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anti-Human COX2 Antikörper:
anti-Mouse (Murine) COX2 Antikörper:
anti-Rat (Rattus) COX2 Antikörper:
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Human Monoclonal COX2 Primary Antibody für WB - ABIN283213
Cheng, Whitehead, Hachinski, Cechetto: Effects of pyrrolidine dithiocarbamate on beta-amyloid (25-35)-induced inflammatory responses and memory deficits in the rat. in Neurobiology of disease 2006
sUV activated the transcription factors nuclear factor-kappaB and activator protein-1 (zeige FOSB Antikörper) which, in turn, induces COX-2 expression.
A single SNP (rs689466) localized at 5' -1192 of the PTGS2 (zeige PTGS2 Antikörper) gene exhibited significant association with febrile seizure (FS) based on case-control allelic association analyses. A significant decrease in the frequency of the G allele in FS was observed compared to that in controls. Using case-control genotypic association analysis, the -1192A allele is most likely to confer susceptibility to FS by a recessive action model.
The anticancer effects by 13'-COOHs appeared to be partially independent of inhibition of COX-2/5-LOX. Using liquid chromatography tandem mass spectrometry, we found that 13'-COOHs increased intracellular dihydrosphingosine and dihydroceramides after short-time incubation in HCT-116 cells, and enhanced ceramides while decreased sphingomyelins during prolonged treatment
Effects of pro-inflammatory cytokines, lipopolysaccharide and COX-2 mediators on human colonic neuromuscular function and epithelial permeability
High PTGS2 (zeige PTGS2 Antikörper) expression is associated with metastasis of esophageal squamous cell cancer.
Experimental results indicate that methylmercury inhibits the activity of protein tyrosine phosphatase 1B (zeige PTPN1 Antikörper), which in turn activates the epidermal growth factor receptor (zeige EGFR Antikörper)-p38 mitogen-activated protein kinase (zeige MAPK14 Antikörper) pathway that induces cyclooxygenase-2 (zeige PTGS2 Antikörper) expression.
Our data suggest that the molecular network including TSP-1 (zeige THBS1 Antikörper), TGF-beta1 (zeige TGFB1 Antikörper), and PGE2 might be involved in the pathogenesis of acute angle closure glaucoma.
the COX-2 -1195G>A gene polymorphism might be a potential risk factor for gastrointestinal cancers [review]
results demonstrated that XRCC5 (zeige XRCC5 Antikörper) promoted colon cancer growth by cooperating with p300 (zeige EP300 Antikörper) to regulate COX-2 expression, and suggested that the XRCC5 (zeige XRCC5 Antikörper)/p300 (zeige EP300 Antikörper)/COX-2 signaling pathway was a potential target in the treatment of colon cancers
we demonstrated that we could take the advantage of the common phenomenon of COX-2 overexpression in cancers to inhibit cancer cell migration and invasion
sUV activated the transcription factors nuclear factor-kappaB and activator protein-1 (zeige JUN Antikörper) which, in turn, induces COX-2 expression.
Results indicate that Cox-2 promotes Col10a1 (zeige COL10A1 Antikörper) expression and chondrocyte hypertrophy in vitro.
These data reveal important structure-function and signaling differences between the two FFA4 isoforms, and for the first time link FFA4 to modulation of ROS (zeige ROS1 Antikörper) in macrophages.
Our data suggest that there are physiologically important gender differences in hypoxic acclimatization in COX-2-deficient mice. The COX-2 signaling pathway appears to be required for acclimatization in oxygen-limiting environments only in males, whereas female COX-2-deficient mice may be able to access COX-2-independent mechanisms to achieve hypoxic acclimatization.
increased COX2 expression has an impact on the aging process
These results establish a novel signaling process whereby PAK1 (zeige PAK1 Antikörper) upregulates COX-2, reduces anandamide levels and restricts tonic endocannabinoids-mediated processes.
Angiotensin II-AT1-receptor (zeige AGTRAP Antikörper) signaling is necessary for COX-2-dependent normal postnatal nephrogenesis and maturation.
AhR (zeige AHR Antikörper) controls COX-2 protein via mRNA stability.
Podocyte-specific knockout of COX2 enhanced albuminuria and did not attenuate the histologic features of diabetic kidney disease.
Salt supplementation during the COX-2-dependent time frame of nephrogenesis partly reverses renal morphological defects in COX-2(-/-) mice and improves kidney function.
B1 receptors are coupled to COX2 (zeige PTGS2 Antikörper) in causing endothelium-independent contractions in endotoxin-treated pig coronary arteries
Expression of COX-2 (zeige PTGS2 Antikörper) was strongest in gilts with acute endometritis, but did not differ between those with chronic endometritis and normal endometrium.
Data indicate that the proton-pumping pathway of heart cytochrome c (zeige CYCS Antikörper) oxidase includes a hydrogen-bond network and a water channel (zeige AQP4 Antikörper) located in tandem between the positive and negative side of the mitochondrial membrane.
Study suggests that His503 is involved in the proton supply to the D-path as a proton acceptor in cytochrome c (zeige CYCS Antikörper) oxidase.
Data suggest that the axial Met residue moderately increased the redox potential of the Cu(A) site in cytochrome c (zeige CYCS Antikörper) oxidase.
Studies indicate that heart cytochrome c (zeige CYCS Antikörper) oxidase subunits I, II and III are encoded by the mitochondrial genome.
extensive pre- and intrapartal rise of COX (zeige COX7A1 Antikörper)-II expression in bovine placentomes with a 70-100-fold increase of COX (zeige COX7A1 Antikörper)-II-mRNA levels
Pretreatment of cells with selective COX-2 blocker etodolac markedly inhibited ICl.
Safflower injection may attenuate lung ischemia/reperfusion injury through inhibiting cyclooxygenase-2 (zeige PTGS2 Antikörper) expression.
The RNA interference targeting COX-2 can effectively inhibit the expression of COX-2 and MMP-2 (zeige MMP2 Antikörper) in IL-1alpha stimulated rabbit corneal stromal cells in vitro.
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
PGH synthase 2
, PHS II
, cyclooxygenase 2b
, prostaglandin G/H synthase 2
, prostaglandin H2 synthase 2
, cyclooxygenase 2
, glucocorticoid-regulated inflammatory cyclooxygenase
, macrophage activation-associated marker protein P71/73
, cytochrome c oxidase subunit II
, cytochrome c oxidase subunit ii
, cytochrome C oxidase subunit II