pattern of Gene x Environment interactions that are consistent with the view that the G allele confers greater vulnerability than the A allele to adverse effects of childhood social adversity on adult personality qualities related to social connection.

  6. MOR is present in human endometrium and levels change during the menstrual cycle.

  7. Data show the multimicrosecond, all-atom molecular dynamics (MD) simulations of the binding of oliceridine (TRV-130) to the activated mu-opioid receptor (MOR) crystal structure.

  8. These results establish the role of hnRNP K and PCPB1 in the translational control of morphine-induced MOR expression in human neuroblastoma (NMB) cells as well as cells stably expressing MOR (NMB1).

  9. distinct ligands can leverage specific sequence elements on microR to regulate receptor endocytic lifetimes and the magnitude of arrestin (zeige SAG Proteine)-mediated signaling.

  10. AA patients for opioid receptor mu 1 single nucleotide polymorphism had significantly lower cognitive function than AG patients.

Mouse (Murine) Opioid Receptor, mu 1 (OPRM1) Interaktionspartner

  1. The data show that somatic MORs in POMC (zeige POMC Proteine) neurons couple to multiple effectors that have differential sensitivity to desensitization of the receptor.

  2. C termini generated from 3' alternative splicing of the mu opioid receptor gene are pharmacologically distinct.

  3. Double mothering normalized the abnormal response to maternal separation in Oprm1-knockout mice, in an animal model of Autism.

  4. OPRM1, expressed by primary afferent nociceptors, initiates opiate tolerance and opioid-induced hyperalgesia development.

  5. Study reveals dissociable Mu opioid receptors (MOR) functions across mesocorticolimbic networks. Beyond a role in reward processing, operating at the level of local ventral tegmental area neurons, MORs also moderate motivation for appetitive stimuli within forebrain circuits that drive motivated behaviors.

  6. MOR-T394 mutation or polymorphisms could be a risk factor in developing opioid abuse and addiction and therefore be used as a new biomarker in prediction and prevention of opioid abuse and addiction

  7. MOR epigenetic regulation requires multiple coordinated signals converging at the MOR promoter, involving mitogen-activated protein kinase (zeige MAPK1 Proteine) (MAPK (zeige MAPK1 Proteine)) activation and mitogen- and stress-activated protein kinase 1 (zeige RPS6KA5 Proteine).

  8. inhibition of mu-opioid receptor expression blocks morphine and DAMGO increases in the translocation of NF-kB p65 protein in microglia.a low dose of morphine, exerting its effects via the mu-opioid receptor, increases the DNA-binding activity of NF-kB via PKCepsilon, while a high dose of morphine triggers a nonopiate receptor response mediated by TLR4 and, interestingly, PKC signalling

  9. Paternally expressed 11/Retrotransposon-like 1 (Peg11/Rtl1) knockout (KO) mice show mid- to late fetal lethality or late fetal growth retardation associated with frequent neonatal lethality

  10. findings indicate that G9a (zeige EHMT2 Proteine) contributes critically to transcriptional repression of MORs in primary sensory neurons in neuropathic pain. G9a (zeige EHMT2 Proteine) inhibitors may be used to enhance the opioid analgesic effect in the treatment of chronic neuropathic pain.

Cow (Bovine) Opioid Receptor, mu 1 (OPRM1) Interaktionspartner

Rhesus Monkey Opioid Receptor, mu 1 (OPRM1) Interaktionspartner

  1. Coactivation of mu opioid receptors with nociceptin receptors produces synergistic antinociception.

  2. Thisstudy adds to the growing literature showing that variation in the mu-opioid receptor gene OPRM1 is associated with social attachment and rejection.

  3. OPRM1 gene variation influences hypothalamic-pituitary-adrenal axis function in response to a variety of stressors.

  4. findings suggest a role for OPRM1 variation in the expression of attachment behavior, especially as a function of separation from the caregiver

Mu Opioid Receptor 1 (OPRM1) Protein Überblick

Protein Überblick

This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Mu Opioid Receptor 1 (OPRM1)

  • opioid receptor, mu 1 (oprm1)
  • opioid receptor, mu 1 (OPRM1)
  • outer membrane efflux protein (oprM1)
  • outer membrane protein OprM (oprM1)
  • malate dehydrogenase 2, NAD (mitochondrial) (Mdh2)
  • opioid receptor, mu 1 (Oprm1)
  • retrotransposon-like 1 (Rtl1)
  • 6430411K18Rik Protein
  • LMOR Protein
  • M-OR-1 Protein
  • Mar Protein
  • Mart1 Protein
  • MOP Protein
  • MOP-R Protein
  • mor Protein
  • MOR-1 Protein
  • MOR-1O Protein
  • MOR1 Protein
  • MORA Protein
  • muOR Protein
  • OPRM Protein
  • OPRM1 Protein
  • Oprrm1 Protein
  • or2 Protein
  • Peg11 Protein
  • ZFOR2 Protein

Bezeichner auf Proteinebene für Opioid Receptor, mu 1 Proteine (OPRM1)

ZfMOR , mu-type opioid receptor , opioid receptor, mu 1 , mu-opioid receptor , outer membrane efflux protein , outer membrane protein OprM , malate dehydrogenase, mitochondrial , M-OR-1 , MOR-1 , MUOR1 , mu opioid receptor splice variant rMOR-1S , mu opioid receptor splice variant rMOR-1Z , opioid receptor B , micro opioid receptor isoform hMOR-1A2 , mu opiate receptor , mu opioid receptor hMOR-1a , MOP receptor , mu opioid receptor , mammalian retrotransposon derived protein 1 , paternally expressed gene 11 protein , retrotransposon-derived protein PEG11 , retrotransposon-like protein 1

65088 Danio rerio
484041 Canis lupus familiaris
100033967 Equus caballus
100585188 Nomascus leucogenys
4606278 Azoarcus sp. BH72
10918065 Cupriavidus necator N-1
81829 Rattus norvegicus
25601 Rattus norvegicus
4988 Homo sapiens
18390 Mus musculus
100379267 Cavia porcellus
396802 Sus scrofa
281958 Bos taurus
472165 Pan troglodytes
574141 Macaca mulatta
353326 Mus musculus
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